Clinical trials: Patient After Cardiac Valve Surgery
Coronary Artery Disease, Cardiac Valve Insufficiency
Study on the Clinical Performance of Steelex® Sternum Set for Sternal Closure
The study is designed as a retrospective, international, multi-center cohort study to evaluate Steelex® Sternum Set for sternum closure.
- Conditions
- Coronary Artery Disease, Cardiac Valve Insufficiency, Aortic Valve Stenosis
- Trial name
- STERCCAS (NCT05439395)
- Testing
- Sternum Closure after Cardiac Surgery
- Where
- 2 sites in Germany, Spain
- Volunteers
- 229 people
- Sponsor
- Aesculap AG
Heart Valve Diseases, Mitral Valve Insufficiency
Normal Values in Stress Echocardiographic Parameters in Patients After Successful Mitral Valve Repair for Organic MR
Surgical treatment is the only approach with potentially defined clinical success for organic mitral valve (MV) regurgitation. Recurrent or persistent complaints after initial successful MV repair is a clinical challenge in…
- Conditions
- Heart Valve Diseases, Mitral Valve Insufficiency, Heart; Dysfunction Postoperative, Cardiac Surgery, Heart; Disease, Mitral(Valve)
- Trial name
- SEP (NCT02371863)
- Where
- Netherlands
- Volunteers
- 25 people
- Sponsor
- UMC Utrecht
Frailty Syndrome, Surgery--Complications
Pre-frailty and Rehospitalization in Cardiac Surgery
Background: It has been demonstrated that pre-frailty has more adverse outcomes after cardiac surgery, however, data on prognosis and long-term evolution in pre-frailty patients after cardiac surgery without postoperative…
- Conditions
- Frailty Syndrome, Surgery--Complications, Coronary Artery Disease, Valve Anomalies
- Trial name
- NCT03949439
- Testing
- Elective Cardiac Surgery
- Where
- Brazil
- Volunteers
- 453 people
- Sponsor
- Instituto Dante Pazzanese de Cardiologia
Coronary Artery Disease, Valvular Heart Disease
Efficacy of Sternum Guard in Post Cardiac Surgery Patient
This is a single-center, single-blind, randomized parallel superiority trial comparing two groups; Sternum GuardTM as the treatment arm and Bone Wax as the active control group.
- Conditions
- Coronary Artery Disease, Valvular Heart Disease, Congenital Heart Disease in Adolescence, Post Operative Wound Infection
- Trial name
- NCT05229276
- Testing
- Sternum Guard, Bone Wax
- Where
- Indonesia
- Volunteers
- 414 people
- Sponsor
- Universitas Indonesia
Aortic Valve Regurgitation, Mitral Valve Regurgitation
Left Ventricular Reverse Remodeling Evaluation After Surgical Correction of Aortic Regurgitation
Investigators assume that surgical correction approach to functional mitral regurgitation during intervention for chronic aortic regurgitation in patients with severe enlargement of the left heart chambers influences reverse…
- Conditions
- Aortic Valve Regurgitation, Mitral Valve Regurgitation, Left Ventricle Dilated, Left Atrium Dilated
- Trial name
- ORMIX (NCT06805253)
- Testing
- Not applicable - observational study
- Where
- 2 sites in Russia
- Volunteers
- 120 people
- Sponsor
- Petrovsky National Research Centre of Surgery
Aortic Stenosis
The Effects of High Spinal Anesthesia on Heart Function, Stress Response and Pain Control in Aortic Valve Surgery
This study is looking at the effects of high spinal anesthesia (also known as total spinal anesthesia) combined with general anesthesia versus general anesthesia alone on the following: Stress response: Patients undergoing aortic…
- Trial name
- NCT00348920
- Testing
- High Spinal and General Anesthesia
- Where
- Canada
- Volunteers
- 14 people
- Sponsor
- University of Manitoba
Heart Diseases, Heart Valve Diseases
Acute Kidney Injury After Cardiac Surgery
The study aims to identify the Following: - 1. incidence and mortality of cardiac Surgery associated -AKI based on the new consensus diagnostic systems of KDIGO (Kidney Disease Improving Global Outcomes). 2.
- Conditions
- Heart Diseases, Heart Valve Diseases, Heart Shock, Cardiac Disease
- Trial name
- NCT05079724
- Testing
- Cardiac Surgery
- Volunteers
- 200 people
- Sponsor
- Assiut University
Right Ventricular (RV) Dysfunction
Temporary Biventricular Pacing
The hypothesis of this study is that temporary biventricular pacing will improve hemodynamic performance in patients with right ventricular dysfunction after open cardiac chamber cardiac surgery.
- Trial name
- BIPACE (NCT01987531)
- Testing
- left ventricular epicardial pacing lead
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- University of Pennsylvania
Myocardial Infarction, Mitral Regurgitation
Medical Versus Surgical Management of Moderate Mitral Regurgitation Following Percutaneous Coronary Intervention
The pilot prospective randomized trial is designed to determine the safety and feasibility of enrolling patients to surgically correct residual Mitral Regurgitation (MR) following Percutaneous Coronary Intervention (PCI) for…
- Trial name
- NCT01156441
- Testing
- surgical mitral valve repair w/ mitral valve annuloplasty
- Where
- United States
- Sponsor
- Southern Illinois University
Atrial Fibrillation, Post-Op Complication
Prevention of Postoperative Atrial Fibrillation (POAF) Using Intra-Pericardial Amiodarone
The purpose of this study is to evaluate the combination of CardiaMend, with the addition of amiodarone in the prevention of postoperative atrial fibrillation (POAF) in patients undergoing cardiac arterial bypass grafting (CABG)…
- Trial name
- NCT06063538
- Testing
- CardiaMend in Combination with Amiodarone
- Where
- United States
- Volunteers
- 63 people
- Sponsor
- University of Chicago
Aortic Stenosis
Reactive Oxygen Species Following Aortic Valve Replacement
Surgical aortic valve replacement (SVAR) is currently the 'Gold Standard' therapy for patients with severe symptomatic aortic stenosis (AS).
