Clinical trials: Pathological Conditions, Signs and Symptoms
Obesity, Morbid
The Effect of Timing of Intravenous Paracetamol Administration on Post-surgical Pain
This study is designed as a population-based prospective randomized cohort study. A prospective cohort of patients admitted to laparoscopic sleeve gastrectomy due to morbid obesity
- Trial name
- NCT03221998
- Testing
- IV paracetamol, IV saline (NaCl 0.9 %)
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Soroka University Medical Center
Sedation Complication, Frailty
Advers Events in Patients Undergoing Gastrointestinal Procedural Sedation
Investigators will include in our study patients aged 60 and over who have been evaluated in the pre-anesthesia clinic for procedures such as endoscopy, colonoscopy, ERCP, PEG, EUS, and ESD, and who have received sedation by an…
- Trial name
- NCT06044298
- Testing
- procedural sedation
- Where
- Turkey (Türkiye)
- Volunteers
- 1,500 people
- Sponsor
- Uludag University
Anaphylaxis, Hypoxia
Virtual Reality-Based Simulation Versus High-Fidelity Simulation for Emergency Management Training in Medical Interns
This study is a two-arm parallel randomized controlled non-inferiority trial designed to compare the educational effectiveness of virtual reality (VR)-based simulation with high-fidelity simulation (HFS) for emergency management…
- Trial name
- NCT07584863
- Testing
- Virtual Reality-Based Emergency Simulation, High-Fidelity Simulation
- Where
- South Korea
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Hypoxia, Respiratory Failure With Hypoxia
Finger Pulse Oximeters in Hosptial Setting
Pulse oximetry is a well-established, non-invasive measurement tool used to estimate arterial oxygen saturation. The accuracy of these cheap, readily available finger pulse oximeters has not been robustly assessed in a clinical…
- Trial name
- NCT06994663
- Volunteers
- 100 people
- Sponsor
- Barts & The London NHS Trust
Traumatic Brain Injury
Long-term Recovery and Microbiota-Gut-Brain Axis Disruption After Traumatic Brain Injury
The OVERCOME-TBI project aims to collect multimodal data approximately 1-4 and 11-14 years after an earlier well-documented traumatic brain injury (TBI) and examine factors that influence disease progression in order to gain new…
- Trial name
- OVERCOME-TBI (NCT06927063)
- Testing
- blood-based protein biomarker assessments, blood-based metabolomic/lipidomic biomarker assessments, Diffusion-weighted magnetic resonance imaging (brain)
- Volunteers
- 160 people
- Sponsor
- Turku University Hospital
Radiation Pneumonitis
Prophylactic Inhaled Steroids to Reduce Radiation Pneumonitis Frequency and Severity in Lung Cancer Patients
This randomized clinical study aims to assess whether prophylactic treatment with inhaled steroids in patients with locally advanced or concomitantly treated non-small cell lung carcinoma who are candidates for combination…
- Trial name
- NCT03803787
- Testing
- Inhaled budesonide
- Where
- 2 sites in Mexico
- Volunteers
- 72 people
- Sponsor
- Instituto Nacional de Cancerologia de Mexico
Renal Insufficiency, Chronic
Effect of Hemodialysis on Upper Airways Collapsibility in Patients With Chronic Kidney Disease
Introduction: Currently, chronic kidney disease (CKD) is one of the most serious public health problems, becoming a global epidemic.
- Trial name
- NCT02390193
- Testing
- Hemodialysis
- Where
- Brazil
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Centro Universitário de Anapolis
Adhesive Capsulitis
Comparison of Low-intensity Extracorporeal Shockwave Therapy and Low-intensity Laser Effects in Adhesive Capsulitis
The aim of this study is to compare the effects of extracorporeal shock wave therapy(eswt) applied in addition to conventional physical therapy on pain, mobility, functional ability, sleep quality and activities of daily living…
- Trial name
- NCT05689593
- Testing
- Low-intensity ESWT Group, Low-intensity laser Group, Conventional Control Group
- Where
- Turkey (Türkiye)
- Volunteers
- 65 people
- Sponsor
- Ahi Evran University Education and Research Hospital
Neck Pain, Cervical Radiculopathy
Paramedian CESI vs Selective Nerve Root PRF for Lower Cervical Radicular Pain
This study aims to compare the efficacy of ultrasound-guided selective cervical nerve root pulsed radiofrequency (PRF) versus fluoroscopy-guided paramedian cervical epidural steroid administration (CESI) for the treatment of…
- Trial name
- NCT05950321
- Testing
- Paramedian cervical epidural steroid injection, Selective nerve root pulsed radiofrequency
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Diskapi Teaching and Research Hospital
Atrial Fibrillation
Safety and Efficacy Study of Amniotic Membrane Patch to Treat Postoperative Atrial Fibrillation
The purpose of this study is to to evaluate the rate of new onset postoperative atrial fibrillation in subjects receiving the amniotic membrane patch placed on the epicardial surface as compared to subjects who did not undergo…
- Trial name
- NCT02193321
- Testing
- Amniotic Membrane Patch
- Where
- United States
- Sponsor
- University of Arizona
Hearing Loss, Noise-Induced
Noise Exposure and Near-Infrared Light
The primary objective of this work is to determine the effect noise has on the auditory system (both auditory health and performance) and also the degree to which the effect of pre-noise therapy such as Near Infrared (NIR) light…
- Trial name
- NCT03834714
- Testing
- Near Infrared Light, Noise Stimulus
- Where
- 3 sites in United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- University of Miami
Low Back Pain, Musculoskeletal Pain
Soft Active Back Exosuit to Reduce Workplace Back Pain
The goal of this clinical trial is to determine if a wearable back exosuit can make it safer and easier for workers who bend, lift, and lower objects in an industrial setting.
