Clinical trials: Patients After Cardiac Surgery
Cardiac Surgery
Relationship Between Microcirculatory Flow Alterations and Tissue Metabolism
The purpose of this study is to correlate microcirculatory flow and rectal anaerobe cellular CO2 production in patients after cardiac surgery. The hypothesis is that such a correlation exists.
- Trial name
- NCT00547859
- Where
- Netherlands
- Volunteers
- 30 people
- Sponsor
- Frisius Medisch Centrum
Patients With Coronary Artery Disease Scheduled for by Pass Surgery
Atrial Fibrillation and By-pass Surgery
The aim of the study is to evaluate whether combined therapy with beta-blocker, amiodarone and statine is better than beta-blocker alone for the prevention of atrial fibrillation after coronary by-pass surgery.
- Trial name
- NCT01955759
- Testing
- Amiodarone tab 200 mg x 3, rosuvastatin 20 mg tab x1, beta blockers Bisoprolol in adjusted dose
- Where
- Bosnia and Herzegovina
- Volunteers
- 260 people
- Sponsor
- Heart Center BH Tuzla
Fluid Overload, Cardiac Surgery
Fluid Responsiveness in Post-cardiac Surgery
the study aims to examine the validity of combined end-expiratory and end-inspiratory occlusion test and tidal volume challenge test for prediction of fluid responsiveness in immediate post-cardiac surgery patients
- Conditions
- Fluid Overload, Cardiac Surgery, Postoperative Complications
- Trial name
- NCT05957003
- Testing
- Combined end-expiratory occlusion and end-inspiratory occlusion test, Tidal volume challenge test
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Tanta University
Coronary Artery Disease
Effect of Intravenous Ferric Carboxymaltose on Hemoglobin Response and Transfusion in Patients With Iron Deficiency Anemia After Off-Pump Coronary Artery Bypass Grafting
In this prospective open-label randomized tral, 100 patients with elective off-pump coronary artery bypass (OPCAB) or minimal invasive direct coronary bypass (MIDCAB) surgery were enrolled.
- Trial name
- NCT04898569
- Testing
- Ferinject, Normal Saline Flush
- Where
- South Korea
- Volunteers
- 100 people
- Sponsor
- Yonsei University
Other Functional Disturbances Following Cardiac Surgery
Pilates-based Cardiopulmonary Physical Therapy for In-Patients After Cardiac Surgery
The purpose of this clinical trial is to evaluate the effect of pilates-based cardiopulmonary physical therapy (CPT) for in-patients after cardiac surgery.
- Trial name
- PBCPT (NCT02437240)
- Testing
- Pilates-based CPT, Traditional CPT
- Volunteers
- 140 people
- Sponsor
- National Yang Ming Chiao Tung University
Elderly Patients, Non-cardiac Surgery
Effects of Limb Remote Ischemic Preconditioning for Prevention of Delirium in Elderly Patients After Non-cardiac Surgery
To investigate whether limb remote ischemic preconditioning (LRIP) could safely decrease the incidence of delirium in elderly patients after non-cardiac surgery.
- Trial name
- LRIP-D (NCT03028389)
- Testing
- limb remote ischemic preconditioning(LRIP)
- Volunteers
- 611 people
- Sponsor
- Nanfang Hospital, Southern Medical University
AKI - Acute Kidney Injury, Cardiac Surgery
Urine Output Response to Fluid and Diuretic Therapy in Cardiac ICU Patients Monitored With FIZE kUO®
This prospective observational study evaluates the real-time urine output response to fluid therapy and diuretics in cardiothoracic intensive care unit (CTICU) patients monitored with the FIZE kUO® device.
- Conditions
- AKI - Acute Kidney Injury, Cardiac Surgery, Fluid Therapy, Hemodynamic Instability
- Trial name
- NCT07022314
- Testing
- FIZE kUO®
- Where
- Israel
- Volunteers
- 45 people
- Sponsor
- FIZE Medical ltd
Cardiac Study Patients
Back to Functional Life Following Cardiac Surgery
The investigators will monitor cardiac patients rehabilitation post op upon their pre op status.
- Trial name
- BTFL2012 (NCT01586585)
- Where
- Israel
- Sponsor
- Carmel Medical Center
Anesthesia, Regional, Pain, Postoperative
Pectoral-Intercostal Fascial Plane Block Study
Pain along the sternum following opening of the chest cavity, also known as post-sternotomy pain (PSP), is a common complication after heart surgery that is associated with several negative side effects.
- Trial name
- PIFB (NCT03729635)
- Testing
- Pectoral-intercostal fascial plane block (PIFB)
- Where
- Canada
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Heart Failure With Reduced Ejection Fraction
Respiratory Sinus Arrhythmia Pacing Post-CABG Surgery in Patients With HFrEF
The goal of this clinical trial is to test a new type of pacemaker in heart failure patients following a heart bypass operation.
