Clinical trials: Pathological Conditions, Anatomical
Kidney Calculi
Flexible Ureteroscopy for Large Renal Stones in Children
This prospective single-arm interventional study evaluated the efficacy and safety of flexible ureteroscopy for the treatment of large renal stones measuring 2 cm or more in pediatric patients.
- Trial name
- NCT07780409
- Testing
- Flexible Ureteroscopic Stone Disintegration
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Cairo University
Colorectal Neoplasms
Third Eye Retroscope Randomized Clinical Evaluation
The Third Eye® Retroscope® is a device that can be inserted through the instrument channel of a standard colonoscope to provide an additional, retrograde (or backward) view that reveals areas behind folds and flexures in the…
- Trial name
- TERRACE (NCT01044732)
- Testing
- Third Eye Retroscope
- Where
- 9 sites in United States, Belgium and 3 more
- Volunteers
- 448 people, healthy volunteers welcome
- Sponsor
- Avantis Medical Systems
Choledocholithiasis, Choledocholithiasis With Acute Cholangitis
Spanish Registry of Quality Indicators and Adverse Events of Endoscopic Retrograde Cholangiopancreatography
Endoscopic retrograde cholangiopancreatography (ERCP) is a technique which combines endoscopic and radiological vision and allows for therapeutic procedures on pathologies of the pancreas and bile duct.
- Conditions
- Choledocholithiasis, Choledocholithiasis With Acute Cholangitis, Cholangiocarcinoma, Sclerosing Cholangitis
- Trial name
- NCT06670547
- Testing
- Endoscopic retrograde cholangiopancreatography (ERCP)
- Volunteers
- 3,000 people
- Sponsor
- Germans Trias i Pujol Hospital
Hypertrophy, Muscle Strength
Effects of Phosphatidic Acid on Strength and Hypertrophy
There are indications that phosphatidic acid (PA) supplementation is capable of enhancing gains in strength and muscle mass in response to strength training, although the literature is still incipient and controversial.
- Trial name
- NCT04277364
- Testing
- phosphatidic acid supplementation, Strength training
- Where
- Brazil
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Colon Cancer
Colon Cancer Prognosis After Radical Surgery
1. Radical surgery. It is supposed to improve prognosis of colon cancer. A surrogate measure of achievement of radical surgery is the number of lymph nodes removed with the specimen. 2. Markers.
- Trial name
- NCT00963352
- Where
- 2 sites in Norway
- Volunteers
- 300 people
- Sponsor
- Haraldsplass Deaconess Hospital
Perianal Abscess, Anal Fistula
Machine Learning-Based Risk Stratification for Fistula Formation After Perianal Abscess Drainage
This prospective cohort study investigates the influence of provider experience and drainage location on fistula formation within 6 months following perianal abscess drainage.
- Trial name
- PRISM (NCT07019532)
- Volunteers
- 450 people
- Sponsor
- Gumushane State Hospital
Thinning Hair
A Clinical Study to Evaluate the Safety, Effectiveness and In-Use Tolerability of Hair Growth and Scalp Health Serum in Subjects With Mild to Moderate Hair Thinning.
This is a Prospective, Interventional, Randomized, Double-Blind, Placebo-Controlled, Single-Centre, Clinical Study to Evaluate the Safety, Efficacy and In-Use Tolerability of Fermented Extract Hair Growth and Scalp Health Serum.
- Trial name
- NCT07195487
- Testing
- Fermented Extract Hair Growth and Scalp Health Serum
- Where
- India
- Volunteers
- 34 people
- Sponsor
- NovoBliss Research Pvt Ltd
Ventral Hernia, Incisional Hernia
A Prospective, Multi-Center Study of Phasix™ Mesh for Ventral or Incisional Hernia Repair.
Single-arm study of Phasix Mesh in High Risk patients looking at SSI and recurrence rates.
- Trial name
- NCT01961687
- Testing
- Resorbable Mesh
- Where
- 16 sites in United States
- Volunteers
- 121 people
- Sponsor
- C. R. Bard
Colo-rectal Cancer, Cancer Colon
AI-EMERGE: Development and Validation of a Multi-analyte, Blood-based Colorectal Cancer Screening Test
Freenome is using a type of artificial intelligence, called machine learning, to identify patterns of cell-free biomarkers in blood to detect cancer early.
- Conditions
- Colo-rectal Cancer, Cancer Colon, Cancer, Rectum, Neoplasms,Colorectal
- Trial name
- NCT03688906
- Where
- 30 sites in United States, Canada
- Volunteers
- 3,275 people, healthy volunteers welcome
- Sponsor
- Freenome Holdings Inc.
Sarcopenia
L1 M1 of LDCT for Low Muscle Mass Measurement
The first lumbar spine muscle index (L1 MI) on computed tomography (CT) obtained by measuring muscle surface at the first lumbar vertebrae (L1) level is an indicator of total skeletal mass in specific populations.
- Trial name
- NCT04547478
- Testing
- low dose chest CT(LDCT)
- Where
- Taiwan
- Volunteers
- 3,304 people, healthy volunteers welcome
- Sponsor
- Far Eastern Memorial Hospital
Inguinal Hernia
Effect of Suture for Mesh Fixation in Lichtenstein Hernia Repair
The investigators want to evaluate the effect of suturing the mesh versus using a self-adhesive mesh for Lichtenstein hernia repair. Effect parameters include chronic pain.
