Clinical trials: Pathological Fractures
Vitamin D Deficiency, Obesity
D-tecting Disease - From Exposure to Vitamin D During Critical Periods of Life
Vitamin D deficiency is common among otherwise healthy pregnant women and may have consequences for them as well as the early development and long-term health of their children.
- Conditions
- Vitamin D Deficiency, Obesity, Diabetes Mellitus, Pre-Eclampsia
- Trial name
- D-tect (NCT03330301)
- Testing
- D-tect
- Where
- Denmark
- Volunteers
- 222,776 people
- Sponsor
- Bispebjerg Hospital
Geriatric Patients
The Effect of Training Prepared in Line With Fracture Liaison Service Model on Frailty in Hip Surgery Patients
This study is a randomized controlled experimental research with pretest-posttest control group. The aim of this study is to evaluate the effect of the training prepared in line with the fracture liaison service model on the…
- Trial name
- NCT05900804
- Testing
- Training Prepared in Line with the Fracture Liaison Service Model
- Where
- Turkey (Türkiye)
- Volunteers
- 74 people
- Sponsor
- Aydin Adnan Menderes University
Hip Fractures, Pain, Postoperative
The Effect of TENS on Pain and Analgesic Consumption
The surgical treatment of an individual with osteoarthritis and hip fracture is provided by hip replacement surgery. While restructuring the joint surfaces with surgery, it is aimed to provide both hip joint movements and to…
- Conditions
- Hip Fractures, Pain, Postoperative, Analgesia
- Trial name
- NCT05939804
- Testing
- TENS
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Cukurova University
Coronary Heart Disease, Stroke
Examining the Long-Term Risks of Oophorectomy
At the time of hysterectomy for benign disease, the overall health benefits of preserving ovarian function in a large population of women have not been established.
- Conditions
- Coronary Heart Disease, Stroke, Breast Cancer, Ovarian Cancer
- Trial name
- NCT00655447
- Where
- United States
- Volunteers
- 32,175 people, healthy volunteers welcome
- Sponsor
- Parker, William H., M.D.
Wound Infection, Fractures, Open
Tobramycin Injection to Prevent Infection in Open Fractures
The goal of open extremity fracture (OEF) treatment is to promote fracture healing and restore function while preventing the development of infection.
- Conditions
- Wound Infection, Fractures, Open, Surgical Site Infection
- Trial name
- NCT04964947
- Testing
- Tobramycin Injection
- Where
- 3 sites in United States
- Volunteers
- 600 people
- Sponsor
- Massachusetts General Hospital
Stroke, Hip Fractures
Outcome of Rehabilitation of Older People in Primary Health Care
The Outcome of Multi-Disciplinary, Structured Rehabilitation of Older People in a District Inpatient Rehabilitation Centre is better than in a Standard Primary Health Care Rehabilitation Programme in Short Term Beds in Nursing…
- Conditions
- Stroke, Hip Fractures, Osteoarthritis, Chronic Disease
- Trial name
- NCT01457300
- Testing
- Rehabilitation
- Where
- 2 sites in Norway
- Volunteers
- 302 people
- Sponsor
- University of Oslo
Humeral Fractures, Fractures, Closed
Pain Management in Children Undergoing Supracondylar Humerus Fracture Repair
The purpose of this study is to determine if US-guided supraclavicular anesthetic blocks reduce postoperative pain, use of rescue medication, and improve functional outcomes in children who underwent surgery for supracondylar…
- Trial name
- NCT01812863
- Testing
- Supraclavicular nerve block
- Where
- United States
- Sponsor
- Ann & Robert H Lurie Children's Hospital of Chicago
Osteoporosis, Frailty
Spitex-SpiTal-Autonomie-Reha-Kraft
The primary purpose of this study is to test if the STARK comprehensive autonomy health care package improves lower extremity function over time at 6 weeks, 3, 6 and 12 months after hip or pelvis fracture compared to the standard…
- Conditions
- Osteoporosis, Frailty, Hip Fractures
- Trial name
- STARK (NCT03154684)
- Testing
- STARK intervention, Standard of Care
- Where
- Switzerland
- Volunteers
- 5 people
- Sponsor
- University of Zurich
Rib Fractures, Pain, Acute
Blue Light as an Anti-inflammatory and Analgesic Strategy in Thoracic Trauma
The main goal of this clinical trial is to learn if light therapy improves pain and inflammation in adults with painful rib fractures.
- Trial name
- BLAASTT (NCT06626334)
- Testing
- Bright Blue Light, Bright Full-Spectrum (White) Light, Usual Ambient Light
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- Rebecca E Kotcher, MD
Osteoarthritis, Rheumatoid Arthritis
Outcomes Study of the TM Humeral Stem Used in Primary, Total or Hemi Shoulder Arthroplasty
The objectives of this study are to obtain survival and outcome data on the Trabecular Metal Humeral Stem when used in primary, total or hemi shoulder arthroplasty.