- Trial name
- RSA-PACE (NCT06384963)
- Testing
- Atrial pacing with respiratory sinus arrhythmia (RSA) variability, Monotonic right atrial overdrive pacing
- Where
- 3 sites in Australia, New Zealand
- Volunteers
- 54 people
- Sponsor
- Ceryx Medical Australia
Patients Undergoing Cardiac Surgery With Cardiopulmonary Bypass
A Comparison Between 5% Albumin and 6% Hydroxyethyl Starch 130/0.4 in Priming Solution for Cardiopulmonary Bypass and Post-bypass Maintenance Fluid in High-risk Patients
It is advantageous to use 5% human albumin (HA) in patients undergoing cardiopulmonary bypass (CPB), because preexposure of the synthetic surfaces of the CPB circuit to albumin decreases coagulopathy, platelet aggregation, immune…
- Trial name
- NCT01644084
- Testing
- Hydroxyethyl starch 130/0.4
- Where
- South Korea
- Volunteers
- 54 people
- Sponsor
- Yonsei University
Coronary Bypass Graft Surgery, Atrial Fibrillation
Effect of Genetic Polymorphism on the Occurrence of Post-Operative Atrial Fibrillation After CABG
Postoperative Atrial Fibrillation (POAF) is one of the most common complications following coronary artery bypass grafting (CABG) occurring to 20% - 40% of patients.
- Trial name
- NCT03871647
- Testing
- Beta blocker
- Where
- Egypt
- Volunteers
- 256 people
- Sponsor
- Ain Shams University
Post-operative Cognitive Decline, Post-operative Delirium
Cardiac Surgery Neuroprotection Study in Elders
The goal of this study is to determine the potential ability of intranasal insulin to prevent post-operative cognitive decline and post-operative delirium in an elderly cardiac surgery population.
- Trial name
- CNS-Elders (NCT01561378)
- Testing
- Aspart insulin, Normal saline, Intranasal mucosal atomizer device
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Albert Einstein College of Medicine
Cardiomyopathy, Heart Failure, Congestive
Biventricular Pacing In Patients With Left Ventricular Dysfunction After Cardiovascular Surgery
Congestive heart failure (CHF) is a medical condition that is due to left ventricular systolic dysfunction (LVSD). LVSD is a decreased ability of the heart to pump blood forward.
- Conditions
- Cardiomyopathy, Heart Failure, Congestive, Thoracic Surgery
- Trial name
- NCT00321295
- Testing
- Atrial synchronous bi-ventricular pacing
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Corewell Health East
Coronary Artery Disease
Dynamic Arterial Elastance for Prediction of Vasopressor Requirement After Anesthesia Induction in Elective On-Pump CABG
This study aims to determine whether dynamic arterial elastance (EaDyn), measured after anesthesia induction, can predict the need for vasopressor treatment in patients undergoing elective on-pump coronary artery bypass graft…
- Trial name
- NCT07871201
- Testing
- No intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people
- Sponsor
- Elzem SEN
Severe Aortic Valve Stenosis, Severe Mitral Valve Regurgitation
Post Spinal Hemodynamic Changes in Aortic Stenosis and Mitral Regurgitation by VIS Index and Echocardiography
This study will assess hemodynamic changes induced after spinal anesthesia by evaluating vasopressor inotropic requirements and variations in echocardiographic parameters in patients having severe aortic stenosis or severe mitral…
- Trial name
- NCT06156592
- Testing
- Cardiac valve replacement surgery under high spinal anesthesia combined with light general anesthesia
- Where
- Canada
- Volunteers
- 44 people
- Sponsor
- University of Manitoba
Carotid Stenosis
Platelet Inhibition and Transcranial Doppler (TCD)-Detected Microemboli During and After Carotid Artery Stenting (CAS) in Asymptomatic Patients Prior to Cardiac Surgery
As with coronary artery stenting, activation and embolisation of platelets occurs with carotid artery stenting (CAS). Based on promising data on the use of clopidogrel plus aspirin in coronary stenting this dual antiplatelet…
- Trial name
- IMPACT (NCT01146301)
- Testing
- Clopidogrel
- Where
- Netherlands
- Sponsor
- R&D Cardiologie
Enhanced Recovery, Prehabilitation
Prehabilitation in Adult Patients Following Selective Cardiac Surgery: A Randomized Controlled Trial
Aim: To determine the impact of an evidence-based comprehensive prehabilitation (EBCPrehab) program on pre- and postoperative capacity, functional capacity and health related quality of life (HRQoL) in patients awaiting elective…
- Conditions
- Enhanced Recovery, Prehabilitation, Cardiac Surgery
- Trial name
- NCT05503004
- Testing
- Prehabilitation, Standard care
- Where
- China
- Volunteers
- 160 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Postoperative Complications
Cardiopulmonary Exercise Testing in Cardiosurgery Patients
Cardiopulmonary exercise testing (CPET) is considered to be a gold standard in pre-operative risk assessment and stratification of high risk patients scheduled for major surgery.
- Trial name
- NCT06702059
- Testing
- Cardiopulmonary exercise testing
- Where
- 2 sites in Czechia
- Volunteers
- 130 people
- Sponsor
- St. Anne's University Hospital Brno, Czech Republic
Post Cardiac Surgery
Minimal Volume for Fluid Challenge in Post-operative Patients
This study evaluate the effect of different doses of crystalloids on the changes on cardiac output (CO) and on the proportion of responders and non-responders and aims to determine the minimal volume required to increase the mean…
- Trial name
- NCT02569008
- Testing
- Fluid challenge with Compound Sodium Lactate
- Where
- United Kingdom
- Volunteers
- 80 people
- Sponsor
- St George's, University of London