Clinical trials: Patient With Schizophrenia Spectrum Disorder
Schizophrenia, Constipation
Kombucha Tea for Improving Defecation in Patients With Schizophrenia- a Randomized Controlled Study
Patients with schizophrenia frequently have difficulties in bowel habits due to medical adverse effects and unhealthy lifestyle, and the use of various interventions to ameliorate the problems have been noted in clinical setting.
- Conditions
- Schizophrenia, Constipation, Kombucha Tea
- Trial name
- NCT06502509
- Testing
- Commercial Kombucha tea (Brand name E-Ben Organic Kombucha Lemon), Lemon tea
- Where
- Taiwan
- Volunteers
- 80 people
- Sponsor
- TsaoTun Psychiatric Center, Department of Health, Taiwan
Cognitive Impairments, Schizophrenia
Effects of Transcranial Direct Current Stimulation on Cognitive Rehabilitation in Schizophrenia
The aim of this prospective, randomized, double-blind, placebo-controlled study is to assess whether transcranial direct current stimulation (tDCS) applied prior to RehaCom cognitive training can improve cognitive functioning in…
- Trial name
- NCT07273175
- Testing
- active tDCS
- Where
- Poland
- Volunteers
- 120 people
- Sponsor
- Medical University of Lodz
Schizophrenia, Mental Disorders
Study of the Activation of Proinflammatory Pathways of Toll-like Receptors in Schizophrenia Patients
The study of immune pathways involved in the etiopathogeny of schizophrenia would be an important advance to understand the mechanisms involved in the development of this disease and it would be a turning point in drug therapy.
- Conditions
- Schizophrenia, Mental Disorders, Psychotic Disorders
- Trial name
- PAFIP_TLR (NCT02897167)
- Testing
- Retrospective study of frozen samples, Prospective study of fresh samples
- Where
- Spain
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Fundación Marques de Valdecilla
Schizophrenia
Switching From Consta® to Sustenna® in Patients With Schizophrenia
The aim of this study is observation of effectiveness and side effect of patients with schizophrenia who will switch the antipsychotics from risperidone long acting injection to paliperidone palmitate.
- Trial name
- NCT01698216
- Where
- South Korea
- Volunteers
- 50 people
- Sponsor
- Seoul National University Hospital
Schizophrenia
Validation of a Scale to Evaluate the Perception of Oral Health in Patients With Schizophrenia
Apart from objective criteria for the evaluation of oral health (CAO, CPI…), there are no scales to evaluate the oral health of patients with schizophrenia.
- Trial name
- QUALITY (NCT02730832)
- Testing
- Questionnaires completed at D0, Questionnaires completed at D15 (test-retest for 30 patients)
- Where
- France
- Volunteers
- 59 people
- Sponsor
- Centre Hospitalier Universitaire Dijon
Schizophrenia
A Study to Assess the Rate of Hospitalization in Participants With Schizophrenia Treated With Antipsychotics
The primary purpose of the study is to compare the rate of hospitalization associated with psychotic relapse in participants with schizophrenia treated one year before with oral antipsychotics and one year after with long acting…
- Trial name
- REALAI (NCT02712463)
- Where
- 11 sites in Brazil, Mexico
- Volunteers
- 310 people
- Sponsor
- Janssen-Cilag Ltd.
Schizophrenia
An Open Trial of Allopurinol in Patients With Poorly Responsive Schizophrenia
This is a four week open label trial of ALLOPURINOL to the treatment regime of ten (10) poorly responsive patients with schizophrenia, monitoring their response and side-effects. No change in medication is required.
- Trial name
- NCT00823199
- Testing
- Allopurinal
- Volunteers
- 10 people
- Sponsor
- Bronx Psychiatric Center
Schizophrenia
The Management of Schizophrenia in Clinical Practice (MOSAIC)
This study is a disease-based registry designed to follow patients with a DSM-IV-TR (Diagnostic and Statistic Manual of Mental Disorders, Text Revision) diagnosis of schizophrenia, schizoaffective disorder, or schizophreniform…
- Trial name
- NCT01746134
- Where
- 44 sites in United States
- Volunteers
- 557 people
- Sponsor
- Genentech, Inc.
Schizophrenia, Virtual Reality
Level of Immersion of Virtual Reality and Cognition and Motor Performance in Patients of Schizophrenia Spectrum Disorder
Schizophrenia Spectrum Disorder (SSD) is the main diagnosis in subjects with mental disability. The number of disabled SSD increased yearly and might be due to the ineffective medical and rehabilitative interventions on improving…
- Conditions
- Schizophrenia, Virtual Reality, Video Games, Multi-tasks
- Trial name
- NCT04629898
- Testing
- multi-task in the real world and virtual reality video sport games
- Where
- Taiwan
- Volunteers
- 25 people
- Sponsor
- National Taiwan Normal University
Schizophrenia
Paliperidone Palmitate Flexible Dosing in Schizophrenia
This study explores the tolerability, safety and efficacy (i.e. how well the drug works) of flexibly dosed paliperidone palmitate in the treatment of schizophrenia in patients previously unsuccessfully treated with other oral or…
- Trial name
- PALMFlexS (NCT01281527)
- Testing
- Paliperidone Palmitate
- Where
- 127 sites in Austria, Belgium and 18 more
- Volunteers
- 1,044 people
- Sponsor
- Janssen-Cilag International NV
Adolescent Schizophrenia, Child or Adolescent Bipolar I Disorder, Manic or Mixed Episode With or Without Psychotic Features
Safety and Tolerability of Aripiprazole in Adolescents With Schizophrenia or Children and Adolescents With Bipolar I Disorder, Manic or Mixed Episode With or Without Psychotic Features.
