Clinical trials: Patients After Cardiac Surgery
Coronary Artery Bypass Graft Surgery, Mace
Discharge Planning Program for Post CABG Patients
The current study is utilizing a nurse led discharge program based on the Re-Engineered Discharge program (Project-RED) ( Agency of Healthcare Research and Quality [AHRQ], 2013) which is a package of services designed to minimize…
- Conditions
- Coronary Artery Bypass Graft Surgery, Mace, 30 Day Mortality
- Trial name
- NCT04527822
- Testing
- Nurse led discharge planning program
- Where
- Jordan
- Volunteers
- 174 people
- Sponsor
- University of Jordan
Disruption or Dehiscence of Closure of Sternum or Sternotomy
Treatment With PTH After Sternotomy in Cardiac Surgery Patients
The aims of this study is to compare healing time and quality of newly formed bone in cardiac surgery patients treated with PTH post-surgically and a control group treated with saline.
- Trial name
- PAATH (NCT01466829)
- Testing
- Parathyroid hormone
- Where
- Denmark
- Volunteers
- 20 people
- Sponsor
- University of Aarhus
Post Induction Hypotension
Comparing the Hemodynamic Effects of Volume Loading vs Non-loading During Induction of Anesthesia in Fluid Responder Patients With Coronary Artery Disease Undergoing Elective Coronary Artery Bypass Graft Surgery: a Randomized Controlled Study.
All preoperative cardiac medications will be continued till the morning of the surgery, except angiotensin converting enzyme inhibitors.
- Trial name
- NCT05462847
- Testing
- Ringer acetate
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Kasr El Aini Hospital
Cardiac Surgery
Optimal Timing of Coronary Artery Bypass Grafting in Hemodynamically Stable Patient After Myocardial Infarction and Definition of Poor Prognostic Factors. Pilot Study
Acute coronary syndromes (ACS) represent the leading cause of death in France. Their incidence is increasing due to population aging and to the persistence of cardiovascular risk factors.
- Trial name
- NCT03863158
- Testing
- No intervention
- Volunteers
- 476 people
- Sponsor
- Centre Hospitalier La Chartreuse
Elderly Patients, Non-cardiac Surgery
Effects of Limb Remote Ischemic Preconditioning for Prevention of Delirium in Elderly Patients After Non-cardiac Surgery
To investigate whether limb remote ischemic preconditioning (LRIP) could safely decrease the incidence of delirium in elderly patients after non-cardiac surgery.
- Trial name
- LRIP-D (NCT03028389)
- Testing
- limb remote ischemic preconditioning(LRIP)
- Volunteers
- 611 people
- Sponsor
- Nanfang Hospital, Southern Medical University
Kidney Tubular Necrosis, Acute
Allogeneic Multipotent Stromal Cell Treatment for Acute Kidney Injury Following Cardiac Surgery
The purpose of this trial is to determine if the administration of allogeneic MSCs at defined doses is safe in patients who are at high risk of developing significant Acute Kidney Injury (AKI) after undergoing on-pump cardiac…
- Trial name
- NCT00733876
- Testing
- Multipotent Stromal Cells, Administration of MSC
- Where
- 2 sites in United States
- Volunteers
- 15 people
- Sponsor
- AlloCure Inc.
Post Cardiac Surgery
Minimal Volume for Fluid Challenge in Post-operative Patients
This study evaluate the effect of different doses of crystalloids on the changes on cardiac output (CO) and on the proportion of responders and non-responders and aims to determine the minimal volume required to increase the mean…
- Trial name
- NCT02569008
- Testing
- Fluid challenge with Compound Sodium Lactate
- Where
- United Kingdom
- Volunteers
- 80 people
- Sponsor
- St George's, University of London
Atrial Fibrillation, Atrial Flutter
Colchicine For The Prevention Of Perioperative Atrial Fibrillation In Patients Undergoing Thoracic Surgery (COP-AF)
The prevention of perioperative atrial fibrillation (AF) and myocardial injury after non-cardiac surgery (MINS) has the potential to reduce mortality, stroke, and hospital stays in patients undergoing major thoracic surgery.
- Conditions
- Atrial Fibrillation, Atrial Flutter, Myocardial Injury After Non-Cardiac Surgery
- Trial name
- COP-AF (NCT03310125)
- Testing
- Active Colchicine
- Where
- 46 sites in United States, Austria and 9 more
- Volunteers
- 3,209 people
- Sponsor
- Population Health Research Institute
Cardiac Failure, Ventricular Dysfunction
Safety and Efficacy of the Gastric Reactance (XL) in Patients Post-operated of Elective Cardiac Surgery
Evaluate the safety and effectiveness of the XL trend measured by Florence (Critical Perfusion Inc, Palo Alto, California) in the prediction of morbimortality of Mexican patients post-operated of elective cardiovascular surgery.
- Conditions
- Cardiac Failure, Ventricular Dysfunction, Valvular Heart Disease
- Trial name
- NCT03799133
- Testing
- Florence device
- Where
- Mexico
- Volunteers
- 38 people
- Sponsor
- Critical Perfusion Inc.
Sleep Disorder, Sleep Disturbance
TRANslating Sleep Health Into QUaLity of Recovery (TRANQUiL) Study
This is a novel observational study with the overarching aim of evaluating the association between poor sleep health and poor quality of recovery in a surgical setting.
