Clinical trials: Patients After Cardiac Surgery
Postoperative; Dysfunction Following Cardiac Surgery, Postoperative; Dysfunction Following Lung Surgery
Comparison of Two Modes of Respiratory Physiotherapy in Cardio-thoracic Surgical Patients
Two forms of pre and postoperative physiotherapy are compared in three cohorts of patients undergoing cardio-thoracic surgery: Minor thoracic surgery (biopsy), major thoracic surgery (lobectomy etc, open or VATS) and cardiac…
- Trial name
- NCT02931617
- Testing
- Chest Physiotherapy, Post-therapy lung volume measurements
- Where
- Finland
- Volunteers
- 120 people
- Sponsor
- Tampere University Hospital
Recurrent Angina After Coronary Artery Bypass Graft, Graft Failure
Prior CABG Patients Evaluated for Saphenous VeIn grAft DysfUnction and Progression of Coronary arTery Disease
This is a multi-center, observational cohort study including patients with prior coronary artery bypass grafting (CABG) and ≥1 saphenous vein grafts (SVG) presenting with recurrent ischemic symptoms.
- Conditions
- Recurrent Angina After Coronary Artery Bypass Graft, Graft Failure, Coronary Artery Disease Progression
- Trial name
- VIADUCT (NCT04772768)
- Where
- Netherlands
- Volunteers
- 500 people
- Sponsor
- Amsterdam UMC, location VUmc
Heart; Surgery, Heart, Functional Disturbance as Result
The Effect of 10 Repetitions of Deep Breathing Exercises
The goal of this clinical trial is to learn and assess the effect of 10 repetitions of deep breathing exercises every 3 hours compared to 3 repetitions of deep breathing exercises on the sleep quality of patients after heart…
- Trial name
- NCT06435715
- Testing
- 10 Repetitions of Deep Breathing Exercise, 3 Repetitions of Deep Breathing Exercise
- Where
- Indonesia
- Volunteers
- 50 people
- Sponsor
- Universitas Indonesia
Delirium Symptoms
Role of REM Sleep Alterations in Post Operative Delirium After Cardiac Surgery
Acute confusional states known as delirium frequently occur in Intensive Care Units (ICU), mostly after cardiac surgery, leading to serious consequences.
- Trial name
- NCT02801318
- Testing
- Polysomnography
- Volunteers
- 60 people
- Sponsor
- Poitiers University Hospital
Pulmonary Atelectasis
Interest of Positive Expiratory Pressure (PEP) Delivery by EzPAP® After Cardiac Surgery in the Management of Postoperative Atelectasis
Pulmonary atelectasis is a frequent respiratory postoperative complication in cardiac surgery. Classically, the treatment of these patients is based on manual chest physiotherapy.
- Trial name
- PEPKIN (NCT02262182)
- Testing
- KP group, KM group
- Where
- France
- Volunteers
- 80 people
- Sponsor
- Nantes University Hospital
Anesthesia, Neurocognitive Disorders
Neurocognitive Disorders After Major Surgery in Elderly
The objective of the study is to investigate, in patients aged 70 years and over undergoing major non-cardiac surgery, the effect of electroencephalic (EEG)-guided anesthesia on postoperative neurocognitive disorders when…
- Trial name
- POEGEA (NCT04825847)
- Testing
- BIS monitor, Control group
- Where
- Canada
- Volunteers
- 314 people
- Sponsor
- Ciusss de L'Est de l'Île de Montréal
Carcinoma, Non-Small-Cell Lung, Pain, Postoperative
Why in Hospital After VATS Lobectomy
The study aims to identify specific or potential reasons that prolong the length of hospital stay after video-assisted thoracoscopic surgery lobectomy.
- Conditions
- Carcinoma, Non-Small-Cell Lung, Pain, Postoperative, Postoperative Nausea and Vomiting, Infection
- Trial name
- NCT04294108
- Testing
- Prolong in-hospital stay
- Where
- Denmark
- Volunteers
- 160 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Stress Hyperglycemia
Metabolic Phenotyping During Stress Hyperglycemia in Cardiac Surgery Patients
This study is a prospective randomized study to examine the effects of exposure to dulaglutide on the prevention of stress-hyperglycemia and the metabolic inflammatory response in the perioperative period.
- Trial name
- NCT03743025
- Testing
- Dulaglutide Injection, Saline Injection
- Where
- 3 sites in United States
- Volunteers
- 28 people
- Sponsor
- Emory University
Coronary Artery Bypass Graft Surgery
Effects of Massage Therapy on Sleep After Heart Surgery
The purpose of this study is to evaluate the effects of Massage Therapy for improving the quality of sleep in patients on postoperative period of coronary artery bypass graft surgery (CABG).
- Trial name
- MT and CABG (NCT01095419)
- Testing
- Massage Therapy, Control
- Where
- Brazil
- Volunteers
- 40 people
- Sponsor
- University of Sao Paulo
C.Surgical Procedure; Cardiac, Acute Kidney Injury
Portal Flow Pulsatility as a Risk Factor for Acute Kidney Injury After Cardiac Surgery
The purpose of this study is to evaluate the possible association between portal vein flow pulsatility and acute kidney injury after cardiac surgery.
