Clinical trials: Pathological Conditions, Anatomical
Hypertension; Hypertrophy, Left Ventricular
Efficacy and Safety of Valsartan in Combination With Amlodipine Compared to Losartan Plus Hydrochlorothiazide in Patients With Hypertension and Left Ventricular Hypertrophy
This study will evaluate the safety and efficacy of amlodipine plus valsartan in patients with hypertension and left ventricular hypertrophy
- Trial name
- NCT00446563
- Testing
- Valsartan, Amlodipine, Hydrochlorothiazide
- Where
- Germany
- Volunteers
- 90 people
- Sponsor
- Novartis
Open Abdomen, Fascial Closure
Vacuum Assisted Wound Closure (VAWC) and Mesh Mediated Fascial Traction
The purpose of this multicenter trial is to prospectively evaluate a novel combination of vacuum assisted wound closure (VAWC) and mesh mediated fascial traction for closure of open abdomens.
- Trial name
- NCT00494793
- Testing
- VAWC and mesh mediated fascial traction
- Where
- 5 sites in Sweden
- Volunteers
- 111 people
- Sponsor
- Skane University Hospital
Acute Myocardial Infarction, Non-ST Elevation Myocardial Infarction
Impact of Cardiac Rehabilitation Programs on Left Ventricular Remodeling After Acute Myocardial Infarction - the REHAB Trial
The aim of REHAB trial is to investigate the impact of early mobilization after AMI in reducing left ventricular remodeling, as assessed by cardiac magnetic resonance imaging.
- Conditions
- Acute Myocardial Infarction, Non-ST Elevation Myocardial Infarction, Systemic Inflammation, Ventricular Remodeling
- Trial name
- NCT04161378
- Testing
- Cardiac imaging, Laboratory analysis
- Where
- Romania
- Volunteers
- 100 people
- Sponsor
- Cardio Med Medical Center
Kidney Calculi, Nephrolithiasis
Comparison of Suction and Conventional Ureteral Access Sheaths in Kidney Stone Surgery
The goal of this observational study is to compare conventional and suction (aspiration) ureteral access sheaths used during retrograde intrarenal surgery (RIRS) in adults with kidney stones.
- Trial name
- NCT07866209
- Testing
- Conventional Ureteral Access Sheath, Suction Ureteral Access Sheath
- Where
- Turkey (Türkiye)
- Volunteers
- 160 people
- Sponsor
- Antalya Health Sciences University
İnguinal Hernia
Quality of Life Effects of Laparoscopic and Open Surgery in Inguinal Hernia Treatment
Inguinal hernia is the most common type of hernia, presenting with swelling and pain in the groin area as clinical signs of abdominal wall hernias. The gold standard treatment for symptomatic inguinal hernias is surgery.
- Trial name
- NCT06988293
- Testing
- inguinal hernia repair
- Where
- Turkey (Türkiye)
- Volunteers
- 204 people, healthy volunteers welcome
- Sponsor
- Kahramanmaras Sutcu Imam University
Physical Activity, Breast Neoplasm
The Impact of Physical Activity on the Outcome of Surgery
Over the last decades different life style factors have been established as risk factors for various diseases. The obesity pandemic displays a good example of a disease where great effort is undertaken to characterize risk…
- Conditions
- Physical Activity, Breast Neoplasm, Colorectal Neoplasm, Gall Stones
- Trial name
- NCT01707121
- Where
- 2 sites in Sweden
- Volunteers
- 450 people
- Sponsor
- Sahlgrenska University Hospital
Critical Illness, Kidney Injury
Assessment of Kidney Function and Osteomuscular Status After Critical Care
This observational study aims to assess kidney function through direct glomerular filtration rate (GFR) using iohexol clearance, compared to estimated GFR based on creatinine and cystatin C equations.
- Conditions
- Critical Illness, Kidney Injury, Muscle Loss, Bone Loss
- Trial name
- NCT04980092
- Testing
- one-year follow-up
- Where
- Belgium
- Volunteers
- 100 people
- Sponsor
- University of Liege
Plaque-type Psoriasis
Efficacy and Safety of Intravenous and Subcutaneous Secukinumab in Moderate to Severe Chronic Plaque-type Psoriasis
The study will assess the safety and efficacy of intravenous (10mg/kg) and subcutaneous (300mg) secukinumab in moderate to severe chronic plaque-type psoriasis who are partial responders to secukinumab.
- Trial name
- STATURE (NCT01412944)
- Testing
- secukinumab 150mg, secukinumab 10mg/kg i.v. regimen
- Where
- 27 sites in United States, Austria and 6 more
- Volunteers
- 43 people
- Sponsor
- Novartis Pharmaceuticals
Gallstone
The Comparative Analysis Between Motilitone and Gasmotin for the Symptom Relief in Gallstone Patients With Functional Dyspepsia
(Cause of cholelithiasis) Recently, the average age has increased, and the occurrence of gallstones has increased as the dietary life has been westernized due to the improvement of socio-economic level.
- Trial name
- NCT04350346
- Testing
- Motilitone, Gasmotin
- Where
- South Korea
- Volunteers
- 70 people
- Sponsor
- Yonsei University
Hernia
CA125 Levels and Other Inflammatory Markers in Laparoscopic Ventral Hernia Repair
The study aims to show variation in CA-125 and other inflammatory markers assumed to be a response to trauma and peritoneal inflammation in the perioperative period of laparoscopic ventral hernia repair
- Trial name
- NCT01323361
- Testing
- Laparoscopic ventral hernia repair
- Where
- 2 sites in Norway
- Volunteers
- 10 people
- Sponsor
- Oslo University Hospital
Degenerative Disc Disease, Protrusion
Stabilizing Training in Degenerative Disc Disease
This study evaluates efficacy of stabilizing training of deep core muscles in the lumbar spine in degenerative disc disease subjects, considering the progression level of degenerative disc disease: protrusion or extrusion.
