Clinical trials: Pathological Fractures
Magnetic Resonance Imaging, Hip Fractures
fMRI Feasibility Older Hip Fracture Surgery
An assessment of the feasibility of structural and functional magnetic resonance imaging (MRI) brain scans in older people who have recovered from and older people who never had delirium after hip fracture surgery
- Conditions
- Magnetic Resonance Imaging, Hip Fractures, Postoperative Delirium
- Trial name
- NCT05081726
- Testing
- Functional MRI
- Volunteers
- 10 people
- Sponsor
- University of Nottingham
Rib Fractures, Rib Fracture Multiple
US-guided SAPB for Rib Fractures in the ED
The purpose of this randomized controlled study is to determine whether the serratus anterior plane block reduces pain more than the usual treatment for rib fractures in the same amount of time.
- Trial name
- NCT03619785
- Testing
- Bupivacaine, Fentanyl, morphine, hydromorphone, hydrocodone, acetaminophen, ketorolac, gabapentin, ketamine, ibuprofen
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Andrew A Herring
Hip Fractures
Effects of a Supplement Enriched in Hydroxymethylbutyrate and Vitamin D on Muscle Strength in Hip Fracture
The purpose of this study is to determine whether a nutritional supplement high in protein and energy, and enriched with hydroxymethylbutyrate (HMB) and vitamin D is more effective than a standard nutritional supplement high in…
- Trial name
- NCT01850251
- Testing
- Supplement with HMB and vitamin D, Standard nutritional supplement
- Where
- Spain
- Volunteers
- 2 people
- Sponsor
- Hospital Clinic of Barcelona
Coxarthrosis; Primary, Coxarthrosis; Post-Traumatic
Cemented TrendHip® - Multicenter PMCF Study on Total Indications
This Post Market Clinical Follow-Up (PMCF) study to evaluate the performance and safety of the cemented TrendHip® stem in a prospective follow-up study with patients who underwent a hip arthroplasty with the investigational…
- Conditions
- Coxarthrosis; Primary, Coxarthrosis; Post-Traumatic, Necrosis, Femur Head, Rheumatoid Arthritis
- Trial name
- TRESTI (NCT04943328)
- Testing
- Total Hip Arthroplasty
- Where
- 4 sites in Germany
- Volunteers
- 119 people
- Sponsor
- Aesculap AG
Pain, Bone Fracture
Dexketoprofen and Ibuprofen in Long Bone Fractures
The aim of this study was to compare the efficacy of ibuprofen and dexketoprofen, two common analgesic drugs used in pain control in patients with long bone fractures.
- Trial name
- NCT06060236
- Testing
- Ibuprofen 800 mg, Dexketoprofen
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Ankara City Hospital Bilkent
Delirium
Evaluation of the Effectiveness of Delirium Preventive Care Protocol
The prospective, randomized controlled experimental trial investigates the effectiveness of delirium preventive care protocol for hip fracture patients.
- Trial name
- NCT04188795
- Testing
- Delirium Preventive Care Protocol
- Where
- 3 sites in Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Saglik Bilimleri Universitesi Gulhane Tip Fakultesi
Wrist Injuries, Wrist Fracture
Splinted Wrist Study
Randomized clinical trial comparing SAM aluminium splint vs pain relief as usual in patients seeking emergency department care for suspected wrist fractures.
- Conditions
- Wrist Injuries, Wrist Fracture, Pain, Acute
- Trial name
- NCT07553000
- Testing
- SAM splint
- Where
- Sweden
- Volunteers
- 120 people
- Sponsor
- Region Skane
Shoulder Pain, Shoulder Injuries
MDR - Comprehensive Primary Revision Stems PMCF
The objective of this retrospective and prospective consecutive series PMCF (Post Market Clinical Follow Up) study is to collect long-term data confirming safety, performance and clinical benefits of the Comprehensive Primary…
- Conditions
- Shoulder Pain, Shoulder Injuries, Shoulder Fractures, Shoulder Disease
- Trial name
- NCT06788717
- Testing
- Comprehensive Primary Revision Stems
- Where
- 2 sites in United States, Denmark
- Volunteers
- 59 people
- Sponsor
- Zimmer Biomet
Osteoarthritis, Arthritis
Periprosthetic Bone Mineral Density After Total Hip Arthroplasty Performed Through a Minimally Invasive Anterior Approach (AMIS) With Either an AMIStem or a Quadra Femoral Component
This is a monocentric, prospective, randomized clinical survey to verify if the periprosthetic remodelling brought about either the AMIStem or the Quadra femoral component is equivalent.
- Conditions
- Osteoarthritis, Arthritis, Avascular Necrosis, Fracture of the Femoral Neck or Head
- Trial name
- NCT01285843
- Testing
- Anterior Minimally Invasive Approach (AMIS)
- Where
- Germany
- Volunteers
- 40 people
- Sponsor
- Medacta International SA
Lactate Blood Increase, Trauma Blunt
Lactate Monitoring in Traumatic Long Bone Fractures Requiring Emergent Surgical Intervention
Serum lactate has been utilized as a standard in guiding management of orthopedic injuries. Elevated preoperative lactate has been associated with a higher likelihood of postoperative complications.
