Clinical trials: Patient-controlled Intravenous Analgesia
Obese Patients
External Oblique Intercostal Block With or Without Intravenous Lidocaine Infusion for Analgesia in Patients Undergoing Gastric Bypass Surgery
Adding a perioperative lidocaine infusion (1.5 mg/kg loading + 1.5 mg/kg/h) to bilateral EOIB and low dose fentanyl loading reduces intraoperative fentanyl consumption (ANI guided rescue) compared to placebo, without increasing…
- Trial name
- NCT07809425
- Testing
- Investigatore hypothesize that adding a perioperative lidocaine infusion (1.5 mg/kg loading + 1.5 mg/kg/h) to bilateral EOIB and low dose fentanyl loading reduces intraoperative fentanyl consumption., Bilateral EOIB + fentanyl 1 μg/kg loading + normal saline loading (equivalent volume) + normal saline infusion (equivalent rate).
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Menoufia University
Colorectal Neoplasms
Safety and Efficacy Study of Intravenous Lidocaine After Colorectal Surgery: LIDOREHAB
The purpose of this study is to check if lidocaine intravenous administration during surgery and 24 hours after surgery, associated with standardised management of the patient, helps to accelerate recovery and to improve the…
- Trial name
- NCT00236249
- Testing
- Lidocaine
- Where
- France
- Volunteers
- 110 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Hip Fractures, Analgesia
Comparison of the Efficiency of Femur Nerve Block and Intravenous Analgesia Treatment in Hip Fracture Patients
It is well-established that hip fractures impose a significant medical, socioeconomic, and financial burden. In the elderly population, the associated mortality and morbidity are particularly pronounced: within one year following…
- Conditions
- Hip Fractures, Analgesia, Femoral Nerve
- Trial name
- NCT06862154
- Testing
- IV Analgesia- Fentanyl, Femoral Nerve Block
- Where
- Turkey (Türkiye)
- Volunteers
- 104 people
- Sponsor
- Marmara University
Lung Diseases
ESPB Versus INB With PCIA in Video-assisted Thoracic Surgery
A randomized prospective trial to test the non-inferiority of erector spinae plane block (ESPB) in comparison with intercostal nerve block combined with patient-controlled intravenous analgesia in Thoracoscopic lung surgery
- Trial name
- NCT03682354
- Testing
- Intercostal Nerve Block with PCIA, Erector Spinae Plane Block (ESPB)
- Where
- China
- Volunteers
- 70 people
- Sponsor
- Peking University Third Hospital
Bariatric Surgery Candidate, Bariatric Bowel Surgery
Intravenous Lidocaine for Post-Operative Pain Control in Patients Undergoing Bariatric Bowel Surgery
Currently, there are no studies that address the optimum dosage of lidocaine for surgical procedures. Lidocaine is a local anesthetic that is injected to induce anesthesia.
- Trial name
- BSurg (NCT03095404)
- Testing
- Low Dose Lidocaine, High Dose Lidocaine
- Sponsor
- McMaster University
S-ketamine, Analgesia, Patient-Controlled
The Effect of S-ketamine Combined With Sufentanil for Postoperative Analgesia in Patients Following Cesarean Section
This randomized controlled trial is designed to investigate the effect of low-dose of S-ketamine combined with sufentanil for postoperative patient-controlled intravenous analgesia in patients following cesarean section.
- Conditions
- S-ketamine, Analgesia, Patient-Controlled, Cesarean Section
- Trial name
- NCT05299866
- Testing
- S-ketamine
- Where
- China
- Volunteers
- 216 people
- Sponsor
- Ling Dong
Pain, Postoperative
A Comparison of the Safety and Effectiveness of Two Forms of Patient-controlled Pain Medication Used After Scheduled Abdominal or Pelvic Surgery: The Fentanyl Transdermal System Versus the Morphine Intravenous Pump
The purpose of this study is to compare two pain medications delivered by two different forms of patient-controlled pain management systems: the Fentanyl HCl Patient-Controlled Transdermal System (E-TRANS fentanyl) and the…
- Trial name
- NCT00266539
- Testing
- E-TRANS Fentanyl hydrochloride; Morphine
- Volunteers
- 506 people
- Sponsor
- Alza Corporation, DE, USA
Pancreatic Cancer, Biliary Tract Neoplasms
Analgesic Efficacy After Pancreatobiliary Surgery: Intravenous Versus Patient-controlled Epidural
Prospective, single institute based, open label, double arm, randomized controlled trial Hypothesis: Pain control after resection of hepatobiliary tumors in patients with PCEA is more effective than in patients with IV-PCA.
- Trial name
- NCT04352023
- Testing
- Patient-controlled analgesia
- Where
- South Korea
- Volunteers
- 110 people
- Sponsor
- National Cancer Center, Korea
Analgesia, Patient-Controlled
Oxycodone and Sufentanil for Analgesia in Hip Surgery
We design this randomized controlled trial to compare the safety and efficacy of Oxycodone and Sufentanil for postoperative patient-controlled analgesia in patients undergoing hip surgery, with a view to finding the optimal…
- Trial name
- NCT03685188
- Testing
- Oxycodone Hydrochloride, Sufentanil Citrate
- Where
- China
- Volunteers
- 570 people
- Sponsor
- West China Hospital
Nausea, Vomiting
Effect of Intravenous Patient-controlled Analgesia (IV-PCA) With Fentanyl in Adults for Acute Postoperative Pain Control
In this retrospective study, the investigators examined incidence and risk factors of postoperative nausea and vomiting (PONV) in patients with fentanyl-based intravenous patient-controlled analgesia (IV-PCA).
