Clinical trials: Pars Plana Vitrectomy, active
Myopic Traction Maculopathy
Predictors of Vitrectomy Outcomes in Myopic Foveoschisis
This prospective pilot study evaluates factors that predict outcomes after vitrectomy for myopic foveoschisis (MFS), a sight-threatening complication of high myopia that can lead to progressive visual loss, foveal detachment…
- Trial name
- NCT07774637
- Testing
- pars plana vitrectomy
- Where
- Singapore
- Volunteers
- 30 people
- Sponsor
- Singapore National Eye Centre
Diabetes Mellitus
Fovea Sparing ILM Peeling in Diabetic Patients
The goal of this clinical trial is to compare between foveal sparing ILM peeling and total ILM peeling in diabetic patients (both type 1 and II) with proliferative diabetic retinopathy (PDR) indicated for pars plana vitrectomy…
- Trial name
- NCT07271719
- Testing
- Pars plana vitrectomy (PPV) with fovea sparing ILM peeling., PPV with total ILM peeling
- Where
- Egypt
- Volunteers
- 48 people
- Sponsor
- David Nashaat Shafik Fahmy
Ocular Trauma
The Innovative Appliance of Cohesive Viscoelastic During Pars Plana Vitrectomy in Complicated Ocular Trauma
Viscoelastic is a powerful tool in pars plana vitrectomy(PPV) surgery relative to perfluorocarbon liquid because it has the properties to dilate and engorge the retina and restore the detached retina to its original position.
- Trial name
- NCT07038668
- Testing
- Using of viscoelastic during the operation, No using of viscoelastic during the operation
- Volunteers
- 420 people
- Sponsor
- Zhongshan Ophthalmic Center, Sun Yat-sen University
Epiretinal Membrane, Macular Edema (ME)
Minimal Vitrectomy Surgery for Epiretinal Membrane
This multicenter randomized controlled trial evaluates Minimal Vitrectomy Surgery (MVS) versus conventional vitrectomy for idiopathic epiretinal membrane (ERM).
- Conditions
- Epiretinal Membrane, Macular Edema (ME), Nuclear Cataract
- Trial name
- MVS-ERM (NCT07019896)
- Testing
- Minimal Vitrectomy Surgery, Conventional Vitrectomy
- Where
- China
- Volunteers
- 140 people
- Sponsor
- Peking Union Medical College Hospital
Proliferative Diabetic Retinopathy, Diabetic Retinopathy
Continuous Delivery of Ranibizumab Via the Port Delivery System for Proliferative Diabetic Retinopathy-related Vitreous Hemorrhage With Pars Plana Vitrectomy and Limited PRP.
In prolifertive diabetic retinopathy (PDR) eyes with bleeding known as vitreous hemorrhage (VH) requiring a surgical procedure to remove the vitreous, called a vitrectomy, we will determine if the benefit and safety of adding a…
- Conditions
- Proliferative Diabetic Retinopathy, Diabetic Retinopathy, Diabetes
- Trial name
- 4 PORT (NCT07864480)
- Testing
- PDS Implant filled with 100 mg/mL Ranibizumab, Ranibizumab
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Southeast Retina Center, Georgia
Retinal Detachment Rhegmatogenous
Use of Preoperative Gas in Eyes With Macula-off Rhegmatogenous Retinal Detachment (RRD)
The purpose of this study is to evaluate whether a preoperative intraocular gas injection improves visual outcomes in patients with a macula-off rhegmatogenous retinal detachment (RRD).
- Trial name
- NCT07855770
- Testing
- Intravitreal 100% C3F8 Injection, Pars plana vitrectomy or pars plana vitrectomy with scleral buckle
- Where
- 2 sites in United States
- Volunteers
- 190 people
- Sponsor
- Wills Eye
Idiopathic Macular Hole, Macular Hole
Intraocular Gas Tamponade for Treatment of Large Idiopathic Macular Holes
The goal of this clinical trial is to evaluate the visual and anatomical outcomes of large (410-1000 μm) full-thickness macular holes repair surgery using perfluoropropane (15% C3F8), sulfur hexafluoride (20% SF6) gas tamponade.
