Clinical trials: Parodontitis
Periodontitis, Laser
Clinical Evaluation of the Effect of LANAP as an Adjunct Treatment in Management of Patients With Chronic Periodontitis
this study evaluate the effect of LANAP (Laser Assisted New Attachment Procedure) as an Adjunct Treatment in Management of Patients With Chronic Periodontitis and assay the effect of LANAP on periodontal indexes like BOP, CAL…
- Trial name
- NCT03365167
- Testing
- LANAP (Laser Assisted New Attachment Procedure), LANAP off
- Where
- Iran
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Tehran University of Medical Sciences
Chronic Periodontitis
Efficacy of Turmeric in Gingival Massaging and Adjunct to Scaling and Root Planing in Chronic Periodontitis Patient
Periodontal disease is considered as inflammatory, multifactorial, and threshold disease accompanied by destruction of periodontium and eventually the loss of natural teeth.
- Trial name
- NCT02890771
- Testing
- Tooth Brushing with Dentifrice, Turmeric Massaging, SRP with turmeric massaging
- Volunteers
- 91 people, healthy volunteers welcome
- Sponsor
- Government College of Dentistry, Indore
Periodontitis
A Clinical Trial to Evaluate the Effectiveness of Lactobacillus Reuteri for Periodontitis in a Chinese Population
The aim of this study is to determine the efficacy of application of Lactobacillus Reuteri probiotics therapy on clinical improvement and on microbial shift in Chinese periodontitis patients.
- Trial name
- NCT04129684
- Testing
- Probiotics
- Where
- China
- Volunteers
- 880 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Periodontal Diseases, Periodontitis
Assessment of Salivary GM-CSF, MIP, and IL-1β Levels in Subjects With Varying Periodontal Conditions
In order to determine the pathogenesis of chronic inflammatory diseases, the levels of various cytokines are examined in tissues and fluids taken from the body.
- Conditions
- Periodontal Diseases, Periodontitis, Gingivitis, Periodontal Health
- Trial name
- NCT06961409
- Testing
- Saliva obtaining
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Izmir Katip Celebi University
Tooth Loss
Tooth Loss Rate and Its Associated Factors: a Retrospective Cross-sectional Study With up to 50 Years of Follow-up.
This study will evaluate, in an adult population (n=448) previously diagnosed with gingivitis and/ or periodontitis, the tooth loss rate and its potential associated factors such as diabetes, smoking, bruxism, cardiovascular…
- Trial name
- NCT06578806
- Volunteers
- 448 people
- Sponsor
- Saint-Joseph University
Periodontitis
Evaluation of L-PRF as an Antibiotic Slow-release Biological Device in the Treatment of Moderate Periodontitis
This study aimed to evaluate the efficacy of leukocyte platelet-rich fibrin (L-PRF) as a local sustained released device for antibiotics.
- Trial name
- NCT06153706
- Testing
- Subgingival application of L-PRF loaded with metronidazole, Subgingival application of L-PRF
- Where
- Egypt
- Volunteers
- 24 people
- Sponsor
- Yasmeen Khaled
Chronic Periodontitis, Intensive Care Unit
Chronic Periodontitis in Critically Ill Patients: Diagnosis and Epidemiology
This study evaluates the diagnostic performances of Point of Care P. gingivalis test in saliva with serum IgG P. gingivalis, in reference to dental examination as a gold standard in patients hospitalised in intensive care unit…
- Trial name
- CP-ICU (NCT02672384)
- Testing
- Dental examination and a point of care P. gingivalis test (Denka Seiken Co (Japan) )
- Where
- France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Brest
Diabetes, Periodontitis
Hyperbaric Oxygen Therapy as Adjunctive Therapy to Scaling and Root-planing in the Management of Periodontitis in Patients With Type 2 Diabetes
Diabetes and Periodontitis are both prevalent diseases affecting millions of Americans. Periodontitis is prevalent among Diabetics.
- Trial name
- NCT02671136
- Testing
- Hyperbaric Oxygen therapy, Conventional Wound Therapies
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Loma Linda University
Apical Periodontitis, Healhty
Inflammation-Related Endothelial Barrier Dysfunction in Patients With Apical Periodontitis
Inflammation is a common factor in chronic periodontitis and systemic diseases. However, to date, there is no scientific evidence supporting a causal effect of inflammation caused by apical periodontitis on endothelial barrier…
- Trial name
- NCT07292363
- Testing
- Apical lesions cure
- Where
- 2 sites in Italy
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Turin, Italy
Chronic Periodontitis
Influence of Stress on Non Surgical Periodontal Treatment
Treatment of periodontal diseases is influenced by several risk factors. Psychological stress is considered as one of them. Aim of this study is to assess if stress influences results of non surgical periodontal treatment in…
- Trial name
- NCT02568163
- Testing
- Non surgical periodontal treatment
- Where
- France
- Volunteers
- 72 people
- Sponsor
- University Hospital, Strasbourg, France
Periodontitis, Adult
GCF miRNA-223 , -214 Levels in Smokers and Nonsmokers Periodontitis Patients
Objective: Periodontitis is a multifactorial disease that affects a wide range of populations. However, its pathogenesis remains unclear. miRNAs are now considered potential diagnostic markers for many inflammatory diseases.
