Clinical trials: Pathological Fractures
Osteoporosis, Back Pain
VERTOS-II. Percutaneous Vertebroplasty Versus Conservative Therapy
Percutaneous vertebroplasty is a new procedure for treating painful osteoporotic compression fractures of the spine. Five-thousand out of 12.000 patients (16.000 vertebral fractures/year in the Netherlands) present with sudden…
- Trial name
- NCT00232466
- Testing
- Vertebroplasty
- Where
- 6 sites in Belgium, Netherlands
- Volunteers
- 200 people
- Sponsor
- Clinical Research Office Imaging Division
Femoral Fractures, Hemorrhage, Surgical
Effectiveness of Tranexamic Acid in Reducing Blood Loss During Femoral Nail Surgery
This clinical study aims to evaluate the safety and effectiveness of administering a single intravenous dose of tranexamic acid (TXA) before surgery to reduce blood loss in patients undergoing open intramedullary nailing for…
- Conditions
- Femoral Fractures, Hemorrhage, Surgical, Tranexamic Acid Use
- Trial name
- TXA-FemNail (NCT07261930)
- Testing
- Tranexamic Acid
- Where
- Uganda
- Volunteers
- 43 people
- Sponsor
- Masaka Regional Referral Hospital
Hip Fracture, Postoperative Pain
Effect of PENG Block on Postoperative Tramadol Consumption in Partial Hip Prosthesis Surgery
This study aims to evaluate the effect of ultrasound-guided pericapsular nerve group (PENG) block on postoperative tramadol consumption, pain scores, and clinical outcomes in patients undergoing partial hip prosthesis surgery.
- Trial name
- PENG-PKP (NCT07534137)
- Testing
- PENG Block, General Anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people
- Sponsor
- University of Gaziantep
Emergency Department Procedural Sedation, Fracture Reduction
Ketofol Versus Fentofol for Procedural Sedation in the Pediatric Emergency Department
Sedation and pain medication is required when bone fractures need to be fixed in the emergency department (ED). Many drugs have been used safely as single agents or in combination for the sedation of children.
- Trial name
- NCT02079090
- Testing
- Ketofol, Fentofol
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- University of British Columbia
Acute Pain
Efficacy of Buprenorphine for Treatment of Acute Pain
The purpose of this study is to determine whether sublingual buprenorphine is effective in the treatment of acute pain in adult patients with extremity bone fractures
- Trial name
- NCT01298297
- Testing
- Buprenorphine, Morphine
- Where
- Iran
- Volunteers
- 80 people
- Sponsor
- Tehran University of Medical Sciences
Forearm Injuries, Pain, Acute
Pain Control Differences Between Oxycodone and Ibuprofen in Children With Isolated Forearm Injuries
Children presenting to the Emergency Room with the chief complaint of forearm injury and/or pain will be randomized to receive oral Oxycodone or Ibuprofen to control pain.
- Conditions
- Forearm Injuries, Pain, Acute, Pediatric ALL
- Trial name
- NCT04523623
- Testing
- Oxycodone, Ibuprofen
- Sponsor
- Washington University School of Medicine
Clavicle Fracture
Percutaneous Versus Open Plate Fixation of Diaphyseal Clavicle Fractures
This is a prospective, level II evidence comparison between two cohorts. This study is designed to compare the percutaneous versus open approach for plate fixation of diaphyseal clavicle fractures.
- Trial name
- NCT01405703
- Testing
- xrays
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- University of Utah
Hip Fractures, Anesthesia
Does Optimized General Anesthesia Care Reduce Postoperative Delirium?
Postoperative delirium occurs in up to 65% of elders undergoing surgery for repair of a hip fracture and this complication is independently associated with increased morbidity, mortality, length of hospital stay, and placement in…
- Conditions
- Hip Fractures, Anesthesia, Delirium
- Trial name
- OPCare (NCT02604459)
- Testing
- cerebral oximeter (Fore-Sight), depth of anesthesia monitor (BIS), BP management
- Where
- United States
- Volunteers
- 145 people
- Sponsor
- University of Missouri-Columbia
Fracture, Pain
Racial and Ethnic Disparities in Acute Pain Control
We aim to compare pain management among three groups of ethnic disparity (ED) patients, Hispanics, non-Hispanic Blacks, non-Hispanic Whites, and assess whether the observed association between pain management and race/ethnicity…
- Trial name
- NCT00115180
- Testing
- No intervention
- Where
- 2 sites in United States
- Volunteers
- 285 people
- Sponsor
- Agency for Healthcare Research and Quality (AHRQ)
Hip Fractures, Pain, Acute
The Impact of Integrated Preoperative Fascia Iliaca Compartment Block in Elderly Hip Fracture
This prospective randomized controlled study is aimed to determine the advantages of post-admission fascia iliaca compartment block (FICB) in geriatric hip fracture surgery combination with multimodal analgesia compared with no…
- Conditions
- Hip Fractures, Pain, Acute, Hip Fracture Surgery, Delirium in Old Age
- Trial name
- NCT05857462
- Testing
- Post-admission FICB
- Where
- Thailand
- Volunteers
- 420 people
- Sponsor
- Mahidol University
Cystic Echinococcus
Periprosthetic Fracture Following Tibial Echinococcosis
Cystic Echinococcus in the bone is rare, comprising 0.5% to 2.5% of all human hydatidosis Association of Hydatid disease to pathologic fractures involving knee prosthesis have not yet been described A combined surgical and…
- Trial name
- NCT03622346
- Testing
- Semi-constrained total knee arthroplasty
- Volunteers
- 1 people
- Sponsor
- Centro Hospitalar do Medio Tejo
Fractures, Sprain
Epidemiology of Incidents and Accidents in Sport. Influence of Moisture.
