Clinical trials: Patient Cataract
Cataracts
Aqueous Absorption and Pharmacokinetics of Besivance Versus VIGAMOX in Patients Undergoing Phacoemulsification
The purpose of this study is to compare drug concentrations in aqueous humor following ocular instillation of Besivance and VIGAMOX in subjects undergoing cataract surgery.
- Trial name
- NCT01296191
- Testing
- Moxifloxacin, besifloxacin
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Frank A. Bucci, Jr., M.D.
Cataract
Evaluation of Aqueous Humor DEL-1 and IL-17 Levels in Diabetic Cataract Patients
By comparing DEL-1 and IL-17 levels in the aqueous humor of diabetic cataract patients with the aqueous humor of non-diabetic patients, we aim to understand the biochemical effects of diabetes-related inflammatory processes in…
- Trial name
- DEL-1 and IL-1 (NCT06995131)
- Testing
- Observational Study Procedure
- Where
- Turkey (Türkiye)
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Uşak University
Primary Open Angle Glaucoma, Pseudoexfoliative Glaucoma
Comparing Hydrus Microstent(TM) to the iStent for Lowering IOP in Glaucoma Patients Undergoing Cataract Surgery
This clinical trial compares two implantable devices intended to lower the pressure inside the eye of glaucoma patients. One of the two devices will be implanted immediately following cataract surgery and the placement of a…
- Conditions
- Primary Open Angle Glaucoma, Pseudoexfoliative Glaucoma, Pigmentary Dispersion Glaucoma
- Trial name
- NCT02024464
- Testing
- Hydrus Microstent, iStent Trabecular Micro Bypass, Cataract removal and intraocular lens (IOL) implantation
- Volunteers
- 306 people
- Sponsor
- Ivantis, Inc.
Cataract Surgery
A Prospective Multicenter Study To Assess The Clinical Outcomes Of Current Phacoemulsification Approach To Cataract Extraction Versus The Micor System Device
The purpose of this research study is to evaluate the clinical outcomes of current phacoemulsification approaches to cataract extraction involving high-frequency thermogenic energy versus the use of the MICOR System device using…
- Trial name
- NCT05729477
- Testing
- miCOR System, Phaco Subject Cohort
- Where
- 6 sites in United States
- Volunteers
- 402 people, healthy volunteers welcome
- Sponsor
- Carl Zeiss Meditec, Inc.
Cataract, Lenses, Intraocular
Effect of Intraocular Lens (IOL) Centration and Tilt on Visual Performance With Clareon® Vivity® IOL Implantation
The goal of this observational study is to assess the effect of intraocular lens (IOL) movement in patients who have undergone Clareon® Vivity® IOL implantation.
- Trial name
- NCT05827133
- Testing
- No intervention
- Where
- United States
- Volunteers
- 101 people
- Sponsor
- East Coast Institute for Research
Cataract, Presbyopia
Monofocal IOL Visual Outcomes When Targeting Mini Monovision
This study is a 3-month, prospective, up to 2 center, bilateral, randomized subject masked clinical evaluation of a monofocal intraocular lens (IOL) when both eyes are targeted for emmetropia and when the non-dominant eye is…
- Trial name
- NCT05069415
- Testing
- Eyhance IOL
- Where
- 2 sites in United States
- Volunteers
- 75 people
- Sponsor
- Carolina Eyecare Physicians, LLC
Dry Eye Disease, Meibomian Gland Dysfunction
Preoperative iLux on Cataract Surgery Derived Dry Eye Disease Due to Meibomian Gland Dysfunction
This prospective study will investigate the effect of pre-operative Systane iLux system administration in treated cataract induced dry eye disease.
- Conditions
- Dry Eye Disease, Meibomian Gland Dysfunction, Cataract Senile, Dry Eye Syndromes
- Trial name
- NCT06483750
- Testing
- Systane iLux Treatment
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- George Washington University
Ocular Inflammation
Efficacy and Safety Study of IBI-10090 in Cataract Surgery Patients
This study will test the efficacy and safety of IBI-10090 in the treatment of ocular inflammation after cataract surgery.
- Trial name
- NCT01214174
- Testing
- IBI-10090
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- ICON Bioscience Inc
Primary Open-angle Glaucoma, Cataract
Post Approval Study of the CyPass System
The purpose of this study is to demonstrate that the rate of clinically relevant complications associated with CyPass Micro-Stent placement and stability using the CyPass 241-S applier, as determined at 36 months in the…
- Trial name
- NCT03273907
- Testing
- CyPass Micro-Stent implanted with CyPass 241-S applier, Cataract surgery
- Where
- 20 sites in United States
- Volunteers
- 79 people
- Sponsor
- Alcon Research
Cataract
Patient Perception of Visual Quality and Function
The purpose of this study is to evaluate the visual quality and function of pseudophakic patients.
- Trial name
- NCT02146599
- Testing
- Administration of patient self-assessment
- Where
- United States
- Volunteers
- 301 people, healthy volunteers welcome
- Sponsor
- Abbott Medical Optics
Disorders of the Eye Following Cataract Surgery
Microbiological Evaluation of the Ocular Flora Before Cataract Surgery
The purpose of the present study is to elucidate the spectrum of ocular flora and their antimicrobial susceptibility profiles in patients undergoing routine cataract surgery.
