Clinical trials: Patient Controlled Analgesia
Orthopaedic Surgery
Remote Controlled Analgesia on Patient Experience
The main objective of this study is to compare the efficacy of continuous nerve blocks with single injection in terms of perioperative patient satisfaction after scheduled orthopedic ambulatory surgery.
- Trial name
- R-CAPE (NCT02720965)
- Testing
- Remote-controlled perineural local anesthetics delivery
- Where
- France
- Volunteers
- 300 people
- Sponsor
- University Hospital, Montpellier
Labor Onset and Length Abnormalities
Goal-directed Labor Epidural Analgesia Maintenance
The GLEAM trial is a multicenter, pragmatic, cluster-randomized trial to assess the effects of programmed intermittent epidural bolus versus continuous epidural infusion on the rate of spontaneous vaginal delivery and several…
- Trial name
- GLEAM (NCT05255263)
- Testing
- PIEB, CEI
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Chronic Low-back Pain
Cognitive Functional Therapy Compared With Sham-treatment for Low Back Pain
Chronic low back pain is a public health problem, and there is strong evidence that it is associated with a complex interaction of biopsychosocial factors.
- Trial name
- NCT04518891
- Testing
- Cognitive Functional Therapy (CFT)
- Where
- Brazil
- Volunteers
- 152 people
- Sponsor
- University of Sao Paulo
HSAN Type IV
A Study of Norepinephrine in Patients With Congenital Insensitivity to Pain and Anhidrosis
The aim of this study is to increase norepinephrine levels in a population of young adults where NE levels are very low or undetectable. In order to achieve this, the optimal dose will be determined in a titration step.
- Trial name
- NCT02624310
- Testing
- Droxidopa (L-DOPS)
- Sponsor
- NYU Langone Health
Labor Pain, Pain
The Effects of Intermittent Epidural Bolus on Fever During Labor Analgesia
Epidural analgesia is associated with maternal intra-partum fever during labor. Intermittent epidural injections appear to reduce the incidence of maternal intra-partum fever compared to continuous epidural infusion during labor…
- Conditions
- Labor Pain, Pain, Neurologic Manifestations, Signs and Symptoms
- Trial name
- EIEBFLA (NCT01708668)
- Testing
- Epidural analgesia, Combined spinal-epidural analgesia, Continuous epidural infusion
- Where
- China
- Volunteers
- 12,000 people
- Sponsor
- ShanWu Feng, M.D.
Pain, Pain, Postoperative
Patient Controlled Administration of Liquid Acetaminophen
This is a proof of concept pilot study investigating the feasibility and acceptability of patient controlled oral medication administration, using the commonly used and low risk medication in the hospital, oral acetaminophen.
- Trial name
- NCT06498713
- Testing
- Acetaminophen 650 mg Oral Tablet, Acetaminophen 650mg Liquid, CADD pump
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Yale University
Postoperative Pain, Wisdom Tooth
Protective Analgesia for Postoperative Pain Relief Following Day Case Oral Surgery
The purpose of this study is to investigate whether robust analgesic regime (protective analgesia) can improve postoperative pain experience for patients undergoing lower wisdom teeth extraction under day case general anaesthetic.
- Trial name
- NCT00895843
- Testing
- Brufen retard, ibuprofen, Bupivacaine
- Where
- 2 sites in United Kingdom
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- University of Manchester
for Post-operative Pain Relief in Spine Surgeries
Low Dose Perioperative Ketamine Infusion and it's Effect on Postoperative Pain Score, Sedation Score and Narcotic Consumption in Patients Undergoing Spine Surgery: A Prospective Randomized Double Blind Control Trial.
Low dose perioperative ketamine infusion and it's effect on postoperative pain score, sedation score and narcotic consumption in patients undergoing spine surgery: A prospective randomized double blind control trial.
- Trial name
- NCT04259476
- Testing
- Ketamine Hydrochloride
- Where
- Pakistan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Services Institute of Medical Sciences, Pakistan
Pancreatitis, Chronic
Surgical Outcome and Differences on Histopathology in Patients With Alcoholic & Non Alcoholic Chronic Pancreatitis
Numerous treatment modalities have been proposed to treat pain in alcoholic and non-alcoholic chronic pancreatitis such as analgesic medication, inhibition of gastric acid production, enzyme substitution, somatostatin analogues…
- Trial name
- NCT02048267
- Testing
- Frey's procedure/Pylorus preserving pancreatoduodenectomy
- Where
- India
- Volunteers
- 24 people
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
Lung Diseases, Lung Cancer
SPSIPB vs SAPB for Thoracoscopic Surgery
Video-assisted thoracic surgery (VATS) has recently been evaluated as the standard surgical procedure for lung surgery. Although VATS is less painful than thoracotomy, patients may feel severe pain during the first hours of the…
- Conditions
- Lung Diseases, Lung Cancer, Lung Neoplasms, Lung Cancer Metastatic
- Trial name
- NCT06546839
- Testing
- SPSIPB blcok, SAPB block, Postoperative analgesia management
- Where
- Turkey (Türkiye)
- Volunteers
- 46 people
- Sponsor
- Medipol University
Pelvic Organ Prolapse
Intraperitoneal Bupivacaine for Pelvic Organ Prolapse
The purpose of this study is to evaluate the effects of 30 mL intraperitoneal Bupivacaine without epinephrine 0.25% on postoperative pain control in patients undergoing pelvic organ prolapse repair.
