Clinical trials: Patients After Cardiac Surgery
Hemodynamic Monitoring, ICU
Automated Inferior Vena Cava Collapsibility Index Fluid Responsiveness in Ventilated Patients After Cardiac Surgery.
Echocardiographic measurement of inferior vena cava (IVC) collapsibility index (CI) with automated software analyses has been introduced.
- Conditions
- Hemodynamic Monitoring, ICU, Cardiac Surgery
- Trial name
- NCT05283590
- Testing
- Automated echocardiographic inferior vena cava measurement
- Where
- Qatar
- Volunteers
- 50 people
- Sponsor
- Hamad Medical Corporation
Post Operative Pain
Comparison of PSB and RIFPB Combination With PSB and ESPB Combination in Cardiac Surgery With Sternotomy
The goal of this study is to compare the analgesic efficacy of the combination of PSB and RIFPB and the combination of PSB and ESPB in patients undergoing cardiac surgery with sternotomy.
- Trial name
- NCT06553573
- Testing
- Parasternal Block and Recto-İntercostal Fascial Plane Block, Parasternal Block and Erector Spinae Plane Block
- Volunteers
- 24 people
- Sponsor
- Cumhuriyet University
Surgical Procedure, Unspecified
VRES Study in Two Phases to Monitor Cardiac Surgical Patients Following Discharge From ICU
Failure to recognise deterioration early is a major cause of preventable deaths amongst hospital patients. The investigators wish to study whether continuous monitoring of 'vital signs' (pulse rate, breathing rate, and blood…
- Trial name
- VRES (NCT02427828)
- Testing
- Visensia Respiration Rate Estimation Service (VRES)
- Where
- United Kingdom
- Volunteers
- 208 people
- Sponsor
- OBS Medical Ltd
Post-Cardiac Surgery Patients
Value Analysis in Patients Undergoing Self-Management Training Using a Coagulometer
Prior research has not assessed the value of remote patient monitoring (RPM) systems for patients undergoing anticoagulation therapy after cardiac surgery.
- Trial name
- VAPUST (NCT06423521)
- Testing
- Standard of Care (SOC), Remote Patient Monitoring (RPM)
- Where
- Portugal
- Volunteers
- 28 people
- Sponsor
- Ana Rita Londral, PhD
Diaphragmatic Paralysis
Diaphragm Training Post-Cardiac Surgery
Diaphragm paralysis is a possible complication of cardiac surgery. The spontaneous recovery of the diaphragm mobility is slow and partial or absent in most cases.
- Trial name
- DIATRACS (NCT00597298)
- Testing
- Threshold
- Where
- Italy
- Volunteers
- 48 people
- Sponsor
- Ospedali Riuniti Trieste
Atrial Fibrillation, Post-Op Complication
Prevention of Postoperative Atrial Fibrillation (POAF) Using Intra-Pericardial Amiodarone
The purpose of this study is to evaluate the combination of CardiaMend, with the addition of amiodarone in the prevention of postoperative atrial fibrillation (POAF) in patients undergoing cardiac arterial bypass grafting (CABG)…
- Trial name
- NCT06063538
- Testing
- CardiaMend in Combination with Amiodarone
- Where
- United States
- Volunteers
- 63 people
- Sponsor
- University of Chicago
Aortic Aneurysm, Abdominal, Ventricular Arrythmia
Cardiac Complication After Vascular Surgery
The vascular surgery is a highest risk procedure when considering postoperative complications associated with the cardiovascular system. The leading clinical presentation is acute hemodynamic decompensation.
- Conditions
- Aortic Aneurysm, Abdominal, Ventricular Arrythmia, Peripheral Arterial Disease, Cardiac Complication
- Trial name
- CCVS (NCT03188341)
- Testing
- vascular surgery procedure
- Volunteers
- 100 people
- Sponsor
- Pomeranian Medical University Szczecin
Cardiac Surgery Associated - Acute Kidney Injury, Acute Kidney Injury
Association Between Liver Function Tests and Acute Kidney Injury in Cardiac Surgery Patients
A sudden decline in function of the kidneys is a common problem that can happen after heart surgery. It can have serious effects on a patient's recovery and long-term health, potentially leading to permanent kidney problems or…
- Trial name
- TransAKI (NCT06730854)
- Where
- Belgium
- Volunteers
- 3,415 people
- Sponsor
- University Hospital, Ghent
Left Ventricular Dysfunction, Quality of Recovery
Preoperative Maltodextrin's Effect on Cardiac Function in Cardiac Surgery
A randomized, controlled, double-blinded clinical trial evaluating the effect of the administration of a Maltodextrin solution on cardiac function in patients presenting for coronary artery bypass grafting surgery with a reduced…
- Conditions
- Left Ventricular Dysfunction, Quality of Recovery, Right Ventricular Dysfunction
- Trial name
- NCT05188222
- Testing
- Maltodextrin solution
- Where
- Canada
- Volunteers
- 70 people
- Sponsor
- Jewish General Hospital
Postoperative Vasoplegic Syndrome
Small Doses of Pituitrin Versus Norepinephrine for the Management of Vasoplegic Syndrome in Patients After Cardiac Surgery
Vasoplegic syndrome is a common complication after cardiac surgery. Low dose vasopressin can up-regulate blood pressure and improve clinical outcomes compared with norepinephrine (mainly acute kidney injury Anesthesiology 2017…
- Trial name
- NCT03106831
- Testing
- Pituitrin infusion, Norepinephrine infusion
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Beijing Anzhen Hospital
Ventilator-Induced Diaphragm Dysfunction
Study of TransAeris® System for Enhanced Recovery After Surgery in France
This study will be conducted as a randomized trial of the TransAeris system for the prevention and treatment of ventilator-induced diaphragm dysfunction (VIDD) in patients identified prior to surgery to be at greater risk of…
- Trial name
- ERAS (NCT05404477)
- Testing
- TransAeris System
- Where
- France
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Synapse Biomedical
Pneumothorax
Lung Ultrasound Versus Chest Radiography for Detection of Pneumothorax
Sunnybrook Health Sciences Center annually provides assistance to approximately 600 cardiac surgeries and 1500 trauma patients, many of whom require chest tubes to prevent blood and fluids from accumulating in the pleural…
- Trial name
- LUSvsCXR (NCT06022081)
- Testing
- Lung ultrasound to detect pneumothorax.
