Clinical trials: Pathological Conditions, Anatomical
Hernia
Preoperative Botulinum Toxin A to Facilitate Midline Closure in Large Chronic Ventral Hernias
In patients with large hernias, chronic retraction of the lateral abdominal wall muscles, and visceral contents that are irreducible within the hernia sac, closure of the midline can be difficult or even impossible.
- Trial name
- Probhe (NCT07628205)
- Testing
- Posterior Component Separation (PCS) with TAR, Rives-Stoppa
- Where
- Italy
- Volunteers
- 44 people
- Sponsor
- Azienda Socio Sanitaria Territoriale Ovest Milanese, Ospedale di Legnano
Female Stress Incontinence, Pelvic Organ Prolapse
Collection of Long Term Patient Outcomes Data Following Implantation of AMS Surgical Devices
To monitor post-market performance through evaluation of short and long-term performance via: Efficacy Safety Patient reported outcomes
- Trial name
- CAPTURE (NCT01673360)
- Testing
- Elevate PC, Mini Arc Pro, RetroArc
- Where
- 19 sites in United States, Canada and 6 more
- Volunteers
- 401 people
- Sponsor
- ASTORA Women's Health
Inguinal Hernia, Abdominal Wall Muscles
Transversus Abdominis Plane Block and Inguinal Hernia Repair
This prospective, randomized, double blinded, placebo-controlled study is designed to evaluate the postoperative analgesic efficacy of the ultrasound-guided transversus abdominis plane block with ropivacaine 0,75 %, in patients…
- Conditions
- Inguinal Hernia, Abdominal Wall Muscles, Regional Anesthesia, Postoperative Pain
- Trial name
- NCT02030223
- Testing
- Transversus abdominis plane block
- Where
- Greece
- Volunteers
- 59 people
- Sponsor
- Papacharalampous Panagiota
Cirrhosis, Portal Hypertension
Evaluation of Minimal Hepatic Encephalopathy in Patients With Cirrhosis and Portal Hypertension
Minimal hepatic encephalopathy (MHE) is a subclinical cognitive impairment and represents the mildest type of hepatic encephalopathy (HE).
- Trial name
- Evencipor (NCT04807803)
- Testing
- Assessment of Minimal hepatic encephalopathy (MHE)
- Where
- 2 sites in France
- Volunteers
- 82 people
- Sponsor
- IHU Strasbourg
Chronic Rhinosinusitis With Nasal Polyps (CRSwNP)
Phenotyping of Type 2 Inflammation Profile by Rheology of Nasal Secretions and Tissue Quantification of Eosinophilic Polymorphonuclear Cells in the Middle Turbinate
This monocentric, interventional study (category RIPH2) aims to characterize the rheological properties of sinonasal secretions in patients with Chronic Rhinosinusitis with Nasal Polyps (CRSwNP).
- Trial name
- PheRhEos (NCT07524127)
- Testing
- Sinonasal sample collection and inflammatory assessment
- Where
- France
- Volunteers
- 60 people
- Sponsor
- University Hospital, Montpellier
Osteoporosis, Sarcopenia
The Effect of 6 Months of Local Vibration Training in Institutionalized Elderly
This randomized controlled intervention study in institutionalized elderly investigates the effect of 6 months of local vibration therapy applied on the thigh and hip on muscle strength, muscle mass, bone density, and…
- Trial name
- NCT01499186
- Testing
- Local Vibration
- Where
- Belgium
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Renal Calculi, Renal Anomaly
RIRS for Treatment of Stones in Congenital Anomalous Kidneys
The anatomic renal abnormalities like altered spatial relations with adjacent organs, abnormal calyceal orientation, and anomalous vascular patterns make the active treatment of stones in the congenitally malformed kidney a great…
- Trial name
- NCT05240170
- Testing
- RIRS, SWL
- Where
- Egypt
- Volunteers
- 160 people
- Sponsor
- Al-Azhar University
Hernia, Abdominal
Population Based Strategies for Standardized Surgical Care
Evidence-based guidelines to improve clinical care for abdominal wall hernia repair are common, but adherence is low. This proposal aims to evaluate a stakeholder informed Replicating Effective Programs (REP) using a randomized…
- Trial name
- NCT07106541
- Testing
- Replicating Effective Programs (REP), REP with facilitation (REP-PLUS)
- Where
- United States
- Volunteers
- 68 people
- Sponsor
- University of Michigan
Lumbar Disc Herniation
Trial to Show Non-inferiority / Superiority of an Endoscopic Transforaminal Discectomy to Standard Microdiscectomy
This study compares an endoscopic transforaminal surgical technique for the treatment of a herniated disc to the standard microsurgical procedure. Clinical parameters as well as health economy will be assessed.
- Trial name
- TESCORT (NCT01622413)
- Testing
- joimax TESSYS, Microdiscectomy
- Where
- 3 sites in Austria, Germany
- Sponsor
- Joimax GmbH
Labor Dystocia
Anticholinergics for Cervical Edema in Labor
The purpose of this study is to is to determine the clinical effectiveness of a single dose of intravenous (IV) medication for the prevention of labor arrest and cesarean delivery in primiparous women undergoing trial of labor.
