Clinical trials: Patients After Cardiac Surgery
Critical Illness, Intensive Care
Registration Enabling Study of the Safety and Efficacy of the Use of the Navigator Circulatory Management System
A multicentre, open, RCT to assess the safety and efficacy of the Navigator Guided Circulatory Management System versus conventional care in post-operative cardiac surgery patients.
- Trial name
- NAV-1 (NCT00468247)
- Testing
- Navigator, Conventional care
- Where
- 7 sites in Australia
- Volunteers
- 112 people
- Sponsor
- Applied Physiology Pty Ltd
A Total of 234 Patients With Acute Coronary Syndrome Who Will Undergo OPCAB.
Impact of High-dose Pretreatment of Rosuvastatin in Patients With Acute Coronary Syndrome Following Off-pump Coronary Artery Bypass: Results From the HIROP-ACS (HIgh-dose Pretreatment of Rosuvastatin During Off-Pump Coronary Bypass in Acute Coronary Syndrome) Study
Periprocedural treatment with high-dose statins is known to have cardioprotective and pleiotropic effects, such as anti-thrombotic and anti-inflammatory actions.
- Trial name
- NCT01971606
- Testing
- Rosuvastatin
- Where
- South Korea
- Volunteers
- 234 people
- Sponsor
- Yonsei University
Digestive System Disease, Urologic Diseases
Low-dose Droperidol for Prevention of Postoperative Delirium in Elderly Patients After Non-cardiac Surgery
The aim of this multicenter, prospective, randomized, double-blind and large sample study is to explore the preventive effect of low-dose droperidol on POD in elderly patients after non-cardiac surgery, providing new approach for…
- Conditions
- Digestive System Disease, Urologic Diseases, Gynecological Disease, Orthopedic Surgery
- Trial name
- NCT05401058
- Testing
- Droperidol Injection, Saline
- Where
- 9 sites in China
- Volunteers
- 797 people
- Sponsor
- RenJi Hospital
Delirium
Cerebral Blood Flow During CPB During Cardiac Surgery and the Presence of Post op Delirium
Cardiac surgery is associated with multiple events and issues that increase risk for adverse postoperative neurological outcomes including postoperative cognitive dysfunction.
- Trial name
- NCT02084394
- Where
- United States
- Volunteers
- 110 people
- Sponsor
- Johns Hopkins University
Remote Monitoring
Remote Monitoring to Improve Physician Monitoring, Patient Satisfaction, and Predict Readmissions Following Surgery
This study is designed to determine the perceived value of continuous remote monitoring to surgeons and surgical patients at Mayo Clinic in Rochester, MN, and determine whether algorithms can be generated to predict risk of…
- Trial name
- NCT03800329
- Testing
- Snap40 Monitor, No Monitor
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Mayo Clinic
Postoperative Complications, Surgical Wound Infection
Acupuncture and Post-Surgical Wound Healing
The purpose of this study is to determine if acupuncture improves wound healing. Since we, the investigators at the University of California, San Francisco (UCSF), know that how much oxygen is delivered to tissue is the best…
- Conditions
- Postoperative Complications, Surgical Wound Infection, Surgical Wound Dehiscence
- Trial name
- NCT00260494
- Testing
- acupuncture
- Where
- United States
- Volunteers
- 65 people
- Sponsor
- University of California, San Francisco
Sarcopenia, Cardiac Surgery
Sarcopenia and Training Outcomes in Post-cardiac Surgery Patients
The goal of this observational study is to assess the prevalence of sarcopenia and see whether the current care is sufficient to improve sarcopenia outcomes in patients after cardiac surgery.
- Trial name
- STRONG (NCT07908472)
- Testing
- No intervention (observational study)
- Where
- Belgium
- Volunteers
- 300 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Hemodynamics, Patient Monitoring
Assessment of Fluid Responsiveness in Patients After Cardiac Surgery
To overcome the limited accuracy of functional hemodynamic parameters such as stroke volume and pulse pressure variation (SVV and PPV) during spontaneous breathing, a Passive Leg Raising (PLR) manoeuvre has been suggested as a…
- Trial name
- POP (NCT02571465)
- Testing
- Passive leg raising test and fluid challenge
- Where
- Switzerland
- Volunteers
- 40 people
- Sponsor
- Triemli Hospital
Respiratory Failure, Shock
Comparing Post Cardiac Surgery Outcomes in ESRD Patient's With Early Dialysis Versus Standard Care
End-stage renal disease (ESRD) is an important risk factor for coronary and valvular cardiac disease leading to cardiac surgery.
