Clinical trials: Patient With Schizophrenia Spectrum Disorder
Psychotic Disorders
Comparison of a Speech-Language Assessment Tool for Pragmatic and Discourse Skills in Schizophrenia Spectrum Disorders
The scientific literature has largely objectified language disorders in schizophrenia. And more precisely, the impairment of pragmatic and discursive language skills.
- Trial name
- VEOS (NCT05742893)
- Testing
- Measurement of pragmatic and discourse test scores in the two scales.
- Where
- France
- Volunteers
- 30 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Schizophrenia
tDCS to Enhance Cognitive Training in Schizophrenia
The primary aim for the study is to determine whether transcranial direct current stimulation (tDCS) enhances training gains on cognitive training (CT) tasks.
- Trial name
- NCT01733602
- Testing
- transcranial direct current stimulation
- Where
- Australia
- Volunteers
- 52 people
- Sponsor
- The University of New South Wales
Schizophrenia
Evaluate the Efficacy of a Global Dental Health Promotion Program on Dental Hygiene in Patients With Schizophrenia.
There are few disease prevention programs or programs to manage somatic disorders in a psychiatric context. The aim of this study is to evaluate the impact in the medium term of a global program to promote dental health on…
- Trial name
- EBENE (NCT02512367)
- Testing
- Dental care education program, Surveillance
- Where
- 12 sites in France
- Volunteers
- 79 people
- Sponsor
- Centre Hospitalier Universitaire Dijon
Schizophrenia, Treatment-Resistant
An Open-Label, Single-Arm Clinical Trial Evaluating the Safety and Efficacy of Amisulpride in Treating Patients With Schizophrenia and Schizoaffective Disorder Who Have Treatment-Resistant Positive Symptoms
The objectives of this study are to evaluate the safety and efficacy of Amisulpride as an add-on therapy or alternative monotherapy in treating patients with schizophrenia or schizoaffective disorder who have treatment-resistant…
- Trial name
- AmisulprideTRS (NCT05956600)
- Testing
- Amisulpride 50 MG
- Sponsor
- University of California, Los Angeles
Schizophrenia, Catatonic, Schizophrenia, Disorganized
Evaluation of Efficacy and Safety of Long-acting Risperidone Microspheres in Patients With Schizophrenia or Other Psychotic Disorders When Switching From Typical Antipsychotic (Oral/Depot) or Atypical Oral Other Than Risperidone
The purpose of this study is to evaluate the efficacy, tolerability and safety of patients on long-acting Risperidone microshpheres injection.
- Conditions
- Schizophrenia, Catatonic, Schizophrenia, Disorganized, Schizophrenia, Paranoid, Schizophrenia
- Trial name
- NCT00563017
- Testing
- Long-acting Risperidone microspheres injection
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Hospital Authority, Hong Kong
Schizophrenia, Schizophreniform Disorder
Association of Amisulpride Response in Schizophrenia With Brain Image
1. Study rationale - Nielsen et al reported that after 6 weeks of amisulpride treatment, patients with schizophrenia showed an increase in the anticipation-related functional MRI signal.
- Trial name
- ARB (NCT02095938)
- Testing
- amisulpride
- Volunteers
- 20 people
- Sponsor
- CHA University
Schizophrenia, Bipolar I Disorder
Safety and Tolerability of Open-Labeled Iloperidone in Adolescents
To evaluate the safety and tolerability of iloperidone in adolescent patients with schizophrenia or bipolar I disorder for up to 52 weeks of treatment.
- Trial name
- NCT05648591
- Testing
- Iloperidone
- Where
- 11 sites in United States
- Volunteers
- 100 people
- Sponsor
- Vanda Pharmaceuticals
Schizophrenia
Predictors of Persistence in Patients With Schizophrenia Treated With Once-monthly Aripiprazole in Spain
This is an observational, retrospective, non-interventional study that will include schizophrenic patients who were initiated on AOM treatment during an schizophrenia-related hospitalisation at least 6 months before data…
- Trial name
- PROSIGO (NCT03130478)
- Where
- 15 sites in Spain
- Volunteers
- 119 people
- Sponsor
- Otsuka Pharmaceutical Europe Ltd
Schizophrenia
A Long-term Administration Trial of Brexpiprazole Once-weekly (QW) Formulation in Patients With Schizophrenia
Confirm the tolerability and safety of long-term administration of the brexpiprazole QW formulation in patients with schizophrenia
- Trial name
- NCT05326347
- Testing
- OPC-34712FUM/ Brexpiprazole fumarate
- Where
- Japan
- Volunteers
- 247 people
- Sponsor
- Otsuka Pharmaceutical Co., Ltd.
