Clinical trials: Patients Undergoing General Anesthesia
Posterior Fossa Tumor
Partial Scalp Block in Posterior Fossa Surgery
Pain in patients undergoing posterior fossa surgery is regarded as more intense when compared to pain in patients undergoing supratentorial cranial surgeries.
- Trial name
- NCT04955236
- Testing
- Partial scalp block, Fentanyl
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Kasr El Aini Hospital
Patients Undergoing Robotic Surgery
Quality of Recovery After Robotic Surgery
Robotic approach to laparoscopic surgery has greatly facilitated undertaking complex surgery inside the abdominal cavity with ease.
- Trial name
- NCT03659539
- Testing
- PROPOFOL, Desflurane
- Where
- India
- Volunteers
- 120 people
- Sponsor
- Nitin Sethi, DNB
Vitreoretinal Surgeries, Postoperative Nausea and Vomiting
SPI-directed Analgesia for Vitreoretinal Surgeries
The aim of this randomized trial is to assess the efficacy of SPI-directed analgesia for vitreoretinal surgeries (VRS), presence of PONV and oculocardiac reflex (OCR) and compare Numerical Rating Scale (NRS) with Surgical Pleth…
- Conditions
- Vitreoretinal Surgeries, Postoperative Nausea and Vomiting, Postoperative Pain
- Trial name
- SPIVS (NCT02973581)
- Testing
- Metamizol, Acetaminophen, 0,5 % bupivacaine with of 2% lidocaine
- Where
- Poland
- Volunteers
- 176 people
- Sponsor
- Medical University of Silesia
Difficult Intubation, Obesity
Modified El-Ganzouri Risk Index for Predicting Difficult Intubation in Obese Patients
This observational study aims to compare the predictive performance of the Modified El-Ganzouri Risk Index (MEGRI) incorporating anthropometric ratios with the original El-Ganzouri Risk Index (EGRI) for predicting difficult…
- Trial name
- MEGRI (NCT07857395)
- Testing
- No intervention
- Where
- Egypt
- Volunteers
- 114 people
- Sponsor
- Zagazig University
Head and Neck Neoplasm
Preoxygenation With a High-flow Nasal Cannula or a Simple Mask Before General Anesthesia in Head and Neck Surgery
Objectives: To assess arterial oxygen partial pressure (PaO2) at defined time points during the preoxygenation and to compare between high flow heated humidified nasal oxygen versus standard preoxygenation with oxygen insufflation…
- Trial name
- NCT03896906
- Testing
- High-flow nasal cannula, simple mask
- Where
- South Korea
- Volunteers
- 52 people
- Sponsor
- Asan Medical Center
Teeth, Impacted, Tooth-loss
The Influence of Sedation and General Anesthesia to Patients' Psycho-emotional State Undergoing Wisdom Teeth Extraction
The aim of the study is to evaluate, wheather the sedation or general anesthesia in third molar extractions influence the patient's psycho-emotional status.
- Conditions
- Teeth, Impacted, Tooth-loss, Anxiety, Fear
- Trial name
- NCT04259463
- Testing
- Third molars extraction
- Where
- Lithuania
- Volunteers
- 53 people
- Sponsor
- Inesa Astramskaitė
Neurocognitive Disorders, Neutrophil-Lymphocyte Ratio
NLR and PRL in Neurocognitive Disorders
Preliminary evidence suggest a possible relationship between Neutrophil-Lymphocyte Ratio (NLR) and Platelet-Lymphocyte Ratio (PLR) and perioperative neurocognitive disorders (NCD).
- Conditions
- Neurocognitive Disorders, Neutrophil-Lymphocyte Ratio, Platelet-Lymphocyte Ratio
- Trial name
- NCT04736290
- Testing
- NLR, PLR
- Where
- Greece
- Volunteers
- 288 people
- Sponsor
- University of Thessaly
Postoperative Agitation, Emergence Delirium, Anesthesia
Impact of Neuromonitoring on Postoperative Agitation in Pediatric General Anesthesia
Postoperative agitation is frequently observed in the pediatric patient group following general anesthesia. The exact cause of this agitation has not been clearly determined; however, it may be associated with various factors…
- Trial name
- NCT07243990
- Testing
- dsa intervention group, Traditional Monitoring
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Sakarya University
Tympanoplasty Surgery, Laryngeal Mask Airway
Comparative of Video Laryngeal Mask and Endotracheal Intubation in Patients Undergoing Tympanoplasty Surgery.
The effects of video laryngeal mask and endotracheal intubation on hemodynamic parameters and the development of postoperative respiratory complications in participants scheduled for tympanoplasty will be evaluated.
- Trial name
- NCT07084636
- Testing
- Video Laryngeal Mask, Endotracheal intubation
- Where
- Turkey (Türkiye)
- Volunteers
- 98 people
- Sponsor
- Samsun University
Induction and Maintenance of General Anesthesia
A Study to Evaluate the Efficacy and Safety of HSK3486 in the Induction of General Anesthesia
This is a multi-center, randomized, single-blind, propofol injectable emulsion parallel-controlled Phase III clinical study. A total of patients undergoing elective surgery are intended to be enrolled and randomly assigned to…
- Trial name
- NCT04511728
- Testing
- HSK3486, Propofol
- Where
- China
- Volunteers
- 129 people
- Sponsor
- Haisco Pharmaceutical Group Co., Ltd.