- Trial name
- ACCEL (NCT06702670)
- Testing
- Treatment with Diphenhydramine, Usual Care
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- The University of Texas Health Science Center, Houston
Fistula in Ano, Crohn Disease
Pediatric MSC-AFP Sub-study for Crohn's Fistula
The purpose of this study is to determine the safety of using an autologous mesenchymal stromal cell (MSC) coated fistula plug in people with fistulizing Crohn's disease.
- Trial name
- NCT03449069
- Testing
- MSC-AFP
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Mayo Clinic
Hair Transplantation
Fractional CO₂ Laser Before Follicular Unit Extraction Hair Transplantation With Platelet-Rich Plasma for Secondary Cicatricial Alopecia
Secondary cicatricial alopecia is characterized by permanent hair loss due to destruction of hair follicles following trauma, burns, infection, or other causes.
- Trial name
- CO2-FUE-PRP (NCT07751523)
- Testing
- hair transplantation preceded by fractional and PRP
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Tanta University
Cancer, Sarcopenia
Personalized Cooking and Nutrition Guidance and Physical Activities Program to Reduce Muscle Loss in Advanced Cancer
People with advanced cancer often lose muscle over time. This can make them weaker, more tired, and reduce their quality of life. Many patients also struggle to eat because of changes in taste, smell, or appetite.
- Conditions
- Cancer, Sarcopenia, Muscle Mass Loss
- Trial name
- NCT07466862
- Testing
- Oncology Dietitian's Standard of Care, Personalized Culinary and Nutrition Therapy
- Where
- Israel
- Volunteers
- 200 people
- Sponsor
- Gali Perel
Unrecognized Condition
Different Surgical Techniques Used for Prolapse Repair in Elderly Patient
The investigator aimed to compare various pelvic floor repairs in female aged from 70 to 80 years old, to see which procedure in terms of treatment-related complications of SCP, VMR and NTR by comparing the operative and…
- Trial name
- NCT03445442
- Testing
- SCP, NTR, VMR
- Volunteers
- 214 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Diabetes Mellitus, Type 2, Diabetic Peripheral Neuropathy
Muscle and Bone in Patients with Diabetes Mellitus and Neuropathy
The goal of this observational study is to evaluate muscle fiber type composition in people with type 2 diabetes mellitus (T2DM) with a common complication of T2DM: diabetic peripheral neuropathy (DNP), specifically diabetic…
- Conditions
- Diabetes Mellitus, Type 2, Diabetic Peripheral Neuropathy, Sarcopenia
- Trial name
- SVT-DNP (NCT06519942)
- Testing
- Blood sampling, Electromyoneurography (EMNG), Muscle biopsy
- Where
- Belgium
- Volunteers
- 145 people, healthy volunteers welcome
- Sponsor
- University Hospital, Ghent
Bladder Stone
Impact of Concomitant TURP on Bladder Stone Surgery Outcomes
The management of bladder stones secondary to benign prostatic hyperplasia (BPH) remains controversial regarding whether transurethral resection of the prostate (TURP) should be performed concomitantly or selectively.
- Trial name
- NCT07831486
- Testing
- Transurethral Cystolitholapaxy Alone, Transurethral Resection of the Prostate (TURP)
- Where
- Egypt
- Volunteers
- 104 people
- Sponsor
- Beni-Suef University
Cholecystitis; Gallstone
Safety of Laparoscopic ChOlecystectomy Performed by Trainee Surgeons With Different CHolangiographic Techniques
Laparoscopic cholecystectomy (LC) gained popularity among general surgeons in 1990s and rapidly become one of the most commonly performed procedures in digestive surgery, with more than one million cholecystectomies being…
- Trial name
- SCOTCH (NCT04863482)
- Testing
- IOC
- Where
- Italy
- Volunteers
- 1,500 people
- Sponsor
- Università Politecnica delle Marche
Postoperative Pain, Shoulder Pain
Regional Analgesia for Anterior Cervical Disc and Fusion Surgery
Erector Spina Plane (ESP) block has been widely used in recent years, and it is also used in the control of postoperative analgesia in many types of surgery due to its proximity to the central area and its wide spread feature.
- Conditions
- Postoperative Pain, Shoulder Pain, Anesthesia, Local, Disc Herniation
- Trial name
- NCT05680142
- Testing
- superficial cervical plexus block, cervical erector spinae plane block
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Başakşehir Çam & Sakura City Hospital
Reflux Esophagitis, Hiatal Hernia
Immunologic Factors in Reflux Esophagitis and Barrett's Esophagus
By using combination of the expression of COX-2 and NOS and immunologic reaction in the esophagus with manometry of LES and cruel diaphragm and 24 hr esophageal pH monitoring to investigate the mechanisms and to make a new and…
- Trial name
- NCT00155805
- Where
- Taiwan
- Volunteers
- 90 people
- Sponsor
- National Taiwan University Hospital
End Stage Renal Disease (ESRD)
AVF Stenosis by Electronic Stethoscope
The prevalence rate of hemodialysis in Taiwan is the highest in the world, and the number of new cases of hemodialysis and the death rate are gradually increasing every year.
- Trial name
- NCT07436559
- Testing
- Detection and Prediction of the stenosis of arteriovenous fistula in hemodialysis patients by an electronic stethoscope
- Where
- Taiwan
- Volunteers
- 30 people
- Sponsor
- National Taiwan University Hospital
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.