Clinical trials: Pars Plana Vitrectomy
Glaucoma
Anterior Segment Changes After Pars Plana Vitrectomy With SO Using AS-OCT
To evaluate changes in ACA induced by pars plana vitrectomy with SO 1000cs injection in vitreo-retinal surgery in phakic eyes using AS-OCT and changes in the IOP preoperatively, post-operatively and post-silicone oil evacuation.
- Trial name
- NCT06524661
- Testing
- AS-OCT after vitrectomy
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Minia University
Diabetic Retinopathy, Retinal Detachment
Pars Plana Vitrectomy (PPV) Versus Preoperative Intravitreal Bevacizumab Plus PPV to Treat Diabetic Tractional Retinal Detachment (IBETRA)
The purpose of this study is to compare the amount of intraoperative intraocular bleeding during 23-gauge pars plana vitrectomy (PPV) for diabetic traction retinal detachment (TRD) with and without preoperative intravitreal…
- Trial name
- IBETRA (NCT00690768)
- Testing
- Bevacizumab, pars plana vitrectomy
- Where
- Brazil
- Volunteers
- 20 people
- Sponsor
- University of Sao Paulo
Muscle Relaxation
Comparison of Intubation and Laryngeal Mask for Pars Plana Vitrectomy
Pars plana vitrectomy is usually performed under general anesthesia including endotracheal intubation and muscle relaxation. However, for short procedures anesthesia using a laryngeal mask without muscle relaxation is also common…
- Trial name
- ITNLMAPPV (NCT02778932)
- Where
- Germany
- Volunteers
- 148 people
- Sponsor
- University Hospital Schleswig-Holstein
Retinal Detachment
Evaluation of Visual Functions After Pars Plana Vitrectomy With and Without Internal Limiting Membrane Peeling in RRD
Internal limiting membrane peeling is performed during vitrectomy for macular diseases such as macular holes, macular edema due to diabetic retinopathy and retinal vein occlusion.
- Trial name
- NCT04139811
- Testing
- Pars Plana Vitrectomy
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Minia University
Glaucoma, Macular Pucker
Prospective Retinal and Optic Nerve Vitrectomy Evaluation (PROVE) Study
Since the introduction of vitrectomy in 1971, this procedure has become the third most frequently performed ophthalmic surgery. Approximately 225,000 vitrectomies are performed annually in the United States and indications…
- Conditions
- Glaucoma, Macular Pucker, Macula Hole, Vitreomacular Traction
- Trial name
- PROVE (NCT01162356)
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University
Macular Edema
Prophylactic Ketorolac Post Epiretinal Membrane Surgery
Evaluate the efficacy of ketorolac 0.5%, a topical non-steroidal anti-inflammatory drug (NSAID), to prevent macular edema after epiretinal membrane surgery.
- Trial name
- NCT00974753
- Testing
- Ketorolac 0.5%, Saline drops
- Where
- Canada
- Volunteers
- 18 people
- Sponsor
- Queen's University
Acute Retinal Necrosis
The Necessity and Optimal Time for Performing Pars Plana Vitrectomy in Acute Retinal Necrosis Patients
The records of patients who were diagnosed with ARN between April 2010 and February 2017 were analyzed.A retrospective review of the treatment options and outcomes of the these patients was performed.
- Trial name
- NCT03260049
- Testing
- pars plana vitrectomy
- Volunteers
- 30 people
- Sponsor
- Chongqing Medical University
Diabetic Macular Edema, Pars Plana Vitrectomy
Microinvasive Pars Plana Vitrectomy Combined ILM Peeling Versus Anti-VEGF Intravitreal Injection for Treatment-naïve Diabetic Macular Edema
Diabetic macular edema (DME) is the main cause of vision loss in patients with diabetes. At present, anti-vascular endothelial growth factor (VEGF) intravitreal injection is the first-line therapy for DME, nevertheless, some…
- Conditions
- Diabetic Macular Edema, Pars Plana Vitrectomy, Conbercept
- Trial name
- NCT05728476
- Testing
- Vitrectomy combined with ILM peeling, Conbercept intravitreal injection
- Where
- China
- Volunteers
- 102 people
- Sponsor
- Tianjin Medical University Eye Hospital
Corneal Diseases
Effect of Systemic Oxygen on Corneal Epithelial Wound Healing in Diabetic Patients Undergoing Pars Plana Vitrectomy
1. To compare the corneal epithelial defect healing time between diabetic patients receiving and not receiving supplementary oxygen after vitrectomy. 2.