- Trial name
- ROS (NCT02841917)
- Where
- United Kingdom
- Volunteers
- 3 people
- Sponsor
- University Hospital Southampton NHS Foundation Trust
Stellate Ganglion Block, Heart Valve Replacement (Mechanical or Biological With AF)
Effect of Ultrasound-guided Left Stellate Ganglion Block on Rapid Recovery of Patients Undergoing Cardiac Valve Replacement and Its Mechanism
In this study, Valve replacement patients undergoing cardiopulmonary bypass were randomly divided into control group and experimental group (SGB Group) , main outcome measures: postoperative complications (pulmonary infection…
- Trial name
- NCT05587023
- Testing
- stellate ganglion block
- Where
- China
- Volunteers
- 62 people
- Sponsor
- Zhonghua Chen,MD
Acute Myocardial Infarction, Disorder; Heart, Functional, Postoperative, Cardiac Surgery
High-sensitivity Troponin T in Acute Myocardial Infarction After Cardiac Valvular Surgery
A measurable degree of heart muscle tissue injury is expected in patients undergoing heart valvular surgery. The level of this injury can be measured by cardiac biomarkers in blood samples.
- Conditions
- Acute Myocardial Infarction, Disorder; Heart, Functional, Postoperative, Cardiac Surgery, Myocardial Infarction, Heart Valve Diseases
- Trial name
- NCT02518282
- Testing
- Serum levels of high-sensitivity troponin T, Twelve-lead ECGs, Transthoracic echocardiography (TTE)
- Where
- Spain
- Volunteers
- 800 people
- Sponsor
- University of Valladolid
Mitral Valve Replacement
Comparative Effects of MIIT With CT In Post-MVR Surgery Patients
Mitral Valve Replacement (MVR) surgery is commonly performed to treat patients with severe mitral valve diseases, such as mitral stenosis or regurgitation.
- Trial name
- NCT07438717
- Testing
- Moderate-Intensity Interval Training (MIIT), Moderate-Intensity Continuous Training (MICT)
- Where
- Pakistan
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Hemorrhage
Tranexamic Acid, Hemorrhage and Transfusions After Combined Aortic Valve Replacement and Coronary Artery Bypass Surgery.
In this study we will investigate whether tranexamic acid given as an intravenous bolus injection before start of surgery, followed by a continuous infusion during surgery reduces, perioperative hemostatic activation, and…
- Trial name
- NCT00375466
- Testing
- Tranexamic acid
- Where
- Norway
- Volunteers
- 63 people
- Sponsor
- St. Olavs Hospital
Elderly Heart Valve Surgery, Silent Aspiration
Study on Influencing Factors and Intervention of Silent Aspiration After Heart Valve Operation in Elderly Patients
Objective To investigate the safety and effectiveness of interference electrical stimulation in the prevention of silent aspiration after heart valve surgery in elderly patients.
- Trial name
- SILENT-HV (NCT07710001)
- Testing
- The intervention was delivered using the Gentle Stim Electrical Stimulation Therapy Device (Model: JC-2071), Usual Care Group
- Where
- China
- Volunteers
- 117 people
- Sponsor
- Fujian Medical University Union Hospital
Post Operative Atrial Fibrillation
Prevention of Post-OP AFib Using Combination of CardiaMend and Amiodarone
The purpose of this study is to evaluate the combination of CardiaMend, with the addition of amiodarone in the prevention of postoperative atrial fibrillation (POAF) in patients undergoing isolated cardiac arterial bypass…
- Trial name
- CAMP POAF (NCT05681182)
- Testing
- CardiaMend with the Addition of Amiodarone
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- WakeMed Health and Hospitals
Coronary Artery Bypass Grafting, Heart Diseases
The Short Form-36: Pre- Versus Post-Surgical Administration in Cardiac Surgery Patients
The purpose of this study is to determine whether the SF-36 can be administered reliably to cardiac surgery patients (two to three days) post-surgery, with the patient answering the questions of this survey from a pre-surgical…
- Conditions
- Coronary Artery Bypass Grafting, Heart Diseases, Heart Valve Diseases
- Trial name
- NCT00226265
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Weill Medical College of Cornell University
Heart Valve Diseases
PMS Promotes the Recovery of Patients After Heart Valve Replacement
Acute gastrointestinal injury (AGI) is related to poor outcomes in patients after heart valve replacement. The purpose of this study is to evaluate the effect of the probiotic mixture supplementation (PMS) in patients after heart…
- Trial name
- PMS (NCT05498948)
- Testing
- Probiotic mixture
- Where
- China
- Volunteers
- 52 people
- Sponsor
- Hepatopancreatobiliary Surgery Institute of Gansu Province
Mechanical Aortic and/or Mitral Valve Replacement Operation
Patient International Normalised Ratio (INR) Self-Testing Program
The aims of the study are to prove correlation between laboratory and patient self-testing (PST) measurements, estimation of INR variability within a target therapeutic zone and frequency of hemorrhagic and/or thromboembolic…
- Trial name
- NCT00925197
- Testing
- INR self-testing program
- Volunteers
- 206 people
- Sponsor
- University Hospital, Clermont-Ferrand