Clinical trials: Patient-Reported Outcomes
Early Breast Cancer, Skin Condition
An Observational Real-world Study to Evaluate the Impact of Dermatological Toxicities on the Quality of Life in Patients With Early Breast Cancer Treated With Adjuvant Endocrine Therapy - BCARE (Breast Cancer Adjuvant Real-world Evaluation of Dermatological Adverse Events)
The goal of this European observational study (Frane, Spain, italy, Spain and Greece) is to describe the quality of life related to dermatological toxicities, in adult women patients with Early Breast Cancer (EBC), treated with…
- Conditions
- Early Breast Cancer, Skin Condition, Quality of Life
- Trial name
- BCARE (NCT06690489)
- Where
- 9 sites in France, Greece and 2 more
- Volunteers
- 155 people
- Sponsor
- Pierre Fabre Medicament
IBS
Cl-Pharm-IBS-ML-2026
The purpose of this study is to identify distinct subgroups (phenotypes) of Irritable Bowel Syndrome (IBS) patients. While traditional IBS classification relies mainly on bowel habits, this research uses a multidimensional…
- Trial name
- NCT07809646
- Testing
- Questionnaire and Physical Exam
- Volunteers
- 500 people
- Sponsor
- Tanta University
Ulcerative Colitis
Generate Real World Data On Tofacitinib Induction Therapy and Changes In Clinical and Patient Reported Outcomes.
This study is expected to contribute to the body of real-world data of tofacitinib's safety and efficacy profile in ulcerative colitis.
- Trial name
- KIC-START (NCT05069259)
- Testing
- Stool sample collection
- Where
- 5 sites in Switzerland
- Volunteers
- 18 people
- Sponsor
- Pfizer
Transthyretin Amyloidosis
Patient-Reported Outcome Measures in Wild-Type and Variant Cardiac Transthyretin Amyloidosis
Specific, standardized, comprehensive, universally accepted Patient-Reported Outcome Measures (PROMs) are currently lacking for variant and wild-type cardiac amyloid transthyretin amyloidosis (v-ATTR/wt-ATTR).
- Trial name
- ITALY (NCT04563286)
- Testing
- questionnaire on life quality
- Where
- 5 sites in Italy
- Volunteers
- 250 people
- Sponsor
- University of Messina
Cataract, IOL
Visual Outcomes With a Trifocal IOL in Subjects With Open-angle Glaucoma
This study will examine the visual outcomes of subjects undergoing cataract surgery and minimally invasive glaucoma surgery with the implantation of a trifocal intraocular lens.
- Conditions
- Cataract, IOL, Glaucoma, Open-Angle
- Trial name
- NCT04619654
- Testing
- Cataract surgery with implantation of trifocal IOL combined with trabecular scaffold
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Vold Vision P.L.L.C
Digestive Cancer
Impact of Patient Reported Outcomes for Pre-chemotherapy Medical Decision in Day Patients With Digestive Cancer
The investigators hypothesize that an early assessment of the clinical toxicity of the patient is possible via patient reported outcomes and that this information provides at least the same information level as the clinical…
- Trial name
- PRO Link (NCT04008056)
- Testing
- Patient Reported Outcome questionnaire
- Where
- France
- Volunteers
- 138 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Patients Scheduled to Undergo Surgery on the Gynecology Service
Electronic Reporting of Symptoms After Surgery
The purpose of this pilot study is to find out if patients are willing to self-report symptoms in the first 5 days following discharge, or when they leave the hospital after "ambulatory surgery" ("ambulatory surgery" is when the…
- Trial name
- NCT02700256
- Testing
- survey
- Where
- 5 sites in United States
- Volunteers
- 135 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Fusion of Spine, Lumbar Region, Anesthesia, Local
Effects of Erector Spinae Plane Block on Postoperative Pain Following Lumbar Fusion Surgery
The purpose of this study is to determine if the method for injecting local anesthesia affects patients' pain and opioid usage after surgery.
- Conditions
- Fusion of Spine, Lumbar Region, Anesthesia, Local, Pain, Postoperative, Opioid Use
- Trial name
- NCT06528288
- Testing
- Erector Spinae Plane Block, Subcutaneous Anesthesia
- Where
- United States
- Volunteers
- 66 people
- Sponsor
- University of Massachusetts, Worcester
Heart Defects, Congenital
Patient-Reported Outcomes in Adults With Congenital Heart Disease
The purpose of this study is to examine the differences in perceived health, psychosocial functioning, behavioral outcomes and quality of life of adults with congenital heart disease who are living in different areas of the…
- Trial name
- APPROACH-IS (NCT02150603)
- Where
- 24 sites in United States, Argentina and 13 more
- Volunteers
- 4,000 people
- Sponsor
- Philip Moons
Lung Cancer
Intensified Follow-up of Lung Cancer Using Weekly Questionnaires Via the Internet
This randomized controlled trial (RCT) will test if weekly supplementary internet-based self-monitoring of 12 core symptoms can increase survival in Danish lung cancer patients during follow-up or maintenance treatment.
- Trial name
- ProWide (NCT03608410)
- Testing
- Weekly Internet based PRO questionnaires
- Where
- Denmark
- Volunteers
- 494 people
- Sponsor
- Regional Hospital West Jutland
Prostate Cancer Patients Treated by Radiotherapy
Two-fraction Proton Therapy With MRI Guidance for Prostate Cancer: A Phase II Trial
This study is testing a shorter treatment method for prostate cancer using proton therapy (PT), which is very precise and may cause fewer side effects compared to traditional radiation.
