Clinical trials: Patient-centered Care
Intensive Care
Crystalloid Versus Hydroxyethyl Starch Trials
The aim of this study is to determine whether patients in the Intensive Care Unit who receive fluid resuscitation with either hydroxyethyl starch (a synthetic colloid solution) or saline (a salt solution), have an increased rate…
- Trial name
- CHEST (NCT00935168)
- Testing
- 6% Hydroxy-ethyl starch (130/0.4), Saline
- Where
- Australia
- Volunteers
- 7,000 people
- Sponsor
- The George Institute
Renal Replacement Therapy, Renal Dialysis
A Clinical Trial of IntensiVE Dialysis
This study will assess clinical outcomes of extended weekly hours of haemodialysis (>= 24 hours per week) compared with standard hours of haemodialysis (<=18 hours/week) in people with ESKD.
- Conditions
- Renal Replacement Therapy, Renal Dialysis, End Stage Kidney Disease, End Stage Renal Disease
- Trial name
- ACTIVE (NCT00649298)
- Testing
- haemodialysis
- Where
- 40 sites in Australia, Canada and 2 more
- Volunteers
- 200 people
- Sponsor
- The George Institute
Stroke, Activities of Daily Living
Instrumental Activities of Daily Living Approach in Home Environment for Patients With Stroke
The purpose of this study was to conduct a randomized clinical trial. Implement instrumental daily activities of daily living (A-IADL) in home rehabilitation.
- Trial name
- NCT04399759
- Testing
- Approach-Instrumental Activities of Daily Living, Home health education
- Where
- Taiwan
- Volunteers
- 27 people
- Sponsor
- National Taipei University of Nursing and Health Sciences
Brain Tumours
Investigating Visual Verticality Disorder and Lateropulsion in a Neurosurgical Cohort of Patients With Brain Tumours
The overall objective of this research is to investigate the clinical characteristics pre- and post-brain tumour resection with a focus on visual verticality disorder, and lateropulsion, including neuroimaging analysis, of a…
- Trial name
- NCT06951659
- Where
- Australia
- Volunteers
- 100 people
- Sponsor
- The University of Western Australia
Alzheimer Disease
Sensory Support Care for Elderly Patients Suffering From Alzheimer'S-type Neurodegenerative Disease
The main objective of this study is to evaluate the effect of 3 months of "Snoezelen-type" multi-sensory care sessions on NeuroPsychiatric Inventory Questionnaire (NPI-Q) scores for patients with Alzheimer's-type…
- Trial name
- SensiCare (NCT01819714)
- Testing
- Multi-sensory supportive care
- Where
- France
- Volunteers
- 31 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Delirium, Agitation
The Effectiveness of Acupuncture for Complications in Critically Ill Patients
Introduction: Intensive care unit (ICU) is a special department in the health care facility. Although with high development of modern medicine nowadays, the average mortality rate in ICU is still around 7 to 20 %.
- Conditions
- Delirium, Agitation, Arrhythmia, Feeding Intolerance
- Trial name
- NCT04950738
- Testing
- pess tack acupuncture
- Volunteers
- 80 people
- Sponsor
- China Medical University Hospital
Unresectable Locally Advanced Urothelial Cancer, Metastatic Urothelial Cancer
Study of Durvalumab Given With Chemotherapy, Durvalumab in Combination With Tremelimumab Given With Chemotherapy, or Chemotherapy in Patients With Unresectable Urothelial Cancer
This is a randomized, open-label, controlled, multi-center, global Phase III study to determine the efficacy and safety of combining durvalumab ± tremelimumab with standard of care (SoC) chemotherapy (cisplatin + gemcitabine or…
- Trial name
- NILE (NCT03682068)
- Testing
- Durvalumab, Tremelimumab, Cisplatin + Gemcitabine
- Where
- 222 sites in United States, Argentina and 20 more
- Volunteers
- 1,246 people
- Sponsor
- AstraZeneca
Cancer
A New Psychotherapy Intervention for Older Cancer Patients
This study is being done to see if a new psychotherapy intervention called Cancer and Aging: Reflections for Elders (CARE) can effectively treat depression and distress in older cancer patients.
- Trial name
- NCT04452825
- Testing
- Cancer and Aging: Reflections for Elders (CARE) Intervention, Social Work and Supportive Counseling (SWSC) Intervention
- Where
- United States
- Volunteers
- 459 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Chronic Pain, Central Sensitisation
Clinical Trial on Deprescribing Associated With a Psychoeducational Program Using Virtual Reality for Patients With Chronic Pain and Central Sensitization
This clinical trial evaluates the effectiveness of the REDOCVR program, an interdisciplinary, psychoeducational intervention designed to support deprescribing of chronic pain medications in primary care.
- Conditions
- Chronic Pain, Central Sensitisation, Opioid-Related Disorders, Patient Empowerment
- Trial name
- REDOCVR_AC (NCT06964360)
- Testing
- REDOCVR Psychoeducational Program, Standard Educational Materials
- Where
- 4 sites in Spain
- Volunteers
- 174 people
- Sponsor
- Badalona Serveis Assistencials
Stroke, Patient Education
Impact of a Nursing Educational Consultation on the Patient's Adherence to Their Post-stroke Care Plan.
