Clinical trials: Patients Undergoing Anaesthesia Induction
Geriatrics, Hypotension on Induction
Carotid Artery Corrected Flow Time and Inferior Vena Cava Collapsibility Index for Prediction of Hypotension After Induction of General Anesthesia in Geriatric Patients Undergoing Elective Surgery
In this observational study, we will assess cFT by Carotid ultrasound and IVC collapsibility index for prediction of hypotension after induction of general anesthesia in geriatric patients undergoing elective surgery.
- Conditions
- Geriatrics, Hypotension on Induction, General Anesthetic Drug Adverse Reaction, Elective Surgery
- Trial name
- NCT06814054
- Testing
- Carotid Artery Corrected Flow Time measurement, Inferior vena cava collapsibility index
- Where
- Egypt
- Volunteers
- 189 people
- Sponsor
- Tanta University
Geriatric Population, Spinal Anesthesia Induced Hypotension
HEIGHT-BASED AND CONVENTIONAL SPINAL ANAESTHETIC DOSING IN GERIATRIC PATIENTS
The goal of this clinical trial is to find out whether height-based dosing of spinal anaesthesia provides better hemodynamic stability and anesthetic outcome than conventional fixed dosing in elderly patients undergoing lower…
- Conditions
- Geriatric Population, Spinal Anesthesia Induced Hypotension, Spinal Anesthesia in Elderly Patients
- Trial name
- NCT07363941
- Testing
- Group A : Spinal Anaesthetic Dose, Group B : Conventional Dose
- Where
- Pakistan
- Volunteers
- 104 people
- Sponsor
- Shaheed Mohtarma Benazir Bhutto Institue of Trauma
Post-induction Hypotension (PIH)
Preoperative Caval-Aortic Index and Pleth Variability Index for Predicting Post-Induction Hypotension in Colorectal Surgery
This prospective observational study evaluated whether the preoperative caval-aortic index and pleth variability index can predict post-induction hypotension in adult patients undergoing elective colorectal surgery under general…
- Trial name
- NCT07876362
- Testing
- Preoperative Caval-Aortic Index and Pleth Variability Index Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 112 people
- Sponsor
- Dr. Lutfi Kirdar Kartal Training and Research Hospital
Hypotension Drug-Induced
Different Preloads for Prevention of Hypotension in Patients Undergoing Elective CS Under Intrathecal Anesthesia
The aim of this study was to compare between crystalloid versus crystalloid and colloid combination preloads for prevention of hypotension following intrathecal anaesthesia in patients undergoing elective Caesarean section.
- Trial name
- NCT03465943
- Testing
- Ringer, Voluven
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Assiut University
Seeing the Benefits of Using 4 Channel EEG During the DISE Procedure With Sedation
Evaluation of Anesthesia Depth Using 4-channel EEG in Patients Undergoing Drug-induced Sleep Endoscopy (DISE) With Two Different Sedation Methods.
You will undergo a drug-induced sleep endoscopy procedure. The drugs we use to create routine sedation will be used as medication.
- Trial name
- NCT06511128
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Ankara City Hospital Bilkent
Hemodynamics, Postoperative Recovery
Effect of Ciprofol Infusion for Induction and Maintenance on Hemodynamics and Postoperative Recovery
To study the Effect of Ciprofol Infusion for Induction and Maintenance of anesthesia on Hemodynamics and Postoperative Recovery in Patients Undergoing Thoracoscopic Lobectomy:a randomized, controlled trial.
- Conditions
- Hemodynamics, Postoperative Recovery, Anesthesia
- Trial name
- NCT05664386
- Testing
- propofol, ciprofol
- Where
- China
- Volunteers
- 126 people
- Sponsor
- Xiumei Song
Anesthesia, Blood Pressure
Norepinephrine Prevent Post-induction Hypotension in High-risk Patients
The investigators aimed to investigate the effects of continuous infusion of norepinephrine before and after general anesthesia induction on the occurrence of post-induction hypotension.
- Conditions
- Anesthesia, Blood Pressure, Norepinephrine
- Trial name
- NCT06028256
- Testing
- Norepinephrine Hydrochloride
- Volunteers
- 180 people
- Sponsor
- First Affiliated Hospital of Kunming Medical University
Urologic Diseases
Effect of Prewarming During Induction of General Anesthesia Combined With Warmed Intravenous Fluid on Core Temperature.
Hypothermia occurs frequently during general anesthesia. This study is to evaluate the efficacy of 10 minutes of prewarming during induction of general anesthesia during urologic surgery.
- Trial name
- NCT05636189
- Testing
- warming during induction of anesthesia, Prewarmed intravenous fluid administration
- Where
- South Korea
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Inje University
Spinal Cord Diseases
Anesthesia Induction in Patients Undergoing Surgery for Cervical Myelopathy
Aim of this trial is to compare propofol-based anaesthesia vs. sevoflurane-based anaesthesia induction in patients with cervical myelopathy receiving oral or nasal fiberoptic intubation.
- Trial name
- Blade runner (NCT01052337)
- Testing
- anaesthetics: sevofluorane
- Where
- Italy
- Volunteers
- 116 people
- Sponsor
- University of Roma La Sapienza
Apneic Oxygenation, High-flow Nasal Cannulae
High-flow Nasal Oxygenation in Obese Patients During Apnea
Before going off to sleep patients are given oxygen to saturate blood with oxygen to extend time before a decrease in the level of oxygen in the blood occurs.
