Clinical trials: Pathological Conditions, Anatomical
Colon Cancer, Colon Polyp
Feasibility and Safety of Single Port Robot in Colorectal Procedures
The purpose of this study is to evaluate the safety and feasibility of using the Single Port (SP) robot (daVinci, Intuitive Surgical) to perform single port robotic colon surgery and transanal robotic surgery.
- Conditions
- Colon Cancer, Colon Polyp, Rectal Cancer, Diverticulitis
- Trial name
- NCT03700593
- Testing
- Single Port Robotic Colorectal Surgery
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Marks Colorectal Surgical Associates
Ventral Hernia
A Comparison of the Outcomes in Fortiva and Strattice Mesh
A comparison of ventral hernia repair with Strattice and Fortiva mesh.Primary The study team aims to determine the hernia recurrence rates for RTI Surgical biologic mesh (Fortiva) compared to Strattice.
- Trial name
- NCT05572021
- Testing
- Prospective Ventral Hernia Repair with Fortiva, RetroSpective Ventral Hernia Repair with Strattice
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Wake Forest University Health Sciences
Congenital Diaphragmatic Hernia
Safety and Efficacy of Fetoscopic Endoluminal Tracheal Occlusion (FETO) in Congenital Diaphragmatic Hernia (CDH)
The purpose of the study is to determine if babies with left or right-sided CDH that undergo the FETO procedure survive more often and have fewer long-term complications than babies that have similar left or right-sided CDH that…
- Trial name
- NCT07577414
- Testing
- FETO with Goldballoon Detachable Balloon (GOLDBAL2) along with the Delivery Microcatheter (BALTACCI-BDPE100)
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Dr Erin Perrone
Nasal Polyposis
Nasality Evolution in a Nasal Polyposis Context : Multiparametric Evaluation : Articulatory (Imaging), Aerodynamics, Acoustics and Perception
"Nasal polyposis is a chronic inflammation of the sinonasal mucosa which is characterized by the development of polyps in the sinonasal cavities.
- Trial name
- MultiNas (NCT05131958)
- Where
- France
- Volunteers
- 30 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Degenerative Disc Disease, Spondylolisthesis
Clinical Evaluation of GENEX® DS in Instrumented Posterolateral Fusion
The overall goal of this clinical study is to characterize the fusion rate of geneX® ds bone graft substitute in comparison to autograft, which is considered the gold standard for posterolateral fusion.
- Conditions
- Degenerative Disc Disease, Spondylolisthesis, Stenosis
- Trial name
- NCT02317185
- Testing
- genex bone graft with bone graft, autogenous bone graft
- Where
- 2 sites in United States
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Spine Wave
Incisional Hernia
Does Preoperative Physical Activity Predict Postoperative Complications After Incisional Hernia Repair ?
Patients with abdominal wall incisional hernia often have numerous comorbidities, making management complex. To date, no study has described the relationship between preoperative physical activity and the occurrence of…
- Trial name
- EVENTEST (NCT07192978)
- Where
- France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Strasbourg, France
Gastrointestinal Disease, Flatulence
Evaluation of Gastrointestinal Symptoms Following Chilean Native Beans Consumption
The oligosaccharide content (raffinose, stachyose, and verbascose) in legumes would be responsible for gastrointestinal symptoms (bloating, pain, meteorism), associated with its consumption.
- Conditions
- Gastrointestinal Disease, Flatulence, Gastrointestinal Tolerance, Distension; Bowel
- Trial name
- NCT04243187
- Testing
- Chilean Native Beans
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Natalia Jara
Carotid Stenosis, Carotid Artery Diseases
Embolic Signals Detection Study (Esds) in Candidates for Surgical Carotid Revascularisation
About 20% of strokes are caused by emboli deriving from a carotid plaque. In symptomatic patients with carotid stenosis grater than 70% the Carotid Endarterectomy (CEA) reduces stroke risk by about 75% and is generally accepted…
- Conditions
- Carotid Stenosis, Carotid Artery Diseases, Carotid Atherosclerosis, Carotid Artery Plaque
- Trial name
- NCT05134493
- Where
- Italy
- Volunteers
- 120 people
- Sponsor
- Azienda Ospedaliero-Universitaria di Modena
Inguinal Hernia
Electrocoagulation Employment During TAPP Inguinal Hernia Repair
Laparoscopic TAPP (transabdominal preperitoneal) hernia repair presents a minimally invasive surgical procedure, which tends to be a gold standard in a wide range of inguinal hernia operations.
- Trial name
- NCT03566784
- Testing
- Inguinal hernia repair
- Where
- Czechia
- Volunteers
- 100 people
- Sponsor
- University Hospital Ostrava
Nasal Polyps
Medical Polypectomy and Predictors of Response
This is the first randomized parallel group clinical trial looking at oral prednisolone induced medical nasal polypectomy followed by maintenance on topical steroid therapy in patients with nasal polyposis.
