Clinical trials: Patients With Anorexia Nervosa
Anorexia Nervosa
Family Therapy and Anorexia Nervosa : Which is the Best Approach?
The aim of this study is to evaluate whether the implementation of Multiple Family Therapy (MFT) within a multi-disciplinary treatment program for Anorexia Nervosa (AN) in adolescence is at least as effective in terms of clinical…
- Trial name
- THERAFAMBEST (NCT03350594)
- Testing
- Systemic Family Therapy, Multiple Family Therapy
- Where
- 5 sites in France
- Volunteers
- 177 people, healthy volunteers welcome
- Sponsor
- Institut Mutualiste Montsouris
Eating Disorders, Anorexia Nervosa
Exposure Therapy Study In Adults With Eating Disorders
The current proposal will evaluate the feasibility, acceptability, and preliminary efficacy of Exposure Therapy for anorexia nervosa (AN) spectrum disorders (Exp-AN), an innovative treatment rooted in principles of inhibitory…
- Trial name
- NCT06171711
- Testing
- Exposure Therapy
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Milton S. Hershey Medical Center
Atypical Anorexia Nervosa
Individualized Study of Refeeding to Optimize iNpatient Gains
The primary purpose of the trial is to compare the efficacy and safety of Individualized Caloric Refeeding (ICR) to the new standard of care, Higher Calorie Refeeding (HCR), in hospitalized patients with atypical anorexia nervosa…
- Trial name
- i-STRONG (NCT04966858)
- Testing
- Individualized Caloric Refeeding (ICR), Higher Calorie Refeeding (HCR)
- Where
- 2 sites in United States
- Volunteers
- 77 people
- Sponsor
- University of California, San Francisco
Eating Disorders, Anorexia Nervosa
Open vs. Blind Weighing Study In Adolescents and Young Adult With Eating Disorders
Current treatments for adolescents and young adults (AYAs) with eating disorders (EDs) do not effectively address a central ED symptom - anxiety about weight gain - which contributes to poor outcomes.
- Trial name
- NCT06085092
- Testing
- Open weighing, Blind weighing
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Milton S. Hershey Medical Center
Anorexia Nervosa
Reestablishing Normal Gut-brain Interaction in Anorexia Nervose With Normal Gut Microbiota
In this pilot study 36 patients with anorexia nervosa (AN) will be randomized to either treatment with psychotherapy as usual (TAU) or TAU plus fecal microbiota transplantation (FMT).
- Trial name
- Restart (NCT07574892)
- Testing
- Psychotherapy as usual combined with single dose normal gut microbiota, Psychotherapy treatment as usual (TAU)
- Where
- 4 sites in Norway
- Volunteers
- 36 people
- Sponsor
- Haukeland University Hospital
Anorexia Nervosa
Impact of Fatty Stimuli on Cerebral Activity in Anorexia Nervosa: a Multi-sensory Approach
Lipid restriction is significant in anorexia nervosa and limits therapeutic management. The multisensory perception of fat is altered, creating an aversion to lipids.
- Trial name
- ANOVERSION (NCT07344831)
- Testing
- MRI examination, Smell and taste capacity testings
- Where
- France
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Anorexia Nervosa
Impairment of Central Coherence in Restrictive Anorexia Nervosa (CoCA)
The current etiological pathological model of anorexia nervosa is poly-factorial involving individual genetic and psychological factors, in close interaction with environmental, family and socio-cultural factors.
- Trial name
- CoCA (NCT02381639)
- Testing
- One interview of 90 minutes with a part of cognitive assessment and a part of self-assessment
- Where
- France
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- Nantes University Hospital
Anorexia Nervosa
Efficacy of Non-invasive Vagus Nerve Stimulation for Treatment of Low Weight Eating Disorders
This project includes a 4-week randomized trial comparing pre-meal vagal nerve stimulation (taVNS) to pre-meal sham stimulation.
- Trial name
- NCT05554172
- Testing
- taVNS
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Autism, Anorexia Nervosa
Neural Correlates of Autistic Individuals With Anorexia Nervosa
Masking is a behaviour or strategy used by many Autistic people to appear non-Autistic and blend in with a neurotypical society.
- Trial name
- NCT07098156
- Testing
- Single Research Visit 3T MRI Research Scan, Demographic and Behavioural Questionnaires
- Where
- 2 sites in United Kingdom
- Volunteers
- 29 people
- Sponsor
- University of Aberdeen
Eating Disorders, Anorexia Nervosa
Facing Eating Disorder Fears for Anorexia Nervosa
FED-F is a modular treatment that enhances exposure therapy with psychoeducation and cognitive skills teaching how to face fears of (a) food, (b) weight gain, (c) interoception/body, and (d) social situations.
