Clinical trials: Patients After Cardiac Surgery
Sarcopenia, Frailty
Impact of Hand Grip Strength on Length of Hospital Stay After Cardiac Surgery Among Elderly Patients
Hand grip strength has been shown to be a predictor of adverse cardiovascular outcomes in the elderly population. This study aims to investigate whether measurement of hand grip strength could be used as a predictor of prolonged…
- Trial name
- NCT05546671
- Testing
- Hand grip strength measurement
- Where
- Turkey (Türkiye)
- Volunteers
- 240 people
- Sponsor
- Kartal Kosuyolu High Speciality Training and Research Hospital
Hip Fracture, Myocardial Ischemia
Pilot Study of Atorvastatin for Orthopedic Surgery Patients
Up to 35% of hip fracture patients have been shown to experience heart injury after surgery, and as many as 10% have a heart attack or die in the three months after surgery.
- Conditions
- Hip Fracture, Myocardial Ischemia, Inflammation
- Trial name
- POST-OP Pilot (NCT02197065)
- Testing
- Atorvastatin
- Where
- 2 sites in United States
- Volunteers
- 20 people
- Sponsor
- Hospital for Special Surgery, New York
Neutrophil Lymphocyte Ratio, Serum Createnine
Does Preconditioning Affects Other Organs in Patients Undergoing Open Heart Surgery ?
An association between white blood cell count (WBC), neutrophil-lymphocyte ratio , and inflammatory process is well known . Ischemic preconditioning reduces the inflammation
- Conditions
- Neutrophil Lymphocyte Ratio, Serum Createnine, Mechanical Ventilation
- Trial name
- NCT03097692
- Testing
- ischemic preconditioning, Pharmacologic preconditionig
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Assiut University
C.Surgical Procedure; Cardiac, Acute Kidney Injury
Portal Flow Pulsatility as a Risk Factor for Acute Kidney Injury After Cardiac Surgery
The purpose of this study is to evaluate the possible association between portal vein flow pulsatility and acute kidney injury after cardiac surgery.
- Conditions
- C.Surgical Procedure; Cardiac, Acute Kidney Injury, Postoperative Complications, Right-Sided Heart Failure
- Trial name
- PP-AKI (NCT02831907)
- Testing
- Cardiac surgery
- Where
- Canada
- Volunteers
- 146 people
- Sponsor
- Montreal Heart Institute
Other Functional Disturbances Following Cardiac Surgery, Postoperative Hemorrhage
A Gray Zone Approach of Rotational Thromboelastometry for Predicting Postoperative Bleeding in Cardiac Surgical Patients
Rotational thromboelastometry (ROTEM) is reliable point of care management of coagulation disorder undergoing surgery. Recently, there are some reports about prediction of perioperative bleeding using ROTEM.
- Conditions
- Other Functional Disturbances Following Cardiac Surgery, Postoperative Hemorrhage, Coagulation Defect; Bleeding
- Trial name
- NCT01889732
- Testing
- ROTEM
- Where
- South Korea
- Volunteers
- 200 people
- Sponsor
- Samsung Medical Center
Post-cardiac Surgery
Clinical Pilates (CP) Exercises and Kinesiophobia in CABG
To determine Effect of Clinical Pilates (CP) exercises on kinesiophobia and post-operative cardiopulmonary parameters in CABG patients.
- Trial name
- NCT06426914
- Testing
- Clinical Pilates, Cardiac Rehabilitation
- Where
- Pakistan
- Volunteers
- 36 people
- Sponsor
- Riphah International University
Cardiac Surgery, Median Sternotomy
Early Rehabilitation in Patients Following Major Cardiac Surgery: Changes in Functional Capacity and Energy Efficiency in Walking and ADLs.
The main objective of this clinical trial is to evaluate exercise capacity before and after an inpatient or outpatient rehabilitation program in patients following major cardiac surgery.
- Trial name
- K5-POSTCCH (NCT07843316)
- Testing
- Use of COSMED K5, a portable metabolic system that allows real-time measurement of respiratory gas exchange, ventilation, and energy expenditure during physical activities.
- Where
- 3 sites in Italy
- Volunteers
- 60 people
- Sponsor
- Istituti Clinici Scientifici Maugeri SpA
Hypotension on Induction, Frailty
EASIX Score and Post-Induction Hypotension in Frail Patients Undergoing Non-Cardiac Surgery
Post-induction hypotension (PIH) is a common and clinically significant hemodynamic complication following general anesthesia induction.
- Conditions
- Hypotension on Induction, Frailty, Anesthesia, General
- Trial name
- PIXEL (NCT07642765)
- Testing
- EASIX Score Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 160 people
- Sponsor
- Konya City Hospital
Valvular Diseases
Effectiveness of Remote Cardiac Rehab After Surgery for Acquired Heart Valve Disease
The goal of this clinical trial is to learn if home-based cardiac rehabilitation using remote monitoring devices improves exercise capacity in patients after surgery for acquired heart valve diseases.
- Trial name
- NCT06984172
- Testing
- Remote cardiac rehabilitation, Facility-based cardiac rehabilitation
- Where
- Vietnam
- Volunteers
- 44 people
- Sponsor
- Hanoi Medical University
Cardiopulmonary Bypass, Cardiac Surgery
Ulinastatin Improves Postoperative Oxygenation After Cardiopulmonary Bypass
Retrospective study determine whether ulinastatin enhances postoperative pulmonary oxygenation after cardiopulmonary bypass (CPB).
