Clinical trials: Pars Plana Vitrectomy
Intravitreal Bevacizumab Injection, Pars Plana Vitrectomy
Preoperative Injection of Bevacizumab Prior to Vitreoretinal Surgery in Diabetic Tractional Retinal Detachment
Vitreoretinal surgery for epiretinal proliferation tractional retinal detachment associated with proliferative diabetic retinopathy (PDR) is often complicated by hemorrhage from fibrovascular tissue.
- Conditions
- Intravitreal Bevacizumab Injection, Pars Plana Vitrectomy, Tractional Retinal Detachment, Diabetic Retinopathy
- Trial name
- NCT00548197
- Testing
- Bevacizumab
- Where
- Iran
- Volunteers
- 40 people
- Sponsor
- Iran University of Medical Sciences
Rhegmatogenous Retinal Detachment, Toxic Effect of Silicone
The Influence of Silicone Oil on Nerve Fiber Layer Thickness After Pars Plana Vitrectomy
The aim of the study is to evaluate the influence of silicone oil on thickness of the retinal nerve fiber layer by using optical coherence tomography (OCT) in patients following pars plana vitrectomy.
- Conditions
- Rhegmatogenous Retinal Detachment, Toxic Effect of Silicone, Glaucoma Due to Silicon Oil
- Trial name
- NCT01255306
- Testing
- Optical coherence tomography, Local medical treatment of raised intraocular pressure
- Where
- Croatia
- Volunteers
- 60 people
- Sponsor
- University Hospital Sestre Milosrdnice
Diabetic Macular Edema
Safety and Effectiveness of Ozurdex Steroid Implants for DME After Vitrectomy Surgery
Currently medications injected intravitreally in previously vitrectomized eyes have a very short half-life due to enhanced clearance of the drug.
- Trial name
- NCT01788475
- Testing
- Dexamethasone
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Lahey Clinic
Macular Hole, Retinal Detachment
Effect of Topical Aqueous Suppressants on Intraocular Gas Duration Following Pars Plana Vitrectomy
The purpose of this study is to see if glaucoma eye drops (dorzolamide-timolol) have any effect on the duration of an intraocular gas bubble following pars plana vitrectomy.
- Trial name
- NCT01257698
- Testing
- Dorzolamide 2%-timolol 0.5% topical eyedrops
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- Mid Atlantic Retina
Vitrectomy
Observational Study of Ocular Inflammation in Patients Undergoing a Pars Plana Vitrectomy
This study will evaluate the degree of post-operative ocular inflammation in patients who are undergoing a pars plana vitrectomy.
- Trial name
- NCT01319318
- Testing
- Pars Plana Vitrectomy
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Allergan
Vitrectomy
Pharmacokinetics of the Brimonidine Tartrate Posterior Segment Delivery System in Patients Undergoing Pars Plana Vitrectomy
This study will evaluate the pharmacokinetics of brimonidine following a single intravitreal administration of the 200 ug or 400 ug Brimonidine Tartrate Posterior Segment Drug Delivery System in patients 2, 4 or 8 weeks prior to…
- Trial name
- NCT01229410
- Testing
- 400 µg Brimonidine Tartrate Implant, 200 µg Brimonidine Tartrate Implant
- Where
- 2 sites in United States, Czechia
- Volunteers
- 24 people
- Sponsor
- Allergan
Diabetic Macular Edema, Epiretinal Membrane
Ozurdex for Diabetic Macular Edema Treated With Pars Plana vitrEctomy and Membrane RemovAl (OPERA Study)
This study will examine the use of the dexamethasone implant (Ozurdex) in patients with macular edema associated with an epiretinal or preretinal membrane requiring surgical intervention.
- Trial name
- OPERA (NCT01613716)
- Testing
- Ozurdex
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- The Cleveland Clinic
Vitrectomy
The Purpose of This Study is to Evaluate the Pharmacokinetic Properties of Intravitreal Ocriplasmin Prior to Planned Primary Pars Plana Vitrectomy (PPV)
To evaluate the pharmacokinetic properties of intravitreal ocriplasmin 125 µg dose when administered at different time-points prior to planned primary pars plana vitrectomy (PPV)
- Trial name
- MIVI-10 (NCT01159665)
- Testing
- ocriplasmin
- Where
- Belgium
- Volunteers
- 38 people
- Sponsor
- ThromboGenics
Muscle Relaxation
Comparison of Intubation and Laryngeal Mask for Pars Plana Vitrectomy
Pars plana vitrectomy is usually performed under general anesthesia including endotracheal intubation and muscle relaxation. However, for short procedures anesthesia using a laryngeal mask without muscle relaxation is also common…
- Trial name
- ITNLMAPPV (NCT02778932)
- Where
- Germany
- Volunteers
- 148 people
- Sponsor
- University Hospital Schleswig-Holstein