- Trial name
- NCT02344732
- Testing
- Dexamethasone 0.1%, Neomycin Sulfate and Polymyxin B Sulfate topical eye drops four times daily, Homatropine 2% eye drops thrice daily, Oxygen gas
- Volunteers
- 32 people
- Sponsor
- Universiti Sains Malaysia
Vitrectomy, Retinal Detachment
Pars Plana Vitrectomy With 25-gauge 20000 Cpm, Bevel-tip Cutter
Report efficiency and clinical outcomes using 25-gauge, bevel-tip, 20000 cut per minute vitrectomy probe among eyes with various vitreo-retinal diseases
- Conditions
- Vitrectomy, Retinal Detachment, Vitreous Hemorrhage, Macular Holes
- Trial name
- HYPE (NCT04404296)
- Testing
- 25-gauge, bevel-tip, 20000 cut per minute pars plana vitrectomy
- Where
- Philippines
- Volunteers
- 50 people
- Sponsor
- Peregrine Eye and Laser Institute
Optic Disc Structural Anomaly, Maculopathy
Surgical Management of Optic Disc Pit Maculaopathy
To evaluate the anatomical and functional results of pars plana vitrectomy (PPV) combined with internal limiting membrane (ILM) peeling, endolaser photocoagulation and gas tamponade in management of optic disc pit (ODP)…
- Trial name
- NCT03185936
- Testing
- pars plana vitrectomy with internal limiting membrane (ILM) peeling
- Volunteers
- 9 people
- Sponsor
- Minia University
Vitreous Disorder, Vitreous Anomalies
Vitreous Fragments Length After Pars Plana Vitrectomy
To measure vitreous collagen fragments length after pars plana vitrectomy performed at different cut rates
- Trial name
- NCT04570007
- Testing
- Pars Plana Vitrectomy
- Where
- Italy
- Volunteers
- 25 people
- Sponsor
- Ospedale Policlinico San Martino
Retinal Detachment
Spring Loaded Syringe for Active Silicon Oil Extraction
The aim of our study is to compare between two techniques used for active SOR. The outcomes include efficiency and safety. Patients with silicon filled eyes and prepared for SOR 540 eyes of 505 patients (one eye in 470 patients…
- Trial name
- NCT07363889
- Testing
- Vitrectomy machine, Spring loaded syringe
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Sohag University
Vitreous Hemorrhage Secondary to PDR
Adjuvant Intravitreal Bevacizumab in Pars Plana Vitrectomy for Vitreous Hemorrhage
The purpose of this study is to determine the effect of pre and intra-operative bevacizumab injection on postoperative vitreous hemorrhage after diabetic vitrectomy in comparison to vitrectomy without bevacizumab injection.
- Trial name
- NCT01091896
- Testing
- Bevacizumab
- Where
- Brazil
- Volunteers
- 1 people
- Sponsor
- University of Sao Paulo
ASOCT Changes After Vitrectomy and Silicone Oil Injection
Short-term Anterior Segment Changes After Pars Plana Vitrectomy (PPV) and Silicone Oil (SO) Tamponade, Anterior Segment OCT (AS-OCT) Study.
The purpose of our study is to utilize AS-OCT to analyze the anterior segment morphological changes in the early postoperative period of patients who will undergo PPV with silicone oil injection.
- Trial name
- NCT05599854
- Testing
- vitrectomy and silicone oil injection
- Volunteers
- 30 people
- Sponsor
- Assiut University