- Trial name
- NCT00788749
- Testing
- Prednisolone, fluticasone nasal drops, fluticasone nasal spray
- Where
- United Kingdom
- Volunteers
- 60 people
- Sponsor
- University of Dundee
Kidney Stone
Evaluation of Emergency Computed Tomography in Suspected Renal Colic. This is an Observational Retrospective Study Aimed to Evaluate Emergency Computed Tomography in Patients at the Emergency Department in Helsingborg, Sweden, With Suspected Acute Renal Colic.
The goal of this observational study is to learn more about diagnostics in patients with suspected acute renal colic at the emergency department.
- Trial name
- NCT06805149
- Where
- Sweden
- Volunteers
- 1,500 people
- Sponsor
- Region Skane
Cholecystitis; Gallstone, Mechanical Ventilation Pressure High
The Effect of Ventilation Modes on Cerebral Oxymetry In Operation
In laparoscopic cholecystectomy method, Insufflation of CO2 in abdominal cavity causes positioning of the diaphragm upwards, a decrease in lung's volume and its compliance, an increase in the airway resistance, mismatch between…
- Conditions
- Cholecystitis; Gallstone, Mechanical Ventilation Pressure High, Intraabdominal Hypertension
- Trial name
- NCT04723043
- Testing
- mechanical ventilation modes
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Sisli Hamidiye Etfal Training and Research Hospital
Inguinal Hernia
Elective Neurectomy During Inguinal Hernia Repair
Chronic inguinal neuralgia is one of the most important complications following inguinal hernia repair. It may even outweigh the benefit of the operation.
- Trial name
- NCT00492804
- Testing
- Lichtenstein hernia repair, Neurectomy
- Where
- Switzerland
- Volunteers
- 200 people
- Sponsor
- Cantonal Hospital of St. Gallen
Bariatric Surgery Patients
The Metabolic and Genetic Drivers of Body Composition Changes Following Weight Loss Surgery
Weight loss surgery is very good at reducing body weight but it can also cause the loss of both muscle and strength. Some patients undergoing weight loss surgery do not achieve their weight loss goals and regain the weight they…
- Trial name
- NCT07178704
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- The University of Texas Medical Branch, Galveston
Fistula-in-ano, Draining Wound
A Study Of Cryptoglandular Fistula-in-ano And Associated Non-healing Draining Wounds With Kerecis SurgiClose
The purpose of this study is to determine feasibility of Kerecis intact fish skin for healing of fistula-in-ano and associated non-healing draining wounds.
- Trial name
- NCT07098715
- Testing
- Kerecis fish skin
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Mayo Clinic
Hernia
Assess the Efficacy of Prevena Plus vs SOC to Closed Incision in Pts Undergoing CAWR and Other Laparotomy Procedures.
The goal of this study to establish the efficacy of Prevena™ Plus in preventing surgical site infection after complex abdominal wall procedures and major laparotomies as compared to SOC dressing.
- Trial name
- NCT04539015
- Testing
- Prevena Plus
- Where
- United States
- Volunteers
- 170 people
- Sponsor
- New York Medical College
Hernia, Hiatal, Laparoscopic
Laparoscopic Primary Diaphragm Versus Mesh Repair for Hiatus Hernia: a Long-Term Follow-Up
Assessment of the recurrence of hiatal hernia five to ten years after repair using sutures versus sutures reinforced with non-absorbable mesh.
- Conditions
- Hernia, Hiatal, Laparoscopic, Surgery, Recurrence
- Trial name
- PRIME LTFU (NCT05662735)
- Testing
- Mesh repair, Suture repair
- Volunteers
- 60 people
- Sponsor
- Rijnstate Hospital
Sarcopenia
High vs Normal Protein Diets, Resistance Exercise, Lean Mass and Strength Gains
This study evaluates the effect of different types of diets (high and normal protein) on lean and fat mass, and strength in postmenopausal women practitioners of resistance exercise.
- Trial name
- NCT03024125
- Testing
- High protein, Normal protein, Training
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Federal University of Uberlandia
Nasal Polyps
Comparison of Intraoperative Outcomes of Microdebrider-Assisted Versus Conventional Functional Endoscopic Sinus Surgery in Patients With Sinonasal Polyposis
This study compared two surgical techniques for patients with nasal polyps affecting both sides of the nose and sinuses. Nasal polyps were soft swellings that caused symptoms such as nasal blockage, nasal discharge, and reduced…
- Trial name
- NCT07907393
- Testing
- Microdebrider-Assisted Functional Endoscopic Sinus Surgery, Conventional Functional Endoscopic Sinus Surgery
- Where
- Pakistan
- Volunteers
- 56 people
- Sponsor
- Lahore General Hospital
Crohn Disease, Rectal Fistula
A Study Using Artificial Intelligence to Identify Adults With Complex Perianal Fistulas Associated With Crohn's Disease
Natural Language Processing and machine learning are examples of artificial intelligence tools. This study will check if these tools correctly identify people with Crohn's disease with complex perianal fistulas from their medical…
- Trial name
- INTUITION-CPF (NCT04844593)
- Where
- 3 sites in Spain
- Volunteers
- 32 people
- Sponsor
- Takeda
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