Heart Disease
Assessment of Cardiac Function and Anesthesia Depth in Patients Undergoing Cardiac Surgery
The SHAPE study is a prospective, randomized study evaluating changes in cardiac function in adult patients undergoing cardiac surgery with cardiopulmonary bypass.
- Trial name
- SHAPE (NCT07770269)
- Testing
- BIS-guided anesthesia: BIS 45-55, BIS-guided anesthesia: BIS 30-35
- Where
- Greece
- Volunteers
- 70 people
- Sponsor
- AHEPA University Hospital
General Anesthesia, Postoperative Pain
Preoperative Anxiety on Postoperative Outcome and Sleep Quality in Patients Undergoing Laparoscopic Hysterectomy
Sleep is a naturally occurring state of decreased arousal that is crucial for normal immune and cognitive function. Although surgery and anesthesia techniques have improved in recent years, sleep function and sleep cycles may…
- Conditions
- General Anesthesia, Postoperative Pain, Postoperative Sleep Quality, Preoperative Anxiety
- Trial name
- NCT04619979
- Testing
- patients undergoing gynecological surgery under general anesthesia
- Where
- China
- Volunteers
- 356 people
- Sponsor
- Shengjing Hospital
Loss of Consciousness
Remimazolam Bolus for General Anesthesia
It is important to estimate the adequate dose of remimazolam intravenous bolus injection to induce the loss of consciousness. We will determine the ED50 and ED95 of remimazolam intravenous bolus on the loss of consciousness in…
- Trial name
- NCT04901871
- Testing
- 0.02 mg/kg, age<65, 0.07 mg/kg, age<65, 0.12 mg/kg, age<65
- Where
- South Korea
- Volunteers
- 120 people
- Sponsor
- Gangnam Severance Hospital
Postoperative Atelectasis
Supine vs Prone Position and Atelectasis Assessed by Lung Ultrasound
Atelectasis frequently develops during and after general anesthesia due to factors such as anesthesia-induced diaphragmatic dysfunction, reduced functional residual capacity, altered ventilation-perfusion matching, and surgical…
- Trial name
- LUS-ATELEC (NCT07320092)
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Anesthesia, Hip Osteoarthritis
The Assessments of the Postoperative Recovery on Elderly Patients Received General Anesthesia or Peripheral Nerve Blocks
Postoperative recovery is always worrisome to the elder patients undergoing Total Hip Replacement (THR). Peripheral Nerve Blocks (PNBs), lumbar plexus block combined with sciatic nerve blocks, may be alterative anaesthesia style…
- Trial name
- NCT01782612
- Testing
- Multimodal analgesic techniques, Total uni-Hip Replacement
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Junle Liu
Postoperative Pain, Anesthesia
Regional Anesthesia Versus General Anesthesia
Patients undergoing laparoscopic gynecological surgery will receive regional anesthesia or general anesthesia with endotracheal intubation.
- Trial name
- NCT03830086
- Testing
- Midazolam, Sufentanil, Propofol
- Where
- 2 sites in Italy
- Volunteers
- 28 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Diabetic Autonomic Neuropathy Type 2, Perioperative Complication
Effect of Diabetes Mellitus on Cardiac Autonomic Function in Surgical Patients Undergoing General Anesthesia
Because autonomic neuropathy affects the constriction of thermoregulatory blood vessels, it is more difficult for diabetic patients to maintain their own body temperature in cold environments than normal people, and therefore it…
- Conditions
- Diabetic Autonomic Neuropathy Type 2, Perioperative Complication, Temperature Change, Body
- Trial name
- NCT06432270
- Volunteers
- 388 people, healthy volunteers welcome
- Sponsor
- Zhujiang Hospital
Inflammatory Response
Effect of Intravenous Ibuprofen on Inflammatory Responses in Patients Undergoing Surgery With General Anesthesia.
The administration of anti-inflammatory drugs such as ibuprofen before and after surgery has not been studied extensively. Subjects are being asked to participate in this study because they are scheduled for surgery and because…
- Trial name
- NCT01377441
- Testing
- Ibuprofen
- Where
- 2 sites in United States
- Volunteers
- 6 people
- Sponsor
- NYU Langone Health
Anesthesia, General
A Study to Assess Indices of SNAP vs VISTA on Surgical Patients Undergoing General Anesthesia
Establish the range of index values for the SNAP II corresponding to each anesthetic state studied.
- Trial name
- Precision GA (NCT00829803)
- Testing
- SNAP monitor; Bispectral Index Monitor (BIS Monitor)
- Where
- 4 sites in United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Stryker Instruments
Major Adverse Cardiac Events, Adverse Effect of Unspecified General Anesthetic
Adverse Events in Acute Limb Ischemic Patient Undergoing Revascularization
Acute limb ischemia is one of the devastating vascular emergencies that lead to life and limb loss if the appropriate treatment is not reached.The revascularization is a cornerstone in treating acute limb ischemia.
- Trial name
- NCT05362266
- Where
- 2 sites in Thailand
- Volunteers
- 240 people
- Sponsor
- Mahidol University