- Trial name
- NCT06120530
- Testing
- Bupivacaine, Saline
- Where
- United States
- Volunteers
- 91 people
- Sponsor
- Indiana University
Total Hip Replacement
Effectiveness of Patient-Controlled Intravenous Analgesia (PCIA) With Fentanyl
To enhance post-operative pain management, patient-controlled intravenous analgesia (PCIA) has been employed. The fentanyl background PCIA therapy was created to solve the limitations of IV-based PCIA, such as programming errors…
- Trial name
- NCT05429567
- Testing
- Fentanyl
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Egymedicalpedia
Total Shoulder Arthroplasty, Reverse Total Shoulder Arthroplasty
Continuous Interscalene Blocks and Rebound Pain
The primary objectives of this present study are to examine whether a continuous interscalene block of a total duration of 48 hours reduces the incidence of rebound pain comparatively to single-shot interscalene block, through…
- Conditions
- Total Shoulder Arthroplasty, Reverse Total Shoulder Arthroplasty, Interscalene Analgesia, Interscalene Blocks
- Trial name
- NCT07770165
- Testing
- Continuous interscalene nerve block, Interscalene Block
- Where
- Canada
- Volunteers
- 154 people
- Sponsor
- University of Calgary
Pain Management, Postoperative Care
The Effect of the Strategic Game Tangram on Postoperative Patient Outcomes
The aim of this study was to investigate the effects of playing tangram game after surgery on pain, fatigue and comfort levels in patients undergoing abdominal surgery.
- Conditions
- Pain Management, Postoperative Care, Nursing Care
- Trial name
- NCT07031271
- Testing
- Tangram game
- Where
- Turkey (Türkiye)
- Volunteers
- 74 people
- Sponsor
- Aydin Adnan Menderes University
Postoperative Pain After Video Assisted Thoracic Surgery
Analgesic Effect of Intravenous Patient-Controlled Analgesia (IV PCA) Versus Paravertebral Block After Video Assisted Thoracic Surgery (VATS)
The purpose of this study is to compare the analgesic effect of paravertebral block with that of intravenous patient-controlled analgesia after video assisted thoracic surgery.
- Trial name
- NCT01538914
- Testing
- paravertebral block, PCA
- Where
- South Korea
- Volunteers
- 76 people
- Sponsor
- Seoul National University Hospital
Pain, Postoperative
Efficacy Study of Rectus Sheath Block to Control Postoperative Pain
The aim of this study is to evaluate the effect of the ultrasound guided rectus sheath block (RSB) on both intraoperative sevoflurane consumption and postoperative analgesia.
- Trial name
- UGRSB (NCT02115087)
- Testing
- ultrasound guided rectus sheath block, Morphine
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Cukurova University
Rectus Abdominis and External Oblique Muscle Infiltration Analgesia
Costal Cartilage Donor-site Pain: Does Abdominal Muscle Infiltration Analgesia Work?
Donor-site pain is an adverse effect of autologous ear reconstruction. A well-planned pain management protocol is needed. The objective of this study was to introduce rectus abdominis and external oblique muscle infiltration…
- Trial name
- NCT06118216
- Testing
- rectus abdominis(RAM) and external oblique muscle(EOM) infiltration analgesia, intravenous patient-controlled anesthesia
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Xiaohui Su
Analgesic Quality, Mobility
Observational Study of Analgesia and Cost-efficiency of Analgetic Medication Pumps (Zalviso and PCA-syringe Pump (PCA=Patient Controlled Analgesia)) After Urogenital Intervention at the Clinical Daily Routine
The observational study will check if there is a difference in the postoperative care of patients with urogenital intervention while using the standard PCA-syringe pump or using the Zalviso sufentanyl sublingual analgetic system.
- Trial name
- NCT03355352
- Testing
- Sufentanil
- Where
- Germany
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University Hospital Tuebingen
Pain Management, Orthopedic Procedure Pain
The Analgesic Efficacy of Nefopam in Orthopedics Surgery
Pain-free and relief are one of the anesthesiologist's most important concerns during the operation. General aim is always to effectively control pain but while simultaneously reducing opioid requirements to reduce opioid related…
- Trial name
- NCT06680609
- Testing
- Nefopam 20 MG/ML
- Where
- Jordan
- Volunteers
- 49 people
- Sponsor
- King Abdullah University Hospital
Opioid Analgesia
Pharmacokinetics and Safety of ORF Tablets in Pediatric Patients
The purpose of this study is to characterize the pharmacokinetics (PK) of single-dose ORF tablets in pediatric patients aged 6 to 16 years, inclusive.
- Trial name
- NCT01160614
- Testing
- Oxycodone hydrochloride controlled-release (ORF) tablets
- Where
- 17 sites in United States, Australia and 2 more
- Volunteers
- 30 people
- Sponsor
- Purdue Pharma LP