- Conditions
- C.Surgical Procedure; Cardiac, Acute Kidney Injury, Postoperative Complications, Right-Sided Heart Failure
- Trial name
- PP-AKI (NCT02831907)
- Testing
- Cardiac surgery
- Where
- Canada
- Volunteers
- 146 people
- Sponsor
- Montreal Heart Institute
Post-cardiac Surgery, Rehabilitation
Aerobic Reconditioning After Cardiac Surgery Using a Predictive Exercise Model
Brief Summary After heart surgery, aerobic exercise is essential for recovery. Traditional exercise planning uses a cardiopulmonary exercise test (CPET), which may be unavailable early after surgery.
- Trial name
- NCT07440407
- Testing
- Equation-Based Aerobic Exercise Prescription, Symptoms-Based Aerobic Exercise Prescription
- Where
- Italy
- Volunteers
- 118 people
- Sponsor
- Istituti Clinici Scientifici Maugeri SpA
Coronary (Artery); Disease
Follow-up of Patients With Multivessel Coronary Artery Disease After CABG
The FAMOUS Trial is a single-center, prospective, randomized study aimed to compare three different strategies (clinical, anatomical, or functional) in preventing MACE after CABG.
- Trial name
- FAMOUS (NCT03040700)
- Testing
- Myocardial Perfusion Scan, Coronary CTA
- Where
- Brazil
- Volunteers
- 600 people
- Sponsor
- Ministry of Health, Brazil
Patients Undergoing Valvular Heart Surgery
A Prediction Model for 1-year Mortality After Valvular Heart Surgery
The investigators aimed to develop a predictive model for mortality incorporating nutritional, inflammatory, and perioperative factors in patients undergoing valvular heart surgery.
- Trial name
- NCT05833256
- Where
- South Korea
- Volunteers
- 2,046 people
- Sponsor
- Yonsei University
Hemodynamic Instability
Hemodynamic Effect of Dexmedetomidine Alone With Dexmedetomidine Plus Ketamine Combination in CABG
In post cardiac surgery, many cardiovascular and other complications may occur that lead to increase in mortality and hospital stays. Meticulous perioperative management is important to avoid these adverse events.
- Trial name
- NCT05218161
- Testing
- Dexmedetomidine alone
- Where
- Pakistan
- Volunteers
- 40 people
- Sponsor
- Chaudhry Pervaiz Elahi Institute of Cardiology
Aortic Valve Insufficiency, Aortic Valve Stenosis
Study of Administration Of Antithrombin in Patients With Low Plasmatic Levels of Antithrombin After Cardiac Surgery
General and specific objectives of the search: evaluate the effects of the administration of Antithrombin III (ATIII) on the activation of the coagulation system and of the fibrinolysis, platelet function, inflammatory response…
- Conditions
- Aortic Valve Insufficiency, Aortic Valve Stenosis, Mitral Valve Insufficiency, Mitral Valve Stenosis
- Trial name
- ATIII (NCT01201070)
- Testing
- antithrombin III
- Where
- Italy
- Volunteers
- 90 people
- Sponsor
- University of Bari
Frailty Syndrome, Ischaemic Heart Disease
Cardiac Rehabilitation and Additional Physical Training in Elderly Patients After Acute Coronary Syndrome
The aim of this study is to evaluate functional and physical capacity, health-related quality of life and associations with frailty in older patients after ischemic heart disease and interventional treatment with an…
- Trial name
- NCT04768283
- Testing
- Additional balance and resistance training - 1, Additional balance and resistance training - 2
- Where
- Lithuania
- Volunteers
- 100 people
- Sponsor
- Lithuanian University of Health Sciences
Myocardial Injury, Thoracic Diseases
Effects of Ciprofol on Myocardial Injury After Non-cardiac Surgery in Video-Assisted Thoracoscopic Surgery
Myocardial injury after noncardiac surgery (MINS) refers to postoperative elevation of cardiac troponin (cTn) levels caused by underlying ischemic mechanisms (i.e., coronary artery supply-demand imbalance or atherosclerotic…
- Conditions
- Myocardial Injury, Thoracic Diseases, Thoracoscopic Surgery
- Trial name
- CP-MINS (NCT07028593)
- Testing
- Propofol, ciprofol
- Where
- China
- Volunteers
- 1,058 people
- Sponsor
- Tongji Hospital
Respiration Disorders
Impact of Positive End Maximum Voluntary Ventilation and Dyspnea Index in Patients After Valvular Heart Surgery
Pulmonary mechanics are further disturbed after cardiothoracic surgery that manifests like restrictive pathology, which may persist for weeks to months postoperatively.
- Trial name
- NCT05267067
- Testing
- respiratory exercises
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Cairo University
Single Ventricle Heart Disease After Fontan Surgery
Study of Effects of Sildenafil on Patients With Fontan Heart Circulation
The study will investigate the cardiovascular effects of sildenafil on patients with Fontan circulation. Recent studies suggest that sildenafil may improve exercise in patients with Fontan circulation.
- Trial name
- NCT01815502
- Testing
- Cardiac catheterization
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Medical University of South Carolina
Inflammatory Response, Extracorporeal Circulation; Complications
Role of Type 2 Diabetes in Potentiating the Inflammatory Response Post Extracorporeal Circulation After Cardiac Surgery
Adult cardiac surgery ensures the surgical treatment of valvular and coronary pathologies and of heart failure with the placement of ventricular assistance.
- Conditions
- Inflammatory Response, Extracorporeal Circulation; Complications, Cardiac Surgery, Type 2 Diabetes
- Trial name
- DT2CEC (NCT04432337)
- Testing
- The role of the activation of the NLRP3 inflammasome after cardiac surgery
- Where
- Martinique
- Sponsor
- University Hospital Center of Martinique