Clinical trials: Pathophysiology
Erectile Dysfunction
To Investigate the Efficacy and Safety of Vardenafil in Men With Erectile Dysfunction.
To investigate the efficacy and safety of vardenafil in men with erectile dysfunction.
- Trial name
- NCT00661115
- Testing
- Levitra (Vardenafil, BAY38-9456)
- Where
- 6 sites in India
- Volunteers
- 173 people
- Sponsor
- Bayer
Diabetes Type 2
Exercise Study on Cardiac Function in Patients With Diabetes Mellitus Type 2 and Diastolic Dysfunction
The aim of the study is to compare the effects of aerobic interval training and the IDF recommendations on physical activity on cardiac function and CV risk factors in patients with diabetes.
- Trial name
- NCT01206725
- Testing
- Exercise
- Where
- Norway
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Norwegian University of Science and Technology
Anxiety, Depression
Risk Factors of Psychiatric Disorders and Sexual Dysfunction in Infertile Men
To investigate the prevalence of psychological symptoms and sexual dysfunction, and to estimate their possible interactions in infertile men.
- Conditions
- Anxiety, Depression, Sexual Dysfunction, Infertility
- Trial name
- NCT01893216
- Where
- China
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- First Affiliated Hospital, Sun Yat-Sen University
Overweight, Obesity
Fat-Associated Cardiovascular Organ Dysfunction
This is an observational study of cardiovascular risk factors and arterial or cardiac function in subjects with overweight or obesity.
- Trial name
- FATCOR (NCT02805478)
- Testing
- There is no intervention
- Where
- Norway
- Volunteers
- 618 people, healthy volunteers welcome
- Sponsor
- Haukeland University Hospital
Right Ventricular Dysfunction
TEE 3D RV Assessment for SAVR, Mini AVR, and TAVR
Three-dimensional echocardiography has become a gold standard to assess right ventricular (RV) function, and investigators plan to use 3D transesophageal echocardiography to assess RV function in 3 types of aortic valve…
- Trial name
- NCT05804240
- Testing
- 3D TEE RVEF
- Where
- United States
- Volunteers
- 67 people
- Sponsor
- Thomas Jefferson University
Stroke
Coughing in Infratentorial Brain Lesion Patients
To record diaphragm excursion in infratentorial brain lesions patients with dysphagia during coughing and compare them to those with supratentorial brain lesion patients with dysphasia and those with no dysphagia at a university…
- Trial name
- NCT02081040
- Testing
- Not applicable (observational study with no active intervention)
- Where
- South Korea
- Volunteers
- 42 people
- Sponsor
- The Catholic University of Korea
Lung Transplant Failure
Lung PGD Biomarkers in Organ Donors
PGD is a syndrome characterized by alveolocapillary barrier structural and functional alterations with surfactant inactivation and vascular permeability increase, which cause lung edema, parenchymal infiltrate and progressive…
- Trial name
- NCT03089489
- Testing
- lung biomarkers in organ donor for PGD in lung recipient
- Volunteers
- 50 people
- Sponsor
- University Hospital of Mont-Godinne
Cognitive Impairment, Healthy Participants
Exercise-Modulated Cognitive Hormones
Investigating the influence of a 12-week exercise regimen structured thrice weekly on cognitive capacity, and related hormones like Leptin, Irisin, BDNF hormones, antioxidant status, and inflammatory cytokines, whether these…
- Trial name
- NCT07341568
- Where
- Saudi Arabia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- King Saud University
Pre-eclampsia
Oxford Luteal Dysfunction and Placental Insufficiency Study
High blood pressure (BP) affects approximately 1 in 10 pregnancies. About half of women with high blood pressure in pregnancy develop a serious complication called preeclampsia, which kills over 70,000 women and 500,000 babies…
- Trial name
- OxLuPIn (NCT07072052)
- Testing
- No intervention planned
- Where
- United Kingdom
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- University of Oxford
Mechanical Ventilation Complication, Pulmonary Edema
Systolic Function and Weaning-induced Pulmonary Edema (SystoWean Study)
The purpose of this study is to determine if the left and right ventricular systolic function is involved in the development of weaning failure related to weaning-induced pulmonary edema.
- Trial name
- SystoWean (NCT05226247)
- Testing
- Spontaneous breathing trial
- Where
- 3 sites in France
- Volunteers
- 250 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Dizziness
Is The Sudden Onset of Dizziness A Symptom of Acute Liver Dysfunction?
Dizziness is one of the most common complaints among patients admitted to the emergency department (ED). In most cases, the etiology remains unclear. Dizziness has a broad differential diagnosis.
