Clinical trials: Patients Undergoing General Anesthesia
General Anesthesia; Pediatric Surgery; Intraoperative Music Therapy; Operating Room Noise Reduction; Anesthetic Requirement; Analgesic Requirement
Effect of Intraoperative Instrumental Music and Operating Room Noise Reduction on Anesthetic and Analgesic Requirements in Pediatric Patients Aged 3-18 Years Undergoing Surgery Under General Anesthesia: A Randomized Controlled Trial
This randomized controlled clinical trial aims to evaluate the effects of intraoperative instrumental music and operating room noise reduction on anesthetic and analgesic requirements in pediatric patients aged 3-18 years…
- Trial name
- MUSIC-OR (NCT07630675)
- Volunteers
- 180 people
- Sponsor
- Ankara City Hospital Bilkent
Cholecystectomy, Laparoscopic, Gynecologic Surgical Procedures
Synergistic Effect of Intravenous Lidocaine on Anesthetic Induction and Emergence in Patients Undergoing Laparoscopic Cholecystectomy or Gynecological Surgery
This study aims to evaluate the effect of intravenous lidocaine on consciousness changes during anesthesia in patients undergoing laparoscopic cholecystectomy or gynecologic surgery.
- Conditions
- Cholecystectomy, Laparoscopic, Gynecologic Surgical Procedures, Anesthesia and Procedure Related Time Intervals
- Trial name
- Li (NCT07193836)
- Testing
- Normal Saline (0.9% NaCl), Lidocaine, Lidocaine Bolus + Infusion
- Where
- China
- Volunteers
- 195 people
- Sponsor
- General Hospital of Ningxia Medical University
Bariatric Surgery
Efficacy and Safety of Ciprofol in Laparoscopic Sleeve Gastrectomy
To evaluate the efficacy and safety of ciprofol for the induction of general anesthesia in obese patients undergoing laparoscopic sleeve gastrectomy.
- Trial name
- NCT05522998
- Testing
- Ciprofol, Propofol
- Where
- China
- Volunteers
- 212 people
- Sponsor
- The Third People's Hospital of Chengdu
Pain Management
Opioid-free Anesthesia as an Alternative to General Anesthesia in Patients Undergoing Duodenopancreatic Surgery by Laparotomy.
Opioid-free anesthesia is not associated with greater pain than opioid anesthesia and reduces the need for opioids in the postoperative period.
- Trial name
- NCT07364864
- Testing
- Opioid, OFA
- Where
- Poland
- Volunteers
- 200 people
- Sponsor
- Jagiellonian University
Anesthesia; Hypothermia
Comparison of the Effect of Remimazolam With Sevoflurane on Postanesthetic Shivering
The incidence of postanesthetic shivering (PAS) after general anesthesia is affected by the anesthesia maintenance agents. This study compared the effect of remimazolam with sevoflurane on PAS in patients with laparoscopic…
- Trial name
- NCT05523037
- Testing
- Sevoflurane, Remimazolam
- Where
- South Korea
- Volunteers
- 74 people
- Sponsor
- Wonkwang University Hospital
Ischemic Stroke, Anesthesia
The Effect of Sedoanalgesia and General Anaesthesia on Early Neurological Recovery in Acute Ischaemic Stroke Patients Undergoing Endovascular Thrombectomy
The hypothesis of this study is that sedoanalgesia will provide better early neurological recovery than general anaesthesia in acute ischaemic stroke patients undergoing endovascular thrombectomy and to investigate the…
- Conditions
- Ischemic Stroke, Anesthesia, Neurologic Symptoms
- Trial name
- NCT06183567
- Testing
- Sedoanalgesia, general anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 62 people
- Sponsor
- Umraniye Education and Research Hospital
Arrhythmia, Cardiac, Kidney Cancer
Cardiac Arrhythmias in Patients Undergoing Kidney Cancer Surgery Depending on the Anaesthesia Method
This study evaluates the incidence of cardiac arrhythmias during the perioperative period in patients undergoing open kidney cancer surgery in the lateral position.
- Conditions
- Arrhythmia, Cardiac, Kidney Cancer, Surgery, Anesthesia, Local
- Trial name
- NCT02988219
- Testing
- Bupivacaine-fentanyl, Holter ECG monitor, Open kidney cancer surgery
- Where
- Poland
- Volunteers
- 50 people
- Sponsor
- Medical University of Warsaw
Anesthesia,General, Cardiac Event
Hemodynamic Parameters and Cardiac Enzyme Levels in Patients Undergoing General Anesthesia
The goal of this observational study is to learn about the effects of total intravenous general anesthesia with target controlled infusion and sevoflurane based balanced general anesthesia on hemodynamic parameters and cardiac…
- Trial name
- NCT05598567
- Testing
- target controlled infusion - total intravenous general anesthesia, sevoflurane based balanced general anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Duzce University
Adult Patients Undergoing Elective Surgery With General Anesthesia and LMA Insertion
Comparison Between Lidocaine Inhalation and Intravenous Dexamethasone in Reducing Pain After Laryngeal Mask Insertion
This study aimed to compare the efficacy between lidocaine inhalation vs intravenous dexamethasone to reduce pain after laryngeal mask insertion
- Trial name
- NCT03139591
- Testing
- lidocaine inhalation; intravenous dexamethasone
- Where
- Indonesia
- Volunteers
- 196 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia
Coronary Artery Disease, Delirium
The PATHFINDER Study: A Feasibility Trial
The main purpose of this study is to determine whether a rational strategy of EEG guided multimodal general anesthesia using target specific sedative and analgesics could result in enhanced recovery after anesthesia and surgery…
- Trial name
- PATHFINDER (NCT04016740)
- Testing
- Ropivacaine, Ketamine, Remifentanil
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Beth Israel Deaconess Medical Center
Postoperative Pain
EXORA vs ESP Blocks in Laparoscopic Cholecystectomy
Laparoscopic cholecystectomy is still considered the gold standard for the surgical management of gallbladder disease due to its minimally invasive nature, shorter recovery time, and reduced postoperative complications.
