Clinical trials: Patients Undergoing General Anesthesia
Lumbar Spine Fusion Surgery
Multimodal GA for Lumbar Spine Surgery
To evaluate the effects of multimodal general anesthesia on the recovery profile of elder patients undergoing lumbar spine fusion surgery.
- Trial name
- NCT05247177
- Testing
- dexmedetomidine, ketamine co-administration with sevoflurane for general anesthesia, Conventional general anesthesia by administration of sevoflurane alone
- Where
- Taiwan
- Volunteers
- 100 people
- Sponsor
- National Taiwan University Hospital
Postoperative Recovery, Anesthesia, General
Quality of Recovery-15 After Opioid-free Versus Opioid-based General Anesthesia in Major Urological Surgery
This randomized controlled trial evaluates postoperative quality of recovery assessed with the Quality of Recovery-15 questionnaire in adult patients undergoing elective major urological surgery under opioid-free versus…
- Conditions
- Postoperative Recovery, Anesthesia, General, Analgesics, Opioid, Urologic Surgical Procedure
- Trial name
- QoR-OFA-URO (NCT07665463)
- Testing
- Remifentanil-based general anesthesia, Opioid-free general anesthesia
- Where
- Poland
- Volunteers
- 200 people
- Sponsor
- Jagiellonian University
Postoperative Cognitive Dysfunction
Dexamethasone for the Prevention of Postoperative Cognitive Dysfunction
This study aims to evaluate the possible effect of dexamethasone on prevention of cognitive dysfunction in the postoperative period of elderly patients undergoing to surgery under general anesthesia.
- Trial name
- NCT01332812
- Testing
- Dexamethasone, control group
- Where
- Brazil
- Volunteers
- 300 people
- Sponsor
- University of Sao Paulo
Surgery
The Clinical Efficacy of Supraglottic Airway Device, Self-pressurized Air-Q Intubating Laryngeal Airway (ILA -SP) in Adult Patients: Comparison With Classic-laryngeal Airway (c-LMA)
Supraglottic airway devices (SADs) are well established in anesthetic practice. Among these devices ,classic laryngeal airway has been typically widely used.
- Trial name
- NCT02206438
- Testing
- Insertion of C-LMA, Insertion of air-Q according
- Where
- South Korea
- Volunteers
- 84 people
- Sponsor
- Yonsei University
Remimazolam, Desflurane
Remimazolam vs Propofol as an Induction Agent for Morbid Obesity Patients
It is known that morbidly obese patients are often accompanied by cardiovascular complications such as hypertension, cardiac hypertrophy, and diastolic dysfunction, and are known to increase the risk of hypotension during…
- Conditions
- Remimazolam, Desflurane, Morbid Obesity, Sleeve Gastrectomy
- Trial name
- NCT05856617
- Testing
- Remimazolam besylate
- Where
- South Korea
- Volunteers
- 88 people
- Sponsor
- Seoul National University Bundang Hospital
Phantom Limb Pain, Amputation
Effect of Femoral and Sciatic Nerve Blocks, Combined with General Anesthesia, in Postoperative Pain Levels and Phantom Limb Pain Development in Patients Undergoing Lower Limb Amputation
The goal of this observational study is to determine the effect of femoral and sciatic nerve blocks, combined with general anesthesia, in postoperative pain levels and phantom limb pain development in patients undergoing lower…
- Conditions
- Phantom Limb Pain, Amputation, Anesthesia, Local
- Trial name
- NCT06693427
- Testing
- Peripheral Nerve Block
- Where
- Greece
- Volunteers
- 72 people
- Sponsor
- DIMITRIOS KATSAROS
General Anesthetic Drug Adverse Reaction
PKPD of Rocuronium and Sugammadex Profile in Pediatric Patients
The aim of the study is to assess the pharmacokinetic and pharmacodynamic properties of rocuronium and sugammadex and their clinical effect in the terms of both the relaxation of paralysed muscles (rocuronium) and the reversal of…
- Trial name
- NCT04851574
- Testing
- Sugammadex Injection
- Where
- Poland
- Volunteers
- 37 people
- Sponsor
- Poznan University of Medical Sciences
Urinary Surgery, General Anesthesia
Different Anesthesia Maintain Protocol Effect the Outcome of the Patients
This prospective open-label randomized study, patients were having elective urological surgery scheduled to last longer than 1 h under necessitating general anesthesia.Group-P: (Propofol group): 3 mg kg-1 min-1 propofol was…
- Trial name
- NCT04443946
- Testing
- Propofol, 1% Sevoflurane, 1% Sevoflurane continue
- Where
- China
- Volunteers
- 50 people
- Sponsor
- China International Neuroscience Institution
Posterior Fossa Tumor
Partial Scalp Block in Posterior Fossa Surgery
Pain in patients undergoing posterior fossa surgery is regarded as more intense when compared to pain in patients undergoing supratentorial cranial surgeries.
- Trial name
- NCT04955236
- Testing
- Partial scalp block, Fentanyl
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Kasr El Aini Hospital
Anesthesia, Neuromuscular Blockade
Measurement of Blood Loss in Adenotonsillectomy During General Anesthesia According to the Application of Nondepolarizing Muscle Relaxants
Although tonsillectomy is one of the most commonly performed surgeries, a review of literature reveals no articles dealing with the study of intraoperative blood loss in tonsillectomy and adenotonsillectomy according to the use…
- Conditions
- Anesthesia, Neuromuscular Blockade, Intraoperative Bleeding, Intraoperative Blood Loss
- Trial name
- NCT06399445
- Testing
- conventional cold tonsillectomy and curettage adenoidectomy, Rocuronium Bromide
- Where
- Croatia
- Volunteers
- 60 people
- Sponsor
- University Hospital of Split
Teeth, Impacted, Tooth-loss
The Influence of Sedation and General Anesthesia to Patients' Psycho-emotional State Undergoing Wisdom Teeth Extraction
The aim of the study is to evaluate, wheather the sedation or general anesthesia in third molar extractions influence the patient's psycho-emotional status.