- Trial name
- TRANQUiL (NCT04398082)
- Where
- 2 sites in Canada
- Volunteers
- 174 people
- Sponsor
- Women's College Hospital
Development, Child, Adherence, Patient
BabySparks Developmental Application Pilot Study
A single site, cross-sectional, pilot study of a mHealth application. Primary Objective This purpose of this pilot study is to evaluate mHealth adherence to a developmental application, Babysparks©, by parents of infants with…
- Conditions
- Development, Child, Adherence, Patient, Congenital Heart Disease
- Trial name
- NCT03867903
- Testing
- Babysparks Application, pre and post-test Redcap Survey
- Where
- United States
- Volunteers
- 66 people
- Sponsor
- Children's Mercy Hospital Kansas City
Pulmonary Hypertension
Sildenafil for Post-capillary Pulmonary Hypertension in Patients Undergoing Cardiac Surgery
Pulmonary hypertension increases the perioperative risk in patients undergoing cardiac surgery for valvular heart diseases, especially in patients with a long life mitral valve disease.
- Trial name
- SiPaHCS (NCT01481350)
- Testing
- sildenafil
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- University of Turin, Italy
Acute Coronary Syndrome, Cardiogenic Shock
Outcome of Patients Treated With IABP
Intra-Aortic Balloon Pumps (IABP) is a widely used and effective left ventricular adjuvant therapy. IABP is an inflatable device placed in the aorta that inflates with diastole and deflates with systole.
- Conditions
- Acute Coronary Syndrome, Cardiogenic Shock, Coronary Artery Disease, Heart Failure
- Trial name
- NCT04405856
- Testing
- Intra Aortic Balloon Pump
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- Nanjing Medical University
Hypertrophic Obstructive Cardiomyopathy \(HOCM\), Neurologic Evaluation
Neurologic Evaluation of Patients After Transapical Beating-Heart Septal Myectomy
The goal of this prospective cohort study is to evaluate the neurologic changes in patients that received transapical beating-heart septal myectomy.
- Conditions
- Hypertrophic Obstructive Cardiomyopathy \(HOCM\), Neurologic Evaluation, Magnetic Resonance Imaging \(MRI\), Transapical Beating-Heart Septal Myectomy
- Trial name
- NCT06078410
- Testing
- Cardiac surgery
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Xiang Wei
Kidney Injury, Acute
Perioperative Use of NAC to Prevent AKI in Patients With Pre-existing Moderate Renal Insufficiency Following Cardiac Surgery
Acute kidney injury (AKI) or renal impairment is an established complication of cardiac surgery occurring with an incidence up to 30%, To date, no agent has conferred renal protection.
- Trial name
- NCT05555511
- Testing
- Control Group
- Where
- Egypt
- Volunteers
- 46 people
- Sponsor
- Ain Shams University
Breast Cancer, Myocardial Injury After Noncardiac Surgery (MINS)
Impact of Propranolol Strategies on Myocardial Injury After Breast Cancer Surgery
This study aims to evaluate the impact of using propranolol, a non-selective beta-blocker, on preventing myocardial injury after non-cardiac surgery (MINS) in breast cancer patients who also have hypertension or angina.
- Trial name
- B-BIT (NCT07583134)
- Testing
- propranolol, Usual Care
- Where
- South Korea
- Volunteers
- 100 people
- Sponsor
- Chang-Ik Yoon
Peri-operative Myocardial Infarction, Non-ST Elevation Myocardial Infarction
Study of Coronary Plaque Rupture in Heart Attack Following Surgery Using Optical Coherence Tomography (OCT)
Background It is commonly believed that a heart attack is caused by rupture of a plaque in the wall of the coronary artery, resulting in blood clots which impede blood flow.
- Trial name
- OPTIMUS (NCT01555177)
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- Victar Hsieh
Preoperative KIDNEY FAILURE, CHRONIC, Postoperative KIDNEY FAILURE, ACUTE
NGAL Predictive Value of Acute Kidney Failure After Cardiac Surgery in Patients With Preoperative Chronic Kidney Failure
Primary endpoint: To evaluate predictive value of plasmatic levels of Neutrophil Gelatinase Associated Lipocalin (NGAL) to reveal acute kidney failure after cardiac surgery in patients with preoperative chronic kidney failure…
- Conditions
- Preoperative KIDNEY FAILURE, CHRONIC, Postoperative KIDNEY FAILURE, ACUTE, Cardiac Surgical Procedures
- Trial name
- NGAL-CKF (NCT01227122)
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Hopital Jean Minjoz
Gradient Between Radial and Central Aortic Pressure After Cardiopulmonary Bypass
Evaluation of Aortic-Radial Blood Pressure Gradient in Pediatric Patients Undergoing Cardiac Surgery With Cardiopulmonary Bypass
Invasive blood pressure monitoring is essential during heart surgery. Usually, doctors measure blood pressure using a small tube (a catheter) placed in an artery, typically in the wrist or arm.
- Trial name
- GARP (NCT07857811)
- Testing
- Placement of a pressure transducer at the accessory port of the CPB arterial cannula
- Where
- 2 sites in Chile
- Volunteers
- 100 people
- Sponsor
- Pontificia Universidad Catolica de Chile
Preemptive Therapy of Patients At Risk for Acute Kidney Injury Following Cardiac Surgery
Phase 1B/2 Clinical Trial Assessing the Safety, Tolerability and Preliminary Efficacy of the Intravenous Administration of Allogeneic Placental Mesenchymal Cells for the Preemptive Treatment of Patients At Risk for Acute Kidney Injury Following Cardiac Surgery
This clinical trial is designed to evaluate KELI-101 versus placebo for the prevention of acute kidney disease leading to chronic kidney disease in subjects at high risk for acute kidney injury following cardiac surgery.
- Trial name
- MesAKI (NCT06678399)
- Testing
- KELI-101
- Volunteers
- 91 people
- Sponsor
- Kelifarma