- Trial name
- NCT07187310
- Testing
- EXORA block, Erector Spinae Plane block
- Where
- Egypt
- Volunteers
- 114 people
- Sponsor
- Fayoum University Hospital
Post Operative Pain
Postoperative Analgesia in Patients Undergoing Elective Lumbar Fusion Operations Under General Anesthesia
It was proven that intrathecal opioids are considered as an effective means of pain control in several major surgical interventions including spine surgeries.
- Trial name
- NCT05338320
- Testing
- Ultrasound Guided Erector Spinae Plane Block, Intrathecal morphine, General anesthesia using intravenous fentanyl (1µg/kg)
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Ain Shams University
Urologic Neoplasms, Benign Prostatic Hyperplasia
Spinal Versus General Anesthesia in Open Simple Prostatectomy
Open simple prostatectomy is still performed for selected patients with benign prostatic hyperplasia, particularly in cases with large prostate volume.
- Conditions
- Urologic Neoplasms, Benign Prostatic Hyperplasia, Anesthesia
- Trial name
- NCT07643415
- Testing
- Spinal anesthesia, General anesthesia
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Hitit University
Skin Sympathetic Nerve Activity During General Anesthesia in Patients Undergoing Breast Cancer Surgery
Measurement of the Skin Sympathetic Nerve Activity
Sympathetic nerve activity can be measured transcutaneously in awake patients by computer-based filtering of raw signal obtained via skin leads attached on the chest.
- Trial name
- NCT03658057
- Testing
- Rocuronium
- Where
- South Korea
- Volunteers
- 20 people
- Sponsor
- Seoul National University Hospital
General Anesthesia, Blood Pressure
Assessment of Effectiveness of Continuous Non-invasive Haemodynamic Monitor by Compared to Invasive Blood Pressure and Pulse Oximeter Monitoring on Patients Undergoing General Anesthesia Surgeries for More Than 60 Minutes
The goal of this observational study is to assess whether the continuous non-invasive haemodynamic monitor MOH200 (measuring blood pressure as well as pulse rate) is effective or not in people undergoing general anesthetic…
- Conditions
- General Anesthesia, Blood Pressure, Pulse Rate, Arterial Line
- Trial name
- NCT06383000
- Volunteers
- 55 people
- Sponsor
- BLZ Technology (Wuhan) Co.,Ltd
Cataract
General Anesthesia on Blood Pressure and Intraocular Pressure in Geriatric Patients Undergoing Cataract Surgery
The primary aim of the study is to investigate the correlation between preoperative hemodynamics and frailty scores in patients undergoing cataract surgery under general anesthesia.
- Trial name
- NCT06482996
- Testing
- Intraocular pressure (IOP) was measured
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Umraniye Education and Research Hospital
Post Operative Delirium
Effect of Anesthesia on Post-operative Delirium in Elderly Patients Undergoing Hip Fracture Surgery
The purpose of this study is evaluate postoperative delirium after general anesthesia and regional anesthesia in elderly patients undergoing hip fracture surgery.
- Trial name
- RAGADelirium (NCT02213380)
- Testing
- method of anesthesia
- Where
- 13 sites in China
- Volunteers
- 950 people
- Sponsor
- Wenzhou Medical University
Laparoscopic Surgery
Effects of Continuous Dexmedetomidine Infusion on Systemic Microvascular Function in Laparoscopic Cholecystecthomy
The microcirculation represents the primary site of exchange of oxygen and nutrients for tissues, and the preservation of microcirculatory perfusion is essential for the maintenance of organ function.
- Trial name
- NCT04946396
- Testing
- dexmedetomidine intravenous infusion, 0.9%sodium chloride
- Where
- Brazil
- Volunteers
- 64 people
- Sponsor
- National Institute of Cardiology, Laranjeiras, Brazil
Stroke, Endovascular Repair
GA vs. CS for Endovascular Stroke Therapy
After a stroke caused by a blockage (clot) in a blood vessel in the brain, patients may have the clot removed by threading a catheter from the groin up to the affected area of the brain.
- Conditions
- Stroke, Endovascular Repair, Anesthesia
- Trial name
- NCT03247998
- Testing
- General Anesthesia, Conscious Sedation with Remifentanil
- Volunteers
- 20 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Hernia Abdominal Wall
Remifentanil in Deep vs Moderate Neuromuscular Blocks During Surgical Pleth Index-guided Anesthesia for Laparoscopic Herniorrhaphy
The primary purpose of this study is to compare the remifentanil requirements in deep versus moderate neuromuscular blocks during the surgical pleth index -guided anesthesia in patients undergoing laparoscopic herniorrhaphy.
- Trial name
- NCT04022733
- Testing
- Moderate neuromuscular block, Deep neuromuscular block
- Where
- South Korea
- Volunteers
- 134 people
- Sponsor
- Ajou University School of Medicine