- Conditions
- Respiratory Failure, Shock, Coagulopathy
- Trial name
- NCT04705701
- Testing
- Hemodialysis
- Sponsor
- Northwell Health
Coronary Artery Bypass Grafting, Post Coronary Artery Bypass Grafting
Effect of Early Low Resisted Exercise With Blood Flow Restriction on Pulmonary Function in Post Cardiac Surgery Patient
After cardiac surgery Patients present a loss of exercise capacity, muscle mass, and quality of life Cardiopulmonary rehabilitation aims to reduce the loss of muscle strength, size and increase cardiopulmonary function so that…
- Trial name
- NCT06956911
- Testing
- traditional cardiac rehabilitation with early low resisted exercise with blood flow restriction, traditional cardiac rehabilitation
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Cairo University
Pain After Surgery, Pain and Anxiety
The Effect of Virtual Reality Headsets on Pain, Anxiety, Patient Satisfaction, and Physiological Parameters in Patients Undergoing Open-Heart Surgery
This randomized controlled trial aims to investigate the effects of virtual reality headset use on pain, anxiety, patient satisfaction, and physiological parameters in patients undergoing open-heart surgery.
- Conditions
- Pain After Surgery, Pain and Anxiety, Anxiety After Surgery, Anxiety
- Trial name
- NCT07843511
- Testing
- Virtual Reality Glasses
- Where
- Turkey (Türkiye)
- Volunteers
- 44 people
- Sponsor
- Dokuz Eylul University
Heart Block, Risk Factor
New-onset Heart Blocks After Noncardiac Surgery: a Retrospective Study of More Than 280,000 Patients
This study aimed to investigate new-onset heart blocks after noncardiac surgery, identify risk factors, and develop a prediction model.
- Trial name
- NCT06119009
- Testing
- non interventions
- Volunteers
- 281,497 people
- Sponsor
- Chinese PLA General Hospital
Lung Cancer, Atrial Fibrillation
PREvention of Atrial Fibrillation in patientS Undergoing thorAcic surGEry for Lung Cancer
The aim of this study is to assess whether prophylactic treatment with metoprolol or losartan is able to reduce the incidence of atrial fibrillation (AF) in patients undergoing thoracic surgery for lung cancer, showing elevated…
- Trial name
- PRESAGE (NCT01281787)
- Testing
- Metoprolol, Losartan
- Where
- Italy
- Volunteers
- 320 people
- Sponsor
- European Institute of Oncology
Sternotomy Wound
Wound Inflammatory Cells After Cardiac Surgery
One hundred patients, aged from 41 to 78 years, underwent open heart surgery in the years 1998-1999 and were studied by using the Cellstick device for harvesting wound inflammatory cells during the first 24 hours after surgery.
- Trial name
- NCT02875509
- Volunteers
- 100 people
- Sponsor
- Turku University Hospital
Pain, Post Operative
Pectointercostal Fascial Plane Block Versus Transversus Thoracic Plane Block In Adult Cardiac Surgery Patients
The study will be designed to compare the analgesic effect of ultrasound-guided pectointercostal fascial plane block versus tansversus thoracic plane block in adult cardiac surgery.
- Trial name
- NCT05323305
- Testing
- ultrasound guided regional block
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Alexandria University
Cardiac Surgical Procedures
Placement of Permanent Pacemaker Study
The purpose of this study is to determine the predictors for placement of permanent pacemakers soon after cardiac surgery. We will measure the following to see what influence, if any, they have on predicting the need for…
- Trial name
- NCT00512161
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- Weill Medical College of Cornell University
Cardiac Output, Hemodynamic Monitoring
Caretaker in the Cardiovascular Intensive Care Unit (CVICU)
To monitor the cardiac post-op patient population with both the pulmonary artery catheter (PAC) and the Caretaker monitor, which will seek to validate the Caretaker monitor against continuous CO via the PAC.
- Trial name
- NCT05779683
- Testing
- Caretaker Device placement
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Wake Forest University Health Sciences
Coronary Disease, Aortic Valve Stenosis
Quantitative Measurement of Myocardial Perfusion by Cardiac CT in Patients
It is a common understanding that patients with coronary heart disease are suffering, among others, from reduced myocardial perfusion.
- Trial name
- CCT/MPERF (NCT02361996)
- Where
- 3 sites in Austria, Russia and 1 more
- Volunteers
- 690 people
- Sponsor
- Bakulev Scientific Center of Cardiovascular Surgery
Delirium
Dexmedetomidine and IV Acetaminophen for the Prevention of Postoperative Delirium Following Cardiac Surgery
Investigators will assess the incidence and duration of postoperative delirium in patients ≥60 years old undergoing coronary artery bypass grafting (CABG), with/without valve surgery (aortic and/or mitral) based on different…
- Trial name
- DEXACET (NCT02546765)
- Testing
- IV acetaminophen & IV propofol, IV acetaminophen & IV dexmedetomidine
- Where
- United States
- Volunteers
- 140 people
- Sponsor
- Beth Israel Deaconess Medical Center
Acute Coronary Syndrome (ACS)
Maintenance of Platelet Inhibition With Cangrelor
The purpose of this study is to demonstrate that patients receiving cangrelor infusion before coronary artery bypass grafting have an acceptable safety profile and can undergo surgery without excessive bleeding peri-operatively.
- Trial name
- Bridge (NCT00767507)
- Testing
- cangrelor
- Where
- United States
- Volunteers
- 221 people
- Sponsor
- The Medicines Company