Clinical trials: Pathological Conditions, Anatomical
Prolapse Genital
Comparison of Single Versus Multicenter Outcomes for Pelvic Organ Prolapse Repair Using a Mesh-capturing Device
Comparison of single versus multicenter outcomes for pelvic organ prolapse repair using a mesh-capturing device (The Uphold™ Vaginal Support System for apical and vaginal wall prolapse - Boston Scientific).
- Trial name
- KIDS (NCT03077490)
- Testing
- Transvaginal mesh Uphold TM Vaginal Support System, Transvaginal mesh Uphold TM Vaginal Support System.
- Volunteers
- 319 people
- Sponsor
- Karolinska Institutet
Inguinal Hernia
Clinical Study of Self-gripping Mesh in TAPP Versus Lichtenstein Hernia Repair
The goal of this prospective study is to compare the clinical efficacy of self-gripping mesh in laparoscopic transabdominal preperitoneal versus Lichtenstein hernia repair, in order to improve the outcome of inguinal hernia…
- Trial name
- NCT06240858
- Testing
- Laparoscopic transabdominal preperitoneal hernia repair., Lichtenstein hernia repair.
- Where
- China
- Volunteers
- 130 people
- Sponsor
- Second Hospital of Jilin University
Esophageal Cancer, Nutrition Aspect of Cancer
Assessing Timing of Enteral Feeding Support in Esophageal Cancer Patients on Muscle functTion and Survival
The surgical stress of an esophagectomy causes a detrimental impact on the physiological response of the body. In this perspective, one could question whether the current feeding regimens of starting early nutritional support at…
- Conditions
- Esophageal Cancer, Nutrition Aspect of Cancer, Postoperative Complications, Muscle Weakness
- Trial name
- EFECTS (NCT03676478)
- Testing
- delayed start enteral support @ POD5
- Where
- Belgium
- Volunteers
- 239 people
- Sponsor
- University Hospital, Gasthuisberg
Post-operative Fistula
Endoscopy for Post-operative Fistula
Endoscopic treatment of early post-operative fistula in patients with underlying esophageal or gastric cancer has now become the standard of care. However, data regarding the yield of this type of treatment is lacking.
- Trial name
- FISTULENDO (NCT04446208)
- Testing
- Endoscopy
- Where
- France
- Volunteers
- 85 people
- Sponsor
- Aymeric Becq
Disk Hernisi, Visseral Manuel Terapi
The Effect of Visceral Osteopathic Manual Therapy in Lumbar Disc Herniation
This study aims to investigate the impact of adding visceral osteopathic manual therapy techniques to conservative physical therapy on the lives of individuals with lumbar disc herniation.
- Trial name
- NCT07465068
- Testing
- osteopathic manual therapy, FTR
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Istanbul Rumeli University
Incisional Hernia
Giant Ventral Incisional Hernia: Abdominal Wall Function, Respiratory Performance and Quality of Life
One of five patients undergoing open abdominal surgery develops an abdominal wall defect (incisional hernia) as a late complication. A fraction of these are "giant" hernia with a fascial defect beyond 10 cm.
- Trial name
- GIVINA (NCT02011048)
- Testing
- Endoscopic components separation
- Where
- Denmark
- Volunteers
- 36 people
- Sponsor
- Bispebjerg Hospital
Total Hip Arthroplasty
Leg Length and Quality of Life After Total Hip Arthroplasty
This study used 3D reconstructions from the EOS biplanar radiographic imaging system to perform leg length measurements before and after THA (Total hip arthroplasty) on all included THA patients from 2015 to evaluate surgeon…
- Trial name
- EOS-PTH (NCT03437343)
- Testing
- Hip arthroplasty
- Volunteers
- 185 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Gallstone, Biliary Stricture
Diagnosis and Percutaneous Treatment of Biliary Tract Diseases
This study aims to implement and optimize the treatment of bile duct diseases in participants not eligible for endoscopic treatment using the Spyglass system, a system suitable for diagnostic and therapeutic endoscopic procedures…
- Conditions
- Gallstone, Biliary Stricture, Biliary Diseases
- Trial name
- NCT06816615
- Testing
- Percutaneous cholangioscopic-assisted treatment
- Where
- Italy
- Volunteers
- 24 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Pelvic Organ Prolapse
Modified Purandare's Cervicopexy Versus Abdominal Sacral Hysteropexy
This study aims to compare safety, efficacy and complications of modified Purandare's cervicopexy with abdominal sacral hysteropexy as conservative surgery in the treatment of genital prolapse in reproductive age group patients…
- Trial name
- NCT04852991
- Testing
- Modified Purandare cervicopexy, Abdominal sacral hysteropexy
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Ain Shams Maternity Hospital
Pelvic Organ Prolapse, Vaginal Atrophy
The Effects of Local Vaginal Estrogen in Postmenopausal Women With Pelvic Organ Prolapse
The purpose of this study is to find out how long it takes the vagina to respond to hormonal vaginal cream in women with pelvic organ prolapse (bulge in the vagina).
- Trial name
- NCT00803335
- Testing
- Vaginal conjugated estrogen cream 0.5gm, Vaginal conjugated estrogen cream 1.0gm
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- TriHealth Inc.
Sarcopenia in Elderly
Evaluation of the JUICE HA® as an Anti-sarcopenia
This study plans to recruit 60 participants aged 65 years and older who have been diagnosed with sarcopenia by a physician. Participants will be randomly assigned into JUICE HA® supplement and placebo group.