- Trial name
- NCT02733549
- Testing
- LFTs
- Where
- Turkey (Türkiye)
- Volunteers
- 198 people, healthy volunteers welcome
- Sponsor
- Adiyaman University Research Hospital
Traumatic Brain Injury (TBI) Patients, Cognitive Impairment
Mindfulness-Integrated Neuropsychotherapy for Traumatic Brain Injury: A Mixed-Methods Evaluation of Cognitive and Psychosocial Recovery
The goal of this clinical trial is to test the effectiveness of Integrative Mindfulness Enhanced Neuropsychotherapy (IMENP) in improving neurocognitive functioning and wellbeing among adults aged 18 to 44 years with mild to…
- Conditions
- Traumatic Brain Injury (TBI) Patients, Cognitive Impairment, Depression Disorder, Fatigue Severity Scale
- Trial name
- IMENP (NCT07874685)
- Testing
- Integrative Mindfulness Enhanced Neuropsychotherapy (IMENP)
- Where
- India
- Volunteers
- 68 people
- Sponsor
- University of Madras
Paradoxical Vocal Fold Motion Disorder, Vocal Cord Dysfunction
Treatment of Paradoxical Vocal Fold Motion Disorder (PVFMD) With a Form of Respiratory Retraining Technique
Paradoxical Vocal Fold Motion Disorder (PVFMD), otherwise known as vocal cord dysfunction (VCD) is a laryngeal breathing disorder that has several potential causes. In some individuals, exertion is the predominant trigger.
- Trial name
- PVFMDRespRet (NCT02859974)
- Testing
- Respiratory retraining for PVFMD
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Boston Medical Center
Embolic Stroke, Postoperative Cognitive Dysfunction
Perfusion Pressure Cerebral Infarction Trial (PPCI)
STUDY HYPOTHESIS In cardiac surgery the volume of perioperative cerebral infarctions can be reduced by increasing mean arterial pressure (MAP) during the cardiopulmonary bypass procedure.
- Trial name
- PPCI (NCT02185885)
- Testing
- Increased bloodpressure during CPB.
- Where
- Denmark
- Volunteers
- 197 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Presbycusis, Bilateral, Alzheimer Disease 2 Due to Apoe4 Isoform
Hearing Aid and Individuals With Cognitive Disorders
This is a pilot study with the aim of evaluating the feasibility of the procedures of a future clinical trial that will help determine the impacts of hearing aid interventions on older patients with Alzheimer's Disease and…
- Conditions
- Presbycusis, Bilateral, Alzheimer Disease 2 Due to Apoe4 Isoform, Mild Cognitive Impairment
- Trial name
- NCT04049643
- Testing
- Audiologist-based fitting, Service-only Fitting, Device-only fitting
- Where
- 2 sites in United States
- Volunteers
- 17 people
- Sponsor
- Yu-Hsiang Wu
Mild Cognitive Impairment
The Effect of Blood Pressure on the Postoperative Cognitive Dysfunction
Permanent and temporary cognitive impairment in the perioperative period is of great importance to patients. Hypoperfusion due to the intraoperative hypotension is often mentioned as a possible cause of postoperative cognitive…
- Trial name
- NCT02536885
- Testing
- Liberal group, Restrictive group
- Where
- Czechia
- Volunteers
- 100 people
- Sponsor
- University Hospital Hradec Kralove
Mild Cognitive Impairment
Feasibility of Implementing Time-restricted Eating in Women With Mild Cognitive Impairment
This study will investigate the feasibility of implementing a time-restricted eating intervention in females with mild cognitive impairment.
- Trial name
- NCT05858008
- Testing
- Time-restricted eating
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Julie Pendergast
Vulvovaginal Signs and Symptoms, Genitourinary Syndrome of Menopause
Effects of Ospemifene on Brain Activation Patterns in Women With Sexual Interest-arousal Disorders
Ospemifene is the first oral and non-hormonal treatment for moderate or severe vulvo-vaginal atrophy (VVA) in postmenopausal women who are not candidates to treatment with local oestrogens.
- Conditions
- Vulvovaginal Signs and Symptoms, Genitourinary Syndrome of Menopause, Sexual; Disorder, Arousal, Female
- Trial name
- EROS (NCT04677491)
- Testing
- Ospemifene 60 mg, fMRI experiments
- Where
- Spain
- Volunteers
- 25 people
- Sponsor
- Hospital Clinic of Barcelona
Diabete Mellitus
Effectiveness of a Multimodal Cognitive Rehabilitation Protocol Combined With Mechanical Periodontal Therapy in Diabetic Patients With Cognitive Impairment
Type 2 diabetes mellitus (T2DM) is strongly associated with an increased risk of cognitive impairment via multiple, converging pathways chronic hyperglycemia, insulin resistance, and vascular injury leading to deficits in memory…
- Trial name
- NCT07870291
- Testing
- Group A, Group B, Group C
- Where
- Egypt
- Volunteers
- 105 people
- Sponsor
- Emad Eldin Mohamed
Diastolic Dysfunction
Pre-operative Focused Transthoracic Echocardiography for Prediction of Post-operative Cardiac Complications
The extent focused transthoracic echocardiography when done pre-operatively to patients admitted for elective surgery and suspected to be at risk of cardiac disease specially the geriatric population can affect perioperative…
- Trial name
- NCT04114474
- Testing
- TRANSTHORACIC ECHOCARDIOGRAPY
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- South Egypt Cancer Institute
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.