Clinical trials: Patients With Bipolar Disorders
Bipolar Disorder, Coping Skills
Acceptance and Commitment Therapy Based Psychoeducation, Meaning of Life and Coping Skills in Bipolar Disorder
This research will be conducted to determine the effect of acceptance and commitment therapy-based psychoeducation on coping skills and finding meaning in life in patients with bipolar disorder.
- Trial name
- NCT06131866
- Testing
- Psychoeducation based on Acceptance and Commitment Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Kubra TOHUMCU
Bipolar Disorder
Efficacy of N-Acetyl-Cysteine in Bipolar Disorder and Tobacco Use Disorder
Effects of N-Acetyl-Cysteine in patients with bipolar depression (primary outcome is Hamilton Depression Rating Scale) with and without tobacco use disorder and on inflammatory and oxidative stress biomarkers
- Trial name
- NACBD (NCT02252341)
- Testing
- N-Acetyl-Cysteine
- Where
- Brazil
- Volunteers
- 130 people
- Sponsor
- Universidade Estadual de Maringá
Bipolar Disorder, Bipolar Depression
Delivering Electronic Cognitive Behavioural Therapy to Patients With Bipolar Disorder and Residual Depressive Symptoms
The lifetime prevalence of Bipolar II is 0.4% with the time spent with depressive symptoms outnumbering the time spent with hypomanic symptoms by 35 to 1.
- Trial name
- NCT04664257
- Testing
- e-CBT
- Where
- Canada
- Volunteers
- 80 people
- Sponsor
- Dr. Nazanin Alavi
Bipolar Depression
Study Comparing the Tolerability of Seroquel IR With Seroquel XR in Patients With Bipolar Depression
The purpose of the study is to compare the sedation profile one hour after dose administration between Seroquel IR and Seroquel XR.
- Trial name
- NCT00926393
- Testing
- Quetiapine Immediate Release, Quetiapine Extended Release
- Volunteers
- 139 people
- Sponsor
- AstraZeneca
Bipolar Disorder
Drug-drug Interaction Study of Aripiprazole and Lamotrigine in Patients With Bipolar Type I Disorder
The purpose of this clinical research study is to learn if aripiprazole has a drug-drug interaction with lamotrigine.
- Trial name
- NCT00321516
- Testing
- aripiprazole
- Where
- 4 sites in United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Otsuka Pharmaceutical Development & Commercialization, Inc.
Bipolar Disorder
Study of Aripiprazole in Patients With Bipolar I Disorder
The purpose of this research study is to compare the efficacy of aripiprazole with placebo in combination with lithium or valproate monotherapy, in the treatment of bipolar I patients with manic or mixed episodes.
- Trial name
- NCT00257972
- Testing
- aripiprazole
- Where
- 90 sites in United States, Australia and 15 more
- Volunteers
- 400 people
- Sponsor
- Otsuka Pharmaceutical Development & Commercialization, Inc.
Bipolar I Disorder, Cognitive Impairment
Assessing the Role of Cariprazine in Improving Cognition in Euthymic Bipolar Patients
Some patients with bipolar disorder show broad cognitive impairments (e.g. difficulty with concentration, problem solving, memory etc.) that persist during euthymia (no symptoms of depression or mania) despite remission of mood…
- Trial name
- CARPZ-01 (NCT04771299)
- Testing
- Cariprazine
- Where
- Canada
- Volunteers
- 1 people
- Sponsor
- Lakshmi N Yatham
Bipolar Disorder, Elderly
Long-term Study of FK949E in Elderly Bipolar Disorder Patients
FK949E was administered to elderly bipolar disorder patients with major depressive episode for 52 weeks. Its safety, efficacy, and plasma concentration change were evaluated in an open-label manner.
- Trial name
- NCT01737268
- Testing
- FK949E
- Where
- 32 sites in Japan
- Volunteers
- 20 people
- Sponsor
- Astellas Pharma Inc
Bipolar Disorder
A Trial of Functional Remediation in Patients With Bipolar Disorder
In the last decade several evidences show that cognitive impairment is a major feature of bipolar disorder (BD), that is strongly associated with patients' functional outcome.
- Trial name
- NCT04577508
- Testing
- Functional Remediation, Treatment as usual
- Where
- Italy
- Volunteers
- 54 people
- Sponsor
- Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia
Bipolar Disorder, Affective Psychosis, Bipolar
Management of my Bipolarity Intervention in Bipolar Disorder Patients
The Management of my Bipolarity study aims to develop an educational intervention (MoB EI) on the combined use of technology and face to face education on the empowerment of ill health self-management skills in adults with…
- Conditions
- Bipolar Disorder, Affective Psychosis, Bipolar, Manic-Depressive Psychosis, Depression, Bipolar
- Trial name
- MoB (NCT04643210)
- Testing
- F2F MoB EI, MoB DP
- Where
- Cyprus
- Volunteers
- 80 people
- Sponsor
- Cyprus University of Technology
Bipolar Disorder, Alcoholism
Adjunctive Topiramate for Treatment of Alcohol Dependence in Patients With Bipolar Disorder
The purpose of this study is determine whether the use of topiramate is effective in the treatment of alcohol dependence (i.e. decreases drinking) in patients with bipolar disorder.
