Clinical trials: Patients Undergoing General Anesthesia
Thoracoscopic Surgery
Preservation of Spontaneous Breathing in Patients Undergoing Thoracoscopic Surgery
the aim of this study is to evaluate the advantages of the non-intubation compared with intubation anesthesia on enhanced recovery after thoracoscopic surgery
- Trial name
- NCT05595096
- Testing
- General anesthesia with preservation of spontaneous breathing
- Where
- China
- Volunteers
- 59 people
- Sponsor
- Zhenjiang First People's Hospital
Phantom Limb Pain, Amputation
Effect of Femoral and Sciatic Nerve Blocks, Combined with General Anesthesia, in Postoperative Pain Levels and Phantom Limb Pain Development in Patients Undergoing Lower Limb Amputation
The goal of this observational study is to determine the effect of femoral and sciatic nerve blocks, combined with general anesthesia, in postoperative pain levels and phantom limb pain development in patients undergoing lower…
- Conditions
- Phantom Limb Pain, Amputation, Anesthesia, Local
- Trial name
- NCT06693427
- Testing
- Peripheral Nerve Block
- Where
- Greece
- Volunteers
- 72 people
- Sponsor
- DIMITRIOS KATSAROS
Vitreoretinal Surgeries, Postoperative Nausea and Vomiting
Paracetamol and Metamizole With SPI-guided Anaesthesia for VRS
The aim of this randomized trial is to assess the efficacy of preemptive analgesia using paracetamol or metamizole or both of them under SPI-guided anaesthesia for vitreoretinal surgery (VRS), presence of PONV (postoperative…
- Conditions
- Vitreoretinal Surgeries, Postoperative Nausea and Vomiting, Postoperative Pain
- Trial name
- P&MSPIVRS (NCT03389243)
- Testing
- Metamizol, paracetamol, paracetamol and metamizole
- Where
- Poland
- Volunteers
- 165 people
- Sponsor
- Medical University of Silesia
Hypotension on Induction
FloPatch for Prevention of Hypotension After Induction of General Anesthesia
This study is being conducted to find out if a special device called FloPatch™, which sticks to a persons skin and uses ultrasound to check the blood flow in their neck, can tell if someone going to have low blood pressure after…
- Trial name
- HI-CAP (NCT06316817)
- Testing
- FloPatch
- Where
- Canada
- Volunteers
- 172 people
- Sponsor
- Mount Sinai Hospital, Canada
Orthopedic Disorder, Total Knee Replacement
Combined Adductor&Sciatic Nerve Block vs Femoral&Sciatic Nerve Block in Total Knee Replacement Surgery
Knee joints, one of the largest and most functional joints of the human body, have great features to provide ideal body posture and movement.
- Conditions
- Orthopedic Disorder, Total Knee Replacement, Post Operative Pain, Surgery
- Trial name
- NCT05648708
- Testing
- Combine Adductor Canal & Sciatic Nerve Block, Combine Femoral & Sciatic Nerve Block, Bupivacaine and prilocaine hydrochloride
- Where
- Turkey (Türkiye)
- Volunteers
- 68 people
- Sponsor
- Bakirkoy Dr. Sadi Konuk Research and Training Hospital
Diastolic Dysfunction, Coronary Artery Disease
Study of the Effect of Inhaled Anesthetics on Diastolic Heart Function Using a Doppler-derived Efficiency Index
The purpose of this study is to determine the effect of inhaled anesthetic drugs upon diastolic heart function (heart suction and filling performance) in patients who are undergoing coronary bypass surgery.
- Conditions
- Diastolic Dysfunction, Coronary Artery Disease, General Anesthesia
- Trial name
- NCT00907439
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- Washington University School of Medicine
Residual Neuromuscular Blockade, Diaphragm Dysfunction
Diaphragm Ultrasound and Neuromuscular Monitoring for Predicting Early Respiratory Events After Extubation
The goal of this prospective observational study is to learn whether diaphragm ultrasound and quantitative neuromuscular monitoring can predict early respiratory events after extubation in adults having elective surgery under…
- Conditions
- Residual Neuromuscular Blockade, Diaphragm Dysfunction, Postoperative Pulmonary Complications, Airway Extubation
- Trial name
- DIAPHEX (NCT07912437)
- Testing
- Diaphragm ultrasonography4
- Volunteers
- 100 people
- Sponsor
- Mustafa Duran
Inflammation Biomarkers, Quality of Recovery (QoR-15)
Comparison of Inflammatory Factors, Pain Scale, and Postoperative Recovery Quality (QOR - 15) in Patients Undergoing Colorectal Cancer Surgery with Conventional General Anesthesia Techniques Compared to General Anesthesia Combined with Epidural Anesthesia At Prof. Ngoerah Hospital
Surgery can increase IL-6 cytokines, triggering inflammation and metastasis. The combination of general and epidural anesthesia has the potential to suppress IL-6, improve the tumor microenvironment, provide analgesia, and…
- Conditions
- Inflammation Biomarkers, Quality of Recovery (QoR-15), Visual Analog Pain Scale
- Trial name
- NCT06784258
- Testing
- General Anesthesia (control group), General Anesthesia combined with epidural anesthesia
- Where
- Indonesia
- Volunteers
- 44 people
- Sponsor
- Udayana University
Pharyngitis
Combined Effect of Dexamethasone and Paracetamol for Postoperative Sore Throat
The investigators want to evaluate the efficacy of the dexamethasone and paracetamol for the prevention of postoperative sore throat.
