Clinical trials: Patients After Cardiac Surgery
Post-cardiac Surgery, Ventilator Weaning
Correlation Analysis Between Mostcare Parameters and Spontaneous Breathing Trial in Patients After Cardiac Surgery
Cardiac output (CO) monitoring is of primary importance in high-risk surgery and critically ill patients. Intermittent thermodilution (ThD) by means of a pulmonary artery catheter (PAC) was invasiveness, the occurrence of…
- Trial name
- NCT06230497
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Peking Union Medical College Hospital
Transthyretin Amyloidosis, Transthyretin Cardiac Amyloidosis
Prevalence of wtATTR-CM After Carpal Tunnel Release Surgery
Patients above the age of 60 will be recruited at their carpal tunnel release surgery. Biopsies will be taken from the wrist and examined for the presence of amyloid protein.
- Conditions
- Transthyretin Amyloidosis, Transthyretin Cardiac Amyloidosis, Wild-Type Transthyretin-Related (ATTR)Amyloidosis
- Trial name
- CACTuS2 (NCT04276220)
- Testing
- Tenosynovial biopsy
- Where
- Denmark
- Volunteers
- 109 people
- Sponsor
- Steen Hvitfeldt Poulsen
Postoperative Pain, Sternotomy
Effect of Elastic Therapeutic Taping on Post-Sternotomy Pain in Coronary Artery Bypass Graft Surgery
This research study aims to find out whether elastic therapeutic taping can help reduce pain after heart surgery, specifically coronary artery bypass grafting (CABG), which is done using a surgical cut through the breastbone…
- Conditions
- Postoperative Pain, Sternotomy, Pain Management, Coronary Artery Bypass
- Trial name
- NCT06910215
- Testing
- Elastic therapeutic taping, Therapeutic Taping on Non-Surgical Areas
- Where
- Turkey (Türkiye)
- Volunteers
- 195 people
- Sponsor
- Abant Izzet Baysal University
Coronary Artery Bypass Surgery, Coronary Heart Disease
An Efficacy and Safety Study for Nesiritide in Heart Failure Patients With Reduced Kidney Function Undergoing Coronary Artery Bypass Graft Surgery Requiring Cardiopulmonary Bypass (CPB Pump or Heart Lung Machine)
The purpose of this study is to assess whether nesiritide compared to placebo when given with standard of care therapies, helps preserve kidney function in heart failure (HF) patients undergoing heart bypass graft surgery that…
- Conditions
- Coronary Artery Bypass Surgery, Coronary Heart Disease, Coronary Artery Bypass Grafting, Cardiopulmonary Bypass
- Trial name
- NCT00530361
- Testing
- Nesiritide
- Sponsor
- Scios, Inc.
Post-Operative Atrial Fibrillation
Botulinum Toxin Type A (AGN-151607) for the Prevention of Post-operative Atrial Fibrillation in Adult Participants Undergoing Open-chest Cardiac Surgery (NOVA)
This was a multi-center, randomized, double-blind, placebo-controlled, parallel group, dose-ranging study to evaluate the efficacy and safety of botulinum toxin type A (AGN-151607) injections into the epicardial fat pads, foci of…
- Trial name
- NCT03779841
- Testing
- AGN-151607
- Where
- 32 sites in United States, Austria and 7 more
- Volunteers
- 323 people
- Sponsor
- AbbVie
Surgery
Association Between Perioperative Platelet Function and Major Adverse Perioperative Events
This study will examine the degree of blood thinning (platelet function) in patients coming for non-cardiac surgery on antiplatelet agents using platelet function tests called thromboelastography (TEG) and platelet mapping assay…
- Trial name
- NCT00901030
- Testing
- Blood drawn
- Where
- 3 sites in Canada
- Volunteers
- 250 people
- Sponsor
- McMaster University
Post-cardiac Surgery
Alternate Nostril Breathing on Cardiorespiratory Functions in Phase 1 Post CABG Patients
The aim of this study is to investigate effects of Anulom vilom pranayama/ Alternate nasal breathing (ANB) on cardio-respiratory parameters including vitals i.e.
