Clinical trials: Pathological Conditions, Anatomical
Gastrointestinal Cancer
A Study of Selective Internal Radiation Therapy for the Management of Chemotherapy-induced Thrombocytopenia With Splenomegaly in Adult Subjects With Gastrointestinal Cancer
This is a prospective, interventional, open-label, single-arm, multicenter pilot study evaluating the safety, tolerability and maximum tolerated dose (MTD) of splenic Selective Internal Radiation Therapy (SIRT) using TheraSphere…
- Trial name
- SPLENIC-SIRT (NCT07575854)
- Testing
- TheraSphere
- Where
- 4 sites in France
- Volunteers
- 18 people
- Sponsor
- Centre Georges Francois Leclerc
Hypercholesterolemia
Safety Study of Bile Acid to Treat Hypercholesteremia
Preclinical data support the hypothesis that the administration of AHRO-001 reduces LDL cholesterol levels, improves HDL function, and finally, decreases atheromatous plaque burden.
- Trial name
- NCT01931241
- Testing
- AHRO-001
- Where
- Russia
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- AtheroNova Inc.
Female Genital Fistula, Incontinence
Adverse Outcomes Following Female Genital Fistula Repair
Following genital fistula repair, fistula repair breakdown and recurrence, persistent and incidence incontinence are major adverse outcomes, limiting women's health and wellbeing.
- Trial name
- Mulisa (NCT05437939)
- Where
- Uganda
- Volunteers
- 802 people
- Sponsor
- University of California, San Francisco
Lumbar Disc Herniation, Radiculopathy Lumbar
Non-pharmacological Treatment and Pharmacological Treatment for Non-acute Lumbar Disc Herniation
This study is a 2-armed parallel, multi-centered, pragmatic clinical trial that compares the comparative effectiveness of non-pharmacological treatment and pharmacological treatment for non-acute lumbar disc herniation.
- Trial name
- NCT05003726
- Testing
- non-pharmacological treatment, pharmacological treatment
- Where
- 4 sites in South Korea
- Volunteers
- 36 people
- Sponsor
- Jaseng Hospital of Korean Medicine
Pancreatic Fistula
Trans-drain Occlusion for Postoperative Pancreatic Fistula- A Double Blind Randomized Clinical Trial
This is a multicenter, investigator initiated, prospective, superiority, parallel-group, randomized, double-blinded trial that aims to compare the efficacy and safety of trans-drain occlusion followed by gradual withdrawal of…
- Trial name
- NCT03800940
- Testing
- Fistulography and trans-drain occlusion, Fistulography
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- National Taiwan University Hospital
Pelvic Organ Prolapse, Prolapse
Early Feasibility Study of the Reia Vaginal Pessary
This is an early feasibility open-label non-randomized trial to obtain preliminary information about the function and effectiveness of a novel vaginal pessary for the use in women who suffer from symptoms of pelvic organ prolapse…
- Trial name
- NCT04275089
- Testing
- Reia Vaginal Pessary
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Reia, LLC
Prolapse
RCT: Impact of Preop Video on Patient Preparedness for Surgery
This is a single-blind, randomized (1:1 allocation), stratified, single-parallel clinical trial at one institution evaluating the use of a preoperative patient education video as an adjunct to preoperative counseling on…
- Trial name
- NCT02076360
- Testing
- Preoperative Video
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of South Florida
Polyp of Colon
De-implementation of Outdated Colonoscopy Surveillance Interval Recommendations Among Patients With Low-risk Adenomas
The purpose of this study is to compare the effectiveness of three standard of care outreach approaches (i.e., mailed letter, secure message, and telephone call) on patient adoption of the new 10-year colonoscopy surveillance…
- Trial name
- DESIRE (NCT05389397)
- Testing
- Outreach
- Where
- United States
- Volunteers
- 604 people, healthy volunteers welcome
- Sponsor
- Kaiser Permanente
Acne Scars - Mixed Atrophic and Hypertrophic
Topical Timolol 0.5% in Atrophic Acne Scar
The aim of the study is to evaluate the efficacy and safety of microneedling combined with topical timolol 0.5% in the treatment of atrophic acne scars.
- Trial name
- NCT05597813
- Testing
- microneedling, microneedling with topical timolol 0.5%
- Volunteers
- 30 people
- Sponsor
- Zagazig University
Diverticular Disease, Diverticulitis
Confocal Laser Endomicrospy in Colonic Diverticular Disease
Confocal laser endomicroscopy detects inflammatory markers undetectable during high definition endoscopy. The investigators aimed to evaluate the role of peridiverticular and colonic mucosa inflammation in the prediction of the…
- Conditions
- Diverticular Disease, Diverticulitis, Diverticula
- Trial name
- NCT04173182
- Testing
- Probe-based confocal laser endomicroscopy evaluation
- Where
- Ecuador
- Volunteers
- 63 people
- Sponsor
- Instituto Ecuatoriano de Enfermedades Digestivas
Generalized Visual Field Contraction or Constriction
A Study to Determine the Location of the Blind Spot and the Macula-disc Centre Distance on a Fundus Photograph
The study is aimed to develop a new reaction-time based method for examining the visual field and to study the effect of refractive error on the magnification of a fundus photograph in order to evaluate the true size of a retinal…
- Trial name
- NCT01843582
- Where
- Finland
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Turku University Hospital
Hypertrophic Cardiomyopathy
Treatment of Preclinical Hypertrophic Cardiomyopathy With Diltiazem
This is a pilot clinical trial to assess whether the administration of diltiazem may be able to decrease the development or progression of hypertrophic cardiomyopathy (HCM).