- Trial name
- NCT06950125
- Testing
- JUICE HA® supplement
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- China Medical University Hospital
Metabolic Syndrome, Insulin-resistance
Metabolic and Cardiovascular Effects of Armolipid Plus in Subjects With Metabolic Syndrome
Aim of the study is to evaluate the effects of Armolipid Plus on insulin sensitivity in patients with MetS and increased LV mass.
- Conditions
- Metabolic Syndrome, Insulin-resistance, Left Ventricular Hypertrophy
- Trial name
- ARMP-11 (NCT02295176)
- Testing
- Armolipid Plus
- Where
- 3 sites in Italy
- Volunteers
- 159 people
- Sponsor
- Rottapharm
Ureteric Stone, Flexible Ureteroscopy
Flexible vs Semi-rigid URS
To compare the efficacy, safety, success rate, operative time, and cost-effectiveness of flexible ureteroscopy versus semirigid ureteroscopy in the management of upper ureteric stones smaller than 2 cm.
- Conditions
- Ureteric Stone, Flexible Ureteroscopy, Upper Urinary Tract Stones
- Trial name
- NCT07247617
- Testing
- Flexible URS, Semi-Rigid URS
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Assiut University
Gingivitis
Clinical Study Examining the Control of Plaque and Gingivitis
The objective of this six-month clinical investigation is to evaluate the efficacy of a silica-free meridol toothpaste versus Colgate Cavity Protection Toothpaste in the control of established dental plaque and gingivitis.
- Trial name
- NCT07842978
- Testing
- Silica Free Meridol, Meridol, Colgate Dental Product
- Where
- China
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- Colgate Palmolive
Alopecia, Baldness
Safety and Efficacy Study of Bimatoprost in the Treatment of Women With Female Pattern Hair Loss
This study will evaluate the safety and efficacy of 3 doses of bimatoprost solution compared with vehicle and over-the-counter (OTC) minoxidil 2% solution in women with female pattern hair loss.
- Trial name
- NCT01325350
- Testing
- bimatoprost Formulation A, bimatoprost Formulation B, bimatoprost Formulation C
- Where
- 2 sites in United States, Germany
- Volunteers
- 306 people
- Sponsor
- Allergan
Anatomic Stage IV Breast Cancer AJCC v8, Clinical Stage IV Gastroesophageal Junction Adenocarcinoma AJCC v8
Avapritinib for the Treatment of CKIT or PDGFRA Mutation-Positive Locally Advanced or Metastatic Malignant Solid Tumors
This phase II trial studies the effect of avapritinib in treating malignant solid tumors that have a genetic change (mutation) in CKIT or PDGFRA and have spread to nearby tissue or lymph nodes (locally advanced) or other places…
- Conditions
- Anatomic Stage IV Breast Cancer AJCC v8, Clinical Stage IV Gastroesophageal Junction Adenocarcinoma AJCC v8, Clinical Stage IVA Gastroesophageal Junction Adenocarcinoma AJCC v8, Clinical Stage IVB Gastroesophageal Junction Adenocarcinoma AJCC v8
- Trial name
- NCT04771520
- Testing
- Avapritinib
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- M.D. Anderson Cancer Center
Gall Stone, Common Bile Duct Calculi
Laparoendoscopic Rendezvous for Concomitant Gall Bladder Stones and Common Bile Duct Stones
Chronic calculous cholecystitis in pediatric patients leads to choledocholithiasis in about 12% of cases. These patients require removal of stones from the common bile duct.
- Conditions
- Gall Stone, Common Bile Duct Calculi, Cholecystitis, Chronic, Choledocholithiasis
- Trial name
- LERV (NCT07008170)
- Testing
- Laparoendoscopic rendezvous
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Minia University
Rectal Cancer, Rectal Neoplasms
Mri IN STaging REctal Polyp Planes
Early cancers of the rectum can be removed safely through the anus without subjecting patients to major abdominal surgery in a procedure called TEMS (transanal endoscopic microsurgery).
- Conditions
- Rectal Cancer, Rectal Neoplasms, Colonic Polyps
- Trial name
- MINSTREL (NCT02532803)
- Testing
- Novel Pelvic MRI scan assessment
- Where
- 8 sites in United Kingdom
- Volunteers
- 55 people
- Sponsor
- Royal Marsden NHS Foundation Trust
Anal Fistula
Ligation of Intersphincteric Fistula Tract Versus Rectal Advancement Flap in the Treatment of Complex Anal Fistula
Objective: Rectal advancement flap (RAF) is currently considered the gold standard in the treatment of complex anal fistula (CAF). Clinical trials are a priority given the few consistent results available with level 1 evidence.
- Trial name
- LIFTRAF-RCT (NCT05263661)
- Testing
- LIFT, FLAP
- Volunteers
- 72 people
- Sponsor
- Hospital General Universitario Reina Sofía de Murcia
Muscle Wasting, Protein Intake
Effects of Ketones on Muscle Wasting During Caloric Restriction in Lean Females
Because of these anabolic properties of ketone bodies and the fact that ketone bodies prevent muscle protein breakdown for gluconeogenesis during energetic stress, ketone bodies can be a promising strategy to prevent or treat…
- Conditions
- Muscle Wasting, Protein Intake, Ketosis, Caloric Restriction
- Trial name
- NCT04744142
- Testing
- Ketone supplementation, Increased protein intake
- Where
- Belgium
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- KU Leuven
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.