- Conditions
- Lactate Blood Increase, Trauma Blunt, Trauma, Secondary, Injury Traumatic
- Trial name
- NCT05611398
- Testing
- Orthopedic Surgery
- Where
- United States
- Volunteers
- 164 people
- Sponsor
- Arrowhead Regional Medical Center
Fracture, Influenza Vaccination
Influenza Vaccination Against Infectious Complications and Mortality in Older Adults With Fractures: a Large-scale Retrospective Cohort Study
Background: Both influenza and bone fractures are significant contributors to morbidity and mortality among older adults. This study evaluated the associations between influenza vaccination (IV) and adverse outcomes following…
- Trial name
- NCT07231016
- Where
- Taiwan
- Volunteers
- 561,566 people, healthy volunteers welcome
- Sponsor
- Taipei Medical University Hospital
Pain, Hip Fracture
Intravenous Acetaminophen as Adjuvant Therapy for Pain Control in Geriatric Hip Fracture Patients
This research study is a prospective, randomized, blinded, placebo controlled trial evaluating the benefit of IV acetaminophen (Ofirmev™) as adjuvant analgesia in geriatric hip fracture patients.
- Trial name
- NCT01520298
- Testing
- Acetaminophen IV
- Where
- United States
- Sponsor
- Lancaster General Hospital
Trauma, Inflammation
Effect of C1-esterase Inhibitor on Systemic Inflammation in Trauma Patients With a Femur or Pelvic Fracture
Trauma and major operation are associated with an excessive inflammation reaction due to tissue injury. This overwhelming immune response is considered to be a major risk factor in the pathogenesis of late inflammatory…
- Conditions
- Trauma, Inflammation, Sepsis, Multiple Organ Dysfunction Syndrome
- Trial name
- CAESAR (NCT01275976)
- Testing
- C1-esterase inhibitor, Saline 0.9%
- Where
- Netherlands
- Volunteers
- 11 people
- Sponsor
- UMC Utrecht
Menopause, Gait, Unsteady
Effects of Strength Training on the Gait and Pelvic Floor in Menopausal Women
The overall objective will be to observe whether a strength and balance training intervention produces significant changes in the analysis of double stance phase movement during gait, the analysis of coxofemoral, tibial and…
- Conditions
- Menopause, Gait, Unsteady, Pelvic Floor Disorders
- Trial name
- NCT07824947
- Testing
- Strength training
- Where
- Spain
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- University of Alcala
Osteoarthritis, Rheumatoid Arthritis
Outcomes Study of the Trabecular Metal (TM) Reverse Shoulder System
The objectives of this study are to obtain survival and outcome data on the Trabecular Metal Reverse Shoulder System when used in primary or revision reverse total shoulder arthroplasty.
- Conditions
- Osteoarthritis, Rheumatoid Arthritis, Post-traumatic Arthritis, Ununited Humeral Head Fracture
- Trial name
- NCT01480440
- Testing
- Trabecular Metal Reverse Shoulder System
- Where
- 5 sites in United States, United Kingdom
- Volunteers
- 200 people
- Sponsor
- Zimmer Biomet
Fusion of Spine (Disease), Fractures, Ununited
A Clinical Registry to Collect Patient Outcome Date for the BIOMET® Stimulator Systems
The purpose of this clinical registry is to capture data on an ongoing basis from a population of patients who will use Biomet's BHS, OrthoPak and SpinalPak devices.
- Trial name
- NCT01750840
- Testing
- Biomet® EBI Bone Healing System, Biomet Orthopak® Non-Invasive Bone Growth Stimulator System, Biomet SpinalPak® Non-Invasive Spine Fusion Stimulator
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Zimmer Biomet
Rib Fractures
Continuous Intercostal Nerve Blockade for Traumatic Rib Fractures
Rib fractures are common injuries in accident patients and can be associated with significant pain during recovery. If poorly controlled, pain from splinting due to rib fractures can result in difficulty in breathing leading to…
- Trial name
- NCT02604589
- Testing
- hydromorphone hydrochloride, Infusion catheter placement, bupivicaine 0.25%
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Anthony Iacco
Postoperative Delirium, Hip Fractures
Association Between Preoperative Hyperglycemia and Postoperative Delirium in Geriatric Hip Fracture Patients
This retrospective study aims to collect electronic medical record data from Dandong central hospital spanning from January 2013 to November 2023.
- Conditions
- Postoperative Delirium, Hip Fractures, Hyperglycemia
- Trial name
- NCT06473324
- Where
- China
- Volunteers
- 2,031 people
- Sponsor
- Wenbo Ding
Distal Radius Fracture, Pain Management
Narcotic Versus Non-narcotic Medication for Pain Management After Wrist/Hand Fractures
The purpose of this study is to evaluate two drug options for pain control in patients following wrist injury. Participants will be randomized to one of the 2 pain relief treatments to determine what treatment provides the most…
- Conditions
- Distal Radius Fracture, Pain Management, Metacarpal Fracture
- Trial name
- NCT03375593
- Testing
- Hydrocodone 5Mg/Acetaminophen 500Mg Tab, Acetaminophen 500Mg Tab, Ibuprofen 600 mg tab
- Where
- Canada
- Volunteers
- 250 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Analgesia After Fracture Femur Surgeries
Comparing Erector Spinae and Fascia Iliaca Blocks for Pain Relief After Femur Surgery.
This clinical study compares two types of nerve blocks used to control pain in adult patients undergoing surgery on the upper (proximal) or middle (midshaft) part of the femur (thigh bone).
- Trial name
- NCT06990958
- Testing
- Erector Spinae Plane Block (ESPB) group, Fascia iliaca compartment block (FICB)
- Where
- Egypt
- Volunteers
- 92 people
- Sponsor
- Cairo University