- Trial name
- Dangrip (NCT00815698)
- Testing
- suture, no suture
- Where
- 5 sites in Denmark
- Volunteers
- 334 people
- Sponsor
- Jacob Rosenberg
Therapeutic Endoscopic Ultrasound, Advanced Endoscopy
Therapeutic Endoscopic Ultrasound for Gastrointestinal Disorders: A Multicenter Registry Study
The purpose of this retrospective chart-review registry study is to evaluate the safety profile, efficacy profile and cost-effectiveness of the various therapeutic endoscopic ultrasound (EUS) procedures (for benign and malignant…
- Conditions
- Therapeutic Endoscopic Ultrasound, Advanced Endoscopy, Therapeutic Endoscopy, Interventional Endoscopy
- Trial name
- TEUS Registry (NCT05051358)
- Testing
- Therapeutic Endoscopic Ultrasound
- Where
- United States
- Volunteers
- 5,000 people
- Sponsor
- Advanced Endoscopy Research, Robert Wood Johnson Medical School Rutgers University
Kidney Stone, Nephrolithiasis
Pediatric KIDney Stone (PKIDS) Care Improvement Network
The goals of this study are to improve the ability of pediatric patients and their caregivers to select surgical treatment options for kidney stones and to enable urologists to use techniques that result in the best outcomes for…
- Trial name
- PKIDS (NCT04285658)
- Testing
- Ureteroscopy, Percutaneous Nephrolithotomy, Shock Wave Lithotripsy
- Where
- 31 sites in United States, Canada
- Volunteers
- 1,290 people
- Sponsor
- Children's Hospital of Philadelphia
Postoperative Complications
Perioperative Fluid Therapy in Patients Undergoing Pancreaticoduodenectomy
Postoperative complication rates in patients undergoing pancreaticoduodenectomy remain high although the operation techniques have developed a lot in recent years.
- Trial name
- NCT04687826
- Testing
- Goal directed fluid therapy, Liberal fluid therapy
- Volunteers
- 168 people
- Sponsor
- Helsinki University Central Hospital
Urinary Calculi
Use of Alfuzosin in Stone Treatment With ESWL
Urinary tract stones may form in the kidneys or along the ureteric tracts and when left untreated, may result in complications such as pain, bleeding, infection and obstruction.
- Trial name
- NCT00388271
- Testing
- Alfuzosin (Xatral), standard treatment
- Where
- Singapore
- Sponsor
- Singapore General Hospital
PARKINSON DISEASE (Disorder), Sarcopenia
Effects of Resistance and Aerobic Exercises on Walking and Sarcopenic Parameters in Parkinson's Disease
The aim of this study was to investigate the effects of resistance and aerobic exercises on the following outcomes in patients with sarcopenic Parkinson's disease: Timed Up and Go Test (TUG), gait speed, Short Physical…
- Trial name
- NCT07165106
- Testing
- Aerobic Exercise, Resistance Exercise, Conventional Rehabilitation
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people
- Sponsor
- Ahi Evran University Education and Research Hospital
Dilated Cardiomyopathy (DCM)
A Phase 1 AAV Gene Therapy Trial Evaluating Safety and Preliminary Efficacy of RP-A701 in Subjects With BAG3 Dilated Cardiomyopathy
This is a Phase 1, open-label, dose-escalation trial to characterize the safety, tolerability, and preliminary efficacy of RP-A701 following a single IV administration in high-risk adult patients with BAG3-DCM.
- Trial name
- NCT07137338
- Testing
- RP-A701 is a recombinant viral vector composed of an AAV serotype rh.74 (AAVrh.74) capsid encapsulating the transgene, BCL2-associated Athanogene 3 (BAG3)
- Where
- 3 sites in United States
- Volunteers
- 8 people
- Sponsor
- Rocket Pharmaceuticals Inc.
Alzheimer's Disease
Genistein as a Possible Treatment for Alzheimer's Disease.
Genistein is an isoflavone that has antioxidant and neuroprotective effects on Alzheimer's disease (AD). A few years ago our group reported that genistein increased PPARg (peroxisome proliferator activated receptor gamma) levels.
- Trial name
- GENIAL (NCT01982578)
- Testing
- Genistein
- Where
- 2 sites in Spain
- Volunteers
- 27 people
- Sponsor
- Fundación para la Investigación del Hospital Clínico de Valencia
Alzheimer Disease
Effect of Lithium and Divalproex in Alzheimer's Disease
This study will examine the effect of the drugs lithium and divalproex (Depakote) on tau proteins, a type of protein in the brain and spinal fluid that are altered in patients with Alzheimer's disease.
- Trial name
- NCT00088387
- Testing
- Divalproex, Lithium
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Heart Failure, Sarcopenia
Mechanism of Sarcopenia in Heart Failure
The aim of the study is to provide information on the interaction between socioeconomic factors, daily physical activity, nutrition and lifestyle on loss of muscle mass and muscle function in patients with heart failure.
- Conditions
- Heart Failure, Sarcopenia, Cachexia
- Trial name
- MUSCLE-CHF (NCT05063955)
- Where
- Denmark
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Aarhus University Hospital
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.