Clinical trials: Patients After Cardiac Surgery
Coronary Artery Bypass Surgery
Study of Role of Blood Microvescicles and Exosomes in Patients With Graft Occlusion After Aortocoronary Bypass Surgery
Coronary artery bypass graft (CABG) surgery is still the standard treatment of coronary revascularization for patients with severe coronary artery disease (CAD).
- Trial name
- MVBYPASS (NCT05411445)
- Where
- Italy
- Volunteers
- 300 people
- Sponsor
- Maria Cecilia Hospital
Congenital Disorders
Patients With NMDA Biomarker Data Following Cardiac Surgery
The purpose of this current retrospective study is to perform follow-up analysis on the 22 children from the study # 621-2004 It is important to examine whether an elevated biomarker of brain ischemia before and/or following…
- Trial name
- NCT00366886
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Children's Healthcare of Atlanta
Atrial Fibrillation
Vitamin C and Atrial Fibrillation After Cardiac Surgery
The purpose of this study is to determine if vitamin C decreases the chance of developing atrial fibrillation, a type of arrhythmia or irregular heartbeat, following cardiac surgery.
- Trial name
- NCT01580683
- Testing
- Ascorbic Acid
- Where
- United States
- Sponsor
- Regional Hospital of Scranton
Patient After Cardiac Valve Surgery, Patient With Prolonged Mechanical Ventilation
The Association Between Intestinal Perfusion and Prolonged Mechanical Ventilation in Patients After Cardiac Valve Surgery
Background This study aimed to confirm that alterations in Doppler parameters of superior mesenteric artery(SMA) blood flow caused by intestinal hypoperfusion are associated with prolonged mechanical ventilation(PMV) in patients…
- Trial name
- NCT05500495
- Testing
- no intervention
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Peking Union Medical College Hospital
Cardiac Surgery Requiring Cardiopulmonary Bypass
Vancomycin Concentration Analysis in Post-Cardiac Surgery Patients
The benefits of antimicrobial prophylaxis for cardiac surgery have been clearly demonstrated in placebo-controlled studies. Prophylactic intravenous antibiotics are therefore administered, with agent selection directed against…
- Trial name
- NCT07087301
- Testing
- subtherapeutic concentration risk group
- Where
- China
- Volunteers
- 350 people
- Sponsor
- Pengqiang Du
Coronary Disease
Circulatory Oscillations in Post Cardiac Surgery Patients
In this observational study investigators examine the presence of circulatory oscillations in blood pressure, heart rate, and doppler laser flow before and after planned cardiac surgery.
- Trial name
- NCT02765607
- Testing
- Heart surgery
- Where
- Norway
- Volunteers
- 20 people
- Sponsor
- St. Olavs Hospital
Patients Undergoing Cardiac Surgery Using Cardiopulmonary Bypass
FiO2 and Outcomes After Cardiac Surgery With Cardiopulmonary Bypass
Conventionally, a relatively high level of fraction of inspired oxygen (FiO2) has been used for secure a margin of safety in patients undergoing cardiac surgery using cardiopulmonary bypass (CPB).
- Trial name
- NCT03939832
- Testing
- Fraction of inspired oxygen level
- Where
- South Korea
- Sponsor
- Seoul National University Hospital
Chronic Postoperative Pain
PANDORA: Paravertebral AdjuNctive DexamethasOne Palmitate Reducing Chronic Pain After Caridiac Surgery
The goal of this single-center, prospective, double-blind randomized controlled clinical trial is to explore preventive interventions for chronic postoperative pain (CPSP) in patients undergoing minimally invasive cardiac…
- Trial name
- NCT05920967
- Testing
- Dexamethasone Palmitate, Dexamethasone Sodium Phosphate
- Where
- China
- Volunteers
- 562 people
- Sponsor
- Xijing Hospital
Thoracic Surgery, Postoperative Period
Efficacy of Triburter on Respiratory Muscle Function in Patients After CABG in Cardiac Rehabilitation Phase II
Post-surgery patients have muscle impairments, especially in the respiratory muscles, because the anesthesia, surgical incision, mechanical ventilation, pain, and prolonged postures, affect the mechanical condition of respiratory…
- Conditions
- Thoracic Surgery, Postoperative Period, Weakness, Muscle
- Trial name
- NCT05496049
- Testing
- Triburter, Incentive spirometry
- Where
- Colombia
- Volunteers
- 30 people
- Sponsor
- Fundación Cardiovascular de Colombia
Pulmonary Hypertension, Mitral Valve Surgery
PDEI Following Mitral Valve Surgery in Patients With Pulmonary Hypertension
A randomized, placebo controlled, single center clinical trial for evaluation of efficacy and safety of Sildenafil administration in the cardiac ICU following Mitral Valve (MV) Surgery in patients with pre-operative Significant…
- Trial name
- NCT02378649
- Testing
- Sildenafil
- Where
- Israel
- Volunteers
- 60 people
- Sponsor
- Dr. Robert Klempfner Heart Rehabilitation Institute
Coronary Artery Disease
Long-term Comparison of Stenting Versus Off-pump Coronary Bypass Surgery
The randomized comparison of two strategies in coronary revascularization: bypass surgery without the use of a heart lung machine and coronary stenting procedure.