- Conditions
- Idiopathic Macular Hole, Macular Hole, Macular Holes, Full Thickness Macular Hole
- Trial name
- NCT06927544
- Testing
- Pars plana vitrectomy
- Where
- Ukraine
- Volunteers
- 100 people
- Sponsor
- The Filatov Institute of Eye Diseases and Tissue Therapy
Central Retinal Artery Occlusion
Microneedle Intra-Arterial Injection for Retinal Artery Occlusion
This prospective interventional study evaluates the efficacy and safety of direct intra-arterial microneedle injection combined with pars plana vitrectomy for acute retinal artery occlusion (including central retinal artery…
- Trial name
- NCT07151755
- Testing
- Vitrectomy + Direct Intra-Arterial Microneedle Thrombolysis + Standard Care, Standard Clinical Care Only
- Where
- China
- Volunteers
- 24 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Retinal Detachment
Spring Loaded Syringe for Active Silicon Oil Extraction
The aim of our study is to compare between two techniques used for active SOR. The outcomes include efficiency and safety. Patients with silicon filled eyes and prepared for SOR 540 eyes of 505 patients (one eye in 470 patients…
- Trial name
- NCT07363889
- Testing
- Vitrectomy machine, Spring loaded syringe
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Sohag University
Retinal Detachment
REtinal Detachment Outcomes Study
Background: Few large randomized controlled trials provide strong evidence to guide surgical repair of primary rhegmatogenous retinal detachment (RRD) repair.
- Trial name
- REDOS (NCT05863312)
- Testing
- Pars plana vitrectomy, Pars plana vitrectomy with scleral buckle, Sulfur hexafluoride gas tamponade
- Where
- Canada
- Volunteers
- 560 people
- Sponsor
- CHU de Quebec-Universite Laval
Macular Holes
Full-Thickness Macular Hole Surgery: A Comparison of Ten Techniques
This study compares ten modern vitreoretinal surgical techniques for full-thickness macular hole repair. Participants will be randomly assigned to one of the surgical approaches during pars plana vitrectomy, using stratified…
- Trial name
- FTMH-10 (NCT07606404)
- Testing
- Pars Plana Vitrectomy (PPV)-Based Macular Hole Surgery, Autologous Platelet-Rich Plasma (PRP), Human Amniotic Membrane (hAM) Graft
- Where
- Kazakhstan
- Volunteers
- 120 people
- Sponsor
- Kazakh Eye Research Institute
Pars Plana Vitrectomy
INTRAOCULAR PRESSURE MEASUREMENT AT the END of PARS PLANA VITRECTOMY
Intraocular pressure is measured regularly at any and all visits with your eye doctor or optometrist. The purpose of this study is to compare measurements of eye pressure at the end of the surgery, comparing the ability of a…
- Trial name
- NCT06707168
- Testing
- Digital palpation, Cotton-tipped applicator (CTA)
- Volunteers
- 30 people
- Sponsor
- Sunnybrook Health Sciences Centre
Macular Hole
Outcomes of Macular Hole Surgery With Inverted Flap With vs Without Post op Posturing With SF6 in Macular Hole More Than 400 Micrometres
This study evaluated the outcomes of surgery for large full-thickness macular holes measuring more than 400 micrometres using the inverted internal limiting membrane flap technique with sulphur hexafluoride (SF6) gas tamponade.
- Trial name
- NCT07787390
- Testing
- Macular Hole Surgery With Inverted Internal Limiting Membrane Flap and SF6 Gas Tamponade, Face-Down Postoperative Positioning, No Face-Down Postoperative Positioning
- Where
- Pakistan
- Volunteers
- 52 people
- Sponsor
- Lahore General Hospital
Retinal Displacement After Retinal Detachment Surgery
Influence of Perfluorocarbon Liquid (LIQUID) During Pars Plana Vitrectomy on Retinal Vessel Displacement in Primary Macula-involving Rhegmatogenous Retinal Detachment
Rhegmatogenous retinal detachment (RRD) is an acute, sight threatening condition, with an incidence of approximately 10 per 100,000 people.
- Trial name
- LIQUID (NCT07027098)
- Testing
- Perflurocarbon liquid, Without Perflurocarbon liquid
- Where
- United Kingdom
- Volunteers
- 292 people
- Sponsor
- Norfolk and Norwich University Hospitals NHS Foundation Trust
Rhegmatogenous Retinal Detachment With Grade C Proliferative Vitreoretinopathy
Comparison of Visual Outcomes of Pars Plana Vitrectomy With and Without Injection Clexane for Rhegmatogenous Retinal Detachment Proliferative Vitreoretinopathy
This interventional prospective study was conducted in the Department of Ophthalmology at Lahore General Hospital, Lahore. The study included 60 male and female patients aged 18-65 years who had rhegmatogenous retinal detachment…
- Trial name
- NCT07787377
- Testing
- Enoxaparin Sodium, Pars Plana Vitrectomy
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Lahore General Hospital