sports accidents and incidents are relatively frequent. We hypothesize that the pursuit of good hydration, including days without training or competition could prevent their occurrence
- Conditions
- Fractures, Sprain, Stress Fractures, Aches
- Trial name
- NCT02346786
- Testing
- eau minérale d'Aix-Les-Bains, tap water
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Centre de Recherche Rhumatologique et Thermal
Sepsis, Hip Fractures
The Association Between Preoperative Sepsis and the Mortality After Hip Fracture Surgery
The worldwide occurrence of hip fracture is high with an annual incidence of approximately 100 per 100.000 people. Mortality for patients undergoing hip fracture surgery is high with a 30-day mortality rate varying between 4.5…
- Trial name
- NCT03201679
- Testing
- Repair of hip fracture
- Volunteers
- 1,967 people
- Sponsor
- Bispebjerg Hospital
Hip Fractures, Pain, Acute
Pericapsular Nerve Group Block for Hip Fractures
This will be a feasibility study to see if it feasible to perform the Pericapsular Nerve Group Block for hip fractures in the Emergency Department.
- Trial name
- NCT04882384
- Testing
- Pericapsular Nerve Group Block
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Jacobi Medical Center
Primary Osteoarthritis, Secondary Osteoarthritis
Clinical and Radiological Outcomes of Medacta Shoulder System (BE)
This is a post-market surveillance study on Medacta Shoulder System
- Conditions
- Primary Osteoarthritis, Secondary Osteoarthritis, Rotator Cuff Tear Arthropathy, Rheumatoid Arthritis Shoulder
- Trial name
- NCT05002335
- Testing
- Medacta Shoulder System
- Where
- 3 sites in Belgium
- Volunteers
- 200 people
- Sponsor
- Medacta International SA
Sarcopenia
Combined Exercise and Nutrition Intervention for Sarcopenia
This study aims to demonstrate the effect of combined exercise-nutrition intervention in old adults with sarcopenia. This study will be conducted with prospectively randomized controlled trial comparing outcome of combined…
- Trial name
- NCT06654648
- Testing
- Combined exercise nutrition intervention group, Conventional medial care group
- Where
- South Korea
- Volunteers
- 118 people
- Sponsor
- Seoul Bumin Hospital
Hip Fractures, Stroke
Feasibility of the Geriatric Activation Program Pellenberg With Caregiver Involvement
This interventional study aims to see if involving caregivers as exercise partners with the physiotherapist throughout in-hospital geriatric rehabilitation and the first six weeks following discharge is feasible.
- Conditions
- Hip Fractures, Stroke, Frailty
- Trial name
- NCT05419284
- Testing
- GAPP+Care, +Care, Observation of GAPP+Care
- Where
- Belgium
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- KU Leuven
Bradycardia
Falls and Cardiovascular Events in Pacemaker Patients
The purpose of this study is to document the number of falls and fractures in Sinus Node Disease (SND) patients.
- Trial name
- NCT01037426
- Testing
- Fill out Questionnaire
- Where
- 8 sites in Switzerland
- Volunteers
- 87 people
- Sponsor
- Medtronic Cardiac Rhythm and Heart Failure
Fractures Reduction, Joint Dislocation Reduction
Incidence of Recall After Procedural Sedation With Propofol in the Emergency Department
The purpose of this study is to determine the incidence of recall in patients managed in emergency department with a procedural sedation protocol using propofol in a population of 250 .
- Trial name
- MEMOPROPO (NCT02200744)
- Where
- 4 sites in France
- Volunteers
- 248 people
- Sponsor
- Centre Hospitalier Universitaire de la Réunion
Osteoporotic Fractures, Vertebral Fracture
Percutaneous Vertebroplasty Vs. Sham for Osteoporotic Vertebral Compression Fractures Focusing on Pain and Economy.
The purpose of this randomized double-blind clinical trial is to determine the efficacy of percutaneous vertebroplasty (PVP) in relieving severe pain in patients with MRI-verified acute or sub-acute osteoporotic vertebral…
- Trial name
- VOPE2 (NCT06141187)
- Testing
- Vertebroplasty
- Where
- Denmark
- Volunteers
- 240 people
- Sponsor
- Spine Centre of Southern Denmark