Clinical trials: Pathological Fracture
Stroke, Hip Fractures
Outcome of Rehabilitation of Older People in Primary Health Care
The Outcome of Multi-Disciplinary, Structured Rehabilitation of Older People in a District Inpatient Rehabilitation Centre is better than in a Standard Primary Health Care Rehabilitation Programme in Short Term Beds in Nursing…
- Conditions
- Stroke, Hip Fractures, Osteoarthritis, Chronic Disease
- Trial name
- NCT01457300
- Testing
- Rehabilitation
- Where
- 2 sites in Norway
- Volunteers
- 302 people
- Sponsor
- University of Oslo
Adynamic Bone Disease, Chronic Kidney Diseases
Treatment of Adynamic Bone Disorder With Parathyroid Hormone in Chronic Kidney Disease
This study is a 1:1 randomized controlled trial with an intervention for 18 months and a follow up period of 12 months. The purpose of the study is to assess the safety and efficacy of recombinant human parathyroid hormone for…
- Conditions
- Adynamic Bone Disease, Chronic Kidney Diseases, Cardiac Disease, Chronic Kidney Disease-Mineral and Bone Disorder
- Trial name
- NCT04522622
- Testing
- Teriparatide, DXA,VFA, X-ray, HR-pQCT, 18-F NAF PET/CT, Bone biopsy
- Where
- 4 sites in Denmark
- Volunteers
- 48 people
- Sponsor
- Ditte Hansen
Femoral Neck Fractures
Hemiarthroplasty or Internal Fixation for Displaced Femoral Neck Fractures
An estimated 1.6 million patients sustain a hip fracture every year, about half of these are intracapsular femoral neck fractures.
- Trial name
- NCT00464230
- Testing
- Bipolar hemiarthroplasty (Charnley/Hastings), Internal fixation with two parallel screws (Olmed)
- Where
- Norway
- Volunteers
- 220 people
- Sponsor
- Ullevaal University Hospital
Femoral Neck Fracture
The Effect of Periarticular Multi-Drug Regimen on Pain After Partial Hip Replacement
This prospective randomized study aims to evaluate the effectiveness of periarticular multi-drug regimen injection on the relief of pain in patients undergoing partial hip replacement.
- Trial name
- NCT01112436
- Testing
- periarticular injection of multidrug regimen, none of medication preoperatively and intraoperatively
- Where
- South Korea
- Volunteers
- 258 people
- Sponsor
- Chung-Ang University Hospital
Hip Fractures, Pain, Acute
The Impact of Integrated Preoperative Fascia Iliaca Compartment Block in Elderly Hip Fracture
This prospective randomized controlled study is aimed to determine the advantages of post-admission fascia iliaca compartment block (FICB) in geriatric hip fracture surgery combination with multimodal analgesia compared with no…
- Conditions
- Hip Fractures, Pain, Acute, Hip Fracture Surgery, Delirium in Old Age
- Trial name
- NCT05857462
- Testing
- Post-admission FICB
- Where
- Thailand
- Volunteers
- 420 people
- Sponsor
- Mahidol University
Pain, Acute
Evaluation of Pericapsular Nerve Group Block on Positioning Pain for Spinal Anesthesia in Hip Fracture Patients
The purpose of this study is to evaluate of analgesic effects of pericapsullar nerve group block which is performed preoperatively to assist positioning patients for performance of spinal anesthesia.
- Trial name
- NCT04871061
- Testing
- PENG Block, Conventional opioid analgesia (Fentanyl)
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Cigli Regional Training Hospital
Muscle Atrophy, Muscle Weakness
Evaluating Muscle Function After Ankle Surgery
Patients who are forced to rest or reduce activity as a result of illness, injury, or surgery often experience resulting muscle weakness.
- Conditions
- Muscle Atrophy, Muscle Weakness, Fractures
- Trial name
- NCT00060970
- Testing
- Physical Therapy
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Aging, Sarcopenia
A Prospective Cohort Study of Aged People for Chronic Diseases
This study is a hospital-based, prospective cohort study to elucidate the predictive factors including muscle and fat mass for chronic diseases and mortality in elderly persons aged 60 years and older.
- Trial name
- HAPPY (NCT02640872)
- Where
- South Korea
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Seoul National University Bundang Hospital
Depression, Old Age; Debility
Assessment of Depression Levels in Elderly Patients With an Orthopedic Fracture Compared to Patients After a Stroke.
