Clinical trials: Pars Plana Vitrectomy
Retinal Detachment
23-gauge Pars Plana Vitrectomy With Silicone Oil Injectionsilicone Oil Injection With Surgical
Objective: to evaluate anatomical and visual outcomes of 23-gauge vitrectomy for retinal detachment with silicone oil injection in fifty cases.
- Trial name
- NCT04280770
- Testing
- 23 PARS PLANA VITRECTOMY
- Volunteers
- 50 people
- Sponsor
- Ain Shams University
Epiretinal Membrane, Macular Pucker
EpiRetinal Membrane Peeling and Internal Limiting Membrane
To study and compare visual acuity in patients undergoing removal of the epiretinal membrane with and without the removal of the internal limiting membrane at baseline versus 6 month.
- Conditions
- Epiretinal Membrane, Macular Pucker, Internal Limiting Membrane
- Trial name
- ERMP&ILM (NCT04802265)
- Testing
- Epiretinal membrane surgery
- Where
- France
- Volunteers
- 10 people
- Sponsor
- University Hospital, Clermont-Ferrand
Epiretinal Membrane
Evolution of EIFL Following PPV
Various classification systems have been described for epiretinal membrane (ERM). One of them is a new OCT-based staging scheme based on displacement and reorganization of inner retinal layers called ectopic inner retinal layers…
- Trial name
- NCT06040216
- Testing
- optical coherence tomography
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Kocaeli University
Suprachoroidal Hemorrhage (Diagnosis), Pars Plana Vitrectomy
Suprachoroidal Hemorrhage Associated With Pars Plana Vitrectomy
To analyze the characteristics, related risk factors, and prognosis of suprachoroidal hemorrhage (SCH) associated with pars plana vitrectomy (PPV).
- Trial name
- NCT05013281
- Testing
- Suprachoroidal hemorrhage associated with pars plana vitrectomy
- Where
- China
- Volunteers
- 28 people
- Sponsor
- Beijing Tongren Hospital
Vitrectomy
The Purpose of This Study is to Evaluate the Pharmacokinetic Properties of Intravitreal Ocriplasmin Prior to Planned Primary Pars Plana Vitrectomy (PPV)
To evaluate the pharmacokinetic properties of intravitreal ocriplasmin 125 µg dose when administered at different time-points prior to planned primary pars plana vitrectomy (PPV)
- Trial name
- MIVI-10 (NCT01159665)
- Testing
- ocriplasmin
- Where
- Belgium
- Volunteers
- 38 people
- Sponsor
- ThromboGenics
Epiretinal Membrane, Macular Pucker
Perioperative Topical Nepafenac After Epiretinal Membrane Surgery
This prospective comparative study evaluates whether perioperative topical nepafenac improves early anatomical and functional recovery after pars plana vitrectomy with epiretinal membrane and internal limiting membrane peeling.
- Trial name
- NEPERM (NCT07736690)
- Testing
- Nepafenac 0.1% Ophthalmic Suspension, Pars Plana Vitrectomy With Epiretinal Membrane and Internal Limiting Membrane Peeling
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Ankara Yildirim Beyazıt University
Proliferative Diabetic Retinopathy
Intravitreal Ozurdex After Pars Plana Vitrectomy for Proliferative Diabetic Retinopathy
To evaluate if intravitreal Ozurdex can reduce the incidence of recurrent vitreous hemorrhage after primary pars plana vitrectomy (PPV) in patients with proliferative diabetic retinopathy (PDRP).
- Trial name
- NCT01478737
- Testing
- Intravitreal dexamethasone implant, Vitrectomy
- Where
- Sweden
- Volunteers
- 100 people
- Sponsor
- Anders Kvanta
Comparison of 3D Visualization and Microscope for VR Surgery
Damages From Macular Grasping During Vitrectomy Comparing Traditional and 3D Microscope
Randomized, prospective, descriptive and comparative clinical study. The comparison is between a group of patients affected by macular pucker or macular hole, whose macular peeling is performed using a traditional optical…
- Trial name
- NCT05113212
- Testing
- Macular surgery with NGENUITY surgical display system, Macular surgery with standard operating microscope
- Where
- Italy
- Volunteers
- 64 people
- Sponsor
- Anna Rita Daniele, MD
Myopic Traction Maculopathy
Predictors of Vitrectomy Outcomes in Myopic Foveoschisis
This prospective pilot study evaluates factors that predict outcomes after vitrectomy for myopic foveoschisis (MFS), a sight-threatening complication of high myopia that can lead to progressive visual loss, foveal detachment…
- Trial name
- NCT07774637
- Testing
- pars plana vitrectomy
- Where
- Singapore
- Volunteers
- 30 people
- Sponsor
- Singapore National Eye Centre
Proliferative Diabetic Retinopathy
Vitrous Analysis in Proliferative Diabetic Retinopathy
Analysis of vitreous proteins in patients undergoing pars plana vitrectomy for proliferative diabetic retinopathy
- Trial name
- NCT01478763
- Where
- Sweden
- Volunteers
- 200 people
- Sponsor
- Anders Kvanta
Myopic Traction Maculopathy, Pars Plana Vitrectomy
Vitrectomy With Internal Limiting Membrane Peeling for Myopic Traction Maculopathy
Investigate the effectiveness and safety of pars plans vitrectomy, with internal limiting membrane peeling for cases of myopic traction maculopathy
- Conditions
- Myopic Traction Maculopathy, Pars Plana Vitrectomy, Internal Limiting Membrane Peeling
- Trial name
- NCT04278079
- Testing
- Pars Plana Vitrectomy with Internal Limiting Membrane peel
- Volunteers
- 52 people
- Sponsor
- Tanta University
Retinal Detachment
REtinal Detachment Outcomes Study
Background: Few large randomized controlled trials provide strong evidence to guide surgical repair of primary rhegmatogenous retinal detachment (RRD) repair.
