Clinical trials: Patient Reported Outcome
Osteoarthritis (OA) of the Hip, Osteoarthritis (OA) of the Knee
Extended Post-operative Oral TXA in Primary THA
The goal of this clinical trial is to learn if extended post-operative oral tranexamic acid (TXA) - a medication that reduces bleeding by slowing the breakdown of blood clots - can improve functional recovery following surgery in…
- Trial name
- NCT07685743
- Testing
- Extended oral tranexamic acid regimen
- Volunteers
- 170 people
- Sponsor
- Oregon Health and Science University
COPD, Nurse-Patient Relations
Effectiveness of Motivational Interviewing in Patients With COPD
To determine the effect of motivational interviewing based on Pender's health promotion model on patient-reported outcomes in patients with COPD.
- Trial name
- NCT06783582
- Testing
- Motivational interviewing based on Pender's health promotion model
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Zeynep Yildirim
Radiodermatitis, Breast Neoplasms
Patient Reported Outcomes Using Mepitel Film During Radiotherapy
Breast cancer patients in post-operative radiotherapy (RT) often experience acute skin reactions like erythema, pain, itching and oversensitivity.
- Conditions
- Radiodermatitis, Breast Neoplasms, Side Effect
- Trial name
- NCT06133218
- Testing
- Mepitel Film
- Volunteers
- 101 people
- Sponsor
- Odense University Hospital
Multiple Sclerosis
Real-Life Outcomes of Multiple Sclerosis Treatment With Rebif
The purpose of this study is to determine whether Rebif has an impact on employment status, quality of life and cognition.
- Trial name
- RLO (NCT02377323)
- Testing
- MACFIMS, MSQoL-54
- Where
- Canada
- Volunteers
- 296 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Total Knee Arthroplasty for Gonarthrosis
Analysis of the Functional Impact of Total Knee Arthroplasty Using Quantified Gait Analysis and Proprioceptive Evaluation
Total knee arthroplasty remains the gold standard in the management of disabling gonarthrosis. Improved functional results, increased availability of care and an ageing population have all contributed to the rise in total knee…
- Trial name
- ARTHROPROMA (NCT06907368)
- Testing
- Quantitative Gait Analysis
- Where
- France
- Volunteers
- 15 people
- Sponsor
- University Hospital, Grenoble
Breast Neoplasm Malignant Female
Study Evaluating the Impact of Electronic Surveys on Patient-physician Communication and Quality of Life in Breast Cancer Patients
PRO-COM Project: Randomized-controlled study evaluating the impact of electronic patient reported outcome (ePRO) surveys on patient-physician communication and quality of life in patients with advanced breast cancer
- Trial name
- NCT03525990
- Testing
- Questionnaires
- Where
- 2 sites in Austria
- Volunteers
- 62 people
- Sponsor
- Dr. Vera Trommet
Rheumatoid Arthritis
JAKPOT (JAK Inhibitors and Predictors of Outcome in RheumaToid Arthritis)
Rheumatoid arthritis (RA) is a chronic, progressive autoimmune disease associated with inflammation and destruction of joints and systemic effects, which result in significant impact on patient's quality of life and function.
- Trial name
- JAKPOT (NCT04084223)
- Testing
- Ultrasound
- Where
- France
- Volunteers
- 51 people
- Sponsor
- University Hospital, Montpellier
Lung Cancer
Predicting Symptom Trajectories After Thoracoscopic Lung Cancer Surgery Using an Interpretable Machine Learning Model
Patients suffer from a variety of symptoms after thoracoscopic surgery. However, there is a lack of validated predictive tools to identify potentially high-risk patients.
- Trial name
- NCT06771947
- Where
- China
- Volunteers
- 1,500 people
- Sponsor
- Guangdong Provincial People's Hospital
Plaque Psoriasis
A Study to Assess the Effects of Switching From a Biologic Treatment to Tildrakizumab Using Patient-reported Outcomes in Adult Participants With Moderate to Severe Plaque Psoriasis
The main aim of this study is to assess the effects of switching from another biologic to tildrakizumab on patient-reported outcomes and to assess psoriasis intensity, patient's quality of life prior and after switching and the…
- Trial name
- NCT06030076
- Testing
- Tildrakizumab
- Where
- Austria
- Volunteers
- 50 people
- Sponsor
- Almirall, S.A.
Heart Failure, Anemia
RED-HF™ Trial - Reduction of Events With Darbepoetin Alfa in Heart Failure Trial
The purpose of the study is to determine the efficacy of treatment of anemia with darbepoetin alfa compared to placebo on the composite of time to death from any cause or first hospital admission for worsening heart failure in…
- Conditions
- Heart Failure, Anemia, Cardiovascular Disease, Ventricular Dysfunction
- Trial name
- NCT00358215
- Testing
- Darbepoetin alfa
- Where
- 754 sites in United States, Argentina and 34 more
- Volunteers
- 2,278 people
- Sponsor
- Amgen
Diabetes Mellitus
Insulin Glargine Plus Insulin Glulisine Multiple Daily Injections (MDI) Versus Premix Insulin Treatment in Subjects With Diabetes Mellitus (Type 1 or Type 2)
The purpose of this study is to test for superiority in improvements from baseline in patient reported outcomes in subjects with type 1 or type 2 diabetes when treated with insulin glargine plus rapid acting insulin glulisine MDI…
- Trial name
- NCT00135941
- Testing
- insulin glargine, insulin glulisine
- Where
- United States
- Volunteers
- 582 people
- Sponsor
- Sanofi
Hand Osteoarthritis
Outcomes After First-line Treatment of Hand Osteoarthritis
This study will investigate outcomes of a 3-month first-line treatment program for hand osteoarthritis, using data from the Swedish Osteoarthritis Registry.
