Clinical trials: Patient Refusal of Treatment
HIV, HIV Infections
Evaluation of Effectiveness of Pharmaceutical Care on the Adherence of HIV-Positive Patients to Antiretroviral Therapy
INTRODUCTION: Studies prove that the pharmaceutical care (PC) increases the adherence to the antiretroviral; thus, they increase the undetectable viral load.
- Trial name
- PC-HIV (NCT00959361)
- Testing
- pharmaceutical care
- Where
- Brazil
- Volunteers
- 332 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Adherence, Treatment, Health Literacy
Sociological Determinants of Positive Airway Pressure Adherence in OSA Patients
Multicentric, prospective, opened study to evaluate the impact of Health Literacy Levels on CPAP withdrawal in Obstructive Sleep Apnea patients within 6 months of inclusion.
- Conditions
- Adherence, Treatment, Health Literacy, Obstructive Sleep Apnea
- Trial name
- SOCIO-SAS (NCT05385302)
- Where
- 2 sites in France
- Volunteers
- 250 people
- Sponsor
- University Hospital, Grenoble
Pneumococcal Vaccine Uptake, Vaccination Willingness
PRomoting Older Adults' Pneumococcal Vaccination Through Education and Learning
The goal of this trial is to compare the effect of a web-based educational video about pneumococcal vaccines and a reminder email to get vaccinated (intervention) with a reminder email alone (comparator) in adults aged 65 or…
- Conditions
- Pneumococcal Vaccine Uptake, Vaccination Willingness, Pneumococcal Vaccine Knowledge, Pneumococcal Vaccine Attitude
- Trial name
- PROPEL (NCT06234683)
- Testing
- Web-based educational video on pneumococcal vaccination, Reminder email to be vaccinated
- Where
- Canada
- Volunteers
- 720 people, healthy volunteers welcome
- Sponsor
- University of Ottawa
Cardiovascular Disease
Study of an Intervention to Improve Use of Life-saving Medications for Heart Disease
The purpose of this study is to evaluate the effectiveness of a program to help patients with heart disease stay on their heart medications.
- Trial name
- PILOT-EBM (NCT00323258)
- Testing
- oral education & written tips for remembering medications, pill box, pocket medication card
- Where
- United States
- Volunteers
- 143 people
- Sponsor
- Duke University
Chronic Respiratory Failure, Tracheostomy Complication
Parental Perception of COVID-19 Vaccine in Technology Dependent Patients
This study involves conducting a telephonic or in person survey regarding parental perception and attitudes about vaccinating the respective "technology dependent" child with the COVID 19 vaccination.
- Conditions
- Chronic Respiratory Failure, Tracheostomy Complication, Mechanical Ventilation Complication
- Trial name
- NCT05084976
- Testing
- COVID 19 vaccine counseling
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Northwell Health
Vaccine Refusal, Vaccine-Preventable Diseases
Improving Vaccine Counseling Skills Among Residents Using Educational Modules and Standardized Patient Encounters
Unfortunately, only 40% of US pediatric residency programs reported in a survey that vaccine safety and counseling training is provided to residents.
- Conditions
- Vaccine Refusal, Vaccine-Preventable Diseases, Physician-Patient Relations
- Trial name
- NCT06074237
- Testing
- Immersive resident education, Standardized patient (SP) encounter
- Where
- United States
- Volunteers
- 112 people
- Sponsor
- Corewell Health East
HPV Vaccination, Vaccine; Uptake
PREVENT HPV-Related Cancers - BootCamp Translation
This study will serve as one of the first to develop and test the effectiveness of strategies to promote HPV vaccination among diverse rural parents and caregivers of children ages 9-17 years in the Mountain West.
- Conditions
- HPV Vaccination, Vaccine; Uptake, Vaccination; Series Completion
- Trial name
- PREVENT (NCT06290206)
- Testing
- PREVENT - BCT
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of Utah
Acute Coronary Syndrome, Heart Failure
Intrahospital Influenza Vaccination in Patients at High Cardiovascular Risk (VACC-UP)
The aim of this study is to evaluate the effect of offering intrahospital influenza vaccination as an adjunct to active counseling during the index hospitalization to adult patients hospitalized for acute coronary syndrome (ACS)…
- Conditions
- Acute Coronary Syndrome, Heart Failure, Influenza, Human, Cardiovascular Diseases
- Trial name
- VACC-UP (NCT07721649)
- Testing
- Intrahospital seasonal influenza vaccination offer, Standardized active influenza vaccination counseling, Standard of care discharge recommendation for ambulatory vaccination
- Where
- 2 sites in Germany
- Volunteers
- 482 people
- Sponsor
- Stephan Baldus
Decision Making, Life Experiences
Health Research Participation: Experiences and Decisions of Military Members
The purpose of the study is to describe service members' experiences as participants in health research, including their reasons for deciding for or against research participation.
