Clinical trials: Patients Undergoing General Anesthesia
Trauma; Complications, Aspiration
Gastric Ultrasound in Pediatric Trauma Patients
Gastric ultrasound has become increasingly utilized to examine volume and quality of gastric contents in the preoperative setting to guide anesthetic management and relay risk of aspiration in both adult and pediatric medicine.
- Trial name
- NCT05330351
- Testing
- Gastric Ultrasound
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Children's Hospital of Philadelphia
Post Operative Delirium
Effect of Anesthesia on Post-operative Delirium in Elderly Patients Undergoing Hip Fracture Surgery
The purpose of this study is evaluate postoperative delirium after general anesthesia and regional anesthesia in elderly patients undergoing hip fracture surgery.
- Trial name
- RAGADelirium (NCT02213380)
- Testing
- method of anesthesia
- Where
- 13 sites in China
- Volunteers
- 950 people
- Sponsor
- Wenzhou Medical University
Carbohydrate Intolerance, Diabetes Mellitus Type 2
Safety of Preoperative Carbohydrate Loading in Diabetic Patients
The purpose of this study is to investigate the safety of preoperative carbohydrate loading in diabetic patients undergoing general anesthesia
- Trial name
- NoNPO (NCT04456166)
- Testing
- noNPO
- Where
- South Korea
- Volunteers
- 60 people
- Sponsor
- Seoul National University Hospital
Gynecological Surgery
Effect of Combined Administration of Sevoflurane and Remimazolam on Emergence
Enhanced recovery after surgery (ERAS) protocols are being explored to improve patient outcomes. The method of inducing anesthesia and maintenance using inhalation anesthetics is common but may delay recovery.
- Trial name
- NCT06385002
- Testing
- Remimazolam
- Where
- South Korea
- Volunteers
- 146 people, healthy volunteers welcome
- Sponsor
- Pusan National University Yangsan Hospital
Sex Differences, Postoperative Sleep Quality
Sex Difference Effects on Postoperative Sleep, Inflammation and Cognition in Patients Undergoing General Anesthesia
Video-Assisted Thoracoscopic Surgery(VATS) is among the most common and disabling persistent pain and inflammation conditions, with increasing prevalence in the developed world, and affects women to a greater degree than men.
- Conditions
- Sex Differences, Postoperative Sleep Quality, Postoperative Pain, Inflammation Function
- Trial name
- NCT05059548
- Testing
- Video-Assisted Thoracoscopic Surgery
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Shengjing Hospital
Fraily, Abdominal Surgery
Awareness Neuraxial Versus General Anesthesia in Frail Patients Undergoing Laparoscopic or Robotic Abdominopelvic Surgery.
This is a bicentric, prospective, non-pharmacological, randomized study designed to compare the efficacy and safety of awake neuraxial anesthesia with sedation versus general anesthesia in frail patients undergoing elective major…
- Conditions
- Fraily, Abdominal Surgery, Postoperative Cognitive Dysfunction (POCD)
- Trial name
- SAFE-AWARENESS (NCT07486336)
- Testing
- Neuraxial anesthesia, General Anesthesia, avoidance of GABAergic-drugs strategy
- Where
- 2 sites in Italy
- Volunteers
- 100 people
- Sponsor
- Ente Ospedaliero Ospedali Galliera
Osteoarthritis
General or Regional Anesthesia for Hip Surgery
The purpose of this study is to determine whether general anaesthesia or regional anaesthesia is best for patients undergoing Total Hip Arthroplasty.
- Trial name
- NCT01733472
- Testing
- GA-arm, remifentanil, RA-arm
- Where
- Sweden
- Volunteers
- 120 people
- Sponsor
- Region Skane
Hypotension
Efficacy of Dexamethasone in Attenuation of Postinduction Hypotension in Geriatric Patients Undergoing General Anesthesia
Geriatric patients who undergo general anesthesia experience post induction hypotension which is treated with intravenous fluids and ephedrine.
- Trial name
- NCT04908592
- Testing
- Dexamethasone
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Ain Shams University
Obesity, Bariatric Surgery
Swap Anesthetic Versus Continuous Desflurane in Adults Undergoing Bariatric Surgery
This randomized, parallel-group, non-inferiority clinical trial aims to evaluate whether an anesthetic swap strategy consisting of sevoflurane followed by desflurane 30 minutes before the end of surgery is non-inferior to…
- Trial name
- SWAP (NCT07748247)
- Testing
- Desflurane, Sevoflurane-Desflurane
- Where
- Chile
- Volunteers
- 82 people
- Sponsor
- Clínica Dávila
Asthma
Influence of Propofol on Alveolar Macrophage in Asthmatic Patients
The change of airway responsiveness and alveolar macrophage (AM) immunity occurs during the pathogenesis of asthma. Macrophage-associated airway protection in patients with asthma is affected positively or negatively by propofol…
- Trial name
- PAMAP (NCT00676416)
- Testing
- 2,6-Diisopropylphenol
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Nanjing Medical University
Hernia Abdominal Wall
Remifentanil in Deep vs Moderate Neuromuscular Blocks During Surgical Pleth Index-guided Anesthesia for Laparoscopic Herniorrhaphy
The primary purpose of this study is to compare the remifentanil requirements in deep versus moderate neuromuscular blocks during the surgical pleth index -guided anesthesia in patients undergoing laparoscopic herniorrhaphy.