- Trial name
- NCT02124603
- Where
- Italy
- Volunteers
- 120 people
- Sponsor
- SIFI SpA
Cataract
Evaluation Of Aqueous Humor Of Levofloxacin-Dexamethasone Eye Drops And Of Its Components In Patients Undergoing Cataract Surgery
The purpose of this study is to evaluate the penetration of levofloxacin and dexamethasone 21-phosphate into the aqueous humour after ocular administration in combination or as single active ingredients.
- Trial name
- iPERME (NCT03740659)
- Testing
- Levofloxacin + Dexamethasone, Levofloxacin, Dexamethasone
- Where
- 2 sites in Italy
- Volunteers
- 125 people
- Sponsor
- NTC srl
Cataract
Safety and Efficacy of Iontophoretic Dexamethasone Phosphate Delivery Prior to Implantation of a Posterior Chamber IOL
The purpose of this study is to evaluate the safety and efficacy of ocular iontophoresis with dexamethasone phosphate ophthalmic solution EGP-437 using the EyeGate® II Drug Delivery System (EGDS) compared to placebo in patients…
- Trial name
- NCT01602068
- Testing
- Dexamethasone Phosphate Ophthalmic, 100 mM Sodium Citrate Buffer
- Where
- 3 sites in United States
- Volunteers
- 45 people
- Sponsor
- Eyegate Pharmaceuticals, Inc.
Macular Edema
A Clinical Safety and Efficacy Comparison of NEVANAC 0.1% to Vehicle After Cataract Surgery in Diabetic Retinopathy Patients
The purpose of this study is to determine whether nepafenac is safe and effective for reducing the incidence of macular edema following cataract surgery in diabetic retinopathy patients.
- Trial name
- NCT00782717
- Testing
- Nepafenac ophthalmic suspension, 0.1% (NEVANAC), Nepafenac ophthalmic suspension vehicle, Prednisolone acetate ophthalmic suspension (OMNIPRED)
- Volunteers
- 263 people
- Sponsor
- Alcon Research
Dry Eye Syndromes
Clinical Effects and Safety of 3% Diquafosol After Cataract Surgery
The purpose of this study is determine whether 3% diquafosol and 0.1% sodium hyaluronate are effective and safe in the treatment of patients with dry eye after cataract surgery.
- Trial name
- NCT02608489
- Testing
- Diquafosol (Diquas), Sodium Hyaluronate (Hyalein)
- Volunteers
- 86 people
- Sponsor
- Soonchunhyang University Hospital
Primary Open Angle Glaucoma (POAG)
Safety and Performance Study of the ARGOS-IO (Intraocular) System in Patients With Primary Open Angle Glaucoma (POAG)
The purpose of this study is to evaluate the safety and performance of the ARGOS-IO system in patients with POAG and indicated cataract surgery.
- Trial name
- NCT02434692
- Testing
- ARGOS-IO system
- Where
- 11 sites in Germany
- Volunteers
- 24 people
- Sponsor
- Implandata Ophthalmic Products GmbH
Cataracts
A Clinical Outcome Study of Two Multifocal Intraocular Lenses (IOL) in Cataract Patients
The purpose of this study is to compare AcrySof® IQ ReSTOR® +2.5 D Multifocal IOL in both eyes (bilateral implantation) to AcrySof® IQ ReSTOR® +2.5 D Multifocal IOL in the dominant eye with AcrySof® IQ ReSTOR® +3.0 D Multifocal…
- Trial name
- NCT01684007
- Testing
- AcrySof® IQ ReSTOR® +2.5 D Multifocal IOL Model SN6AD2 [SV25T0], AcrySof® IQ ReSTOR® +3.0 D Multifocal IOL Model SN6AD1
- Volunteers
- 112 people
- Sponsor
- Alcon Research
Cataract
Pharmacokinetic Evaluation of Moxifloxacin in Vigadexa® in Aqueous Humor Samples Following Preoperative Antibiotic/Steroid Dosing in Cataract Surgery Patients
The purpose of this study was to determine the moxifloxacin aqueous penetration when dosing with a combination drug Vigadexa preoperatively in cataract patients.
- Trial name
- NCT01859702
- Testing
- Moxifloxacin 0.5%/Dexamethasone 0.1% ophthalmic solution
- Volunteers
- 36 people
- Sponsor
- Alcon Research
Primary Open-angle Glaucoma
Long-term Safety and Performance of the ARGOS-IO Intraocular Pressure Sensor System in Subjects With Primary Open Angle Glaucoma (POAG)
The purpose of this study is to evaluate the long-term safety and performance of the ARGOS-IO system in patients with Primary Open Angle Glaucoma (POAG)
- Trial name
- NCT03651336
- Testing
- ARGOS-IO Sensor Pressure System
- Where
- 4 sites in Germany
- Volunteers
- 16 people
- Sponsor
- Implandata Ophthalmic Products GmbH
DIABETIC MACULAR EDEMA
Triamcinolone vs. Laser for Diabetic Macular Edema
The purpose of this study is to determine if intravitreal triamcinolone acetonide (IVTA) injection at the time of cataract surgery will improve visual acuity and decrease post-operative swelling in diabetic patients requiring…
- Trial name
- IVTA (NCT00229931)
- Testing
- Triamcinolone acetonide, laser
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- University of Oklahoma