Clinical trials: Pathological Fractures
Radial Fracture
Radius Fracture Anesthesia and Rehabilitation (RADAR)
Distal fracture of the radial bone is the commonest fracture and is also connected to osteoporosis. Normally the operation is performed under neuroaxial blockade and sedation.
- Trial name
- RADAR (NCT03749174)
- Testing
- Long acting Supraclivicular block vs Short acting Supraclavicular block
- Where
- Sweden
- Volunteers
- 120 people
- Sponsor
- Sahlgrenska University Hospital
Elbow Fracture
Percutaneous Pin Removal in Children - is Analgesia Necessary?
This is a simple randomised clinical trial to study if non-narcotic analgesia reduces the pain score and pulse rate of children who undergo removal of percutaneous pins in the outpatient clinic.
- Trial name
- NCT01944085
- Testing
- Acetaminophen, Ibuprofen, Vitamin C
- Where
- Singapore
- Volunteers
- 240 people
- Sponsor
- KK Women's and Children's Hospital
Obesity, Weight Loss
Utilizing Protein During Weight Loss to Impact Physical Function and Bone
This study is an ancillary study to the Utilizing Protein During Weight Loss to Impact Physical Function (UPLIFT) trial (NCT03074643) to evaluate the effects of diet composition (i.e., amount of protein and carbohydrate) during a…
- Conditions
- Obesity, Weight Loss, Diet Modification, Aging
- Trial name
- UPLIFT-Bone (NCT03819478)
- Testing
- Weight loss intervention months 0-6, Exercise intervention months 0-6, NutraBio™ CarboMax Supplement
- Where
- United States
- Volunteers
- 187 people
- Sponsor
- Wake Forest University Health Sciences
Intertrochanteric Fractures
The Effect of Loss of Offset After Pertrochanteric Fracture Treated With a Intramedullary Nail
The purpose of this study is determine the relationship between pain and protrusion of the implant after surgery for a intertrochanteric fracture.
- Trial name
- PLAIN (NCT01344785)
- Testing
- Intramedullary nailing
- Where
- Sweden
- Volunteers
- 100 people
- Sponsor
- Danderyd Hospital
Pain, Postoperative, Fractures, Closed
Cognitive Behavioural Therapy to Reduce Persistent Post-Surgical Pain After Fracture
Psychological factors such as stress, distress, anxiety, depression, and poor coping strategies may be associated with ongoing pain following injuries such as fractures.
- Conditions
- Pain, Postoperative, Fractures, Closed, Fractures, Open
- Trial name
- SPOC_CBT (NCT03196258)
- Testing
- Cognitive behavioural therapy
- Where
- Canada
- Volunteers
- 8 people
- Sponsor
- McMaster University
Postoperative Pain
Evaluation of PENG Block in Terms of Block Time and Postoperative Pain
Hip fracture is a common orthopedic emergency in the elderly and causes significant morbidity and is associated with mortality. In most patients, surgical reduction and fixation is the definitive treatment.
- Trial name
- NCT06132308
- Testing
- PENG Block with 0.25% bupivacaine
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Diskapi Yildirim Beyazit Education and Research Hospital
Chronic Obstructive Pulmonary Disease, Proximal Femur Fracture
European Quality of Care Pathways Study on the Effect of Care Pathways on Interprofessional Teamwork (EQCP-TEAM)
Care pathways are complex interventions to support the interprofessional team in the redesign of their care process. This international cluster randomised trial will analyse the impact of the development and implementation of…
- Trial name
- EQCP-TEAM (NCT01435538)
- Testing
- Care pathway.
- Where
- Belgium
- Volunteers
- 984 people
- Sponsor
- Dr. Kris Vanhaecht
Atrial Fibrillation
Medical Need of OAC Reversal
This is a retrospective, observational, claims cohort study to assess, for adult patients initiating an oral anticoagulant for NVAF
- Trial name
- NCT03254147
- Testing
- warfarin, dabigatran, Apixaban
- Where
- Japan
- Volunteers
- 53,969 people
- Sponsor
- Boehringer Ingelheim
Osteoporosis
Prevalence of Osteoporosis and Fractures in Patients With Hepatic Cirrhosis and Investigation of the Associated Factors
Osteoporosis is a common complication in chronic liver disease, especially in the late stages of the disease. Good nutrition and calcium and vitamin D supplementation are recommended for the prevention and treatment of…
- Trial name
- POC (NCT03201016)
- Testing
- Bone densitometry
- Where
- Spain
- Volunteers
- 110 people
- Sponsor
- Corporacion Parc Tauli
Elective Hip Fracture Surgery
Whey Intake Blood Glucose, Fasting, Thirst, Nausea and Vomiting Levels of Patients Undergoing Elective Hip Fracture Surgery
Whey Intake Blood Glucose, Fasting, Thirst, Nausea, Vomiting Elective Hip Fracture Surgery
- Trial name
- NCT06316648
- Testing
- whey intake group, control group
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- TC Erciyes University
Fractures, Comminuted, Surgical Wound Dehiscence
Application of Indocyanine Green Angiography for Closed Operative Calcaneus Fractures
Researchers in the Orthopaedic surgery department at LSU Medical Center-Shreveport hope to learn if patterns of blood-flow around the incision site of patients undergoing surgery for heel-bone fractures can help predict whether…
- Conditions
- Fractures, Comminuted, Surgical Wound Dehiscence, Necrosis
- Trial name
- NCT01693484
- Testing
- ICG (Indocyanine Green)
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Louisiana State University Health Sciences Center Shreveport
Rheumatoid Arthritis, Osteoarthritis
Multi-centre Study to Assess the Long-term Performance of the Deltamotion Cup System in Primary Hip Replacement Surgery
The purpose of this study is to monitor the performance of the DeltaMotion cup system in the treatment of patients with hip joint disease requiring a total hip replacement.Patients who enter the study will be evaluated at regular…
- Conditions
- Rheumatoid Arthritis, Osteoarthritis, Post-traumatic Arthritis, Avascular Necrosis
- Trial name
- NCT01635166
- Testing
- Delta Motion
- Where
- 3 sites in India, United Kingdom
- Volunteers
- 250 people
- Sponsor
- DePuy International
Osteoarthritis, Post-traumatic Arthritis
A Randomised Single Centre Study to Compare the Long-term Performance of 4 Designs of the DePuy Ultima LX Stem in Primary Total Hip Replacement
The purpose of this study is to compare the performance of 4 designs of the DePuy Ultima LX hip stem in the treatment of patients with hip joint disease requiring a total hip replacement.