- Conditions
- Teeth, Impacted, Tooth-loss, Anxiety, Fear
- Trial name
- NCT04259463
- Testing
- Third molars extraction
- Where
- Lithuania
- Volunteers
- 53 people
- Sponsor
- Inesa Astramskaitė
Etomidate is Mixed With Propofol
Etomidate/Propofol Mixture or Propofol Monotherapy Use in Patients Undergoing General Anesthesia
The purpose of this study was to investigate the effects of different proportions of etomidate/propofol mixture and propofol alone intravenous anesthesia on intraoperative and postoperative physiological indicators and…
- Trial name
- NCT03855267
- Testing
- Propofol 20 MG/ML, Propofol 20 mg/ml , etomidate 2 mg/ml
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Guolin Wang
Anesthesia
TEAS to Improve Outcome During Emergence From General Anesthesia After Robotic Surgery
This study is to observe whether transcutaneous electrical stimulation at specific acupoints could improve the quality of emergence in patients undergoing robotic laparoscopic gynecologic surgery.
- Trial name
- TIGER (NCT02323958)
- Testing
- acupoint stimulation, non-acupoint stimulation, electrode attached
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Air Force Military Medical University, China
Undergoing General Anaesthesia
Risk Factors of POCD in General Anesthesia Patients Underwent Noncardiac and Non Neurological Procedures.
The study was a prospective cohort study to assess the effect of age, duration of anesthesia, repeated surgery, and type of surgery on cognitive impairment in 108 geriatric patients (≥60 years) who underwent general anesthesia…
- Trial name
- NCT04215263
- Testing
- Questionaire
- Where
- Indonesia
- Volunteers
- 109 people
- Sponsor
- Universitas Indonesia
Postoperative Pain
Adductor Canal Block (ACB) Versus ACB /Saphenous Block in Patients Undergoing Anterior Cruciate Ligament Repair
Knee surgeries are associated with severe postoperative pain. Blocking the femoral nerve (or saphenous nerve) in the adductor canal is increasingly used for knee analgesia.
- Trial name
- NCT04443634
- Testing
- Ultrasound Guided Adductor Canal Block, Ultrasound Guided Saphenous Nerve Block, General anesthesia
- Where
- Egypt
- Volunteers
- 88 people
- Sponsor
- Cairo University
Flexible Fiberoptic Bronchoscopy Versus Flexible Intubation Video Endoscope FIVE in Obese Patients
Comparison of Endotracheal Intubation Using Flexible Fiberoptic Bronchoscopy Versus Flexible Intubation Video Endoscope (FIVE) in Obese Patients Undergoing Elective Surgeries Under General Anesthesia: A Randomized Controlled Trial
Tracheal intubation is one of the most common medical procedures performed in hospitals. On one hand, it is highly successful and easy to perform using a rigid laryngoscope.
- Trial name
- NCT03423563
- Testing
- Flexible fiberoptic bronchoscopy, Fexible intubation video endoscopy
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Cairo University
Ventilation, Lung Function
Respiratory Effects of Flow-Controlled Ventilation and Jet Ventilation in Patients Undergoing Laryngotracheal Surgery
Laryngotracheal surgery often requires a small diameter endotracheal tube to oxygenate patients under general anesthesia. Oxygenation is often only possible with high-frequency jet ventilators due to the use of small diameter and…
- Conditions
- Ventilation, Lung Function, Anesthesia, General
- Trial name
- Flowjet (NCT06063798)
- Testing
- General anesthesia for laryngotracheal surgery, Mechanical ventilation by FCV, Mechanical ventilation by HFJV
- Where
- Switzerland
- Volunteers
- 50 people
- Sponsor
- University Hospital, Geneva
Hemodynamics, Transcatheter Aortic Valve Replacement
Efficacy and Safety of Ciprofol for General Anaesthesia in Patients Undergoing Transcatheter Aortic Valve Replacement
Aortic valve stenosis is the most common debilitating valvular heart lesion in old patients. Transcatheter aortic valve replacement (TAVR) is an emergent technique for high-risk patients with aortic stenosis.
- Conditions
- Hemodynamics, Transcatheter Aortic Valve Replacement, General Anesthesia, Post-induction Hypotension
- Trial name
- NCT05881291
- Testing
- ciprofol, propofol
- Where
- China
- Volunteers
- 124 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Glycopyrrolate
Effect of Perioperative Use of Glycopyrrolate on Lung Function in Patients Under General Anesthesia
Gastrointestinal tumor is one of the highest incidence of malignant tumors in our country, with the incidence increasing year by year.
- Trial name
- NCT05693246
- Testing
- Glycopyrrolate, normal saline
- Where
- China
- Volunteers
- 52 people
- Sponsor
- Zhuan Zhang
Anesthesia, General
Efficacy and Safety of Ciprofol Compared to Propofol for Nonintubated General Anesthesia in Patients Undergoing TAVR
The purpose of this study is to explore the efficacy and safety of ciprofol compared to propofol for non-intubated general anesthesia in patients undergoing transcatheter aortic valve replacement (TAVR).
- Trial name
- NCT05035069
- Testing
- Ciprofol, Propofol
- Where
- China
- Volunteers
- 24 people
- Sponsor
- Haisco Pharmaceutical Group Co., Ltd.