- Trial name
- NCT07708454
- Testing
- 3 months of exercise and education
- Volunteers
- 2,000 people
- Sponsor
- Lund University
Head and Neck Cancers, Laryngeal Carcinoma
Telemedicine Follow-Up for Early Laryngeal Cancer: a Randomized Controlled Trial Comparing Care Close to Home Versus Standard of Care
The goal of this clinical trial is to evaluate whether Telemedicine follow-up is a satisfactory and safe alternative to traditional follow-up care for patients treated for early glottic (vocal cord) cancer, particularly those who…
- Trial name
- Telemedicine (NCT06940505)
- Testing
- Telemedicine Follow-up
- Where
- Netherlands
- Volunteers
- 140 people
- Sponsor
- University Medical Center Groningen
Endometrial Cancer
Carboplatin, Paclitaxel With or Without Avelumab in Advanced or Recurrent Endometrial Cancer
This study aims to evaluate the safety and activity of the Avelumab in combination with Carboplatin-Paclitaxel in advanced or recurrent endometrial cancer
- Trial name
- MITO END-3 (NCT03503786)
- Testing
- Carboplatin, Paclitaxel, Avelumab
- Where
- 11 sites in Italy
- Volunteers
- 125 people
- Sponsor
- National Cancer Institute, Naples
Multiple Sclerosis
Medication Usage and Patient Reported Outcomes Evaluation Via myBETAapp in Patients With Multiple Sclerosis Treated With Betaferon: a Pilot Study
The planned study will be a prospective, non-interventional, observational cohort study using the structure of a registry. Medication usage behavior will be observed for 6 months, while documentation behavior on the wellness…
- Trial name
- PROmyBETAapp (NCT03134573)
- Testing
- Interferon beta-1b (Betaferon, BAY86-5046), Betaconnect auto-injector, myBETAapp
- Where
- Germany
- Volunteers
- 96 people
- Sponsor
- Bayer
Stroke, Sleep Wake Disorders
The SLEEPR Study: SLEep Effects on Post-stroke Rehabilitation
Sleep is critical for health and quality of life; however, little is known about the prevalence or impact of non obstructive sleep apnea (non-OSA) sleep disorders in people with stroke.
- Conditions
- Stroke, Sleep Wake Disorders, Rehabilitation, Recovery of Function
- Trial name
- SLEEPR (NCT05012605)
- Testing
- Observation
- Where
- 6 sites in United States
- Volunteers
- 200 people
- Sponsor
- State University of New York - Upstate Medical University
IBD-Inflammatory Bowel Disease, UC - Ulcerative Colitis
Impact of Therapeutic Intervention on Quality of Life in Patients With Ulcerative Colitis
This study is therefore postulated as a clear alternative that evaluates patients´quality of life, and recognises fecal calprotectin as an inflammatory marker.
- Trial name
- CAVI_CU (NCT05271773)
- Where
- 10 sites in Spain
- Volunteers
- 234 people
- Sponsor
- Grupo Espanol de Trabajo en Enfermedad de Crohn y Colitis Ulcerosa
Breast Cancer Stage I, Breast Cancer Stage II
Patient Reported Outcomes After Oncoplastic Breast Conserving Surgery
The goal of this study is to assess patient satisfaction after oncoplastic breast conserving surgery. With the help of a breast-questionnaire the patient satisfaction will be assessed before the surgery and 4 weeks, 6 months and…
- Conditions
- Breast Cancer Stage I, Breast Cancer Stage II, Breast Cancer in Situ
- Trial name
- NCT05724758
- Testing
- Breast-conserving surgery
- Volunteers
- 100 people
- Sponsor
- Brust-Zentrum AG
Cancer
Implementing REmote SymPtom mOnitoring and maNagement (RESPONd)
The goal of this study is to understand if the implementation of a remote symptom monitoring and management program improves outcomes.
- Trial name
- RESPONd (NCT07024329)
- Testing
- Remote Symptom Monitoring and Management, Clinic Team Huddle
- Where
- 4 sites in Canada
- Volunteers
- 1,055 people
- Sponsor
- University of Calgary
Transgenderism, Erectile Dysfunction
Epithesis Versus Prosthesis in Post-phalloplasty Transgender Patients.
Transgender and gender diverse (TGD) individuals most often choose for phalloplasty as a means to create masculine external genitalia.
- Conditions
- Transgenderism, Erectile Dysfunction, Prosthesis Durability, Gender Dysphoria
- Trial name
- EROS (NCT05883553)
- Testing
- Usability and added value of device within sexual activity
- Where
- 2 sites in Belgium, Netherlands
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University Hospital, Ghent
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