- Conditions
- Bipolar Disorder, Alcoholism, Alcohol Dependence
- Trial name
- NCT00572117
- Testing
- Topiramate
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Stanford University
Schizophrenia, Bipolar Disorder
A Study of the Effect of Carbamazepine on the Pharmacokinetics of Paliperidone Extended Release (ER) in Patients With Schizophrenia or Bipolar I Disorder
The purposes of this study are to evaluate the effects of a potent metabolic enzyme inducer, carbamazepine, on the steady-state pharmacokinetics of orally administered paliperidone ER and to evaluate the safety and tolerability…
- Trial name
- NCT00892125
- Testing
- paliperidone ER; Carbamazepine
- Volunteers
- 64 people
- Sponsor
- Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Bipolar II Disorder, Major Depressive Episode
Open-Label Study of Geodon in Non-Rapid Cycling Bipolar II Patients With Major Depression
The purpose of this study is to evaluate the antidepressant effectiveness of Geodon for the treatment of patients diagnosed with Bipolar II disorder who are currently experiencing a major depressive episode.
- Trial name
- NCT00237666
- Testing
- Ziprasidone
- Where
- 2 sites in United States
- Volunteers
- 30 people
- Sponsor
- The Medical Research Network
Schizophrenia, Bipolar 1 Disorder
Abilify Maintena PMS in Schizophrenia Patients or Bipolar 1 Disorder
This is a Post-Marketing Surveillance (PMS) of Abilify Maintena® Injections in accordance with Korean regulations on New Drug Re-examination (i.e.
- Trial name
- NCT03386851
- Where
- South Korea
- Volunteers
- 1,030 people
- Sponsor
- Korea Otsuka Pharmaceutical Co., Ltd.
Bipolar Disorder, Caregiver Burden
Psychiatric Nursing Intervention for Caregivers of Patients With Bipolar Disorder
This study aims to evaluate the effectiveness of an innovative psychiatric nursing intervention in reducing caregiver burden and enhancing psychological resilience and positive emotional outcomes among family caregivers of…
- Conditions
- Bipolar Disorder, Caregiver Burden, Psychological Resilience
- Trial name
- BD-Care (NCT07548359)
- Testing
- Psychiatric Nursing Intervention
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Menoufia University
Esophageal Achalasia
Safety and Efficacy of a Novel Flexible Bipolar in POEM
Per-oral endoscopic myotomy (POEM) is a minimally invasive therapy for achalasia. The procedure has demonstrated high technical and clinical success with lower adverse events.
- Trial name
- NCT06264466
- Testing
- POEM with Speedboat Ultraslim
- Where
- Ecuador
- Volunteers
- 73 people
- Sponsor
- Instituto Ecuatoriano de Enfermedades Digestivas
Bipolar 1 Disorder
Efficacy and Safety of Endoxifen in Bipolar I Disorder Patients
Bipolar disorder (BPD) is a chronic debilitating illness characterized by drastic swings in mood, energy and functional ability that affects the adult population.
- Trial name
- NCT06608641
- Testing
- Endoxifen enteric-coated tablet (8 mg)
- Where
- 12 sites in United States
- Volunteers
- 490 people
- Sponsor
- Jina Pharmaceuticals Inc.
Bipolar Disorder
Olanzapine Versus Lithium in the Treatment of Acute Depression in Patients With Bipolar II or Bipolar Not Otherwise Specified(OL Study)
Determine the efficacy and tolerability of olanzapine for treatment of acute depression in patients with bipolar II or bipolar disorder NOS compared with lithium.
- Trial name
- NCT02287259
- Testing
- olanzapine, lithium
- Where
- Japan
- Volunteers
- 50 people
- Sponsor
- Tadashi Hasegawa
Schizophrenia, Major Depressive Disorder
Clinical Registry of Patients Under Treatment With Atypical Antipsychotics
Antipsychotic drugs are characterized by blocking dopaminergic D2 receptors. They have been found to be effective and safe for the treatment of schizophrenia, bipolar disorders, depressive episodes associated with bipolar…
- Conditions
- Schizophrenia, Major Depressive Disorder, Bipolar Depressive Disorder, Parkinson's Disease With Hallucinations
- Trial name
- NCT02409823
- Testing
- Atypical Antipsychotics
- Volunteers
- 665 people
- Sponsor
- Pontifical Catholic University of Argentina
Cardio Vascular Disease, Metabolic Syndrome (MetS)
Norwegian Mental Illness Heart Health Study
Norwegian patients with severe mental illnesses (SMI), such as schizophrenia spectrum or bipolar disorder, lose on average 10 years of life compared to mentally healthy individuals. Much of this gap is due to heart disease.
- Conditions
- Cardio Vascular Disease, Metabolic Syndrome (MetS), Severe Mental Disorder, Schizophrenia and Schizophrenia Spectrum Psychosis
- Trial name
- NORMI-Heart (NCT07085923)
- Testing
- Lifestyle Intervention
- Where
- Norway
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Madeleine Elisabeth Angelsen