Depression is common among elderly patients hospitalized due to acute conditions like strokes or osteoporotic fractures. It has significant impacts on quality of life, hospitalization rates, and mortality.
- Conditions
- Depression, Old Age; Debility, Stroke, Fractures, Bone
- Trial name
- NCT06570356
- Testing
- Geriatric Depression Scale - 15
- Where
- Israel
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Shmuel Harofeh Hospital, Geriatric Medical Center
Proximal Humeral Fracture, Dislocation
Proximal Humerus Fracture Dislocation Direction and Avascular Necrosis
The purpose of the study is to see if there is a connection between a proximal humerus fracture dislocation direction and the likelihood of developing avascular necrosis.
- Conditions
- Proximal Humeral Fracture, Dislocation, Dislocation Shoulder, Avascular Necrosis
- Trial name
- PHF-D (NCT05735561)
- Testing
- X-Ray
- Where
- Canada
- Volunteers
- 25 people
- Sponsor
- Fraser Orthopaedic Research Society
Hip Fractures
Regional Anesthesia by PENG-Block in Emergency Department
The study is a single-centre, open-label randomized comparative trial. Adult patients admitted to the emergency department for a hip fracture will be enrolled.
- Trial name
- ED-PENGBLOCK (NCT05673486)
- Testing
- PENG Block, Multimodal analgesia
- Where
- France
- Volunteers
- 36 people
- Sponsor
- Centre Hospitalier Intercommunal de Toulon La Seyne sur Mer
Osteoporosis, Fracture
Fragility Fracture Liaison Service and Anti-osteoporosis Medication Monitoring Service Study
Aims: (1) to Establish the FLS services at the National Taiwan University Hospital Jinshan Branch. (2) To establish a anti-osteoporosis medication management service at Jinshan Branch.
- Trial name
- NCT02635022
- Where
- Taiwan
- Volunteers
- 200 people
- Sponsor
- National Taiwan University Hospital
Heterotopic Ossification, Humeral Fractures
HO Prophylaxis Therapy for Distal Humerus Fractures
To determine the effectiveness of 500 cGy dose of radiation therapy vs. an untreated group in the prophylactic treatment of heterotopic ossification in distal humerus fractures
- Conditions
- Heterotopic Ossification, Humeral Fractures, Radiation Therapy
- Trial name
- NCT03724422
- Testing
- Radiation
- Where
- 2 sites in United States
- Volunteers
- 3 people
- Sponsor
- University of Louisville
Tibial Plateau Fracture, Pain, Postoperative
Saphenous Nerve Block After Tibial Plateau ORIF
Fractures of the tibial plateau, while very painful, typically do not receive nerve blocks. This is because of a concern that the numbness from a nerve block would "mask" the typically painful symptoms of compartment syndrome, a…
- Trial name
- NCT04314570
- Testing
- Saphenous Nerve Block with Ropivacaine Treatment, Saphenous Nerve Block with Saline Control
- Sponsor
- Stanford University
Frailty, Hip Fracture
Frailty, Hip Fractures and Inflammatory Biomarkers
We ought to investigate if hip fracture patients suffering from frailty have higher inflammatory burden according to simple inflammatory biomarkers.
- Conditions
- Frailty, Hip Fracture, Inflammatory Biomarkers
- Trial name
- NCT06614478
- Where
- 2 sites in Greece
- Volunteers
- 200 people
- Sponsor
- University of Thessaly
Non-inflammatory Degenerative Joint Disease, Osteoarthritis
Study to Evaluate the Safety and Effectiveness of REAL INTELLIGENCE™ CORI™ in Unicondylar Knee Arthroplasty (UKA) Procedures
This is a prospective study to demonstrate the safety and effectiveness of CORI and to register CORI in China mainland.
- Conditions
- Non-inflammatory Degenerative Joint Disease, Osteoarthritis, Avascular Necrosis, Requires Correction of Functional Deformity
- Trial name
- CORI RCT UKA (NCT04797897)
- Testing
- CORI, Conventional
- Where
- 3 sites in Australia, Hong Kong and 1 more
- Volunteers
- 4 people
- Sponsor
- Smith & Nephew, Inc.