- Trial name
- NCT06064799
- Testing
- miRNA-223 & -214 detection
- Where
- Egypt
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Fayoum University
Rheumatoid Arthritis, Periodontal Diseases
Effect of Periodontal Care on Rhematoid Arthritis in Uganda
this will be an RCT. to determine if non-surgical treatment for periodontitis can improve the disease activity score in 28 joints of rheumatoid arthritis in an African setting.
- Trial name
- NCT03513263
- Testing
- Scaling and polishing, oral hygiene instructions
- Where
- Uganda
- Volunteers
- 152 people
- Sponsor
- Makerere University
Periapical Periodontitis
Comparison of Frequency of Calcium Hydroxide Mixed With 0.2% Chlorhexidine Versus Saline as Intracanal Medicament in Periapical Periodontitis-A Randomized Controlled Trial
This randomized controlled trial aims to compare the effectiveness of calcium hydroxide mixed with 0.2% chlorhexidine digluconate versus calcium hydroxide mixed with saline as intracanal medicaments in reducing postoperative pain…
- Trial name
- NCT07252258
- Testing
- Calcium Hydroxide + Normal Saline, Calcium Hydroxide + 0.2% Chlorhexidine Digluconate
- Where
- Pakistan
- Volunteers
- 80 people
- Sponsor
- Aqsa Afzal
Periodontitis
Periodontal Osseous Wall Piezosplitting and EDTA Root Surface Etching
This study was designed to investigate the use of minimally invasive Piezo knife to harvest vascularized interceptal bone pedicle in treating intrabony defects.
- Trial name
- NCT03670979
- Testing
- bone swaging
- Volunteers
- 16 people
- Sponsor
- Al-Azhar University
Periodontal Diseases, Hypersensitivity Dentin
Clinical Efficacy of Vector Paro With Hydroxyapatite in the Supportive Therapy of Periodontitis
Enamel is the most calcified tissue in the body and is composed of 92-96% by organic substances in particular hydroxyapatite. Hydroxyapatite nanoparticles are similar to the morphology and structure of tooth enamel apatite…
- Conditions
- Periodontal Diseases, Hypersensitivity Dentin, Hydroxyapatite
- Trial name
- PAROXY (NCT07482280)
- Testing
- hydroxyapatite debridment, ultrasonic debridment
- Where
- Italy
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia
Chronic Periodontitis
Minimally-invasive Non-surgical Therapy of Intrabony Defects
This investigation aims to assess the clinical and radiographic outcomes of intrabony defects treated with minimally-invasive non-surgical therapy.
- Trial name
- NCT03741374
- Testing
- Minimally-invasive non-surgical therapy (MINST)
- Where
- 9 sites in Australia, Italy and 2 more
- Volunteers
- healthy volunteers welcome
- Sponsor
- Queen Mary University of London
Periodontal Pocket
Evaluation of 2%Bromelain Gel With 0.2%CHX Gel as Subgingival LDD Following SRP in Stage II/III and Grade B Periodontitis -A RCT
The current study is a prospective randomised study Evaluation of 2%Bromelain Gel With 0.2%Chlorhexidine Gel as Subgingival Local Drug Delivery Following Scaling and Root Planing in Stage II/III and Grade B Periodontitis
- Trial name
- NCT06505759
- Testing
- Bromelain gel, chlorhexidine gel, SRP
- Where
- India
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Krishnadevaraya College of Dental Sciences & Hospital
Apical Periodontitis
Evaluation of Different Root Canal Irrigation Techniques
This clinical study aims to evaluate the effect of different root canal irrigation techniques on postoperative pain levels and periapical healing in premolar and molar teeth diagnosed with apical periodontitis (Periapical Index…
- Trial name
- NCT07106320
- Testing
- VDW Ultra Ultrasonic Irrigation Activation, EDDY Sonic Irrigation Activation, Conventional Needle Irrigation
- Where
- Turkey (Türkiye)
- Volunteers
- 162 people
- Sponsor
- Medipol University
Chronic Periodontitis
Comparison of Rosuvastatin With Atorvastatin in Chronic Periodontitis
The present study is designed as a single-centre, randomized, controlled clinical trial to evaluate and compare the clinical and radiographic efficacy of two local drug delivery systems containing 1.2% RSV gel and 1.2% ATV gel in…
- Trial name
- NCT02600520
- Testing
- SRP with RSV gel LDD, SRP with ATV gel LDD
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Government Dental College and Research Institute, Bangalore
Periodontitis, Panoramic Radiography
Fractal and Morphometric Analysis of Mandibular Bone in Periodontitis
This retrospective study aims to evaluate the differences in mandibular bone structure between individuals with periodontitis and healthy controls using panoramic radiographs.
- Trial name
- PBFM (NCT07209579)
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Istanbul University
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