This prospective, single-center, randomized study will evaluate the impact of implementing an educational nursing consultation at the end of hospitalisation for stroke patients returning home on overall adherence to…
- Trial name
- ICEIPAVC (NCT07524036)
- Testing
- nursing educational consultation
- Where
- France
- Volunteers
- 300 people
- Sponsor
- University Hospital, Bordeaux
Cancer Patients
A Patient Consensus for the Research in Supportive Care in French Cancer Care Centers: the CyPRES Project
In oncology a number of supportive care therapies are proposed to patients. This study will identify the different therapies and prioritize these therapies from the patients' perspectives.
- Trial name
- CyPRES (NCT03320161)
- Where
- 58 sites in France, Martinique
- Volunteers
- 604 people
- Sponsor
- UNICANCER
Diabetic Foot Ulcer
Evaluation of AUP12602-C as New Topical Treatment for DFUs (DIAMEND STUDY)
This is a phase 2 study performed in diabetic foot ulcer (DFU) patients with chronic non-healing, neuro-ischemic wounds to investigate the safety, tolerability and efficacy of AUP1602-C.
- Trial name
- NCT06111183
- Testing
- AUP1602-C
- Where
- 10 sites in Germany, Italy and 1 more
- Volunteers
- 64 people
- Sponsor
- Aurealis Oy
Acute Myeloid Leukemia
A Patient-Centered Communication Tool (UR-GOAL) Versus Usual Care for Older Patients With Acute Myeloid Leukemia, Their Caregivers, and Their Oncologists
The objective of this study is to evaluate the preliminary efficacy of the UR-GOAL tool in improving shared decision making and communication between older patients with AML and their oncologists in a pilot randomized trial.
- Trial name
- UR-GOAL 2 (NCT05335369)
- Testing
- UR-GOAL
- Where
- United States
- Volunteers
- 161 people
- Sponsor
- University of Rochester
Urinary Incontinence
Outcomes of Urinary Incontinence Treatment in Primary Care: APP Co-Management and Electronic Consult
The burden of urinary incontinence (UI) on American women is immense in both human and financial terms, and continues to rise with the aging US population.
- Trial name
- OUTPACE (NCT06040645)
- Testing
- APP Co-management, E-consult
- Where
- 3 sites in United States
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Older Adults With Complex Care Needs
Digital Bridge: Using Technology to Support Patient-centered Care Transitions From Hospital to Home
Older adults who live with multiple chronic conditions are more likely to experience frequent admissions and discharges from hospital. These transitions are often challenging and leave people at risk of readmission.
- Trial name
- DB (NCT04287192)
- Testing
- Digital Bridge:Tool Intervention
- Where
- Canada
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Mount Sinai Hospital, Canada
Enteral Feeding Intolerance, ICU
Transcutaneous Auricular Stimulation Targeting Enteral Feeding Intolerance
This study will test whether electrical stimulation applied to the outer ear can improve tolerance of tube feeding in critically ill adults in the intensive care unit (ICU).
- Trial name
- TASTE-FI (NCT07854236)
- Testing
- Transcutaneous auricular vagus nerve stimulation
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Chronic Heart Failure
Hospital-Community-Family-Care Management Platform for Chronic Heart Failure
The purpose of this study is to determine whether the Hospital-Community-Family-Care Management Platform for Chronic Heart Failure reduces the mortality, readmission rates and costs of the subjects with CHF.
- Trial name
- HCF-CMP-CHF (NCT02029287)
- Testing
- Hospital-Community-Family-Care Management Platform Online, Subjects with CHF via conventional clinic visit according to the latest relevant guidelines
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- Xiang Gu
Ventilator Associated Pneumonia, Aspiration
Ventilator Aspiration With PneuX (PneuX vs Standard Care Feasibility RCT)
This is a single centre, open-label, feasibility randomised controlled trial. The study aims to assess the feasibility of conducting an RCT to compare the PneuX ETT with standard care in hospitalised patients requiring mechanical…
- Conditions
- Ventilator Associated Pneumonia, Aspiration, Infections, Ventilator Lung
- Trial name
- VAP-X (NCT05410106)
- Testing
- PneuX Endotracheal Tube, Standard care (Taperguard, Covidien)
- Where
- United Kingdom
- Volunteers
- 50 people
- Sponsor
- Cardiff and Vale University Health Board
Dementia, Alzheimer Disease
Patient-Centered Dementia Care Practice Coaching Intervention
The goal of this clinical trial is to compare staff outcomes in long-term care communities who participate in the intervention versus those who do not. The main questions it aims to answer are: 1.
- Trial name
- DCPR_CC3 (NCT06249204)
- Testing
- Coaching Group
- Where
- United States
- Volunteers
- 449 people, healthy volunteers welcome
- Sponsor
- Alzheimer's Disease and Related Disorders Association, Inc
Carotid Stenosis
Lifestyle Modification Programme for Patients With Asymptomatic Carotid Artery Stenosis
This study randomises patients with patients with asymptomatic carotid artery stenosis, to be managed either by providing an intensive 12-week lifestyle modification programme, or standard healthcare.
- Trial name
- NCT03929354
- Testing
- Risk Factors Modification Programme, Standard Care
- Where
- Ireland
- Volunteers
- 208 people
- Sponsor
- Western Vascular Institute, Ireland