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- Sunnybrook Health Sciences Centre
Coronary Artery Disease
Home-Based Versus Center-Based Cardiac Rehabilitation After CABG Surgery
This randomized controlled trial was designed to compare the efficacy of a 12-week home-based telerehabilitation (HBTCR) program against traditional center-based cardiac rehabilitation (CBCR) and usual care in patients who have…
- Trial name
- NCT07243444
- Testing
- Structured Exercise Program, Standard Health Education
- Where
- China
- Volunteers
- 110 people
- Sponsor
- The First Hospital of Hebei Medical University
Delirium - Postoperative, Cardiac Surgery
Lemborexant to Prevent Post-operative Delirium in Cardiac Surgery Patients
Post-operative delirium is a common complication following cardiac surgery and is associated with increased 1 year mortality. Currently there are no drug therapies to prevent delirium.
- Conditions
- Delirium - Postoperative, Cardiac Surgery, Cardiac Surgery Subjects, Orexin Antagonist
- Trial name
- PROTEX (NCT06648681)
- Testing
- Lemborexant 5 mg
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- University of British Columbia
Heart Valve Disease
CopenHeartVR - Integrated Rehabilitation of Patients After Heart Valve Surgery
The aim of the study is to investigate the effect of an integrated rehabilitation programme, consisting of physical exercise training and psycho-educational consultations, for patients after heart valve surgery.
- Trial name
- CopenHeartVR (NCT01558765)
- Testing
- Integrated rehabilitation
- Where
- Denmark
- Volunteers
- 147 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Open Heart Surgery Patients
Quality of Life After Open Heart Surgery in Older Patients
Long term follow-up of nonagenarians who have undergone open heart procedures.
- Trial name
- NCT00248898
- Testing
- Cardiac Surgery
- Where
- United States
- Volunteers
- 49 people
- Sponsor
- Weill Medical College of Cornell University
Older Patients, Surgery
Long-term Follow-up of Dexmedetomidine-esketamine and tDCS for Neurocognitive Complications After Surgery
Neurocognitive complications, mainly delirium and neurocognitive disorders, are common cerebral complications in older patients after surgery and associated with worse long-term outcomes.
- Conditions
- Older Patients, Surgery, Dexmedetomidine, Esketamine
- Trial name
- NCT07576543
- Testing
- Dex-Esk, Active tDCS
- Where
- 6 sites in China
- Volunteers
- 1,996 people, healthy volunteers welcome
- Sponsor
- Peking University First Hospital
Coronary Artery Disease, Valvular Heart Disease
Efficacy of Sternum Guard in Post Cardiac Surgery Patient
This is a single-center, single-blind, randomized parallel superiority trial comparing two groups; Sternum GuardTM as the treatment arm and Bone Wax as the active control group.
- Conditions
- Coronary Artery Disease, Valvular Heart Disease, Congenital Heart Disease in Adolescence, Post Operative Wound Infection
- Trial name
- NCT05229276
- Testing
- Sternum Guard, Bone Wax
- Where
- Indonesia
- Volunteers
- 414 people
- Sponsor
- Universitas Indonesia
Post Operative Arrythmia
Impact of Ligament of Marshall Resection on Atrial Fibrillation Occurrence in Patients Undergoing Coronary Artery Bypass Grafting: A Randomized Controlled Trial
Background: 20-40% of patients with ischemic heart disease managed with coronary artery bypass grafting (CABG) surgeries face the risk of postoperative atrial fibrillation (POAF), which is a known hazardous outcome.
- Trial name
- NCT07492901
- Testing
- A standard on-pump coronary artery bypass grafting (ON-CAB), adjunctive LoM resection
- Where
- 2 sites in Egypt
- Volunteers
- 220 people
- Sponsor
- Kasr El Aini Hospital
Coronary Artery Bypass Graft Surgery, Mace
Discharge Planning Program for Post CABG Patients
The current study is utilizing a nurse led discharge program based on the Re-Engineered Discharge program (Project-RED) ( Agency of Healthcare Research and Quality [AHRQ], 2013) which is a package of services designed to minimize…
- Conditions
- Coronary Artery Bypass Graft Surgery, Mace, 30 Day Mortality
- Trial name
- NCT04527822
- Testing
- Nurse led discharge planning program
- Where
- Jordan
- Volunteers
- 174 people
- Sponsor
- University of Jordan