- Trial name
- NCT02518893
- Testing
- Demographic Data, Interview
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Washington
Vaccine Hesitancy, COVID-19 Testing
A CHW Intervention to Identify and Decrease Barriers to COVID 19 Testing & Vaccination
The objective of this study is to compare the results of a COVID-19 specific curriculum led by LACDHS Community Health Workers (CHWs) from these same communities of safety-net patients to effectively increase COVID-19 testing and…
- Conditions
- Vaccine Hesitancy, COVID-19 Testing, Community Health Workers
- Trial name
- NCT05473936
- Testing
- Community Health Worker led curriculum
- Where
- 2 sites in United States
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Charles Drew University of Medicine and Science
Bipolar Disorder
Customized Medication Adherence Enhancement for Treating Adults With Bipolar Disorder
In this study, patients with bipolar disorder who do not take their medications as prescribed will receive specialized education and therapy treatment to determine whether the specialized treatment is effective in helping…
- Trial name
- NCT00763919
- Testing
- Psychoeducation module, Substance abuse module, Improved communication/rapport with provider module
- Where
- United States
- Volunteers
- 43 people
- Sponsor
- Case Western Reserve University
Kidney Transplantation, Treatment Refusal
Survey of Adherence to Immunosuppression and Other Medications in Kidney Transplant Patients
Goal: To define the causes and issues associated with nonadherence in our population Hypothesis: There is a difference in the rates and patterns of adherence to transplant medications versus other medications also taken by…
- Conditions
- Kidney Transplantation, Treatment Refusal, Patient Compliance
- Trial name
- NCT00433134
- Testing
- Adherence
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- State University of New York - Downstate Medical Center
Lung Cancer (NSCLC)
Percutaneous Pulsed Electric Field Ablation for Early-Stage NSCLC and Lung Oligometastases: A Safety and Efficacy Study
The goal of this observational study is to evaluate the performances of a percutaneous Pulsed Electrical Field (PEF) ablation to treat patients with primary early-stage lung cancer (NSCLC) or lung oligometastatic Tumors who are…
- Trial name
- NCT07799194
- Testing
- Pulsed Electric Field Ablation
- Where
- China
- Volunteers
- 10 people
- Sponsor
- Energenx Medical LTD.
Vaccine Refusal, Compliance, Patient
Vaccinations and People With Disabilities
The goal of this observational study is to learn about vaccinations hesitancy, delay or avoidance in children with chronic diseases, congenital anomalies or disabilities.
- Conditions
- Vaccine Refusal, Compliance, Patient, Disability, Intellectual, Congenital Disorders
- Trial name
- NCT05749419
- Where
- Israel
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Breast Cancer
Breast Cancer Trials Education Program
The purpose of this study is to test a program designed to increase African American and Hispanic American women's scientific literacy, knowledge of clinical trials, and to facilitate breast cancer clinical trial participation.
- Trial name
- NCT02808598
- Testing
- Breast Cancer Clinical Trials Education Program
- Where
- 2 sites in United States
- Volunteers
- 1,065 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Primary Focal Segmental Glomerulosclerosis
Obinutuzumab in Primary FSGS
The purpose of this study is to evaluate the safety and efficacy of Obinutuzumab in inducing complete or partial remission of proteinuria.
- Trial name
- NCT04983888
- Testing
- Obinutuzumab
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Mayo Clinic
Breast Cancer, Survivorship
Culturally Aware AET Non-Initiation Intervention
The purpose of this study is to examine the feasibility and acceptability of a brief, nurse-led intervention to support breast cancer survivors who have delayed initiation of hormonal therapy or who have concerns about starting…
- Conditions
- Breast Cancer, Survivorship, Treatment Compliance, Treatment Adherence
- Trial name
- NCT05465408
- Testing
- Culturally Aware Adjuvant Endocrine Therapy (AET) Non-Initiation Intervention
- Where
- 11 sites in United States
- Volunteers
- 35 people
- Sponsor
- Massachusetts General Hospital
Health Behavior, Colorectal Cancer
Building Engagement Using Financial Incentives Trial - Colorectal Cancer Screening
The goal of this pilot clinical trial is to determine feasibility and explore whether financial incentives paid to primary care patients for completing colorectal cancer screening increase completion of colorectal cancer…
- Conditions
- Health Behavior, Colorectal Cancer, Influenza, COVID-19
- Trial name
- BENEFIT-C (NCT06124131)
- Testing
- Financial incentive for colorectal cancer screening, Financial incentive for flu shot, Financial incentive for COVID-19 shot
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Tulane University
Participation Rate, Patient, Clinical Trials
Patients' Refusal to Participate in Surgical Research: Prevalence, Attributed Factors, and How to Overcome
This study aims to investigate the prevalence of refusal of participation in surgical clinical trials in our community. Furthermore, it aims to highlight potential factors contributing to refusal of participation.
- Trial name
- NCT07838285
- Testing
- Questionnaire
- Where
- Egypt
- Volunteers
- 372 people
- Sponsor
- Mansoura University
Vaccine Hesitancy, Health Education
Effect of Primary Care Education on Parents' Health-Related Perceptions and Attitudes
This study aims to evaluate the effect of a structured education program delivered in primary health care settings on parents of children aged 0-2 years.
- Conditions
- Vaccine Hesitancy, Health Education, Digital Health Literacy, Eco-anxiety
- Trial name
- NCT07381088
- Testing
- Structured Education Program
- Where
- Turkey (Türkiye)
- Volunteers
- 173 people, healthy volunteers welcome
- Sponsor
- Yuzuncu Yil University