- Trial name
- NCT04022733
- Testing
- Moderate neuromuscular block, Deep neuromuscular block
- Where
- South Korea
- Volunteers
- 134 people
- Sponsor
- Ajou University School of Medicine
Cholecystitis
Video Laryngeal Mask Versus Endotracheal Tube Undergoing Laparoscopic Cholecystectomy Surgery
The aim of this study is to investigate the effectiveness of using a video laryngeal mask for airway management in patients undergoing laparoscopic cholecystectomy.
- Trial name
- NCT06502028
- Testing
- Video laryngeal mask airway, Endotracheal tube
- Where
- South Korea
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Cognitive Change, Total Knee Anthroplasty
Early Cognitive Changes After General Versus Spinal Anesthesia in Older Adults Undergoing Total Knee Arthroplasty
This prospective observational study investigated early postoperative cognitive changes in older adults undergoing elective total knee arthroplasty under general or spinal anesthesia.
- Trial name
- NCT07860593
- Testing
- General Anesthesia, Spinal Anesthesia with Bupivacaine
- Where
- Turkey (Türkiye)
- Volunteers
- 44 people
- Sponsor
- Haseki Training and Research Hospital
Gastrectomy
A Comparison of Dexmedetomidine and Epidural Anesthesia Under General Anesthesia in Patients Undergoing Gastrectomy
Clinically, combining epidural with general anaesthesia may confer many advantages to patients undergoing major thoracic, abdominal or orthopaedic surgery.
- Trial name
- NCT01657812
- Testing
- dexmedetomidine
- Where
- China
- Volunteers
- 90 people
- Sponsor
- Anhui Medical University
Postoperative Residual Curarization, Neuromuscular Block
Reversal With Low Doses of Sugammadex in Patients Undergoing Non-cardiac Surgery
Neuromuscular blocking agents (NMBA) are among the most commonly used drugs during general anesthesia and may induce complete muscle paralysis.They are used clinically to facilitate endotracheal intubation and to optimize…
- Trial name
- NCT03460509
- Testing
- Sugammadex
- Volunteers
- 144 people
- Sponsor
- The Hospital of Vestfold
Patients Undergoing General Anesthesia
A Comparative Study of the Next-Generation TetraGraph® and Mechanomyography Neuromuscular Monitors in Clinical Settings
Background: Neuromuscular monitoring plays a critical role in reducing postoperative residual neuromuscular blockade (PRNB), a significant risk factor for respiratory complications.
- Trial name
- MMG vs EMG NG (NCT07750405)
- Testing
- Mechanomiograph (MMG), Electromiograph (EMG)
- Where
- Hungary
- Volunteers
- 20 people
- Sponsor
- University of Debrecen
Breast Cancer Female
GENe EXpression After Regional or General ANesthesia in Patients Undergoing Breast Cancer Surgery
Breast cancer is the most commonly diagnosed cancer in females and the second leading cause of death from cancer in women. It was estimated that 2 million new cases have occurred in 2018 worldwide 1.
- Trial name
- GENEXAN (NCT03779685)
- Testing
- General anesthesia, Regional anesthesia
- Volunteers
- 100 people
- Sponsor
- Azienda Ospedaliera San Gerardo di Monza
Acute Stroke
Impact of Anesthesia Type on Outcome in Patients With Acute Ischemic Stroke (AIS) Undergoing Endovascular Treatment
Recent observational studies have found an association between general anaesthesia and increased post-operative mortality in acute ischemic stroke patients undergoing endovascular treatment.
- Trial name
- CANVAS (NCT02677415)
- Testing
- Intravenous anesthetics, local anesthesia, Controlled ventilation
- Where
- China
- Volunteers
- 640 people
- Sponsor
- Beijing Tiantan Hospital
Inflammatory Response in Total Knee Arthroplasty
Spinal Versus General Anesthesia and Inflammatory Response Measured by Delta Neutrophil Index in Total Knee Arthroplasty: An Observational Study
This study aims to compare the effects of spinal versus general anesthesia on the inflammatory response measured by Delta Neutrophil Index (DNI) in patients undergoing total knee arthroplasty.
- Trial name
- DNA-TKA (NCT07214558)
- Testing
- Routine Clinical Anesthesia Practice
- Where
- Turkey (Türkiye)
- Volunteers
- 84 people
- Sponsor
- Elazıg Fethi Sekin Sehir Hastanesi
Gastrostomy
Transversus Abdominis Plane Block on Stress Response
This study evaluates the effect of transversus abdominis plane(TAP) block combined with general anesthesia on perioperative stress response in patients undergoing radical gastrectomy.
- Trial name
- NCT03035916
- Testing
- Transversus abdominis plane block, Epidural anesthesia, control
- Where
- China
- Volunteers
- 91 people
- Sponsor
- Jilin University