Schizophrenia
Comparison of Intramuscular Olanzapine and Intramuscular Haloperidol in Patients With Schizophrenia
The purpose of this study is to compare intramuscular Olanzapine and intramuscular Haloperidol in changing of agitation in patients with schizophrenia
- Trial name
- NCT00485901
- Testing
- Olanzapine Hydrochloride, Haloperidol
- Where
- Taiwan
- Volunteers
- 50 people
- Sponsor
- Eli Lilly and Company
Schizophrenia
The Efficacy And Safety Of Intramuscular Ziprasidone For Three Days In Patients With Psychotic Agitation
1. The title of this study is a multi-center,non randomized,open-labeled,intervention study:the efficacy and safety of intramuscular ziprasidone for three days in patients with acute psychotic agitation. 2.
- Trial name
- NCT02935998
- Testing
- Ziprasidone
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- Yang Fude
Schizophrenia, Schizoaffective Disorder
Simvastatin Addition for Patients With Recent-onset Schizophrenia
Rationale: There is ample evidence that inflammatory processes play a role in the pathophysiology of schizophrenia. Although Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) have been shown to be able to reduce symptoms in these…
- Conditions
- Schizophrenia, Schizoaffective Disorder, Schizophreniform Disorder, Psychosis NOS
- Trial name
- NCT01999309
- Testing
- Simvastatin
- Where
- 2 sites in Netherlands
- Volunteers
- 121 people
- Sponsor
- Iris Sommer
Schizophrenia
Evaluation of Physical Activity, Physical Fitness, and Quality of Life in Patients With Schizophrenia
The aim of this study is to evaluate schizophrenic patients who benefit from community mental health center services in terms of physical activity, physical fitness, and quality of life.
- Trial name
- NCT05449977
- Testing
- Diagnose
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Yeditepe University
Schizophrenia, Antipyretics Toxicity
Prolactin Change in Chinese Patients With Schizophrenia After Antipsychotics Treatment
Objective: Hyperprolactinemia(HPRL) which can result in a series of prolactin-related symptoms is a frequent adverse effect of antipsychotics.
- Conditions
- Schizophrenia, Antipyretics Toxicity, Prolactin Excess
- Trial name
- NCT04002258
- Testing
- Antipsychotic
- Where
- China
- Volunteers
- 10,363 people
- Sponsor
- Shanghai Mental Health Center
Schizophrenia, Bipolar Disorder
A Study of the Effect of Carbamazepine on the Pharmacokinetics of Paliperidone Extended Release (ER) in Patients With Schizophrenia or Bipolar I Disorder
The purposes of this study are to evaluate the effects of a potent metabolic enzyme inducer, carbamazepine, on the steady-state pharmacokinetics of orally administered paliperidone ER and to evaluate the safety and tolerability…
- Trial name
- NCT00892125
- Testing
- paliperidone ER; Carbamazepine
- Volunteers
- 64 people
- Sponsor
- Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Psychotic Disorders
Serial Comparisons of Abdominal and Neurological MRI Scans
The purpose of this study is to compare abdominal weight gain and fat distribution to changes in brain morphology in people taking antipsychotic medications.
- Trial name
- SCANMRI (NCT02009969)
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- University of British Columbia
Schizophrenia, Schizoaffective Disorder
Effects of Modafinil on Brain Function in Patients With Schizophrenia
This study will evaluate whether modafinil improves cognition in patients with schizophrenia and healthy volunteers. Modafinil is a drug that has been FDA approved for day-time sleepiness and allegedly increase the amount of the…
- Trial name
- NCT00057707
- Testing
- Modafinil, Functional MRI, Neuropsychological Testing
- Where
- United States
- Volunteers
- 176 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
Schizophrenia
A Study in Italy About Evidence Based Psychosocial/Rehabilitative Interventions in Patients With Early Schizophrenia Treated Continuously With Antipsychotics
This is a prospective, observational, naturalistic study conducted according to Italian law. The Investigators are interested in observing how often Evidence Based (EB) psychosocial and rehabilitative interventions are actually…
- Trial name
- ESCHILO (NCT03693794)
- Where
- Italy
- Volunteers
- 270 people
- Sponsor
- Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia
Social Cognition in Patients With Schizophrenia
Treating Social Cognition With Theta Burst Stimulation: a Multicentric Study
The purpose of the study is to test a new treatment of social cognition deficits in patients with schizophrenia or schizoaffective disorder by transcranial magnetic stimulation (theta-burst).
- Trial name
- TBS-COG (NCT02479919)
- Testing
- Magstim® Active TBS
- Where
- 3 sites in France
- Volunteers
- 61 people
- Sponsor
- University Hospital, Caen
Schizophrenia
Add-on Sodium Nitroprusside to Treatment as Usual in Schizophrenia
In spite of the numerous studies on schizophrenia, its etiology and physiopathology remain unknown. Evidence suggests a possible implication of nitric oxide (NO) in schizophrenia.
- Trial name
- NCT01548612
- Testing
- Sodium nitroprusside, Glucose solution
- Where
- Brazil
- Volunteers
- 20 people
- Sponsor
- University of Sao Paulo
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