Clinical trials: Patient With Schizophrenia Spectrum Disorder
Schizophrenia
Study on Metabolic Parameters of Sertindole in Patients With Schizophrenia
The purpose of this exploratory study is to evaluate the effects of sertindole and olanzapine on metabolic parameters and syndrome in patients with schizophrenia.
- Trial name
- NCT00759460
- Testing
- Sertindole, Olanzapine
- Where
- China
- Volunteers
- 250 people
- Sponsor
- H. Lundbeck A/S
Schizophrenia and Related Disorders, Psychotic Disorders
Exercise and Overnight Motor Sequence Task
The objective of this randomized controlled trial (RCT) is to compare the changes of the sleep-related memory functions in patients with psychosis after they have completed the 12-week high-intensity exercise intervention, the…
- Trial name
- EOMST (NCT03800368)
- Testing
- Exercise, Non-exercise
- Volunteers
- 51 people
- Sponsor
- The University of Hong Kong
Schizophrenia, Schizophrenia and Disorders With Psychotic Features
Evaluation of the Necessity of Long-term Pharmacological Treatment With Antipsychotics in Schizophrenic Patients
The main objective of the trial is to evaluate, how long an antipsychotic relapse-prevention should be continued and to which time a patient with schizophrenia is protected enough, so that a withdrawal or reduction of the…
- Conditions
- Schizophrenia, Schizophrenia and Disorders With Psychotic Features, Schizoaffective Disorders
- Trial name
- NCT02307396
- Testing
- Olanzapine, Amisulpride, Risperidone
- Where
- Germany
- Volunteers
- 21 people
- Sponsor
- Technical University of Munich
Schizophrenia
High-Dose Oral Ziprasidone Versus Conventional Dosing in Participants With Residual Schizophrenia Symptoms
The primary aims of this study are to assess tolerability of ziprasidone dose escalation to 320 milligrams per day (mg/d) compared to continued standard treatment (placebo) as measured by the Side Effect Checklist, Simpson Angus…
- Trial name
- HDZ (NCT00403546)
- Testing
- Ziprasidone 80-160 mg/d, Ziprasidone 160 mg/d
- Where
- 9 sites in United States
- Volunteers
- 131 people
- Sponsor
- Donald C. Goff, MD
Schizophrenia, Schizoaffective Disorder
Magnesium Variations and Cardiometabolic Risk in Patients With Antipsychotic Drugs
Background: Antipsychotics can induce metabolic disorders such as obesity, hyperglycemia, dyslipidemia or metabolic syndrome. It has been observed that treatment with antipsychotic could be accompanied by a decrease in the…
- Conditions
- Schizophrenia, Schizoaffective Disorder, Bipolar Disorder
- Trial name
- NCT02986490
- Testing
- Blood sample
- Where
- France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Montpellier
Schizophrenia, Schizoaffective Disorder
L-arginine add-on Therapy in Patients With Schizophrenia
This study evaluates the addition of L-Arginine to the usual regimen in the treatment of schizophrenia in adults. As a requisite of crossover design, half of the participants started with L-Arginine and the other half with…
- Trial name
- NCT02398279
- Testing
- L-Arginine
- Where
- Turkey (Türkiye)
- Volunteers
- 12 people
- Sponsor
- Hacettepe University
Psychotic Disorders, Psychological Trauma
Prevalence of Traumatic Events and PTSD in Immigrant and Non-immigrant Patients With Psychotic Disorder
Higher rates of psychosis are described in migrant population. Likewise, this populations could suffer several adversities during migration process that could lead to higher exposure to traumatic events and higher rates of…
- Conditions
- Psychotic Disorders, Psychological Trauma, Stress, Psychological, Cross-Cultural Comparison
- Trial name
- NCT04867447
- Testing
- Psychological trauma evaluation
- Where
- Spain
- Volunteers
- 199 people
- Sponsor
- Parc de Salut Mar
Schizophrenia
Effects of Cariprazine on Cardiac Repolarization in Patients With Schizophrenia
This study will evaluate the effects of sequential multiple dose regimens of cariprazine on cardiac repolarization in patients with schizophrenia.
- Trial name
- NCT01376076
- Testing
- Cariprazine, Risperidone/Moxifloxacin
- Where
- 4 sites in United States
- Volunteers
- 129 people
- Sponsor
- Forest Laboratories
Schizophrenia and Related Disorders
An Extension Protocol for Patients Who Previously Completed the TMS Pilot Study
This is an open-label extension study to continue to evaluate the safety, tolerability and efficacy of the Repetitive Transcranial Magnetic Stimulation (rTMS) in subjects with schizophrenia or schizoaffective disorder who…
- Trial name
- NCT05526833
- Testing
- Repetitive Transcranial Magnetic Stimulation (rTMS)
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Columbia University
Schizophrenia
Safety Study With Paliperidone ER Extended-Release (ER) Tablets in Geriatric Patients With Schizophrenia
The primary objective of the study is to evaluate the safety and tolerability of flexible dosages of paliperidone ER as compared with placebo in patients with schizophrenia who are 65 years of age or older.
