Clinical trials: Pathological Conditions, Anatomical
Nasal Polyps
Mint Tea for the Treatment of Nasal Polyps
The purpose of this study is to evaluate the safety and efficacy of a new treatment for nasal polyps as compared to placebo (an inactive substance). The treatment involved is mint tea high in rosmarinic acid.
- Trial name
- NCT00465543
- Testing
- Mint tea high in rosmarinic acid, Mint tea low in rosmarinic acid
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Hamilton Health Sciences Corporation
Kidney Stones
Trial Comparing Three Different Devices for Kidney Stone Removal During Percutaneous Surgery
The investigators plan to compare three different devices that are used to break up large kidney stones during surgery for removal to see if one is faster or more efficient than the others.
- Trial name
- NCT00952315
- Testing
- Cyberwand, Stonebreaker, Lithoclast Select
- Where
- 10 sites in United States, Canada
- Volunteers
- 270 people
- Sponsor
- Indiana Kidney Stone Institute
Laparoscopic, Inguinal Hernia
Mesh Fixation Versus Non Fixation in Laparoscopic Inguinal Hernioplasty
Inguinal hernia is one of the most common types of abdominal hernias. Laparoscopic hernioplasty of inguinal hernia is a good alternative to traditional open repairs even in simple unilateral primary inguinal hernia in terms of…
- Conditions
- Laparoscopic, Inguinal Hernia, Hernioplasty
- Trial name
- NCT06258317
- Testing
- fixation of conventional polypropylene mesh
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Assiut University
Gastroschisis
Early Feeds in Gastroschisis
This study aims to evaluate the feasibility of initiating early feeds in neonates with gastroschisis, a condition where infants are born with their intestines outside the body.
- Trial name
- GAIN (NCT06878950)
- Testing
- Early Feeding Protocol
- Where
- 2 sites in United States
- Volunteers
- 20 people
- Sponsor
- University of California, Davis
Congenital Diaphragmatic Hernia
De-implementing Inhaled Nitric Oxide for Congenital Diaphragmatic Hernia
The purpose of this study is to determine if de-implementation of inhaled nitric oxide (iNO) in the post-natal resuscitation/stabilization phase affects the composite outcome of extracorporeal life support (ECLS) use and/or…
- Trial name
- NCT05213676
- Testing
- Inhaled Nitric Oxide (iNO) use, De-implementation of Inhaled Nitric Oxide (iNO) use
- Where
- 19 sites in United States
- Volunteers
- 900 people
- Sponsor
- The University of Texas Health Science Center, Houston
Pelvic Organ Prolapse
PEssary Plus Physiotherapy for Pelvic Organ Prolapse (PEPPY)
1. To determine the feasibility of conducting a randomised controlled trial (RCT) of the effectiveness of a PFMT intervention in conjunction with vaginal pessary management versus vaginal pessary management alone for women with…
- Trial name
- PEPPY (NCT01136889)
- Testing
- PFMT
- Where
- 4 sites in United Kingdom
- Volunteers
- 16 people
- Sponsor
- Glasgow Caledonian University
Androgenetic Alopecia, Male Pattern Baldness
A Study to Evaluate and Compare Injections of Autologous Dermal and Epidermal Cells Into the Balding Scalp of Subjects With Hair Loss (CA-0004512)
The purpose of the study is to evaluate the ability of injections of Ji Gami(TM) or Ji Gami(TM) DO in combination with minoxidil to induce hair growth in male and female subjects with hair loss.
- Conditions
- Androgenetic Alopecia, Male Pattern Baldness, Female Pattern Baldness
- Trial name
- NCT01451125
- Testing
- Autologous cultured dermal and epidermal cells
- Where
- 4 sites in United States
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Aderans Research Institute
Ventral Hernia
Comparative Study of Biologic Mesh Versus Repair With Component Separation.
The purpose of this study is to compare open abdominal incisional hernia repair using XenMATRIX biologic mesh versus repair with their own tissue.
- Trial name
- Davol (NCT01295125)
- Testing
- XenMATRIX mesh, Open abdominal ventral hernia repair
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- University Hospitals Cleveland Medical Center
Chronic Venous Insufficiency, Peripheral Arterial Disease
Outpatient Office Based Endovascular Procedures
The results of this study will serve as a starting point for future trials concentrating on the effectiveness and clinical outcomes of the procedures performed in an office based angiosuite.
