Clinical trials: Pathological Conditions, Anatomical
Pancreatic Fistula
Prophylactic Pancreatic Stent for the Prevention of Post Operative Pancreatic Fistula
Postoperative pancreatic fistula (POPF) remains one of the most harmful complications after pancreatic resection. Some studies have indicated that endoscopic pancreatic stenting was effective in the treatment of POPF.
- Trial name
- NCT03822676
- Testing
- Prophylactic pancreatic stent
- Where
- China
- Volunteers
- 38 people
- Sponsor
- Peking Union Medical College Hospital
Stress Urinary Incontinence, Pelvic Organ Prolapse
Pelvic Floor Muscles and Success in the Surgical Treatment of Stress Urinary Incontinence and Pelvic Organ Prolapse
The aim of the study is evaluation of the efficiency of pelvic floor muscles in the context of surgical outcomes in the treatment of stress urinary incontinence and pelvic organ prolapse.
- Conditions
- Stress Urinary Incontinence, Pelvic Organ Prolapse, Pelvic Floor Disorders
- Trial name
- NCT04029168
- Where
- Poland
- Volunteers
- 140 people
- Sponsor
- Żelazna Medical Centre, LLC
End-stage Kidney Disease, End-stage Renal Disease
The Optiflow Patency and Maturation Study
The objective of this study is to assess the performance and safety of the Optiflow Anastomotic Connector (Optiflow) when used to facilitate the creation of autogenous arteriovenous fistula (AVF) anastomoses.
- Trial name
- OPEN (NCT01921933)
- Testing
- Optiflow
- Where
- United States
- Volunteers
- 51 people
- Sponsor
- Bioconnect Systems, Inc
Sarcopenia, Sleep
Exercise and the Sleep for the Sarcopenic Elderly
International data indicate that approximately 10% of the elderly will be affected by sarcopenia, a multifactorial syndrome that leads to the progressive and generalized loss of mass and muscular strength, leading to a decrease…
- Conditions
- Sarcopenia, Sleep, Physical Activity
- Trial name
- ESSE (NCT03616249)
- Testing
- Sleep, Resistance Exercise
- Where
- Brazil
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Federal University of São Paulo
Adenoma and/or Adenocarcinoma, Adenoma
Comparison of Adenoma Detection Miss Rates at Colonoscopy Associated With Different Withdrawal Times
The objective of this study is to determine the optimal withdrawal time for colonoscopy. A 6-minute withdrawal time is currently the standard of care but has only been evaluated in an observational fashion.
- Trial name
- NCT01802008
- Testing
- 3-minute withdrawal time, 6-minute withdrawal time
- Where
- 2 sites in United States
- Volunteers
- 200 people
- Sponsor
- Stanford University
Inguinal Hernia, Indirect, Children, Only
Inflammatory Stress Response in Pediatric Inguinal Hernia Repair
Today there are various surgical techniques for inguinal hernia. In this study, investigators want to compare the ''PIRS'' operating technique laparoscopy and modified "Marcy" operating technique with open inguinal access.
- Conditions
- Inguinal Hernia, Indirect, Children, Only, Inflammatory Response, Surgery
- Trial name
- NCT03203343
- Testing
- Operation - PIRS, Operation - MARCY
- Where
- Croatia
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University Hospital of Split
Arteriovenous Fistula, Arteriovenous Fistula Stenosis
Randomised Clinical Trial Comparing Drug-coated Balloon to Plain Balloon for All Peripheral AVF Stenosis
To compare the access circuit primary patency after Ranger drug-coated balloon angioplasty of arteriovenous fistula (AVF) stenosis with that after conventional balloon angioplasty
- Conditions
- Arteriovenous Fistula, Arteriovenous Fistula Stenosis, Dialysis Access Malfunction
- Trial name
- RANGER (NCT06553443)
- Testing
- Angioplasty of all peripheral AVF stenosis
- Where
- Singapore
- Volunteers
- 94 people
- Sponsor
- Singapore General Hospital
Sarcopenia, Chronic Heart Failure
Assessments of Sarcopenia Prevalence in Chronic Heart Failure Patients and in Subjects Before TAVI
The main objective was to assess the prevalence of sarcopenia in chronic heart failure patients and in patients before the trans aortic valvular implantation.
- Trial name
- PRESAR-HF (NCT03153774)
- Testing
- Assessment of sarcopenia prevalence
- Where
- France
- Volunteers
- 300 people
- Sponsor
- University Hospital, Clermont-Ferrand
Colorectal Neoplasms, Colonic Polyp
Adenoma Detection Rate Using AI System in China
The primary aim of this study is to explore the usefulness of Artificial Intelligence system in colonoscopy on adenoma detection rate (ADR). Other aims include to explore the data below when Artificial Intelligence is used.
- Conditions
- Colorectal Neoplasms, Colonic Polyp, Adenoma
- Trial name
- SinoAIADR (NCT03840590)
- Testing
- CSK AI system, Standard Colonoscopy
- Where
- 4 sites in China
- Volunteers
- 743 people, healthy volunteers welcome
- Sponsor
- Changhai Hospital
Trachea Diseases, Airway Remodeling
Feasibility of Tracheobronchial Defect Reconstruction Using Allogenic Aortic Patch
The investigators investigate the feasibility and safety of using cryopreserved aortic patches for tracheal or bronchial defect repair.