- Trial name
- NCT02252419
- Testing
- Dexamethasone, Paracetamol
- Where
- South Korea
- Volunteers
- 242 people
- Sponsor
- Seoul National University Hospital
Postoperative Recovery, Pediatric Anesthesia
Timing of Aminophylline and Recovery in Pediatric Ambulatory Surgery
Beyond its established use as a bronchodilator and therapy for apnea of prematurity, aminophylline has demonstrated utility in reversing the effects of anesthetics, enhancing recovery by accelerating respiratory and cognitive…
- Conditions
- Postoperative Recovery, Pediatric Anesthesia, Ambulatory Surgery
- Trial name
- ELEAR-PAP (NCT07011134)
- Testing
- Group (E): receive aminophylline early intraoperatively,, Group (L) received aminophylline late intraoperatively, Group (C) will receive normal saline post-anesthetic discontinuation.
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Hany Mohammed El-Hadi Shoukat Mohammed
Magnetic Resonance Imaging
Prospective Study Assessing the Validity of Y-PAS (Yale Preoperative Anxiety Scale) to Predict Patients Undergoing Magnetic Resonance Imaging Without the Use of Sedation/General Anesthesia
The mYPAS (Modified Yale Preoperative Anxiety Scale) is a quick, easy, validated and "gold standard" assessment tool to measure pediatric anxiety in the perioperative period.
- Trial name
- NCT02586103
- Testing
- MRI simulation
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Arlyne Thung
Cervical Incompetence
Comparison of Anesthesia Type in Patients Undergoing Transabdominal Cervico Isthmic Cerclage (TCIC)
The investigator aimed to compare the effect of anesthesia on overall postoperative outcomes including post-operative pain score and the fetal well-being (heart rate) in patients undergoing transabdominal cervico isthmic…
- Trial name
- NCT03636048
- Testing
- Bupivacaine Hcl 0.5% Inj, Propofol 10 milligram/ML
- Where
- South Korea
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Hallym University Kangnam Sacred Heart Hospital
Anesthesia; Functional
Evaluation of Oxygenation Parameters in Patients Undergoing Rhinoplasty Under General Anesthesia
The investigators are planning to compare the oxygenation values (Pao2/fio2, lactate etc.) in patients who underwent TCI and inhalation anesthesia in rhinoplasty operation.
- Trial name
- NCT05754515
- Testing
- target controlled infusion (TCI) group
- Where
- Turkey (Türkiye)
- Volunteers
- 106 people
- Sponsor
- Duzce University
Smooth Extubation
Smooth Extubation With Magnesium Sulphate for General Anesthesia With Endotracheal Intubation
Tracheal extubation is a critical event in the anaesthetic management of patients undergoing general anaesthesia with endotracheal intubation for elective procedures.
- Trial name
- NCT04617652
- Testing
- Magnesium sulfate, Normal saline
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Fayoum University Hospital
Day Surgery
Ramosetron OD Tablet and Postdischarge Nausea and Vomiting
Postoperative nausea and vomiting after general anesthesia is one of the common anesthetic complications. If the patient is discharged from the hospital after surgery, proper treatment may be delayed or impossible if nausea and…
- Trial name
- NCT04297293
- Testing
- Ramosetron
- Where
- South Korea
- Volunteers
- 138 people
- Sponsor
- Seoul National University Hospital
Postoperative Pain
Effect of Noise Blocking During General Anesthesia on Postoperative Pain
To investigate the effect of noise blocking during general anesthesia on postoperative pain in patients undergoing laparoscopic abdominal surgery.
- Trial name
- NCT05540691
- Testing
- Wear noise-cancelling earphones
- Where
- China
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- The Second Affiliated Hospital of Chongqing Medical University
Ventilation, Lung Function
Respiratory Effects of Flow-Controlled Ventilation and Jet Ventilation in Patients Undergoing Laryngotracheal Surgery
Laryngotracheal surgery often requires a small diameter endotracheal tube to oxygenate patients under general anesthesia. Oxygenation is often only possible with high-frequency jet ventilators due to the use of small diameter and…
- Conditions
- Ventilation, Lung Function, Anesthesia, General
- Trial name
- Flowjet (NCT06063798)
- Testing
- General anesthesia for laryngotracheal surgery, Mechanical ventilation by FCV, Mechanical ventilation by HFJV
- Where
- Switzerland
- Volunteers
- 50 people
- Sponsor
- University Hospital, Geneva
Anesthesia, General, Anesthesia, Spinal
The Effect of General and Spinal Anesthesia on Neutrophil-to-lymphocyte Ratio
The aim of the study was to evaluate the effects of anesthetic techniques (general and spinal anesthesia) on umbilical cord neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR) and mean platelet volume (MPV)…
- Conditions
- Anesthesia, General, Anesthesia, Spinal, Umbilical Cord
- Trial name
- NCT05409885
- Testing
- General anesthesia, Spinal anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Antalya Training and Research Hospital
Laryngoscopy, Apnea
High Flow Oxygen in Patients Undergoing Suspension Laryngoscopy Under General Anesthesia
Patients undergoing suspension laryngoscopy under general anaesthesia have oxygen delivered to their lungs through different methods. Inserting a tube in the trachea is the best means for oxygen delivery.
- Conditions
- Laryngoscopy, Apnea, Anesthesia
- Trial name
- OxALa (NCT03472118)
- Testing
- Nasal High Flow Oxygen
- Where
- 2 sites in France
- Volunteers
- 29 people
- Sponsor
- CMC Ambroise Paré
Supraglottic Airway Device
A Comparison of the I-gel and Self-pressurised Air-Q Intubating Laryngeal Airway (Air-Q sp) in the Elderly Patients
Supraglottic airway devices (SADs) are well established in anesthetic practice. Among these devices, the i-gel has been typically widely used.
- Trial name
- NCT02260427
- Testing
- Insertion of the i-gel, Insertion of the air-Q sp
- Where
- South Korea
- Volunteers
- 100 people
- Sponsor
- Yonsei University