- Trial name
- NCT04674865
- Testing
- Standardized Physical therapy protocol, Alternate nostrils breathing
- Where
- Pakistan
- Volunteers
- 22 people
- Sponsor
- Riphah International University
Heart; Surgery, Heart, Functional Disturbance as Result
FAPO-X: Assisted Digital Telemonitoring With Wearables in Patients After Cardiovascular Surgery
This study aims to develop a digitally assisted telemonitoring platform using the Samsung TM Galaxy Watch5 smartwatch, validating the applicability of the solution in patients with POAF (Postoperative Atrial Fibrillation), along…
- Trial name
- FAPO-X (NCT05966857)
- Testing
- Wearable: Smartwatch
- Where
- Brazil
- Volunteers
- 108 people
- Sponsor
- University of Sao Paulo
Myocardial Infarction, Mitral Regurgitation
Medical Versus Surgical Management of Moderate Mitral Regurgitation Following Percutaneous Coronary Intervention
The pilot prospective randomized trial is designed to determine the safety and feasibility of enrolling patients to surgically correct residual Mitral Regurgitation (MR) following Percutaneous Coronary Intervention (PCI) for…
- Trial name
- NCT01156441
- Testing
- surgical mitral valve repair w/ mitral valve annuloplasty
- Where
- United States
- Sponsor
- Southern Illinois University
Coronary Arterial Disease, Coronary Artery Bypass Grafting (CABG) Surgery
ESPB vs SPSIP for Postoperative Analgesia After CABG
This prospective, randomized, active-controlled, double-blind, parallel-group study compares the postoperative analgesic efficacy and safety of ultrasound-guided bilateral Erector Spinae Plane Block (ESPB) versus bilateral…
- Conditions
- Coronary Arterial Disease, Coronary Artery Bypass Grafting (CABG) Surgery, Postoperative Pain Management
- Trial name
- ESP-SPSIP-CABG (NCT07388745)
- Testing
- Ultrasound-guided Erector Spinae Plane Block (ESPB), Ultrasound-guided Serratus Posterior Superior Intercostal Plane Block (SPSIPB)
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people
- Sponsor
- Kutahya Health Sciences University
Acute Hypokalemia
Comparison of Enteral Versus Intravenous Potassium Supplementation
Null hypothesis: There is no difference in the efficacy of IVPR and EPR during an episode of hypokalemia. Alternate Hypothesis: There is a mean difference of 15% in Serum Potassium levels between the two groups.
- Trial name
- EIPS (NCT02015962)
- Testing
- Intravenous potassium chloride, Oral potassium chloride
- Where
- 3 sites in Pakistan
- Volunteers
- 40 people
- Sponsor
- Aga Khan University
Geriatric, General Anesthesia Induced Hypotension
What Causes Low Blood Pressure After Anesthesia in Older Adults Having Non-Heart Surgery ?
The purpose of this study is to identify risk factors contributing to post-induction hypotension in geriatric patients undergoing elective non-cardiac surgery under general anesthesia at Dr.
- Conditions
- Geriatric, General Anesthesia Induced Hypotension, Elective Surgery, Hypotension
- Trial name
- GERIHYPO (NCT07019805)
- Testing
- Standard General Anesthesia Induction Using Propofol, Fentanyl and Midazolam, Blood Pressure Continous Monitoring, syrnge pump for the anesthesia agent, and vasoconstrictor drug
- Where
- Indonesia
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia
Cardiothoracic Surgery
Pocket-size Ultrasound by Nurses in Cardiothoracic Post-operative Patients
The investigators aim to study the feasibility and reliability of pocket-size diagnostic ultrasound examinations performed by nurses of postoperative patients who have underwent cardiothoracic surgery in a cardiac unit.