- Trial name
- PT2 (NCT07130682)
- Testing
- Pencil Beam Proton Therapy Treatment Machine
- Where
- Hong Kong
- Volunteers
- 35 people
- Sponsor
- Hong Kong Sanatorium & Hospital
Bladder Neoplasms
Bladder Cancer Patient-Reported Outcomes
The purpose of this study is to identify aspects of the bladder cancer (BlCa) survivorship experience that differ by clinical risk at diagnosis.
- Trial name
- NCT01090388
- Where
- United States
- Volunteers
- 108 people
- Sponsor
- Baylor College of Medicine
Stroke, Cerebral Infarction
Assessment of Patient Reported Health Status Questions Via Four Different Methods of Administration, in Stroke Survivors.
A Patient Reported Outcome Measure (PROM) is a questionnaire that asks patients for their views on their own health or the impact of healthcare they have received on their health and quality of life (RCN, 2011).
- Conditions
- Stroke, Cerebral Infarction, Cerebral Hemorrhage, Stroke Hemorrhagic
- Trial name
- NCT03177161
- Testing
- 15 Patient Reported Health Status Questions
- Where
- 4 sites in United Kingdom
- Volunteers
- 472 people
- Sponsor
- Dr Jonathan Hewitt
Chronic Liver Disease (CLD), Liver Transplantation
Patient Reported Outcomes In Liver Biopsy (EUS vs. Percutaneous)
Patient Experience in Endohepatology Liver biopsy is a crucial procedure for the diagnosis and/or staging of liver diseases. Common indications for non-targeted biopsies include unexplained elevated liver function tests (LFTs)…
- Conditions
- Chronic Liver Disease (CLD), Liver Transplantation, Cirrhosis
- Trial name
- PRO-LIVER (NCT07506642)
- Testing
- EUS Liver Biopsy, Percutaneous Liver Biopsy
- Where
- Germany
- Volunteers
- 102 people
- Sponsor
- University Hospital Muenster
Multidrug Resistant Tuberculosis
Patient-reported Experiences and Quality of Life Outcomes in the TB-PRACTECAL Clinical Trial
PRACTECAL-PRO is a sub-study of a TB-PRACTECAL clinical trial for multidrug resistant Tuberculosis. It evaluates the effectiveness of TB-PRACTECAL interventions from the patient perspective in terms of their quality of life…
- Trial name
- PRACTECAL-PRO (NCT03942354)
- Testing
- Bedaquiline, Pretomanid, Moxifloxacin
- Where
- 6 sites in Belarus, South Africa and 1 more
- Volunteers
- 137 people, healthy volunteers welcome
- Sponsor
- Medecins Sans Frontieres, Netherlands
Breast Cancer
Patient-Reported Outcome and Safety Between Preoperative and Postmastectomy Radiotherapy in DIEP Flap Reconstruction
This study is the first prospective randomized study assessing the patient-reported outcomes and safety outcomes between preoperative and postmastectomy radiotherapy in locally advanced breast cancer patients with immediate…
- Trial name
- CAPPELLA (NCT05512286)
- Testing
- Preoperative radiotherapy, Postmastectomy radiotherapy
- Where
- 6 sites in China
- Volunteers
- 80 people
- Sponsor
- Fudan University
Breast Cancer
Developing a New Questionnaire About Patient Expectations of Breast Conserving Therapy
The purpose of this study is to develop a questionnaire to measure patient expectations of breast-conserving therapy (breast-conserving surgery and radiation).
- Trial name
- NCT02753673
- Testing
- qualitative interviews with patients, questionnaires
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Multiple Sclerosis, Relapsing-Remitting, Relapsing-Remitting Multiple Sclerosis
Effectiveness of DMF (Dimethyl Fumarate) and Its Impact on PROs (Patient Reported Outcomes) in Treatment-Naive or Suboptimal IFN (Interferon) or GA (Glatiramer Acetate) Responders With RRMS (ImPROve)
The primary objective of the study is to estimate the annualized relapse rate (ARR) over a 12-month period in patients with Relapsing-Remitting Multiple Sclerosis (RRMS) who are treated with dimethyl fumarate (DMF) as their…
- Trial name
- IMPROVE (NCT02323269)
- Testing
- dimethyl fumarate
- Where
- 10 sites in Canada
- Volunteers
- 24 people
- Sponsor
- Biogen
Nasal Polyps
Qualitative Analysis of Subject Experience of Nasal Polyps
Nasal polyposis is a chronic inflammatory disease of the nose and sinuses. GlaxoSmithKline (GSK) is embarking on a clinical program to assess treatment of severe, recurrent nasal polyps with an anti-interleukin-5 (anti-IL5)…
- Trial name
- NCT03221192
- Testing
- VAS questionnaire, SNOT-22 questionnaire, Data capture app
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- GlaxoSmithKline
Knee Osteoarthritis, Multimorbidity
Preoperative Multimorbidity and Functional Recovery After Total Knee Arthroplasty
This prospective observational cohort study aims to investigate the association between preoperative multimorbidity burden and functional recovery after primary total knee arthroplasty (TKA) in patients with knee osteoarthritis.
- Trial name
- NCT07882316
- Where
- Turkey (Türkiye)
- Volunteers
- 230 people
- Sponsor
- Balikesir Ataturk City Hospital
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