Clinical trials: Particulate Matter
Heart Disease
Cardiac Vulnerability in Potentially Susceptible Patients
This project is part of a program project directed toward assessing cardiac effects of particulate and other ambient air pollutants.
- Trial name
- NCT00012493
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- National Institute of Environmental Health Sciences (NIEHS)
Pulmonary Disease, Cardiac Disease
World Trade Center (WTC) CHEST
This project will evaluate the effects of World Trade Center (WTC) exposure in WTC responders 10-13 years following the events of 9/11.
- Conditions
- Pulmonary Disease, Cardiac Disease, Cardiopulmonary Disease, Obstructive Sleep Apnea
- Trial name
- NCT01466218
- Where
- United States
- Volunteers
- 1,012 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Chronic Kidney Diseases, Particulate Matter
Assessment of Health Effects of Air Purifier Interventions on Chronic Kidney Disease Patients
This exploratory study investigates the impact of indoor air quality improvement via air purifiers on the health of chronic kidney disease (CKD) patients.
- Trial name
- NCT06963372
- Where
- South Korea
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Inha University Hospital
Pollution; Exposure, Acute Coronary Syndrome
Impact of Air Pollution and Climate Changes on the Epidemiology of Cardiovascular Disease
Despite the fact that the topic of air pollution has been in focus of researchers for many years, there are no big studies that take up the matter of its influence on acute coronary, cerebral syndromes and CVD mortality in…
- Conditions
- Pollution; Exposure, Acute Coronary Syndrome, Chronic Coronary Insufficiency, Particulate Matter Inhalation Injury
- Trial name
- PL-PARTICLES (NCT04541498)
- Testing
- Impact of air pollution and climate changes
- Where
- Poland
- Volunteers
- 150,000 people
- Sponsor
- Medical University of Bialystok
Airway Inflammation
Airborne Ultrafine and Fine Particulate Matter: A Cause for Endothelial Dysfunction in Man?
The purpose of this study is to examine biological pathways of altered blood vessel function resulting from breathing airborne particulate.
- Trial name
- NCT00814281
- Testing
- Montelukast
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Marywood University
Cardiovascular Diseases, Particulate Matter Inhalation Injury
Impact of Lifetime Exposure to Air and Noise Pollution on Cardiovascular Disease and Mortality - the AIRCARD Study.
The purpose of this study is to determine the impact of individually lifetime accumulated exposure to air and noise pollution on the incidence and prevalence of cardiovascular diseases (CVD) and mortality.
- Conditions
- Cardiovascular Diseases, Particulate Matter Inhalation Injury, Arteriosclerosis, Pollution; Exposure
- Trial name
- AIRCARD (NCT04353232)
- Where
- Denmark
- Volunteers
- 33,723 people, healthy volunteers welcome
- Sponsor
- Odense University Hospital
Chronic Obstructive Pulmonary Disease
London Underground Study - Health Effects of Particulate Matter
An average of 4.8 million journeys are made on the London Underground every day and as the 'Tube' has elevated airborne particulate matter concentrations compared to ambient air, this raises concern about the potential health…
- Trial name
- NCT04614064
- Testing
- Exposure to London Underground ambient particulate matter, Exposure to London air ambient particulate matter
- Where
- United Kingdom
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Endothelial Dysfunction, Endothelial Function
Cycling, Air Pollution and Health
Introduction: Cycling is currently promoted at the municipal, provincial and national level as a form of active transportation that increases physical activity while at the same time reducing traffic congestion, traffic-related…
- Conditions
- Endothelial Dysfunction, Endothelial Function, Cardiovascular Physiological Phenomena
- Trial name
- CAPaH (NCT01708356)
- Testing
- Cycling on a residential route
- Where
- Canada
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Lung Injury, Particulate Matter Inhalation Injury
Food Intake REstriction for Health OUtcome Support and Education (FIREHOUSE) Trial
This is a randomized-controlled unblinded clinical trial to investigate dietary intervention on metabolic biomarker assessment in World Trade Center (WTC) Lung Injury (LI) in firefighters.