This is an open-label study consisting of a screening period, a conversion/titration phase (Phase 1), an open-label treatment phase (Phase 2), and a follow-up period.
- Trial name
- ATTAIN 267 (NCT01122927)
- Testing
- Aripiprazole
- Where
- 101 sites in United States, Bulgaria and 11 more
- Volunteers
- 524 people
- Sponsor
- Otsuka Pharmaceutical Development & Commercialization, Inc.
Schizophrenia
Metabolic Signatures and Biomarkers in Schizophrenia
We plan to use a metabolomics lipid platform to map biochemical signatures in unmedicated schizophrenic patients prior to and 4 weeks post treatment with the antipsychotic drug aripiprazole and compare that to lipid perturbations…
- Trial name
- NCT00466310
- Testing
- Aripiprazole, Risperidone, Healthy volunteers
- Where
- United States
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- Duke University
Schizophrenia, Blooddraw
Family-based Genetic Long-term Study of Brain Function in Schizophrenia
The goal of this research is to find out possible susceptible gene(s) in schizophrenic patients with family history and 5-year period functional changes of brain among the members of family, in order to further analysis factors…
- Conditions
- Schizophrenia, Blooddraw, MRI
- Trial name
- FamilySchizo (NCT01045824)
- Where
- Taiwan
- Volunteers
- 600 people
- Sponsor
- Taichung Veterans General Hospital
Bipolar Disorder, Major Depressive Disorder
Sleep Quality, Cognitive Performance, and Computerized Cognitive Training
Poor sleep quality is common in neuropsychiatric conditions and some of the problems associated with poor sleep at night may be due to medication side effects or reduced efficacy of certain treatments.
- Conditions
- Bipolar Disorder, Major Depressive Disorder, Psychosis
- Trial name
- NCT06328140
- Testing
- Lurasidone, FDA Approved antidepressant treatment
- Where
- United States
- Sponsor
- George West Mental Health Foundation d/b/a Skyland Trail
Schizophrenia, Schizoaffective Disorder
Improving Adherence to Oral Antipsychotic Medications in People With Schizophrenia
This study will determine the comparative effectiveness of two systems designed to improve medication adherence in people with schizophrenia.
- Trial name
- NCT00406718
- Testing
- Med-eMonitor, PharmCAT, Treatment as Usual
- Where
- United States
- Volunteers
- 197 people
- Sponsor
- The University of Texas Health Science Center at San Antonio
Schizophrenia, Auditory Hallucination
Real-time fMRI Neurofeedback in Patients With Schizophrenia and Auditory Hallucinations
Neurofeedback intervention aimed to regulate the superior temporal gyrus (STG) activation and default mode network (DMN) connectivity as well as to reduce the auditory hallucinations (AH) schizophrenia patients with medication…
- Conditions
- Schizophrenia, Auditory Hallucination, Treatment-resistant Schizophrenia
- Trial name
- NCT05299749
- Testing
- stg-rt-fMRI-Neurofeeback
- Where
- United States
- Volunteers
- 104 people
- Sponsor
- Boston VA Research Institute, Inc.
Psychosis, Dementia
A Study of MP-101 in Dementia-Related Psychosis and/or Agitation and Aggression
A ten-week study to assess MP-101 in Dementia-Related Psychosis and/or Agitation and Aggression
- Conditions
- Psychosis, Dementia, Aggression, Agitation
- Trial name
- NCT03044249
- Testing
- MP-101
- Where
- 20 sites in United States, Canada
- Volunteers
- 81 people
- Sponsor
- Mediti Pharma Inc.
Schizophrenia, Bipolar Disorder
Time,Self and Spontaneous Mental Activities in Patients With Psychotic Disorders
The main purpose of the study is to examine to which extent abnormalities in the dynamics of neural activities observed in patients with psychosis is related to difficulties at ordering simple visual stimuli and/or personal…
- Trial name
- Self and Time (NCT02765880)
- Testing
- fMRI, EEG
- Where
- France
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- University Hospital, Strasbourg, France
Schizophrenia Disorder
Assessment of Physical Activity, Balance, Muscle Strength, and Cognitive Function in Patients Diagnosed With Schizophrenia
Schizophrenia is a serious mental health condition that affects individuals' thinking, perception, emotional responses, and behavior.
- Trial name
- NCT07141966
- Where
- Turkey (Türkiye)
- Volunteers
- 35 people
- Sponsor
- Dr. Lutfi Kirdar Kartal Training and Research Hospital
Schizophrenia, Schizoaffective Disorder
Estimating and Reducing the Cardiovascular Risk of Patients With Schizophrenia Drugs From Lipid Measures and Ischemic Electrocardiographic Changes
The primary goal of this study is to examine the triglyceride/high-density lipoprotein (TG/HDL) ratio and the ischemic EKG changes in patients with schizophrenia, schizoaffective disorder or bipolar disorder.
- Conditions
- Schizophrenia, Schizoaffective Disorder, Bipolar Disorder
- Trial name
- NCT00288353
- Testing
- aripiprazole (Abilify), ziprasidone (Geodon)
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- Northwestern University
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