Clinical trials: Pathogenesis
Coronavirus Disease 2019
COVID-19 Associated Lymphopenia Pathogenesis Study in Blood
Background: COVID-19 is an acute respiratory syndrome. One symptom of COVID-19 is a reduction in the number of cells called lymphocytes in the blood. Lymphocytes are a type of white blood cell that fights infections.
- Trial name
- NCT04401436
- Where
- 3 sites in United States
- Volunteers
- 240 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Stroke, PET
The Origin and Role of Thromboembolism in the Pathogenesis of Ischaemic Stroke
Ischaemic stroke is usually due to occlusion of a cerebral artery by thrombus. However, it is often difficult to identify the source of thrombus, or to confirm thrombus as a cause of ischaemic stroke.
- Conditions
- Stroke, PET, Thrombosis
- Trial name
- TORPIS (NCT05636748)
- Testing
- 18F-GP1 PET/CT, Agitated Contrast Echocardiogram, MRI Head
- Where
- United Kingdom
- Volunteers
- 120 people
- Sponsor
- University of Edinburgh
Aortic Dissection, Family Research
Study on Susceptibility Genes and Pathogenic Mechanism of Non-syndromic Familial Aortic Dissection
Aortic dissection is dangerous and difficult to predict, so it is particularly important to carry out early prevention, diagnosis and rational treatment for high-risk groups.
- Conditions
- Aortic Dissection, Family Research, Aortic Dissection, Familial, With or Without Aortic Aneurysm
- Trial name
- NCT04439565
- Testing
- movement
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Chinese Medical Association
Multiple Sclerosis
Characteristic Study on Chinese Patients With Multiple Sclerosis
Compared with MS in white populations, in people of China descent multiple sclerosis (MS)is characterized by lower prevalence, more frequent and severe involvement of the visual system at onset and during the entire clinical…
- Trial name
- NCT00818103
- Testing
- atorvastatin, β-interferon, EPO
- Where
- China
- Volunteers
- 600 people
- Sponsor
- Sun Yat-sen University
Tinnitus, Subjective, Tinnitus
Inflammation in Tinnitus
Rationale: Tinnitus is the perception of sound without an external source. In the past decade, inflammation has been implicated in the pathophysiology of tinnitus.
- Conditions
- Tinnitus, Subjective, Tinnitus, Inflammation
- Trial name
- INFLATIN (NCT05268770)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University Medical Center Groningen