- Trial name
- NCT01527890
- Testing
- Fentanyl
- Where
- South Korea
- Volunteers
- 2,000 people
- Sponsor
- Yonsei University
Pain, Inflammation
Efficacy and Safety of Postoperative Intravenous Parecoxib Sodium Followed by Oral Celecoxib in Osteoarthritis Patients
In mainland China, knee Osteoarthritis (OA) is the leading cause of disability in older persons. Total knee arthroplasty (TKA) is now generally regarded by orthopaedic surgeons and patients as an effective treatment for end-stage…
- Trial name
- NCT02198924
- Testing
- Parecoxib and Celecoxib
- Where
- China
- Volunteers
- 246 people
- Sponsor
- Peking Union Medical College Hospital
General Anesthesia, Laparoscopic Cholecystectomy
Hypokalemia and Intravenous Patient Controlled Analgesia
The increase in stress hormone level and hyperventilation caused by the postoperative pain may contribute to the development of hypokalemia during postoperative period.
- Trial name
- NCT01269099
- Testing
- IV-PCA, Control
- Where
- South Korea
- Volunteers
- 50 people
- Sponsor
- Seoul Medical Center
Postoperative Pain, Bariatric Surgery Candidate
Intravenous Ibuprofen Versus Ketorolac in Bariatric Surgery
The aim of the current study is to compare the analgesic effects of both drugs in patients with obesity undergoing bariatric surgery.
- Trial name
- NCT05801900
- Testing
- Ketorolac group, Ibuprofen group
- Where
- Egypt
- Volunteers
- 116 people
- Sponsor
- Cairo University
Postoperative Pain Management After Total Hip Arthroplasty
Treatment of Postoperative Pain After Total Hip Arthroplasty Using Intravenous Lidocaine Infusion
This study will focus on patients undergoing total hip arthroplasty and Loma Linda University Medical Center \& East Campus. These patients will be randomized to receive a low dose lidocaine infusion or placebo, in addition to…
- Trial name
- NCT01108562
- Testing
- Lidocaine, Normal Saline
- Volunteers
- healthy volunteers welcome
- Sponsor
- Loma Linda University
Postoperative Nausea and Vomiting
Effect of Ketamine Added to Intravenous Patient-controlled Analgesia on Postoperative Pain, Nausea and Vomiting in Patients Undergoing Lumbar Spinal Surgery
Ketamine added to intravenous patient-controlled analgesia may be effective on prevention of postoperative nausea and vomiting by reducing opioid requirement after surgery.
- Trial name
- NCT01394406
- Testing
- Ketamine, Saline
- Where
- South Korea
- Volunteers
- 50 people
- Sponsor
- Yonsei University
Pain
Effects of Continuous Nerve Block vs Single Injection Block With PCA vs PCA on Pain and Function After Knee Replacement
The purpose of this study is to compare the effectiveness of three analgesia techniques on pain relief and functional recovery after knee replacement: continuous femoral nerve block vs single-injection femoral nerve block with…
- Trial name
- PCA (NCT01187537)
- Testing
- Continuous Femoral Nerve Block
- Where
- Singapore
- Volunteers
- 200 people
- Sponsor
- Tan Tock Seng Hospital
Postoperative Pain, Quality of Recovery (QoR-15)
MAG-PAIN - MAGnesium for Postoperative Analgesia In the Newly Delivered
The study aims to investigate whether a commonly used medicine, magnesium, can help reduce pain after a Caesarean section. A total of 150 participants will be included.
- Conditions
- Postoperative Pain, Quality of Recovery (QoR-15), Pain Prediction, Magnesium Sulfate
- Trial name
- MAG-PAIN (NCT07528612)
- Testing
- Magnesium group
- Volunteers
- 150 people
- Sponsor
- Region Halland
Postoperative Delirium
Acetaminophen-Mannitol Injection and Postoperative Delirium
The aim of this multicenter randomized controlled study is to evaluate the effect of an intravenous acetaminophen-mannitol opioid-sparing analgesic strategy on the cumulative incidence of POD, compared with an intravenous…
- Trial name
- PAPOD-ES (NCT07235995)
- Testing
- Acetaminophen group, Sufentanil group
- Where
- China
- Volunteers
- 1,092 people
- Sponsor
- Xiangya Hospital of Central South University
Prostate Cancer
Comparison Between Conventional and Model-based Infusion Strategy of IV PCA in Patients Undergoing RALP
Comparing postoperative analgesics requirements and complications between conventional and model-based infusion strategy of intravenous patient-controlled analgesia in patients who undergoing robot assisted laparoscopic radical…
- Trial name
- NCT02402621
- Testing
- fentanyl
- Where
- South Korea
- Volunteers
- 111 people
- Sponsor
- Asan Medical Center
Pain, Postoperative
Randomized Study Comparing the Use of Epidural Analgesia to Intravenous Narcotics for Laparoscopic Colorectal Resection.
Laparoscopic colorectal surgery (LCS) has gained wide acceptance in the treatment of various pathology from diverticular disease to colon cancer.
- Trial name
- NCT02086123
- Testing
- Epidural Analgesia, Parenteral Analgesia (Intravenous)
- Where
- United States
- Volunteers
- 87 people
- Sponsor
- University of California, Irvine