- Trial name
- NCT03154814
- Testing
- ulinastatin, control
- Where
- 2 sites in South Korea
- Volunteers
- 80 people
- Sponsor
- Konkuk University Medical Center
Cardiac Surgery
RECOVER I Impella RECOVER LP/LD 5.0 Support System Safety and Feasibility Study
To demonstrate that that the device is safe and potentially efficacious for use as a left ventricular cardiac assist device for postcardiotomy patients who require hemodynamic support post weaning from cardiopulmonary bypass.
- Trial name
- RECOVER I (NCT00596726)
- Testing
- IMPELLA LP/LD 5.0
- Where
- 7 sites in United States
- Volunteers
- 17 people
- Sponsor
- Abiomed Inc.
Hemodynamic Instability, Postoperative Complications
Fluid Responsiveness: SVV vs esSVV in Mechanically Ventilated and Spontaneously Breathing Patients
Postoperative period after off-pump coronary artery bypass grafting (OPCAB) can be a challenging area for emerging methods for less-invasive continuous hemodynamic monitoring.
- Trial name
- NCT04786652
- Testing
- estimated stroke volume variation (esSVV, Nihon Kohden, Japan), Assessment of fluid responsiveness in mechanically ventilated patients after OPCAB, Assessment of fluid responsiveness in spontaneously breathing patients at 18 hrs of the postoperative period
- Where
- Russia
- Volunteers
- 32 people
- Sponsor
- Northern State Medical University
CT Coronary Angiography, Arterial Switch Operation
CT Coronary Angiography After Arterial Switch Operation
The purpose of this study is to find a non-invasive alternative (with using ECG gated 64-slice CT angiography) to invasive coronary angiography for detecting coronary lesions in patients who had undergone arterial switch…
- Trial name
- SCANTGV (NCT01153776)
- Testing
- 64-slice CT angiography
- Where
- France
- Volunteers
- 42 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Older Patients, Surgery
Dexmedetomidine-esketamine and tDCS for Prevention of Neurocognitive Complications After Surgery
Neurocognitive complications, mainly delirium and neurocognitive disorders, are common cerebral complications in older patients after surgery and associated with worse outcomes.
- Conditions
- Older Patients, Surgery, Dexmedetomidine, Esketamine
- Trial name
- NCT07576517
- Testing
- Dex-Esk, Active tDCS
- Where
- 6 sites in China
- Volunteers
- 1,996 people, healthy volunteers welcome
- Sponsor
- Peking University First Hospital
Shock
Renin as a Biomarker of Haemodynamic Normalisation
Study design Observational, single centre, prospective cohort study Planned sample size 100 participants Inclusion criteria The study will evaluate a cohort of participants meeting the following inclusion criteria: 1.
- Trial name
- NCT04303455
- Testing
- blood sampling
- Where
- Australia
- Volunteers
- 104 people
- Sponsor
- South West Sydney Local Health District
Heart Disease, Coronary Artery Disease
Bleeding Prediction in Patients Following Cardiac Surgery Using Whole Blood Aggregometry and Thromboelastometry
Use of whole blood impedance aggregometry and rotational thromboelastometry can reveal useful data about platelet function and viscoelastic properties of blood clot in patients undergoing cardiac surgery.
- Conditions
- Heart Disease, Coronary Artery Disease, Aortic Valve Disease, Mitral Valve Disease
- Trial name
- NCT01281397
- Where
- Croatia
- Volunteers
- 148 people
- Sponsor
- University of Zagreb
Off Pump Coronary Artery Bypass Surgery
Getinge's Beating Heart Product Family Post-Market Clinical Follow-up (PMCF) Study
This observational study aims to collect data on the performance and safety of Getinge's Beating Heart products used during open-heart coronary artery bypass graft surgery.
- Trial name
- NCT07286890
- Testing
- Vacuum Stabilizer System, Vacuum Positioner System, Blower/Mister
- Where
- 7 sites in United States, Germany and 1 more
- Volunteers
- 200 people
- Sponsor
- Maquet Cardiovascular
Atrial Fibrillation New Onset, Hemorrhage
Randomized Double Blind Control Trial on Effects of Ranolazine on New Onset Atrial Fibrillation
The aim of this study is to evaluate the prophylactic effects of Ranolazine on new onset atrial fibrillation in post-operative coronary artery bypass graft and valve surgery patient population at Staten Island University hospital.
- Conditions
- Atrial Fibrillation New Onset, Hemorrhage, Prolonged QTc Interval, Ventricular Tachycardia
- Trial name
- NCT01590979
- Testing
- Ranolazine
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- Northwell Health
Coronary Artery Disease
Effect of Clopidogrel (Plavix) on Postoperative Bleeding in Patients Undergoing Coronary Artery Bypass Surgery.
Running title: Effect of Clopidogrel on Postoperative Bleeding in Patients undergoing Coronary Artery Bypass Surgery Title: Clopidogrel and bleeding in patients undergoing coronary artery bypass grafting.
- Trial name
- NCT00724880
- Testing
- Clopidogrel
- Volunteers
- 135 people
- Sponsor
- Catharina Ziekenhuis Eindhoven
Postoperative Pain, Cardiac Surgery
Comparison of Paravertebral Block and Deep Parasternal Intercostal Plane Block in Cardiac Surgery
Median sternotomy is commonly used in cardiac surgery and is often associated with significant postoperative pain. Poor pain control after sternotomy may increase opioid use, delay mobilization, prolong extubation time, and…
- Conditions
- Postoperative Pain, Cardiac Surgery, Postoperative Pain After Cardiac Surgery Via Median Sternotomy
- Trial name
- SPARE-CABG (NCT07498946)
- Testing
- Thoracic paravertebral block (TPVB), Bilateral Deep Parasternal Intercostal Plane Block
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Gaziantep City Hospital