- Trial name
- NCT00085748
- Testing
- paliperidone ER
- Volunteers
- 114 people
- Sponsor
- Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Waist Circumference Measurements, Schizophrenia
Waist Circumference Measurements in Schizophrenic Patients
The prevalence of metabolic syndrome(MS) among pt's with schizophrenia has been reported to be high, ranging from 24 to 43% in males and 27 to 52% in females.
- Conditions
- Waist Circumference Measurements, Schizophrenia, Cardiovascular Risk Factor
- Trial name
- NCT01243034
- Where
- Taiwan
- Volunteers
- 80 people
- Sponsor
- Changhua Christian Hospital
Schizophrenia; Psychosis
The IM-ZBULLE Study : " Z-track " and " Airlock " Techniques During Intramuscular Injection of Haloperidol Decanoate
Intramuscular injection (IMI) is the process of administering a drug treatment into muscle tissue. The transmission of skills in this care practice is essentially based on the experience of peers.
- Trial name
- IM-ZBULLE (NCT05995457)
- Testing
- Intramuscular injection of Haloperidol decanoate using the "Z-track" and "Airlock" techniques, Intramuscular injection of Haloperidol decanoate using standard techniques
- Where
- France
- Volunteers
- 84 people
- Sponsor
- Centre Hospitalier St Anne
Schizophrenia, Schizoaffective
Does tDCS Change Synaptic Density in the Brains of Patients With Schizophrenia
This study will examine changes in synaptic density with transcranial direct current stimulation (tDCS) in the brains of patients with schizophrenia.
- Trial name
- NCT05435300
- Testing
- PET Scan
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- Centre for Addiction and Mental Health
Schizophrenia
Evaluation of Stroop Effect in Patients With Schizophrenia
The main objective of this study is to assess whether attention deficits and executive functions in patients with schizophrenia are general (semantic and response conflict) or specific (semantic or response conflict).
- Trial name
- STROOP (NCT03163706)
- Testing
- Modified Stroop effect
- Where
- France
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University Hospital, Clermont-Ferrand
Psychotic Disorders
Longitudinal Multimodal Neuroimaging Studies in Patients With First Episode Psychosis
The purpose of this study is to investigate the structural, functional and chemical brain abnormalities in patients with first episode psychosis and assess the evolution of these abnormalities during the course of the disease.
- Trial name
- NCT01688765
- Testing
- Observational
- Where
- United States
- Volunteers
- 187 people, healthy volunteers welcome
- Sponsor
- Mclean Hospital
Schizophrenia
The Danish Region Midt Schizophrenia Cohort
The objective of this study is to recruit patients at the first diagnosis with a schizophrenia spectrum disorder (SSD) and ultra-high risk patients (UHR), defined as patients with drug abuse and psychotic symptoms indicating a…
- Trial name
- RMS (NCT06431009)
- Testing
- Treatment-as-usual
- Where
- 5 sites in Denmark
- Volunteers
- 350 people
- Sponsor
- University of Aarhus
Healthy, Schizophrenia
Electrophysiology and Blood Flow in Patients With Schizophrenia and Their Siblings
This study will explore how the brain works during memory testing in an effort to understand why some patients with schizophrenia have memory difficulties.
- Trial name
- NCT00001921
- Where
- United States
- Volunteers
- 1,386 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
Schizophrenia; Psychosis, Cognitive Impairment
Efficacy of Computer-assisted Cognitive Remediation in Patients With Schizophrenia
Objective: To determine the efficacy of computer-assisted cognitive remediation (CACR) in patients with chronic schizophrenia in the community settings.
- Conditions
- Schizophrenia; Psychosis, Cognitive Impairment, Executive Function, Randomized Controlled Trial
- Trial name
- NCT04773171
- Testing
- Computer-assisted Cognitive Remediation, Conventional training programmes
- Where
- Hong Kong
- Volunteers
- 72 people
- Sponsor
- The Hong Kong Polytechnic University
Schizophrenia
Repetitive Transcranial Magnetic Stimulation and Intermittent Theta Burst (iTBS) in Schizophrenia
The pilot studies have showed that theta burst stimulation (TBS) can have the more rapid and durable effects to the apply traditional rTMS protocols.
- Trial name
- NCT01315587
- Testing
- repetitive Transcranial Magnetic Stimulation (Magstim rapid2 ), repetitive Transcranial Magnetic Stimulation (Magstim rapid2), repetitive Transcranial Magnetic Stimulation(Magstim rapid2)
- Where
- Iran
- Volunteers
- 30 people
- Sponsor
- University of Tehran
Alzheimer's Disease, Dementia
A Study of the Effectiveness and Safety of Risperidone Versus Placebo in the Treatment of Patients With Hallucinations and Delusions Associated With Alzheimer's Disease
The purpose of this study is to assess the effectiveness and safety of risperidone (an antipsychotic medication) versus placebo for the treatment of patients with hallucinations and delusions associated with Alzheimer's disease.
- Trial name
- NCT00287742
- Testing
- risperidone
- Volunteers
- 33 people
- Sponsor
- Janssen Pharmaceutical K.K.
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.