- Conditions
- Apneic Oxygenation, High-flow Nasal Cannulae, Bariatric Surgery, Anesthesia Induction
- Trial name
- NCT03195504
- Testing
- HFNC, CON (control)
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- University Health Network, Toronto
Post Induction Hypotension
Effects of Esketamine and Bilateral Lower Limb Elevation on Hemodynamic Stability During Induction of General Anesthesia in Elderly Patients Undergoing Thoracic Surgery
Video-assisted thoracoscopic surgery (VATS) is widely used in thoracic surgery due to small incisions, low stress response, and high patient tolerance.
- Trial name
- NCT07374458
- Testing
- Esketamine, Bilateral Lower Limb Elevation
- Volunteers
- 292 people, healthy volunteers welcome
- Sponsor
- Nanjing First Hospital, Nanjing Medical University
Pharmacokinetics, Pharmacodynamics
Pharmacokinetics and Pharmacodynamics of Sugammadex in Reversal of Vecuronium-induced Neuromuscular Blockade
The purpose of this study is to illustrate pharmacokinetics and pharmacodynamics of sugammadex in reversal of vecuronium-induced neuromuscular blockade in anesthesia obese patients undergoing bariatric surgery.
- Trial name
- NCT04131218
- Testing
- Sugammadex
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Guangzhou General Hospital of Guangzhou Military Command
Anesthesia-induced Negative Hemodynamic Effects
Atropine-effect During Propofol/Remifentanil Induction
Remifentanil is a widely used potent intravenous opioid with the advantage of having a short time of action. Compared to other opiates however remifentanil generates more intense hemodynamic side-effects.
- Trial name
- NCT01871922
- Testing
- Atropine
- Where
- Netherlands
- Volunteers
- 60 people
- Sponsor
- University Medical Center Groningen
Hypotension, Anesthesia, General
Internal Jugular Vein Collapsibility Index for Predicting Post-Induction Hypotension
This study aims to investigate whether the Internal Jugular Vein Collapsibility Index (IJV-CI), measured via ultrasonography, can predict hypotension (low blood pressure) that occurs after the induction of general anesthesia.
- Conditions
- Hypotension, Anesthesia, General, Cholecystectomy, Laparoscopic
- Trial name
- IJV-CI (NCT07565025)
- Testing
- IJV-CI Measurement
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people
- Sponsor
- University of Gaziantep
Spinal Anesthesia-Induced Hypotension, Cerebral Oxygenation
Effects of Ondansetron Timing During Spinal Anesthesia for Urologic Surgery
This study will evaluate whether the timing of intravenous ondansetron administration affects cerebral oxygenation and hemodynamic stability in older adults undergoing endoscopic urologic surgery under spinal anesthesia.
- Trial name
- NCT07858149
- Testing
- Ondansetron 8 mg, 0.9 % sodium chloride
- Where
- Turkey (Türkiye)
- Volunteers
- 99 people
- Sponsor
- Istanbul University
Anesthesia
High Flow Oxygen in Patients Undergoing Surgery Under General Anesthesia
Preoxygenation remains an important determinant of morbidity and mortality in anesthesia despite advances in mask ventilation and difficult intubation management. 1.
- Trial name
- OPTIFLOW (NCT03554863)
- Testing
- Nasal High Flow Oxygen, Facial Mask
- Where
- 2 sites in France
- Volunteers
- 60 people
- Sponsor
- CMC Ambroise Paré
Coronary Artery Disease
Dynamic Arterial Elastance for Prediction of Vasopressor Requirement After Anesthesia Induction in Elective On-Pump CABG
This study aims to determine whether dynamic arterial elastance (EaDyn), measured after anesthesia induction, can predict the need for vasopressor treatment in patients undergoing elective on-pump coronary artery bypass graft…
- Trial name
- NCT07871201
- Testing
- No intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people
- Sponsor
- Elzem SEN
QLB vs TAPB, Quadratus Lumborum Block
Comparison of the Effects of Bilateral Transversus Abdominis Plane Block and Bilateral Quadratus Lumborum Block on Postoperative Analgesia in Patients Undergoing Midline Laparotomy
Midline incisions provide easy, rapid and excellent exposure of the abdominal cavity and are particularly used for complex, diagnostic or emergency procedures.
- Conditions
- QLB vs TAPB, Quadratus Lumborum Block, Transversus Abdominis Plane (TAP) Block
- Trial name
- NCT06950502
- Testing
- transversus abdominis plane block, Quadratus Lumborum Block (QLB), quadratus lumborum block using bupivacaine
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Ankara University
Pulmonary Edema, Acute Lung Injury
Fluid Management in the Post-Anesthetic Care Unit (PACU) at Sourasky Medical Center
Peri-operative fluid therapy is a controversial area with few randomized trials to guide practice. Fluid management has a significant influence on outcome following surgery.
- Conditions
- Pulmonary Edema, Acute Lung Injury, Hypertension, Renal Failure
- Trial name
- NCT00995228
- Where
- Israel
- Volunteers
- 1,000 people
- Sponsor
- Tel-Aviv Sourasky Medical Center
Cancer, Bladder, Surgery
3 Ultrasound Guided Plane Blocks for Perioperative Analgesia in Patients Undergoing Radical Cystectomy
Radical cystectomy is the gold standard treatment for muscle invasive bladder cancer as well as some T1 and non-invasive disease. It is a major operation with significant perioperative morbidity and complications.
- Conditions
- Cancer, Bladder, Surgery, Anesthesia, Analgesia
- Trial name
- NCT05278598
- Testing
- Erector Spinae Plane Block, Thoracic Paravertebral Plane Block, Quadratus Lumborum Plane Block
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Nazmy Edward Seif