- Conditions
- Osteoarthritis, Rheumatoid Arthritis, Post-traumatic Arthritis, Ununited Humeral Head Fracture
- Trial name
- NCT01480453
- Testing
- Trabecular Metal Humeral Stem
- Where
- 3 sites in United States
- Volunteers
- 67 people
- Sponsor
- Zimmer Biomet
Femoral Neck Fractures, Hemiarthroplasty
Efficacy of Intraoperative Periarticular Injections in Hip Fracture Hemiarthroplasty
The objective of this study was to assess the effectiveness of the intraoperative periarticular solution in reducing blood loss and minimizing transfusion requirements in patients with femoral neck fractures who underwent…
- Conditions
- Femoral Neck Fractures, Hemiarthroplasty, Blood Loss Requiring Transfusion
- Trial name
- NCT06701695
- Testing
- Periarticular Injection (PAI), Control (Standard treatment)
- Where
- Turkey (Türkiye)
- Volunteers
- 84 people
- Sponsor
- Ankara City Hospital Bilkent
Alcohol Use Disorder, Stress Reaction
Neurobehavioral Profiles of Adaptive Stress Responses in Individuals With Alcohol Use Disorder
The goal of this observational study is to investigate longitudinal stress response profiles and adaptive versus non-adaptive stress responses in alcohol use disorder.
- Conditions
- Alcohol Use Disorder, Stress Reaction, Social Stress, Craving
- Trial name
- A03 (NCT06105853)
- Testing
- Trier Social Stress Test, Barlab Cue-Exposure, Functional magnetic resonance imaging
- Where
- 2 sites in Germany
- Volunteers
- 100 people
- Sponsor
- Central Institute of Mental Health, Mannheim
Rib Fractures, Oxygenation
Deep Breathing Exercises and Incentive Spirometry After Rib Fracture
Chest trauma patients constitute approximately 10-15% of all traffic accidents. Many complications may occur after chest trauma, including rib fracture, pneumothorax, hemothorax, lung contusion, flail chest, atelectasis…
- Trial name
- NCT06853002
- Testing
- Breathing exercise with spirometry, Breathing exercise with deep breathing method
- Where
- Turkey (Türkiye)
- Volunteers
- 104 people
- Sponsor
- Samsun University
Wrist Fracture
Axillary Block in Association With Analgesic Truncal Blocks at the Elbow for Wrist Surgery.
Fractures of the forearm bones that occur around the wrist are common in the elderly. Standard anesthesia for its surgical treatment is regional anesthesia (RA): supraclavicular block, infraclavicular block or axillary block…
- Trial name
- BAXASSO (NCT04046744)
- Testing
- Axillary brachial plexus block with a long-acting local anesthetic, Axillary brachial plexus block with a short-acting local anesthetic + Analgesic block at the elbow with a long-acting local anesthetic, Ropivacaine
- Where
- 7 sites in France
- Volunteers
- 150 people
- Sponsor
- CMC Ambroise Paré
Ankle Fractures, Intra-Articular Fractures
Prevention of Posttraumatic Osteoarthritis After Acute Intraarticular Fractures
Intra-articular fracture is a very common fracture. The only method to treat these fractures is surgery with plate and screws followed by rehabilitation.
- Conditions
- Ankle Fractures, Intra-Articular Fractures, Osteoarthritis
- Trial name
- NCT03769909
- Where
- Denmark
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- University of Southern Denmark
Opioid Use, Post-operative Pain
Standardization of Post-operative Opiate Prescriptions for Same-day Ankle and Wrist Fracture Surgeries
The purpose of this prospective cohort study is to evaluate the opiate prescribing patterns post open reduction and internal fixation (ORIF) of wrist and ankle fractures at the Ottawa Hospital.
- Conditions
- Opioid Use, Post-operative Pain, Prescription Opioid Abuse, Fracture, Ankle
- Trial name
- NCT05322564
- Testing
- Standardized opiate prescription
- Volunteers
- 100 people
- Sponsor
- The Ottawa Hospital
Fracture, Frailty
The CHARM Study-Coordinating Transitions from Hospital for Older Adults with Fractures
Background: Fall-related injuries like fractures are on the rise among older adults in New Brunswick. These injuries can lead to hospitalization and adverse health effects.
- Conditions
- Fracture, Frailty, Aging
- Trial name
- NCT06107699
- Testing
- Patient Navigation
- Where
- Canada
- Volunteers
- 70 people
- Sponsor
- Horizon Health Network
Postoperative Pain, Wrist Fracture
Comparing Efficacity of Analgesia Between Ultrasound-guided Nerve Block and Local Infiltration After Wrist Fracture Surgery
Distal radial fracture reparations by volar plating are often managed under regional anaesthesia, but are associated with severe pain when the block ends.
- Trial name
- BNINF (NCT02693288)
- Testing
- Local infiltration anesthesia
- Where
- France
- Volunteers
- 72 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Health, Subjective, Nutrition Disorders
Relative Energy Deficiency in Sport Multicenter Study
Relative Energy Deficiency in Sport (RED-S) characterizes a range of negative health and performance outcomes that result from chronically low energy availability.
- Conditions
- Health, Subjective, Nutrition Disorders, Athletic Injuries, Hormone Disturbance
- Trial name
- NCT04766203
- Testing
- Treatment of REDS using a holistic treatment arm
- Where
- Canada
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Trent Stellingwerff
Calcaneus Fracture, Displaced Intra-Articular Fracture of Calcaneus (Diagnosis)
Permissive Weight Bearing in Displaced Intra-articular Calcaneal Fractures
The goal of the proposed study is to define the optimal rehabilitation for trauma patients with Displaced Intra-articular Calcaneal Fractures, either Permissive Weight Bearing (PWB) or Restricted Weight Bearing (RWB) regarding…
- Conditions
- Calcaneus Fracture, Displaced Intra-Articular Fracture of Calcaneus (Diagnosis), Trauma Injury
- Trial name
- PIONEER (NCT05721378)
- Testing
- Permissive Weight Bearing group, Restricted Weight Bearing group
- Where
- 11 sites in Netherlands
- Volunteers
- 115 people
- Sponsor
- Maastricht University Medical Center