Clinical trials: Patient Care Planning
Glioblastoma Multiforme, Anaplastic Astrocytoma
The Toca 5 Trial: Toca 511 & Toca FC Versus Standard of Care in Patients With Recurrent High Grade Glioma
This is a multicenter, randomized, open-label phase 2/3 study of Toca 511 and Toca FC versus standard of care that comprises Investigator's choice of single agent chemotherapy (lomustine or temozolomide) or bevacizumab…
- Trial name
- Toca5 (NCT02414165)
- Testing
- Toca 511, Toca FC, Lomustine
- Where
- 67 sites in United States, Canada and 2 more
- Volunteers
- 403 people
- Sponsor
- Tocagen Inc.
Dental Caries
Everybody Brush: A Community-wide Toothpaste Distribution Campaign
Dental caries (tooth decay) is a disease with significant public health implications afflicting low-income children, with marked rural disparities in disease prevalence and treatment.
- Trial name
- NCT02327507
- Testing
- Toothpaste & Telephone Support
- Where
- United States
- Volunteers
- 21,731 people
- Sponsor
- Advantage Dental Services, LLC
Obstructive Sleep Apnoea Syndrome (OSAS)
Evaluate the Benefit of an Individualised Treatment Plan (VitalCare) VS SOC in OSA Patients Treated With CPAP/APAP
According to a stratification procedure, the objective of a personalised care plan (VitalCare) is to identify points for improvement since the early stage of the patient's pathway of CPAP/APAP treatment and to adjust patient…
- Trial name
- VitalCare (NCT05246449)
- Testing
- individualised treatment plan (VitalCare) and associated remote medical monitoring
- Where
- Portugal
- Volunteers
- 113 people
- Sponsor
- Air Liquide Santé International
Suicidal Ideation
Virtual Training Role-Plays to Improve Patient Suicide Outcomes in Primary Care Settings
SIMmersion, in collaboration with the Institute for Family Health (IFH) and the Educational Development Center (EDC) propose to develop a web-based training product, Suicide Prevention Role-plays for Interactive Training…
- Trial name
- NCT03207217
- Testing
- Web-based training Product
- Volunteers
- 91 people, healthy volunteers welcome
- Sponsor
- SIMmersion, LLC
Cancer
Shared Decision Making in Pain Management Planning in Patients With Cancer
The goal of this project is to evaluate the effectiveness of shared-decision-making (SDM) to manage chronic and breakthrough pain in patients with cancer.
- Trial name
- NCT03304145
- Testing
- The Carevive CPS
- Where
- United States
- Volunteers
- 105 people
- Sponsor
- Carevive Systems, Inc.
Quality of Health Care, Patient Safety
CITE: Clinical Inference Tethered to Evidence - a Retrieve-and-verify Layer for AI Care Plans
This trial evaluates CITE, a retrieve-and-verify layer that audits an AI-generated care plan against a full-text evidence corpus and flags patient-specific codifiable safety hazards to the clinician.
- Conditions
- Quality of Health Care, Patient Safety, Clinical Decision Support
- Trial name
- CITE (NCT07718893)
- Testing
- CITE evidence-grounding retrieve-and-verify layer, AI care plan with safety guardrails
- Where
- United States
- Volunteers
- 240 people
- Sponsor
- Waymark
COPD, Healthy Smoker
SLP Model Development in the Diagnosis of COPD Patients
This is an observational, comparative, multicentre study to develop a model for the Thora3Di™ against standard practice in patients who are undergoing investigation for COPD.
- Trial name
- SLPCOPD (NCT04584801)
- Testing
- Structured Light Plethysmography
- Where
- 7 sites in United Kingdom
- Volunteers
- 201 people, healthy volunteers welcome
- Sponsor
- Pneumacare Ltd
Multiple Myeloma
Improving the Quality of Multiple Myeloma Treatment With Patient Care Plans
The overarching objective of this study is to evaluate the symptom assessment and management behaviors used by multiple myeloma (MM) providers for alignment with evidence-based practices, and to explore changes in these symptom…
- Trial name
- NCT03046329
- Testing
- Carevive CPS
- Volunteers
- 90 people
- Sponsor
- Carevive Systems, Inc.
Blood Loss, Surgical, Coagulation Disorder
Phase 3 Trial of Reltodecacog Alfa (VMX-C001) vs Usual Pharmacological Care in Patients Taking a FXa Direct Oral Anticoagulant Who Require Urgent Surgery With or Without Heparin.
The goal of this clinical trial is to learn if reltodecacog alfa (VMX-C001) works to to allow blood clotting control in participants who take FXa Direct Oral Anticoagulants (DOACs) during surgery or other invasive procedures that…
- Trial name
- EQUILIBRIX-S (NCT07288489)
- Testing
- Reltodecacog alfa, Usual Pharmacological Care
- Where
- 77 sites in United States, Australia and 16 more
- Volunteers
- 800 people
- Sponsor
- VarmX B.V.
Breast Cancer
Improving Surgical/Medical Oncology Collaboration for Breast Cancer Treatment Planning: Pilot Testing the Impact of Continuing Education and Patient Care Planning
This study will explore provider's screening and management practices for eligibility for neoadjuvant therapy from baseline to following the project intervention (use of a novel existing technology, the Carevive Care Planning…
- Trial name
- NCT03161600
- Testing
- Carevive CPS
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Carevive Systems, Inc.
Glioblastoma, Recurrent Glioblastoma
Sonocloud-9 in Association With Carboplatin Versus Standard-of-Care Chemotherapies (CCNU or TMZ) in Recurrent GBM
The brain is protected from any toxic or inflammatory molecule by the blood-brain barrier (BBB). This physical barrier is located at the level of the blood vessel walls.
- Conditions
- Glioblastoma, Recurrent Glioblastoma, GBM
- Trial name
- SONOBIRD (NCT05902169)
- Testing
- SonoCloud-9 (SC9), Carboplatin, Lomustine
- Where
- 56 sites in United States, Austria and 9 more
- Volunteers
- 560 people
- Sponsor
- CarThera
Multiple Myeloma
A Study to Evaluate Subcutaneous TAK-079 Added to Standard of Care Regimens in Participants With Newly Diagnosed Multiple Myeloma (NDMM)
The purpose of this original study is to determine the recommended phase 2 dose (RP2D) of TAK-079 when administered to participants with NDMM in combination with the backbone treatment regimen.
- Trial name
- NCT03984097
- Testing
- TAK-079, Lenalidomide, Dexamethasone
- Where
- 9 sites in United States
- Volunteers
- 50 people
- Sponsor
- Takeda