- Conditions
- Osteoarthritis, Post-traumatic Arthritis, Collagen Disorder, Avascular Necrosis
- Trial name
- NCT00208351
- Testing
- Ultima LX Collared Stem - Non-Polished/Blasted Finished, Ultima LX Collared Stem - Polished Finished, Ultima LX Collarless Stem - Non-Polished/Blasted Finished
- Where
- United Kingdom
- Volunteers
- 164 people
- Sponsor
- DePuy International
Intensive Care Unit Patients, Pain Management
Effects of Voice Records on Patient Outcomes Surgical Intensive Care Unit
This randomized kontrolled study is aimed to contribute to the literature on recognising, evaluating and reducing stress in the intensive care unit, which is one of the main responsibilities of surgical nurses, and to increase…
- Conditions
- Intensive Care Unit Patients, Pain Management, Stress Response
- Trial name
- NCT07007754
- Testing
- Voice recording playback
- Where
- Turkey (Türkiye)
- Volunteers
- 69 people
- Sponsor
- Aydin Adnan Menderes University
Sarcopenia in Elderly, Sarcopenic Obesity
Comparative Analysis of Sarcopenia in Rehabilitation Outcomes Following Femoral Neck Fracture: a Study in Normal Weight and Obese Study Cohort
Impact of Obesity on Sarcopenia Prevalence and Severity in Elderly Adults Recovering from Femoral Neck Fractures: A Prospective Study Introduction Age-related muscle loss, or sarcopenia, which includes reductions in both muscle…
- Conditions
- Sarcopenia in Elderly, Sarcopenic Obesity, Frailty, Femoral Fractures
- Trial name
- NCT06705166
- Volunteers
- 300 people
- Sponsor
- Shmuel Harofeh Hospital, Geriatric Medical Center
Distal Radius Fracture
The Effect of Kinesio Taping on Edema Control and Wrist Functions in Conservatively Followed Distal Radius Fractures.
Kinesio tape is used successfully in the control of edema related to the extremity, especially in the control of lymphedema that develops after surgery.Kinesiotape is a non-allergic elastic tape applied to the skin surface.There…
- Trial name
- NCT05623865
- Testing
- kinesiotaping, exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 61 people
- Sponsor
- Ahi Evran University Education and Research Hospital
Chronic Renal Failure, Kidney Transplant Patients
Study of Trabecular Bone Score (TBS) as a Fracture Risk Factor in Chronic Renal Failure
Observational study
- Trial name
- TRIFIR (NCT03356522)
- Where
- France
- Volunteers
- 206 people
- Sponsor
- Rennes University Hospital
Pain, Acute, Postoperative Pain
Use of Dexamethasone Via Two Different Methods in PENG Block
Hip fractures are morbid conditions, especially in elderly patients, and their treatment is usually surgical. Pericapsular nerve group block targets the hip capsule.
- Conditions
- Pain, Acute, Postoperative Pain, Hip Fractures
- Trial name
- NCT06242028
- Testing
- Group P, Group S
- Where
- Turkey (Türkiye)
- Volunteers
- 44 people
- Sponsor
- Ondokuz Mayıs University
Atrial Septal Defect (ASD), Dexmedetomidine
Effect of Dexmedetomidine Supplementation to General Anaesthesia in Paediatric Transcatheter Closure of Atrial Septal Defect
The aim of this randomized trial is to determine efficacy of dexmedetomidine in improving quality of recovery in pediatric patients undergoing interventional catheter closure of ASD while maintaining the hemodynamic parameters.
- Conditions
- Atrial Septal Defect (ASD), Dexmedetomidine, Delirium - Postoperative, Stress Response
- Trial name
- NCT06631534
- Testing
- Dexmedetomidine
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Alexandria University
Elbow Fracture
Comparison of Mobilization and MET Post-Traumatic Elbow Stiffness
The purpose of this study is to find the effects of Mobilization and Muscle energy technique in patients with post-traumatic elbow stiffness.
- Trial name
- MET (NCT05258162)
- Testing
- Mobilization, Muscle Energy Technique
- Where
- Pakistan
- Volunteers
- 30 people
- Sponsor
- Riphah International University