- Trial name
- REDOS (NCT05863312)
- Testing
- Pars plana vitrectomy, Pars plana vitrectomy with scleral buckle, Sulfur hexafluoride gas tamponade
- Where
- Canada
- Volunteers
- 560 people
- Sponsor
- CHU de Quebec-Universite Laval
Cataract
Ketorolac Levels in Vitreous and Aqueous Samples From Patients Undergoing Combined Cataract and Pars Plana Vitrectomy Surgeries With and Without Intracameral Phenylephrine 1.0% / Ketorolac 0.3%
This is a clinical trial evaluating Ketorolac levels in vitreous and aqueous humor samples from patients undergoing combined cataract and pars plana vitrectomy surgeries with and without intracameral phenylephrine 1.0% /…
- Trial name
- NCT06539637
- Testing
- OMIDRIA (*Registered Product) {10.16 mg/mL (1% w/v) of phenylephrine and 2.88 mg/mL (0.3% w/v) of ketorolac}, Ketorolac Tromethamine {TORADOL} (0.5%) - Topical Eyedrop
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- DHS Consulting
Hacular Hole Repair
The (Flip and Fix) Internal Limiting Flap Technique Versus the Classic Temporal Flap for Macular Hole Repair
Purpose To describe a novel technique of MH repair and compare it to the perfluorocarbon liquid (PFCL) assisted temporal ILM flap technique.
- Trial name
- Flip and Fix (NCT06441656)
- Testing
- Vitrectomy with ILM flap
- Where
- Egypt
- Volunteers
- 22 people
- Sponsor
- Alexandria University
Retinal Disease, Macular Retinoschisis
Pars Plana Vitrectomy Alone in the Treatment of Macular Schisis in High Myopic Eyes
High myopic schisis (HMF) has the clinical feature of separation between retinal layers. It is sometimes accompanied with foveal retinal detachment, macular lamellar hole, epiretinal membrane and vitreous retraction.
- Trial name
- NCT03586193
- Testing
- Pars plana vitrectomy
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Aier School of Ophthalmology, Central South University
Idiopathic Macular Hole, Macular Hole
Intraocular Gas Tamponade for Treatment of Large Idiopathic Macular Holes
The goal of this clinical trial is to evaluate the visual and anatomical outcomes of large (410-1000 μm) full-thickness macular holes repair surgery using perfluoropropane (15% C3F8), sulfur hexafluoride (20% SF6) gas tamponade.
- Conditions
- Idiopathic Macular Hole, Macular Hole, Macular Holes, Full Thickness Macular Hole
- Trial name
- NCT06927544
- Testing
- Pars plana vitrectomy
- Where
- Ukraine
- Volunteers
- 100 people
- Sponsor
- The Filatov Institute of Eye Diseases and Tissue Therapy
Retinal Diseases, High Myopia
Long-shaft Vitrectomy Probe in Highly Myopic Eyes
This study aimed to compare the safety and efficacy of vitrectomy probe with different shaft lengths in vitreoretinal surgery of highly myopic patients.
- Trial name
- NCT04902170
- Testing
- 25 gauge pars plana vitrectomy
- Where
- Taiwan
- Volunteers
- 86 people
- Sponsor
- National Taiwan University Hospital
Tractional Retinal Detachment Secondary to Proliferative Diabetic Retinopathy
Pre-Operative Intravitreal Bevacizumab for Tractional Retinal Detachment Secondary to Proliferative Diabetic Retinopathy
The purpose of this is study is to assess the efficacy of pre-operative intravitreal bevacizumab (IVB) (Genentech, South San Francisco CA) in improving visual acuity, reducing operative time, complications, intra-operative and…
- Trial name
- NCT01976923
- Testing
- Intravitreal bevacizumab, Small-gauge pars plana vitrectomy
- Where
- Saudi Arabia
- Volunteers
- 224 people
- Sponsor
- J. Fernando Arevalo, MD FACS
Endophthalmitis
Evaluation do Early Pars Plana Vitrectomy in Acute Endophthalmitis
Our study will evaluate the efficacy of early PPV in acute endophthalmitis and attempt to prove its greater effectiveness for combating infection when compared to eyes that received only intravitreal antibiotic therapy
- Trial name
- NCT04192994
- Testing
- Intravitreal Antibiotic Injection, Pars Plana Vitrectomy
- Where
- Brazil
- Volunteers
- 25 people
- Sponsor
- Federal University of São Paulo
Hypoxia, Pars Plana Vitrectomy
Influence of HFNO on Spontaneous Breathing Support in Patients of Different ASA Risk During Moderate Multimodal Analgo-sedation for Pars Plana Vitrectomy
Pars plana vitrectomy is minimally invasive endoscopic procedure which is usually performed in moderate analgo-sedation given by anesthesiologist combined with topical anesthesia and regional eye anesthesia (retrobulbar or…
- Conditions
- Hypoxia, Pars Plana Vitrectomy, Respiratory Complications
- Trial name
- NCT04055077
- Testing
- Low-flow nasal oxygenation (LFNO) ASA I, Low-flow nasal oxygenation (LFNO) ASA II, Low-flow nasal oxygenation (LFNO) ASA III
- Where
- Croatia
- Volunteers
- 176 people
- Sponsor
- University of Split, School of Medicine