- Conditions
- Low Back Pain, Musculoskeletal Pain, Low Back Injury
- Trial name
- NCT05802914
- Testing
- Back Exosuit
- Where
- United States
- Volunteers
- 97 people, healthy volunteers welcome
- Sponsor
- Wyss Institute at Harvard University
Cellulite
To Assess the Effectiveness of Multiple Dose, Multiple Concentrations of Qwo, for the Treatment of Mild to Moderate Cellulite.
This is a single center, off-label, multiple dose, multiple injection areas, Phase 4 study to assess the safety and efficacy of multi-dilution CCH in adult women with mild or moderate edematous fibrosclerotic panniculopathy…
- Trial name
- NCT05026216
- Testing
- Qwo
- Where
- United States
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- DMR Research, PLLC
Neck Pain
Effectiveness of Massage of the Thoracic Region in Neck Pain
Neck pain is a common disorder in industrialized countries. Manual therapy techniques have been commonly used in the treatment of this problem.
- Trial name
- NCT06256016
- Testing
- Neck pain massage, Neck and thoracic massage
- Where
- Spain
- Volunteers
- 60 people
- Sponsor
- University of Alcala
Osteoarthritis, Pain
Study of Efficacy, Safety of Fulranumab Monotherapy for OA of Hip or Knee, PAI3003
The purpose of this study is to demonstrate the efficacy, safety, and tolerability of fulranumab as Monotherapy compared with placebo in participants with signs and symptoms of osteoarthritis of the hip or knee that are not…
- Trial name
- NCT02289716
- Testing
- Fulranumab 1 mg, Fulranumab 3 mg
- Where
- 28 sites in United States, Belgium and 6 more
- Volunteers
- 41 people
- Sponsor
- Janssen Research & Development, LLC
Morton Neuroma
Is Ultrasonography Comparable to MRI for the Detection of Morton Neuroma of the Foot?
Patients with Morton neuroma of the foot will undergo either ultrasonography or MRI. The results will be compared. In case of surgery, the pathology report will be compared with the ultrasonographic or MRI findings.
- Trial name
- NCT00284414
- Testing
- Ultrasonography or MRI
- Sponsor
- University Hospital, Ghent
Low Back Pain
Low Back Pain: Unveiling the Contribution of Motor Control Adaption Using Biomechanical Modeling and Neuroimaging
This project aims to reveal the potential sensorimotor reorganization of sensory input in low back pain patients and its association with different motor control strategies in LBP.
- Trial name
- NCT03255616
- Testing
- mechanical stimulation, vibrotactile stimulation
- Where
- Switzerland
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Balgrist University Hospital
Atrial Fibrillation
Comparison of Circumferential Pulmonary Vein Isolation Alone Versus Linear Ablation in Addition to Circumferential Pulmonary Vein Isolation for Catheter Ablation in Persistent Atrial Fibrillation: Prospective Randomized Controlled Trial
The purpose of this study is to compare the clinical outcomes depending on catheter ablation strategy for persistent atrial fibrillation.
- Trial name
- NCT02721121
- Testing
- circumferential pulmonary vein isolation, Linear ablation in addiction to circumferential pulmonary vein isolation
- Where
- South Korea
- Volunteers
- 220 people
- Sponsor
- Yonsei University
Musculoskeletal Pain, Chronic Pain
N-of-1 Trials Using mHealth in Chronic Pain
Chronic musculoskeletal pain is an important problem, and treatments are often prescribed in a "trial and error" fashion. Clinicians prescribe a treatment to a patient and then wait and see if the treatment is successful.
- Trial name
- PREEMPT (NCT02116621)
- Testing
- Trialist Intervention, smartphone
- Where
- 2 sites in United States
- Volunteers
- 215 people
- Sponsor
- University of California, Davis
Shoulder Pain, Subacromial Pain Syndrome
Digitally Delivered Exercise and Education Treatment for Shoulder Pain: 3 Months Follow-up
The overall aim of this project is to describe changes in pain and perceived shoulder dysfunction in patients with subacromial shoulder pain, following 3 months of digitally delivered first-line treatment containing exercise and…
- Trial name
- NCT05402514
- Testing
- Digitally delivered exercise and education treatment Joint Academy
- Where
- Sweden
- Volunteers
- 682 people
- Sponsor
- Joint Academy