- Trial name
- NCT01847859
- Testing
- Ultrasound examination by nurses
- Where
- Norway
- Volunteers
- 59 people
- Sponsor
- Helse Nord-Trøndelag HF
Electrolyte Imbalances, Acute Kidney Injury
Investigation of Fluid- and Electrolyte Balance in Post Cardiac-surgery Patients
Critically ill patients need intravenous fluid therapy in order to correct or prevent problems with their fluid and/or electrolyte status and for renal protection.
- Trial name
- Clinibil (NCT02914782)
- Testing
- Observational Study
- Where
- Austria
- Volunteers
- 176 people
- Sponsor
- Medical University of Graz
Pain, Acute, Pain, Chronic
Butyrate and Taurine for Chronic Postsurgical Pain in Adult Cardiac Surgical Patients
This study is a single-center, phase II, randomized, placebo-controlled, Bayesian-designed, double-blinded trial Goal and Questions: The primary goal is to evaluate if a combination of taurine and butyrate can reduce chronic…
- Conditions
- Pain, Acute, Pain, Chronic, Chronic Post Operative Pain
- Trial name
- NCT07144033
- Testing
- Butyrate and Taurine
- Where
- Hong Kong
- Volunteers
- 216 people
- Sponsor
- Chinese University of Hong Kong
Coronary Heart Disease, Mindfulness
Mindfulness-based Interventions on Psychophysiological Recovery and Physical Functioning After Coronary Heart Surgery
The purpose of this study is to explore the effect of mindfulness on the physical and mental recovery and physical function of patients after coronary heart surgery.
- Conditions
- Coronary Heart Disease, Mindfulness, Recovery, Psychological, Physical Functioning
- Trial name
- NCT06637969
- Testing
- mindfulness-based
- Where
- Taiwan
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Mackay Memorial Hospital
Kidney Failure, Acute
Preventing Acute Renal Failure After Cardiac Surgery in High Risk Patients Using Sodium Bicarbonate Therapy
The purpose of this study is to determine whether sodium bicarbonate is effective in reducing kidney injury that may occur during cardiac surgery.
- Trial name
- PARACHUTE (NCT00522756)
- Testing
- Sodium bicarbonate, Sodium chloride
- Where
- Canada
- Volunteers
- 200 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Cardiac Surgery
Optimal Timing of Coronary Artery Bypass Grafting in Hemodynamically Stable Patient After Myocardial Infarction and Definition of Poor Prognostic Factors. Pilot Study
Acute coronary syndromes (ACS) represent the leading cause of death in France. Their incidence is increasing due to population aging and to the persistence of cardiovascular risk factors.
- Trial name
- NCT03863158
- Testing
- No intervention
- Volunteers
- 476 people
- Sponsor
- Centre Hospitalier La Chartreuse
Hypoplastic Left Heart Syndrome
A Prospective Study of Patients With Hypoplastic Left Heart Syndrome (HLHS) Following Stage II Surgical Palliation
Hypoplastic left heart syndrome (HLHS) is a severe form of congenital heart disease that consists of multiple obstructions to flow through the left heart and aorta, as well as hypoplasia of the left ventricle.
- Trial name
- NCT01708863
- Where
- 3 sites in United States
- Volunteers
- 4 people
- Sponsor
- Timothy J Nelson, MD, PhD
Transposition of Great Vessels, Surgery
MRI Study After Arterial Switch Operation in Patients With Transposition of the Great Arteries
This study involves adolescents operated with arterial switch procedure for transposition of the great arteries during the neonatal period.
- Trial name
- NCT01916499
- Testing
- 3 tesla magnetic resonance imaging findings; coronary artery status, 3 tesla magnetic resonance imaging findings; ventricular function and morphology
- Where
- Norway
- Volunteers
- 70 people
- Sponsor
- Oslo University Hospital