- Conditions
- Eating Disorders, Anorexia Nervosa, Anorexia Nervosa in Remission
- Trial name
- FED-F (NCT05596799)
- Testing
- Facing Eating Disorder Fears Condition
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- University of Louisville
Anorexia Nervosa, Atypical, Anorexia Nervosa
Frequency of Hypermobility-Related Problems in Patients With Anorexia Nervosa
The purpose of this study is to examine the frequense of generalized hypermobility and pain in patients with Anorexia Nervosa. The study further explores two main questions: (1) whether generalized hypermobility may be an…
- Trial name
- NCT07159867
- Where
- Sweden
- Volunteers
- 100 people
- Sponsor
- Vastra Gotaland Region
Anorexia Nervosa, Caregiver Burden
Online FBT-DBT Caregiver Intervention for Caregivers of Individuals With Anorexia Nervosa
Anorexia nervosa (AN) is a severe psychiatric disorder characterized by a chronic and relapsing course. Caregivers of individuals with AN often experience substantial caregiving burden, emotional distress, and impairment in…
- Trial name
- NCT07734779
- Testing
- Online FBT-DBT Intervention, Online Supportive Psychological Intervention
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Shanghai Mental Health Center
Deep Brain Stimulation
Efficacy and Safety of Combo-stim Deep Brain Stimulation for Treatment-refractory Mental Disorders
This is a multi-center, single arm, prospective, open-label, extendable study for the efficacy and safety of combo-stim deep brain stimulation for treatment-refractory mental disorders (obsessive-compulsive disorder…
- Trial name
- NCT06112067
- Testing
- deep brain stimulation
- Where
- China
- Volunteers
- 18 people
- Sponsor
- Shanghai Mental Health Center
Functional Dyspepsia, Anorexia Nervosa
Identifying Multidimensional Signatures of Gastric Interoception in Functional Dyspepsia
This study is being conducted to investigate gut-brain communication in individuals with functional dyspepsia and anorexia nervosa.
- Trial name
- IMAGINE (NCT07772167)
- Testing
- Functional magnetic resonance imaging (fMRI)
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Anorexia Nervosa
Investigation of Multi-Family Therapy for Anorexia Nervosa
The proposed project is an intensive multi family therapy (MFT) intervention involving patients with anorexia nervosa and their families.
- Trial name
- NCT06203418
- Testing
- Multi-Family Therapy
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- University of Illinois at Chicago
Anorexia Nervosa
Safety, Therapeutic Potential, and Mechanisms of Two Psilocybin Doses, Administered With Psychological Support in Young Adults With Anorexia Nervosa
The goal of this clinical trial is to learn if psilocybin, given with psychological support, is safe and helps treat anorexia nervosa in young adults.
- Trial name
- psiAN (NCT07169747)
- Testing
- Psilocybin
- Where
- Sweden
- Volunteers
- 40 people
- Sponsor
- Region Skane
Eating Disorders, Anxiety
Non-invasive Cranial Electrical Stimulation for Mealtime Anxiety in Adults With Eating Disorders
The study is to evaluate the feasibility of using a non-invasive brain stimulation device in a sample of inpatients with eating disorders (ED).
- Trial name
- NCT07017322
- Testing
- Alpha-Stim AID
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Rogers Behavioral Health
Anorexia Nervosa, Autism
A Group Intervention for Parents of Autistic Young People With Anorexia Nervosa: An Exploration of How Parents Make Sense of and Integrate Concepts From the Group Into Family Life
The goal of this study is to understand how a group intervention for parents of autistic young people with co-occurring anorexia nervosa informs how parents support their child's recovery.
- Trial name
- NCT07757646
- Where
- United Kingdom
- Volunteers
- 6 people
- Sponsor
- King's College London
Anorexia Nervosa
Patient-derived Stem Cell Models of Anorexia Nervosa
Experimental and genetic data, as well as brain imaging, support a role of the hypothalamic Arcuate nucleus neurons and their communication with surrounding microglia in anorectic conditions, but it has until recently not been…
- Trial name
- ANSTEM (NCT06259500)
- Testing
- observational
- Where
- Sweden
- Volunteers
- 20 people
- Sponsor
- Karolinska Institutet
Anorexia Nervosa, Constitutional Leanness
Energy Intake, Exercise and Constitutional Leanness
The aim of this study will be to identify the physical and dietary profile of adult women presenting constitutional leanness (CL), comparatively with normal-weight peers and BMI-matched women with anorexia nervosa.
- Trial name
- Nutrilean (NCT03981432)
- Testing
- REST-Fixed, REST-AdLib, EX-AdLib
- Where
- France
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- University Hospital, Clermont-Ferrand