- Conditions
- Trachea Diseases, Airway Remodeling, Reconstruction Surgery
- Trial name
- NCT06935110
- Testing
- Cryopreserved aortic patch
- Where
- 2 sites in Taiwan
- Volunteers
- 10 people
- Sponsor
- National Taiwan University Hospital
Hernia, Inguinal
The Role of the Robotic Platform in Inguinal Hernia Repair Surgery
Inguinal hernia repair is one of the most commonly performed general surgery operations. However, to date, the ideal surgical approach for inguinal hernia surgery.
- Trial name
- NCT02816658
- Testing
- Laparoscopic Inguinal Hernia Repair, Robotic Inguinal Hernia Repair
- Where
- 6 sites in United States
- Volunteers
- 102 people
- Sponsor
- The Cleveland Clinic
Colon Polyp
Evaluation of the DiLumen Device During Colonoscopy
This is an observational registry study collecting data on the clinical performance of the study device (DiLumen™ ) for its intended use. The primary objective is to evaluate functional outcomes of the DiLumen device in humans.
- Trial name
- NCT03113578
- Testing
- DiLumen
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Lumendi, LLC
Lumbar Disc Herniation
Lidocaine Versus Esmolol for Optimizing Surgical Field Visibility
Intra-operative blood loss is an important attribution and predictor of the lumbar spine surgery and patient outcome. Stripping the muscle off bone makes more exposed bleeding spine surface is one of causes for blood loss during…
- Trial name
- NCT04260685
- Testing
- Lidocaine, Esmolol
- Where
- Egypt
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Breast Cancer Female, Alopecia
Hair-Safe Study: Scalp Cooling for Hair Saving in Women Undergoing Chemotherapy
Chemotherapy (CT) is a frequent and well established treatment in women with breast and gynecological tumors. Alopecia is one of the most common side effects of CT seriously impairing patient quality of life and body image.
- Trial name
- NCT04117815
- Testing
- Paxman Scalp Cooling System, Alopecia Assessments
- Where
- Austria
- Volunteers
- 128 people
- Sponsor
- Medical University Innsbruck
Hiatus Hernia
Hiatus Hernia in Old
hiatus hernia in frail patient is common and requires suregry
- Trial name
- NCT06935617
- Testing
- nissein
- Volunteers
- 266 people
- Sponsor
- Zagazig University
Healthy, Skeletal Muscle Atrophy
Evaluating Changes in Skeletal Muscle Proteins Following Resistance Exercise and Single-Leg Disuse
Skeletal muscle plays a critical role in supporting human health. Beyond its role in providing the force to move, skeletal muscle accounts for a large proportion of metabolic rate, glucose disposal, and amino acid storage.
- Conditions
- Healthy, Skeletal Muscle Atrophy, Skeletal Muscle Hypertrophy
- Trial name
- NCT06350591
- Testing
- Immobilization, Resistance training
- Where
- Canada
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Queen's University
Anatomic Stage IV Breast Cancer AJCC v8, Clinical Stage IV Cutaneous Melanoma AJCC v8
Personalized Neo-Antigen Peptide Vaccine for the Treatment of Stage IIIC-IV Melanoma, Hormone Receptor Positive HER2 Negative Metastatic Refractory Breast Cancer or Stage III-IV Non-Small Cell Lung Cancer
This phase I trial studies the safety of personalized neo-antigen peptide vaccine in treating patients with stage IIIC-IV melanoma, hormone receptor positive HER2 negative breast cancer that has spread from where it first started…
- Conditions
- Anatomic Stage IV Breast Cancer AJCC v8, Clinical Stage IV Cutaneous Melanoma AJCC v8, Locally Advanced Cutaneous Melanoma, Locally Advanced Mucosal Melanoma
- Trial name
- NCT05098210
- Testing
- Neoantigen Peptide Vaccine, Nivolumab, Poly ICLC
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- Fred Hutchinson Cancer Center
Pelvic Organ Prolapse, Urinary Incontinence
Continence After Vaginal Prolapse Surgery
Urinary incontinence after surgical correction of pelvic organ prolapse (POP) could occur. This is a condition that decreases both patients' satisfaction and quality of life.
- Trial name
- NCT05312047
- Testing
- Pelvic organ prolapse surgery
- Where
- 14 sites in Spain
- Volunteers
- 609 people
- Sponsor
- Hospital Universitari Vall d'Hebron Research Institute
Pelvic Organ Prolapse
AMBULAPSE STUDY Feasibility Study on Laparoscopic Double-mesh Sacrocolpopexy With or Without Robotic Assistance, in Female Patients Presenting With Symptomatic Pelvic Organ Prolapse, Based on an Outpatient Treatment Model.
Pelvic organ prolapse is an increasingly common functional disorder which affects approximately 30 to 40% of the female population, 12% of whom have a symptomatic form, with a psychological, physical and social impact.
- Trial name
- AMBULAPSE (NCT03764852)
- Testing
- outpatient laparoscopic
- Where
- 5 sites in France
- Volunteers
- 55 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Pelvic Organ Prolapse
Comparison of Postoperative Outcomes of Laparoscopic Lateral Suspension and V-NOTES Lateral Suspension With the Salman Ketenci Gencer Technique
Comparison of Early Postoperative Outcomes of Patients Undergoing Laparoscopic Lateral Suspension and V-NOTES Lateral Suspension with the Salman Ketenci Gencer Technique
- Trial name
- NCT06802497
- Where
- Turkey (Türkiye)
- Volunteers
- 84 people
- Sponsor
- Gaziosmanpasa Research and Education Hospital
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