- Conditions
- Degenerative Disc Disease, Protrusion, Extrusion of Migrated Disc, Hernia
- Trial name
- NCT04119466
- Testing
- Stabilizing training
- Where
- Poland
- Volunteers
- 38 people
- Sponsor
- Wroclaw University of Health and Sport Sciences
Abortion, Dilation and Evacuation
Effect of Prophylactic Tranexamic Acid on Bleeding Outcomes for Dilation and Evacuation
Prophylactic tranexamic acid has shown been shown to reduce maternal mortality from postpartum hemorrhage with no adverse effects, but has not been studied to reduce bleeding complications with dilation and evacuation (D\&E).
- Conditions
- Abortion, Dilation and Evacuation, Hemorrhage, Blood Loss
- Trial name
- NCT04651166
- Testing
- Tranexamic acid
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Hawaii
Fistula in Ano, Rectal Fistula
Laser Assisted Treatment of Fistula In Ano
Randomised Controlled Trial comparing Laser assisted closure of transsphincteric fistula to the rectal advancement flap.
- Trial name
- LATFIA (NCT05390151)
- Testing
- Laser treatment of anal fistula, RAF
- Where
- 5 sites in Belgium
- Volunteers
- 176 people, healthy volunteers welcome
- Sponsor
- University Hospital, Antwerp
Hemorrhage, Bleeding
Evaluation of Peripheral EOS for the Peripheral Embolization Treatment to Rapidly OccluDe Venous or Arterial BleEding
To collect confirmatory data in support of the safety and performance of the ArtVentive Medical Group Endoluminal Occlusion System.
- Trial name
- OCCLUDE-II (NCT02033954)
- Where
- 7 sites in Austria, Belgium and 1 more
- Volunteers
- 40 people
- Sponsor
- ArtVentive Medical Group, Inc.
Inguinal Hernia, Pain, Acute
Is it Necessary to Fix Mesh in Laparoscopic Hernia Repair
Inguinal hernias are one of the most common diseases in general surgery practice. In a multicenter study conducted in Germany, inguinal hernia repair is one of the most common operations.
- Conditions
- Inguinal Hernia, Pain, Acute, Pain, Chronic
- Trial name
- NCT05152654
- Testing
- Tacker
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Hitit University
Nephrolithotomy, Percutaneous, Kidney Stone
The Newly Reported (0-90°) Versus (0-30°) Biplanar Fluoroscopic Puncture Technique in PCNL
To analyze and compare the puncture success rate, puncture fluoroscopy time and intraoperative puncture complications of two different puncture techniques; fluoroscopic bi-planar (0-30º) versus newly reported bi-planar (0-90º)…
- Conditions
- Nephrolithotomy, Percutaneous, Kidney Stone, PCNL
- Trial name
- NCT04557722
- Testing
- 0-30° Biplanar Fluoroscopic Puncture Techniques for Percutaneous Nephrolithotomy, New 0-90° Fluoroscopic Puncture Techniques for Percutaneous Nephrolithotomy
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Menoufia University
CRS, Polyp, Nasal
The Role of Budesonide Intrapolyp Injection in CRSwNP
Chronic rhinosinusitis with nasal polyps is a common nasal comorbidity with a wide range of symptoms that might cause severe distress and disabilities for patients.
- Trial name
- NCT05474924
- Testing
- Budesonide intrapolyp injection, Budesonide nasal wash, Prednisolone tablets
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Kafrelsheikh University
Meniscus Disorder, Meniscus, Torn Tibial
Blood Flow Restriction After Meniscus Repair
The purpose of this study is to evaluate post-operative outcomes after meniscus surgery in participants undergoing blood flow restriction training as a rehabilitative adjunct compared to those with standard rehabilitation.
- Conditions
- Meniscus Disorder, Meniscus, Torn Tibial, Meniscus Lesion, Meniscus Tear, Tibial
- Trial name
- NCT04436523
- Testing
- Blood flow restriction (Delfi Personalized Tourniquet System), Standard rehabilitation
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- University of California, San Francisco
Pelvic Organ Prolapse
ACell MatriStem Pelvic Floor Matrix Versus Native Tissue Repair, Comparative Study
The primary objective of this study is to assess the safety and effectiveness of MatriStem Pelvic Floor Matrix as compared to native tissue repair for the treatment of pelvic organ prolapse.
- Trial name
- NCT02021279
- Testing
- MatriStem Pelvic Floor Matrix, native tissue repair
- Where
- 13 sites in United States
- Volunteers
- 161 people
- Sponsor
- Integra LifeSciences Corporation
Pelvic Organ Prolapse
Prolapse and Pregnancy Assessment
Pelvic organ prolapse (POP) is one of the most common indications for gynaecological surgery. In 1997, more than 225000 inpatient surgical procedures for POP were undertaken in USA (22.7 per 10000 women) at an estimated cost of…
- Trial name
- PAPA (NCT01321762)
- Where
- United Kingdom
- Volunteers
- 403 people
- Sponsor
- Croydon University Hospital
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