- Trial name
- OCTOSTENT (NCT00975858)
- Testing
- Coronary Revascularization
- Where
- Netherlands
- Volunteers
- 280 people
- Sponsor
- UMC Utrecht
Patients Undergoing Valvular Heart Surgery
Association Between Post-operative Anemia and Mortality After Valvular Heart Surgery
The investigators aimed to evaluate whether postoperative anemia can predict 1-year mortality after valvular heart surgery independent of preoperative anemia.
- Trial name
- NCT06647758
- Where
- South Korea
- Volunteers
- 3,000 people
- Sponsor
- Yonsei University
Gastric Ulcer Induced by Antiplatelet Agent, Ulcer of the Gastrointestinal Tract
Proton Pump Inhibitor Prevent Dual Antiplatelet Agents Induced Gastrointestinal Ulcer After Coronary Artery Bypass Graft
The purpose of this study is to determine whether 12-month prophylactic treatment with pantoprazole is superior to 1-month therapy without major cardiovascular events (MACE) increased significantly, in prevention of dual…
- Conditions
- Gastric Ulcer Induced by Antiplatelet Agent, Ulcer of the Gastrointestinal Tract, Proton Pump Inhibitor
- Trial name
- DACAB-GI-2 (NCT03038009)
- Testing
- Pantoprazole
- Where
- China
- Sponsor
- Ruijin Hospital
Tricuspid Atresia, Hypoplastic Left Heart Syndrome
Biomarker Study for Heart Failure in Children With Single Ventricle Physiology
The purpose of this study is to determine if children with heart disease where there is only one pumping chamber("ventricle") have proteins (biomarkers") in the blood that can be used to monitor the function of their heart.
- Conditions
- Tricuspid Atresia, Hypoplastic Left Heart Syndrome, Unbalanced AV Canal
- Trial name
- BHFSVP (NCT00571233)
- Where
- United States
- Volunteers
- 71 people
- Sponsor
- University of California, San Francisco
Myocardial Infarction
Predicting Myocardial Infarction After Abdominal Surgery: Clinical Scores & Biomarkers
All patients undergoing non-cardiac surgery who met the inclusion criteria underwent a preoperative evaluation using specific assessment tools.
- Trial name
- NCT06767943
- Testing
- 12-lead electrocardiography
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Benha University
Sedation After Cardiac Surgery
Investigation of Sedation Depth Via BIS Monitoring in ICU After Cardiac Surgery
This study is a non-interventional, observational research project focused on monitoring sedation levels in patients who have undergone cardiac surgery.
- Trial name
- BISICU (NCT07350109)
- Where
- 2 sites in Austria
- Volunteers
- 50 people
- Sponsor
- Medical University of Graz
Coronary Artery Bypass Surgery
Starch or Saline After Cardiac Surgery
When people undergo major surgery, they require intravenous supplementation of fluids for a number of reasons: to compensate for no oral intake to support blood pressure and organ function during and after surgery to replace lost…
- Trial name
- SSACS (NCT00964015)
- Testing
- 6% Hydroxyethyl Starch 130/0.4, 0.9% Normal Saline
- Where
- Canada
- Volunteers
- 69 people
- Sponsor
- London Health Sciences Centre
Delirium in Old Age, Delirium
PANDORA: Delirium Prevention After Cardiac Surgery Using IV Acetaminophen to Prevent Postoperative Delirium in Older Cardiac Surgical Patients
Our objective is to find an effective prophylactic intervention by evaluating IV acetaminophen's impact in reducing the frequency of postoperative delirium, one of the most common and detrimental complications of cardiac surgery…
- Conditions
- Delirium in Old Age, Delirium, Coronary Artery Disease
- Trial name
- PANDORA (NCT04093219)
- Testing
- IV acetaminophen
- Where
- 10 sites in United States
- Volunteers
- 901 people
- Sponsor
- Beth Israel Deaconess Medical Center
Pulmonary Hypertension
Does Oral Sildenafil (Viagra) Decrease Mean Pulmonary Artery Pressure After Cardiac Surgery?
Post-operative pulmonary hypertension is a risk factor for right ventricular failure and an increasing cause of morbidity and mortality in patients undergoing high-risk cardiac surgery.
- Trial name
- NCT00334490
- Testing
- Sildenafil
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- Unity Health Toronto
Heart Failure
Stimulation of the Diaphragm in Patients With Severe Heart Failure Following Heart Surgery
This study examines whether a permanent stimulation of the diaphragm improves left ventricular function in patients with severe heart failure following heart surgery.
- Trial name
- NCT00769678
- Testing
- Stimulation of the diaphragm
- Where
- Switzerland
- Volunteers
- 33 people
- Sponsor
- Luzerner Kantonsspital