- Trial name
- NCT00319982
- Testing
- Diltiazem
- Where
- 2 sites in United States
- Volunteers
- 39 people
- Sponsor
- Brigham and Women's Hospital
Gingival Inflammation, Plaque
The Effectiveness of Brushing and Flossing Sequence on Control of Plaque and Gingival Inflammation
This study evaluates the effectiveness of brushing and flossing sequence in the control of dental plaque and gingival inflammation.
- Conditions
- Gingival Inflammation, Plaque, Gingival Bleeding, Plaque Control
- Trial name
- RCT (NCT03989427)
- Testing
- Brushing first and Flossing later (BF), Flossing first and Brushing later (FB)
- Where
- Malaysia
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Melaka Manipal Medical College
Colon Polyp
PULSed Field ablAtion of coloRectal Polyps
The goal of this observational study is to learn about the role of electroporation (the use of small electric pulses applied to tissue) in the treatment (ablation) of colorectal polyps.
- Trial name
- PULSAR (NCT06317727)
- Testing
- Irreversible Electroporation using EndoVE(Endoscopic Vacuum Electrode) and electrical pulses generated using ePORE(electroporation device)
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- King's College Hospital NHS Trust
Vocal Fold Sulcus ,Scar and Atrophy
Vocal Fold Injection by Platelet Rich Plasma
a study to asses safety and efficacy of platelet rich plasma injection in some types of vocal fold problems such as sulcus and atrophy to see the improvement in patient voice and its impact on patient quality of life with a good…
- Trial name
- NCT07350642
- Testing
- injection of platelet rich plasma, Nasofiberoscopy
- Where
- 2 sites in Egypt
- Volunteers
- 48 people
- Sponsor
- Assiut University
Ventral Hernia, Hernia
Pilot Trial of Abdominal Core Rehabilitation To Improve Outcomes After Ventral Hernia Repair
This study aims to evaluate the potential role of physical therapy in improving outcomes after ventral hernia repair.
- Conditions
- Ventral Hernia, Hernia, Herniorrhaphy, Abdominal Wall
- Trial name
- ABVENTURE-P (NCT05142618)
- Testing
- Supervised Physical Therapy, Post-operative Precautions
- Where
- United States
- Volunteers
- 138 people
- Sponsor
- Ohio State University
Aging, Sarcopenia
Assessing the Impact of Age, and a Short-term High-intensity Interval Training (HIIT) on Skeletal Muscle Mass and Mitochondrial Activity
The goal of this interventional study is to learn about the role of mitochondrial function in healthy aging, and then go on and assess the role of a home-based exercise program on the changes seen.
- Trial name
- Mi-HIIT (NCT05934760)
- Testing
- High intensity interval training (HIIT), Resistance based training (RET)
- Where
- United Kingdom
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Lumbar Disc Herniation
Post Market Non-Inferiority Study Comparing Triojection® to Discectomy for Lumbar Disc Herniation
The primary objective of this study is to compare the early clinical outcomes following non-surgical treatment with Triojection® to surgical discectomy. Early is defined as less than or equal to 6 months.
- Trial name
- NCT02525120
- Testing
- Triojection, Surgical discectomy
- Where
- 3 sites in Greece, Italy and 1 more
- Volunteers
- 49 people
- Sponsor
- Minimus Spine, Inc
Androgenetic Alopecia
Clinical Trial in Females for Female Pattern Hair Loss
This is a six month clinical trial to evaluate the effectiveness and safety in women with Female Pattern Hair Loss (FPHL), comparing a 5% minoxidil topical foam (MTF) formulation applied once a day versus a topical foam vehicle…
- Trial name
- NCT01226459
- Testing
- 5% Minoxidil Topical Foam, Vehicle Topical Foam
- Where
- 17 sites in United States, France and 2 more
- Volunteers
- 404 people
- Sponsor
- Johnson & Johnson Healthcare Products Division of McNEIL-PPC, Inc.
Muscle Wasting (Atrophy) After Hip Fracture Surgery
Study of Efficacy and Safety of Bimagrumab in Patients After Hip Fracture Surgery
The purpose of this study was to assess if bimagrumab is safe and effective in patients with muscle wasting (atrophy) after hip fracture surgery.
- Trial name
- NCT02152761
- Testing
- bimagrumab
- Where
- 53 sites in United States, Argentina and 17 more
- Volunteers
- 251 people
- Sponsor
- Novartis Pharmaceuticals
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.