- Trial name
- NCT03581006
- Testing
- Low-Calorie Mediterranean Diet, Technology based monitoring and behavioral participation, Usual care group
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- NYU Langone Health
Airborne Microorganisms, Particulate Matter (PM)
Clean Air for Everyone (CLAIRE): an Intervention Study to Reduce the Amount of Fine Particulate Matter and Microorganisms in Classroom Air
In this study, the investigators tested whether portable air cleaners can improve the air quality in primary school classrooms. Poor air quality can affect children's respiratory health and learning.
- Trial name
- CLAIRE (NCT07479420)
- Testing
- HEPA filter air cleaners, Ionization or plasma air cleaners
- Where
- Netherlands
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Lidwien Smit
Air Pollution, Cardiometabolic Health
HEPA, PM2.5, and Cardiometabolic Health
The goal of this randomized, double-blind, crossover trial is to test the hypothesis that a longer-term indoor HEPA filtration intervention can improve cardiometabolic profiles by reducing indoor PM2.5 exposures in at-risk…
- Trial name
- NCT05718245
- Testing
- HEPA filter
- Where
- United States
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Cardiovascular Diseases in Old Age
Reducing PM-associated CV Health Effects for Seniors
The objective of this study is to investigate the effectiveness of air filtration at reducing personal-level exposures to fine particulate matter (PM2.5) and mitigating related cardiovascular (CV) health effects among older…
- Trial name
- NCT03334565
- Testing
- Low efficiency air filtration systems, High efficiency air filtration systems
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Michigan State University
Respiratory Conditions Due to Unspecified External Agent
Anti-pollution Effects of AP Green Tea Extracts
The objective of this clinical trial is to evaluate the anti-pollution effects of AP green tea extracts in subjects with discomforts related to the respiratory system by prolonged exposure to particulate matter in air pollution
- Trial name
- NCT04340375
- Testing
- AP green tea extracts
- Where
- South Korea
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Amorepacific Corporation
Attention Impaired, Risk-Taking
Effect of Air Pollution on the Cognitive Function of Adolescents
Previous observational studies have reported an association between higher air pollution exposure and lower attention in children.
- Conditions
- Attention Impaired, Risk-Taking, Risk Behavior, Social Preferences
- Trial name
- ATENC!Ó (NCT03762239)
- Testing
- Purifying the air with a Pure Airbox device (Zonair 3D)
- Where
- Spain
- Volunteers
- 2,123 people, healthy volunteers welcome
- Sponsor
- Barcelona Institute for Global Health
Acute Coronary Syndrome, Atrial Fibrillation
Short- and Long-term Health Effects of Air Pollution in Poland
The effects of air pollution on the frequency of hospital admissions and mortality due to acute coronary syndromes, atrial fibrillation, and renal disfunction are noted also in areas perceived as pollution-free (due to the lack…
- Conditions
- Acute Coronary Syndrome, Atrial Fibrillation, Kidney Diseases, Particulate Matter Inhalation Injury
- Trial name
- EP-PARTICLES (NCT05198492)
- Testing
- Impact of air pollution
- Where
- Poland
- Volunteers
- 8,300,000 people
- Sponsor
- Medical University of Bialystok
Asthma Attack, Lung Function
Cost Effective Air Filtration Intervention in Low-Income Housing to Reduce Asthma Morbidity
This project will investigate the effectiveness of HEPA air cleaners in reducing indoor air pollution and improving asthma morbidity in children living in East Harlem, New York City (NYC).
- Conditions
- Asthma Attack, Lung Function, Airway Inflammation
- Trial name
- NCT07116460
- Testing
- Austin Air Cleaner
- Where
- United States
- Volunteers
- 55 people
- Sponsor
- Columbia University