- Conditions
- Chronic Venous Insufficiency, Peripheral Arterial Disease, Dialysis Access Malfunction, Arterio-venous Fistula
- Trial name
- NCT04054440
- Where
- United States
- Volunteers
- 26,000 people
- Sponsor
- Methodist Health System
Liver Cirrhosis
Vibration Training Approach in Liver Cirrhosis
Comprehensive Investigation of the Impact of Side-Alternating Whole-Body Vibration Training on Muscle Mass and Muscle Strength in Patients with Liver Cirrhosis and Sarcopenia Simultaneous Characterization and Evaluation of…
- Trial name
- VITAL (NCT06337656)
- Testing
- Galileo WBV
- Volunteers
- 15 people
- Sponsor
- University Hospital of Cologne
Crohn Disease, Stricture; Bowel
Endoscopic Stricturotomy Versus Endoscopic Balloon Dilatation in Patients With Crohn's Disease and Symptomatic Small Bowel Stricture
Stenosis is one of the most frequent complications in patients with Crohn's disease (CD). In particular, CD patients with intestinal strictures are often faced with short bowel syndrome after repeated or extensive surgical…
- Conditions
- Crohn Disease, Stricture; Bowel, Endoscopy, Gastrointestinal
- Trial name
- DESTRESS (NCT05009212)
- Testing
- Endoscopic stricturotomy, Endoscopic balloon dilatation
- Where
- China
- Volunteers
- 96 people
- Sponsor
- Sixth Affiliated Hospital, Sun Yat-sen University
Fall, Old Age; Atrophy
Measuring the Impact of a Multimodal Intervention on Falls and Fear Falls Among People 65 Years Old, Residents at Home
Measuring the Impact of a Multimodal Intervention on Falls and Fear Falls among People 65 Years Old, Residents at Home in Boulogne city
- Trial name
- KitPA (NCT03968536)
- Testing
- fall prevention
- Where
- France
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- Gérond'if
Gastroesophageal Reflux Disease, Hiatal Hernia
Transoral Incisionless Fundoplication (TIF) Versus Sham for Treatment of Gastroesophageal Reflux Disease (GERD)
The study objective is to evaluate the relative merits, safety and effectiveness of transoral incisionless fundoplication (TIF) in proton pump inhibitor (PPI) dependent GERD patients compared with sham procedure.
- Trial name
- NCT01110811
- Testing
- Transoral Incisionless Fundoplication (TIF)
- Where
- 4 sites in Belgium, France and 1 more
- Volunteers
- 60 people
- Sponsor
- EndoGastric Solutions
Incisional Hernia, Hernia
Comparison of Mesh Fixation Techniques in Elective Laparoscopic Repair of Incisional Hernia - ReliaTack™ v ProTack™
This study is designed to examine the effects on post operative pain after the use of a fixation device to secure a mesh in the abdomen to repair a hernia of the abdominal wall.
- Conditions
- Incisional Hernia, Hernia, Abdominal Hernia
- Trial name
- TACKoMesh (NCT03434301)
- Testing
- ReliaTack™, Protack™
- Where
- United Kingdom
- Volunteers
- 63 people
- Sponsor
- Manchester University NHS Foundation Trust
Hernia, Incisional Hernia
Early Surgical Outcomes in the Use of Hybrid Mesh for Incisional Hernia Repair: Results From a Multicenter Italian Study
Background: Ventral hernia repair poses challenges for surgeons due to controversies in approach, patient selection, and mesh selection.
- Conditions
- Hernia, Incisional Hernia, Laparoscopic
- Trial name
- SHIELD (NCT06166069)
- Where
- Italy
- Volunteers
- 272 people
- Sponsor
- Azienda Sanitaria Locale Napoli 2 Nord
Hernias Inguinal Reducible, Local Anaesthesia
Comparison Between Desarda and Lichtenstein's Technique for Inguinal Hernia Repair Under Local Anaesthesia
Inguinal hernia repair is done by two methods. The conventional method uses a prosthetic mesh for strengthening the defect but has been associated with complications.
- Trial name
- NCT03512366
- Testing
- Desarda's technique, Lichtenstein's technique
- Where
- India
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- All India Institute of Medical Sciences, Bhubaneswar
Low Back Pain, Sciatica
Ultrasound-guided Lumbar Periradicular Injection: a Non Irradiating Infiltration Technique
We propose here to evaluate the precision of lumbar periradicular infiltration performed under a transverse ultrasound approach by performing a fluoroscopic control once the needle in the desired position.
- Conditions
- Low Back Pain, Sciatica, Disc, Herniated, Foraminal Hernia
- Trial name
- NCT03453775
- Testing
- Ultrasound guided periradicular lumbar infiltration, Fluoroscopy guided periradicular lumbar infiltration
- Where
- Belgium
- Volunteers
- 100 people
- Sponsor
- Université Libre de Bruxelles
Primary Hypertension
Importance of Aldosterone in the Pathogenesis of Hypertensive Heart Disease
The Renin-Angiotensin-Aldosterone-system is important in the development of cardiovascular organ damage caused by arterial hypertension.
- Trial name
- NCT00865501
- Testing
- spironolactone
- Where
- Germany
- Volunteers
- 50 people
- Sponsor
- University of Erlangen-Nürnberg Medical School
Alopecia Areata(AA)
HCW9302 (Interleukin-2 Fusion Protein) for Alopecia Areata
This is a Phase 1, open-label, multi-center, competitive enrollment, and dose-escalation study of HCW9302 in subjects with Alopecia Areata (AA)
- Trial name
- IL-2 (NCT07049328)
- Testing
- HCW9302, an IL-2 fusion protein
- Where
- 3 sites in United States
- Volunteers
- 30 people
- Sponsor
- HCW Biologics
Pelvic Floor Disorders
Pelvic Floor Function Evaluation of Singleton Primiparae After Vaginal Delivery and Cesarean Section
Objective of this longitudinal observational cohort study was to analyze incidence of pelvic floor dysfunction (PFD) symptoms, including pelvic organ prolapse (POP), urinary incontinence (UI), and fecal incontinence (FI), seven…
- Trial name
- NCT02661867
- Testing
- delivery
- Volunteers
- 865 people
- Sponsor
- Brno University Hospital
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